메뉴 건너뛰기




Volumn 13, Issue 19, 1999, Pages 2514-2526

Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis

Author keywords

Apoptosis; Caspase; NF B; RIP; TNF

Indexed keywords

ASPARTIC ACID; CASPASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHOTRANSFERASE; TUMOR NECROSIS FACTOR;

EID: 0033214236     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.19.2514     Document Type: Article
Times cited : (728)

References (61)
  • 1
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi, A. and V.M. Dixit. 1998. Death receptors: Signaling and modulation. Science 281: 1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 2
    • 0032217267 scopus 로고    scopus 로고
    • IκB-NF-κB structures: At the interface of inflammation control
    • Baeuerle, P.A. 1998. IκB-NF-κB structures: At the interface of inflammation control. Cell 95: 729-731.
    • (1998) Cell , vol.95 , pp. 729-731
    • Baeuerle, P.A.1
  • 3
    • 0030271387 scopus 로고    scopus 로고
    • NF-κB: Ten years after
    • Baeuerle, P.A. and D. Baltimore. 1996. NF-κB: Ten years after. Cell 87: 13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 4
    • 0032428331 scopus 로고    scopus 로고
    • Modulation of life and death by the TNF receptor superfamily
    • Baker, S.J. and E.P. Reddy. 1998. Modulation of life and death by the TNF receptor superfamily. Oncogene 17: 3261-3270.
    • (1998) Oncogene , vol.17 , pp. 3261-3270
    • Baker, S.J.1    Reddy, E.P.2
  • 5
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-κB in preventing TNFα-induced cell death
    • Beg, A.A. and D. Baltimore. 1996. An essential role for NF-κB in preventing TNFα-induced cell death. Science 274: 782-784.
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 6
    • 0028913550 scopus 로고
    • A novel protein that interacts with the death domain of Ras/APO1 contains a sequence motif related to the death domain
    • Boldin, M.P., E.E. Varfolomeev, Z. Pancer, I.L. Mett, J.H. Camonis, and D. Wallach. 1995. A novel protein that interacts with the death domain of Ras/APO1 contains a sequence motif related to the death domain. J. Biol. Chem. 270: 7795-7798.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7795-7798
    • Boldin, M.P.1    Varfolomeev, E.E.2    Pancer, Z.3    Mett, I.L.4    Camonis, J.H.5    Wallach, D.6
  • 7
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death
    • Boldin, M.P., T.M. Goncharov, Y.V. Goltsev, and D. Wallach. 1996. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death. Cell 85: 803-815.
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 8
    • 0024503589 scopus 로고
    • Prolonged activation of jun and collagenase genes by tumor necrosis factor-alpha
    • Brenner, D.A., M. O'Hara, P. Angel, M. Chojkier, and M. Karin. 1989. Prolonged activation of jun and collagenase genes by tumor necrosis factor-alpha. Nature 337: 661-663.
    • (1989) Nature , vol.337 , pp. 661-663
    • Brenner, D.A.1    O'Hara, M.2    Angel, P.3    Chojkier, M.4    Karin, M.5
  • 9
    • 0031406386 scopus 로고    scopus 로고
    • Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway
    • Chaudhary, P.M., M. Eby, A. Jasmin, A. Bookwalter, J. Murray, and L. Hood. 1997. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway. Immunity 7: 821-830.
    • (1997) Immunity , vol.7 , pp. 821-830
    • Chaudhary, P.M.1    Eby, M.2    Jasmin, A.3    Bookwalter, A.4    Murray, J.5    Hood, L.6
  • 10
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan, A.M., K. O'Rourke, M. Tewari, and V.M. Dixit. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81: 505-512.
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3    Dixit, V.M.4
  • 11
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen, G.M. 1997. Caspases: The executioners of apoptosis. Biochem. J. 326: 1-16.
    • (1997) Biochem. J. , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 12
