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Volumn 12, Issue 9, 1998, Pages 1304-1314

Defects in regulation of apoptosis in caspase-2-deficient mice

Author keywords

Apoptosis; Caspase 2; Caspases; Cell death; Ich1; Nedd2

Indexed keywords

CASPASE 2; CYSTEINE PROTEINASE; GRANZYME B; PERFORIN; UNCLASSIFIED DRUG;

EID: 0032080197     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.9.1304     Document Type: Article
Times cited : (618)

References (50)
  • 1
    • 0020971423 scopus 로고
    • The development of facial motoneurons in the mouse: Neuronal death and the innervation of the facial muscle cells
    • Ashwell, K.W. and C.R.R. Watson. 1983. The development of facial motoneurons in the mouse: Neuronal death and the innervation of the facial muscle cells. J. Embryol. Exp. Morphol. 77: 117-141.
    • (1983) J. Embryol. Exp. Morphol. , vol.77 , pp. 117-141
    • Ashwell, K.W.1    Watson, C.R.R.2
  • 3
    • 0029099845 scopus 로고
    • Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B
    • Darmon, A.J., D.W. Nicholson, and R.C. Bleackley. 1995. Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 377: 446-448.
    • (1995) Nature , vol.377 , pp. 446-448
    • Darmon, A.J.1    Nicholson, D.W.2    Bleackley, R.C.3
  • 4
    • 0027485950 scopus 로고
    • Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor
    • Deckwerth, T.L. and E.M. Johnson Jr. 1993. Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. J. Cell Biol. 123: 1207-1212.
    • (1993) J. Cell Biol. , vol.123 , pp. 1207-1212
    • Deckwerth, T.L.1    Johnson Jr., E.M.2
  • 5
    • 0030458720 scopus 로고    scopus 로고
    • Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases
    • Deshmukh, M., J. Vasilakos, T.L. Deckwerth, P.A. Lampe, B.D. Shivers, and E.M. Johnson Jr. 1996. Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases. J. Cell Biol. 135: 1341-1354.
    • (1996) J. Cell Biol. , vol.135 , pp. 1341-1354
    • Deshmukh, M.1    Vasilakos, J.2    Deckwerth, T.L.3    Lampe, P.A.4    Shivers, B.D.5    Johnson Jr., E.M.6
  • 6
    • 0031021356 scopus 로고    scopus 로고
    • RAIDD is a new 'death' adaptor molecule
    • Duan, H. and V.M. Dixit. 1997. RAIDD is a new 'death' adaptor molecule. Nature 385: 86-89.
    • (1997) Nature , vol.385 , pp. 86-89
    • Duan, H.1    Dixit, V.M.2
  • 7
    • 0028123667 scopus 로고
    • Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal
    • Edward, S.N. and A.M. Tolkovsky. 1991. Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal. J. Cell. Biol. 124: 537-546.
    • (1991) J. Cell. Biol. , vol.124 , pp. 537-546
    • Edward, S.N.1    Tolkovsky, A.M.2
  • 8
    • 0028206012 scopus 로고
    • Differential growth of the mouse preimplantation embryo in chemically defined media
    • Erbach, G.T., J.A. Lawitts, V.E. Papaioannou, and J.D. Biggers. 1994. Differential growth of the mouse preimplantation embryo in chemically defined media. Biol. Reprod. 50: 1027-1033.
    • (1994) Biol. Reprod. , vol.50 , pp. 1027-1033
    • Erbach, G.T.1    Lawitts, J.A.2    Papaioannou, V.E.3    Biggers, J.D.4
  • 9
    • 0028973301 scopus 로고
    • Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: Dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle
    • Flaws, J.A., K. Kugu, A.M. Trbovich, A. DeSanti, K.I. Tilly, A.N. Hirshfield, and J.L. Tilly. 1995. Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: Dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle. Endocrinology 136: 5042-5053.
    • (1995) Endocrinology , vol.136 , pp. 5042-5053
    • Flaws, J.A.1    Kugu, K.2    Trbovich, A.M.3    Desanti, A.4    Tilly, K.I.5    Hirshfield, A.N.6    Tilly, J.L.7
  • 11
    • 8044252166 scopus 로고    scopus 로고