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • Cryns, V. and J. Yuan. 1998. Proteases to die for. Genes & Dev. 12: 1551-1570.
    • (1998) Genes & Dev. , vol.12 , pp. 1551-1570
    • Cryns, V.1    Yuan, J.2
  • 13
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    • DiDonato, J.A., M. Hayakawa, D.M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388: 548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • DiDonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 14
    • 0031021356 scopus 로고    scopus 로고
    • RAIDD is a new 'death' adapter molecule
    • Duan. H. and V.M. Dixit. 1997. RAIDD is a new 'death' adapter molecule. Nature 385: 86-89.
    • (1997) Nature , vol.385 , pp. 86-89
    • Duan, H.1    Dixit, V.M.2
  • 15
    • 0030828690 scopus 로고    scopus 로고
    • CD30-dependent degradation of TRAF2: Implications for negative regulation of TRAF signaling and the control of cell survival
    • Duckett, C.S. and C.B. Thompson. 1997. CD30-dependent degradation of TRAF2: Implications for negative regulation of TRAF signaling and the control of cell survival. Genes & Dev. 11: 2810-2821.
    • (1997) Genes & Dev. , vol.11 , pp. 2810-2821
    • Duckett, C.S.1    Thompson, C.B.2
  • 16
    • 0030973417 scopus 로고    scopus 로고
    • Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells
    • Faleiro, L., R. Kobayashi, H. Feamhead, and Y. Lazebnik. 1997. Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells. EMBO J. 16: 2271-2281.
    • (1997) EMBO J. , vol.16 , pp. 2271-2281
    • Faleiro, L.1    Kobayashi, R.2    Feamhead, H.3    Lazebnik, Y.4
  • 17
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • Hsu, H., H.-B. Shu, M-G. Pan, and D.V. Goeddel. 1996a. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84: 299-308.
    • (1996) Cell , vol.84 , pp. 299-308
    • Hsu, H.1    Shu, H.-B.2    Pan, M.-G.3    Goeddel, D.V.4
  • 18
    • 0029949257 scopus 로고    scopus 로고
    • TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
    • Hsu, H., J. Huang, H.-B. Shu, V. Baichwal, and D.V. Goeddel. 1996b. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4: 387-396.
    • (1996) Immunity , vol.4 , pp. 387-396
    • Hsu, H.1    Huang, J.2    Shu, H.-B.3    Baichwal, V.4    Goeddel, D.V.5
  • 19
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
    • Hsu, H., J. Xiong, and D.V. Goeddel. 1995. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 81: 495-504.
    • (1995) Cell , vol.81 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 20
    • 0027281373 scopus 로고
    • A novel protein domain required for apoptosis: Mutational analysis of human FAS antigen
    • Itoh, N. and S. Nagata. 1993. A novel protein domain required for apoptosis: Mutational analysis of human FAS antigen. J. Biol. Chem. 268: 10932-10937.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10932-10937
    • Itoh, N.1    Nagata, S.2
  • 21
    • 0033593655 scopus 로고    scopus 로고
    • Prevention of constitutive TNF receptor 1 signaling by silencer of death domains
    • Jiang, Y., J.D. Woronicz, W. Liu, and D. Goeddel. 1999. Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. Science 283: 543-546.
    • (1999) Science , vol.283 , pp. 543-546
    • Jiang, Y.1    Woronicz, J.D.2    Liu, W.3    Goeddel, D.4
  • 23
    • 0032033132 scopus 로고    scopus 로고
    • The death domain kinase RIP mediates the TNF-induced NF-κB signal
    • Kelliher, M.A., S. Grimm, Y. Ishida, F. Kuo, B.Z. Stanger, and P. Leder. 1998. The death domain kinase RIP mediates the TNF-induced NF-κB signal. Immunity 8: 297-303.
    • (1998) Immunity , vol.8 , pp. 297-303
    • Kelliher, M.A.1    Grimm, S.2    Ishida, Y.3    Kuo, F.4    Stanger, B.Z.5    Leder, P.6
  • 24
    • 0028102478 scopus 로고
    • Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
    • Lazebnik, Y.A., S.H. Kaufmann, S. Desnoyers, G.G. Poirier, and W.C. Earnshaw. 1994. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371: 346-347.
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 25
    • 0008206988 scopus 로고    scopus 로고
    • TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival
    • Lee, S.Y., A. Reichlin, A. Santana, K.A., Sokol, M.C. Nussenzweig, and Y. Choi. 1997. TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival. Immunity 7: 703-713.
    • (1997) Immunity , vol.7 , pp. 703-713
    • Lee, S.Y.1    Reichlin, A.2    Santana, A.3    Sokol, K.A.4    Nussenzweig, M.C.5    Choi, Y.6
  • 26
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by Caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li, H., H. Zhu, C.-J. Xu, and J. Yuan. 1998. Cleavage of BID by Caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94: 491-501.
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.-J.3    Yuan, J.4
  • 27
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo, X., I. Budihardjo, H. Zou, C. Slaughter, and X. Wang. 1998. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94: 481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 28
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
    • Liu, Z.G., H. Hsu, D.V. Goeddel, and M. Karin. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87: 565-576.
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 29
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
    • Malinin, N.L., M.P. Boldin, A.V. Kovalenko, and D. Wallach. 1997. MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 385: 540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 31
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata, S. and P. Golstein. 1995. The Fas death factor. Science 267: 1449-1456.
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 32
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata, S. 1997. Apoptosis by death factor. Cell 88: 355-365.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 34
    • 0342742310 scopus 로고
    • Tumor necrosis factor and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB
    • Osborn, L., S. Kunkel, and G.J. Nabel. 1989. Tumor necrosis factor and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB. Proc. Natl. Acad. Sci. 86: 2336-2340.
    • (1989) Proc. Natl. Acad. Sci. , vol.86 , pp. 2336-2340
    • Osborn, L.1    Kunkel, S.2    Nabel, G.J.3
  • 36
    • 0026728952 scopus 로고
    • Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme
    • Ray, C.A., R.A. Black, S.R. Kronheim, T.S. Greenstreet, P.R. Sleath, G.S. Salvessen, and D.J. Pickup. 1992. Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme. Cell 69: 587-604.
    • (1992) Cell , vol.69 , pp. 587-604
    • Ray, C.A.1    Black, R.A.2    Kronheim, S.R.3    Greenstreet, T.S.4    Sleath, P.R.5    Salvessen, G.S.6    Pickup, D.J.7
  • 37
  • 38
    • 0031048067 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-induced activation of c-jun amino-terminal kinase is mediated by TRAF2
    • Reinhard, C., B. Shamoon, V. Shyamala, and L.T. Williams. 1997. Tumor necrosis factor alpha-induced activation of c-jun amino-terminal kinase is mediated by TRAF2. EMBO J. 16: 1080-1092.
    • (1997) EMBO J. , vol.16 , pp. 1080-1092
    • Reinhard, C.1    Shamoon, B.2    Shyamala, V.3    Williams, L.T.4
  • 39
    • 0028124428 scopus 로고
    • A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 κDa tumor necrosis factor receptor
    • Rothe, M., S.C. Wong, W.J. Henzel, and D.V. Goeddel. 1994. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 κDa tumor necrosis factor receptor. Cell 78: 681-692.
    • (1994) Cell , vol.78 , pp. 681-692
    • Rothe, M.1    Wong, S.C.2    Henzel, W.J.3    Goeddel, D.V.4
  • 40
    • 0029595282 scopus 로고
    • The TNFR2-TRAF signaling complex contains two novel proteins related to baculovirus inhibitor or apoptosis proteins
    • Rothe, M., M.-G. Pan, W.J. Henzel, T.M. Ayres, and D.V. Goeddel. 1995. The TNFR2-TRAF signaling complex contains two novel proteins related to baculovirus inhibitor or apoptosis proteins. Cell 83: 1243-1252.