    • Expression of a dominant negative mutant of ICE in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury
    • Friedlander, R.M., V. Gagliardini, H. Hara, K.B. Fink, W. Li, G. MacDonald, M.C. Fishman, A.H. Greenberg, M.A. Moskowitz, and J. Yuan. 1997b. Expression of a dominant negative mutant of ICE in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J. Exp. Med. 185: 933-940.
    • (1997) J. Exp. Med. , vol.185 , pp. 933-940
    • Friedlander, R.M.1    Gagliardini, V.2    Hara, H.3    Fink, K.B.4    Li, W.5    MacDonald, G.6    Fishman, M.C.7    Greenberg, A.H.8    Moskowitz, M.A.9    Yuan, J.10
  • 12
    • 0029760732 scopus 로고    scopus 로고
    • RIP and FADD: Two 'death domain'-containing proteins can induce apoptosis by convergent, but dissociable, pathways
    • Grimm, S., B.Z. Stanger, and P. Leder. 1996. RIP and FADD: Two 'death domain'-containing proteins can induce apoptosis by convergent, but dissociable, pathways. Proc. Natl. Acad. Sci. 93: 10923-10927.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 10923-10927
    • Grimm, S.1    Stanger, B.Z.2    Leder, P.3
  • 13
    • 0028125281 scopus 로고
    • Transgenic-mouse model of amyotrophic lateral sclerosis
    • Gurney, M.E. 1994. Transgenic-mouse model of amyotrophic lateral sclerosis. New Eng. J. Med. 331: 1721-1722.
    • (1994) New Eng. J. Med. , vol.331 , pp. 1721-1722
    • Gurney, M.E.1
  • 14
    • 0028284779 scopus 로고
    • Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
    • published erratum appears in Science 269(5221): 149. 1995
    • Gurney, M.E., H. Pu, A.Y. Chiu, M.C. Dal Canto, C.Y. Polchow, D.D. Alexander, J. Caliendo, A. Hentati, Y.W. Kwon, H.X. Deng, et al. 1994. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation [published erratum appears in Science 269(5221): 149. 1995] Science 264: 1772-1775.
    • (1994) Science , vol.264 , pp. 1772-1775
    • Gurney, M.E.1    Pu, H.2    Chiu, A.Y.3    Dal Canto, M.C.4    Polchow, C.Y.5    Alexander, D.D.6    Caliendo, J.7    Hentati, A.8    Kwon, Y.W.9    Deng, H.X.10
  • 17
    • 0030915095 scopus 로고    scopus 로고
    • Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis
    • Harvey, N.L., A.J. Butt, and S. Kumar. 1997. Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis. J. Biol. Chem. 272: 13134-13139.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13134-13139
    • Harvey, N.L.1    Butt, A.J.2    Kumar, S.3
  • 18
    • 0028258577 scopus 로고
    • Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
    • Heusel, J.W., R.L. Wesselschmidt, S. Shresta, J.H. Russell, and T.J. Ley. 1994. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 76: 977-987.
    • (1994) Cell , vol.76 , pp. 977-987
    • Heusel, J.W.1    Wesselschmidt, R.L.2    Shresta, S.3    Russell, J.H.4    Ley, T.J.5
  • 21
    • 0030756459 scopus 로고    scopus 로고
    • Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Kostic, V., V. Jackson-Lewis, F. de Bilbao, M. Dubois-Dauphin, and S. Przedborski. 1997. Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science 277: 559-562.
    • (1997) Science , vol.277 , pp. 559-562
    • Kostic, V.1    Jackson-Lewis, V.2    De Bilbao, F.3    Dubois-Dauphin, M.4    Przedborski, S.5
  • 23
    • 0028920863 scopus 로고
    • Altered cytokine export and apoptosis in mice deficient in interleukin-1b converting enzyme
    • Kuida, K., J.A. Lippke, G. Ku, M.W. Harding, D.J. Livingston, M.S.-S. Su, and R.A. Flavell. 1995. Altered cytokine export and apoptosis in mice deficient in interleukin-1b converting enzyme. Science 267: 2000-2002.
    • (1995) Science , vol.267 , pp. 2000-2002
    • Kuida, K.1    Lippke, J.A.2    Ku, G.3    Harding, M.W.4    Livingston, D.J.5    Su, M.S.-S.6    Flavell, R.A.7
  • 25
    • 0029069295 scopus 로고
    • ICE-like proteases in apoptosis
    • Kumar, S. 1995a. ICE-like proteases in apoptosis. Trends. Biochem. Sci. 20: 198-202.
    • (1995) Trends. Biochem. Sci. , vol.20 , pp. 198-202
    • Kumar, S.1
  • 26
    • 0028998012 scopus 로고
    • Inhibition of apoptosis by the expression of antisense Nedd2
    • _. 1995b. Inhibition of apoptosis by the expression of antisense Nedd2. FEBS Lett. 368: 69-72.
    • (1995) FEBS Lett. , vol.368 , pp. 69-72
  • 27
    • 0026763128 scopus 로고
    • Identification of a set of genes with developmentally down-regulated expression in the mouse brain
    • Kumar, S., Y. Tomooka, and M. Noda. 1992. Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem. Biophys. Res. Commun. 185: 1155-1161.
    • (1992) Biochem. Biophys. Res. Commun. , vol.185 , pp. 1155-1161
    • Kumar, S.1    Tomooka, Y.2    Noda, M.3
  • 28
    • 0027990778 scopus 로고
    • Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1B-converting enzyme
    • Kumar, S., M. Kinoshita, M. Noda, N.G. Copeland, and N.A. Jenkins. 1994. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1B-converting enzyme. Genes & Dev. 8:1613-1626.
    • (1994) Genes & Dev. , vol.8 , pp. 1613-1626
    • Kumar, S.1    Kinoshita, M.2    Noda, M.3    Copeland, N.G.4    Jenkins, N.A.5
  • 29
    • 0002323493 scopus 로고    scopus 로고
    • Origin, expression and possible functions of the two alternatively spliced forms of the mouse Nedd2 mRNA
    • Kumar, S., M. Kinoshita, and M. Noda. 1997. Origin, expression and possible functions of the two alternatively spliced forms of the mouse Nedd2 mRNA. Cell Death Differ. 4: 378-387.
    • (1997) Cell Death Differ. , vol.4 , pp. 378-387
    • Kumar, S.1    Kinoshita, M.2    Noda, M.3
  • 32
    • 0029125701 scopus 로고
    • Protease activation during apoptosis: Death by a thousand cuts
    • Martin, S.J. and D.R. Green. 1995. Protease activation during apoptosis: Death by a thousand cuts. Cell 82: 349-352.
    • (1995) Cell , vol.82 , pp. 349-352
    • Martin, S.J.1    Green, D.R.2
  • 33
    • 1842456916 scopus 로고    scopus 로고
    • Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development
    • Michaelidis, T.M., M. Sendtner, J.D. Cooper, M.S. Airaksinen, B. Holtmann, M. Meyer, and H. Thoenen. 1996. Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron 17: 75-89.
    • (1996) Neuron , vol.17 , pp. 75-89
    • Michaelidis, T.M.1    Sendtner, M.2    Cooper, J.D.3    Airaksinen, M.S.4    Holtmann, B.5    Meyer, M.6    Thoenen, H.7
  • 35
    • 0030694255 scopus 로고    scopus 로고
    • Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction
    • Perez, G.I., C.M. Knudson, L. Leykin, S.J. Korsmeyer, and J.L. Tilly. 1997. Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. Nature Med. 3: 1228-1232.
    • (1997) Nature Med. , vol.3 , pp. 1228-1232
    • Perez, G.I.1    Knudson, C.M.2    Leykin, L.3    Korsmeyer, S.J.4    Tilly, J.L.5
  • 36
    • 0031170966 scopus 로고    scopus 로고
    • Death substrates come alive
    • Porter, A.G., P. Ng, and R.U. Janicke. 1997. Death substrates come alive. BioEssays 19: 501-507.
    • (1997) BioEssays , vol.19 , pp. 501-507
    • Porter, A.G.1    Ng, P.2    Janicke, R.U.3
  • 37
    • 0029041065 scopus 로고
    • Analysis of G-protein-α subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach
    • Rambhatla, L., B. Patel, N. Dhanasekaran, and K.E. Latham. 1995. Analysis of G-protein-α subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach. Mol. Reprod. Dev. 41: 314-324.
    • (1995) Mol. Reprod. Dev. , vol.41 , pp. 314-324
    • Rambhatla, L.1    Patel, B.2    Dhanasekaran, N.3    Latham, K.E.4
  • 38
    • 0029118052 scopus 로고
    • Ablation of bcl-2 gene expression decreases the number of oocytes and primordial follicles established in the post-natal female mouse gonad
    • Ratts, V., J.A. Flaws, R. Kolp, C.M. Sorenson, and J.L. Tilly. 1995. Ablation of bcl-2 gene expression decreases the number of oocytes and primordial follicles established in the post-natal female mouse gonad. Endocrinology 136: 3665-3668.
    • (1995) Endocrinology , vol.136 , pp. 3665-3668
    • Ratts, V.1    Flaws, J.A.2    Kolp, R.3    Sorenson, C.M.4    Tilly, J.L.5
  • 39
    • 0026474805 scopus 로고
    • Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions
    • Shi, L., C.M. Kam, J.C. Powers, R. Aebersold, and A.H. Greenberg. 1992. Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. J. Exp. Med. 176: 1521-1529.
    • (1992) J. Exp. Med. , vol.176 , pp. 1521-1529
    • Shi, L.1    Kam, C.M.2    Powers, J.C.3    Aebersold, R.4    Greenberg, A.H.5
  • 41
    • 0026447283 scopus 로고
    • Axotomy-induced neuronal death during development
    • Snider, W.D., J.L. Elliot, and Q. Yan. 1992. Axotomy-induced neuronal death during development. J. Neurobiol. 23: 1231-1246.
    • (1992) J. Neurobiol. , vol.23 , pp. 1231-1246
    • Snider, W.D.1    Elliot, J.L.2    Yan, Q.3
  • 44
    • 0030238334 scopus 로고    scopus 로고
    • Apoptosis and ovarian function
    • Tilly, J.L. 1996. Apoptosis and ovarian function. Rev. Reprod. 1: 162-172.
    • (1996) Rev. Reprod. , vol.1 , pp. 162-172
    • Tilly, J.L.1
  • 45
    • 0030954023 scopus 로고    scopus 로고
    • The genes of cell death and cellular susceptibility to apoptosis in the ovary: A hypothesis
    • Tilly, J.L., K.I. Tilly, and G.I. Perez. 1997. The genes of cell death and cellular susceptibility to apoptosis in the ovary: A hypothesis. Cell Death Differ. 4: 180-187.
    • (1997) Cell Death Differ. , vol.4 , pp. 180-187
    • Tilly, J.L.1    Tilly, K.I.2    Perez, G.I.3
  • 46
    • 0031018396 scopus 로고    scopus 로고
    • Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells
    • Troy, C.M., L. Stefanis, L.A. Greene, and M.L. Shelanski. 1997. Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells. J. Neurosci. 17: 1911-1918.
    • (1997) J. Neurosci. , vol.17 , pp. 1911-1918
    • Troy, C.M.1    Stefanis, L.2    Greene, L.A.3    Shelanski, M.L.4
  • 47
    • 0029966363 scopus 로고    scopus 로고
    • Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
    • Tu, P.H., P. Raju, K.A. Robinson, M.E. Gurney, J.Q. Trojanowski, and V.M. Lee. 1996. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc. Natl. Acad. Sci. 93: 3155-3160.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 3155-3160
    • Tu, P.H.1    Raju, P.2    Robinson, K.A.3    Gurney, M.E.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 48
    • 0028168593 scopus 로고
    • Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death
    • Wang, L., M. Miura, L. Bergeron, H. Zhu, and J. Yuan. 1994. Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78: 739-750.
    • (1994) Cell , vol.78 , pp. 739-750
    • Wang, L.1    Miura, M.2    Bergeron, L.3    Zhu, H.4    Yuan, J.5
  • 49
    • 0025255636 scopus 로고
    • The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death
    • Yuan, J.Y. and H.R. Horvitz. 1990. The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev. Biol. 138: 33-41.
    • (1990) Dev. Biol. , vol.138 , pp. 33-41
    • Yuan, J.Y.1    Horvitz, H.R.2
  • 50
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1B-converting enzyme
    • Yuan, J., S. Shaham, S. Ledoux, H.M. Ellis, and H.R. Horvitz. 1993. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1B-converting enzyme. Cell 75: 641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.