    • (1995) Cell , vol.83 , pp. 1243-1252
    • Rothe, M.1    Pan, M.-G.2    Henzel, W.J.3    Ayres, T.M.4    Goeddel, D.V.5
  • 42
    • 0028353492 scopus 로고
    • The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
    • Smith, C.A., T. Farrah, and R.G. Goodwin. 1994. The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death. Cell 76: 959-962.
    • (1994) Cell , vol.76 , pp. 959-962
    • Smith, C.A.1    Farrah, T.2    Goodwin, R.G.3
  • 43
    • 0032548502 scopus 로고    scopus 로고
    • Bcl-x1 functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells
    • Srinivasan, A., F. Li, A. Wong, L. Kodandapani, R. Smidt, J.F. Krebs, L.C. Fritz, J.C. Wu, and K.J. Tomaselli. 1998. Bcl-x1 functions downstream of caspase-8 to inhibit Fas-and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells. J. Biol. Chem. 273: 4523-4529.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4523-4529
    • Srinivasan, A.1    Li, F.2    Wong, A.3    Kodandapani, L.4    Smidt, R.5    Krebs, J.F.6    Fritz, L.C.7    Wu, J.C.8    Tomaselli, K.J.9
  • 44
    • 0029054725 scopus 로고
    • RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
    • Stanger, B.Z., P. Leder, T.H. Lee, E. Kim, and B. Seed, 1995. RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 81: 513-523.
    • (1995) Cell , vol.81 , pp. 513-523
    • Stanger, B.Z.1    Leder, P.2    Lee, T.H.3    Kim, E.4    Seed, B.5
  • 45
    • 0033582526 scopus 로고    scopus 로고
    • Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis
    • Sun, X.M., M. MacFarlane, J. Zhuang, B.B. Wolf, D.R. Green, and G.M. Cohen. 1999. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J. Biol. Chem. 274: 5053-5060.
    • (1999) J. Biol. Chem. , vol.274 , pp. 5053-5060
    • Sun, X.M.1    MacFarlane, M.2    Zhuang, J.3    Wolf, B.B.4    Green, D.R.5    Cohen, G.M.6
  • 47
    • 0027275490 scopus 로고
    • A novel domain within the 55 Kd TNF receptor signals cell death
    • Tartaglia, L.A., T.M. Ayres, G.H.W. Wong, and D.V. Goeddel. 1993. A novel domain within the 55 Kd TNF receptor signals cell death. Cell 74: 845-853.
    • (1993) Cell , vol.74 , pp. 845-853
    • Tartaglia, L.A.1    Ayres, T.M.2    Wong, G.H.W.3    Goeddel, D.V.4
  • 48
    • 0029858348 scopus 로고    scopus 로고
    • RIP mediates tumor necrosis factor receptor 1 activation of NF-κB but not Fas/APO-1-initiated apoptosis
    • Ting, A.T., F.X. Pimentel-Muinos, and B. Seed. 1996. RIP mediates tumor necrosis factor receptor 1 activation of NF-κB but not Fas/APO-1-initiated apoptosis. EMBO J. 15: 6189-6196.
    • (1996) EMBO J. , vol.15 , pp. 6189-6196
    • Ting, A.T.1    Pimentel-Muinos, F.X.2    Seed, B.3
  • 49
    • 0027333425 scopus 로고
    • Tumor necrosis factor, other cytokines and disease
    • Tracey, K.J. and A. Cerami. 1993. Tumor necrosis factor, other cytokines and disease. Annu. Rev. Cell Biol. 9: 317-343.
    • (1993) Annu. Rev. Cell Biol. , vol.9 , pp. 317-343
    • Tracey, K.J.1    Cerami, A.2
  • 55
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
    • Wang, C.Y., M.W. Mayo, and A.S. Baldwin, Jr. 1996. TNF-and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB. Science 274: 784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin A.S., Jr.3
  • 56
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang, C.Y., M.W. Mayo, R.G. Korneluk, D.V. Goeddel, and A.S. Baldwin, Jr. 1998. NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and C-IAP2 to suppress caspase-8 activation. Science 281: 1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin A.S., Jr.5
  • 57
    • 0032516651 scopus 로고    scopus 로고
    • IEX-1L, an apoptosis inhibitor involved in NF-κB-mediated cell survival
    • Wu, M.X., Z. Ao, K.V. Prasad, R. Wu, and S.F. Schlossman. 1998. IEX-1L, an apoptosis inhibitor involved in NF-κB-mediated cell survival. Science 281: 998-1001.
    • (1998) Science , vol.281 , pp. 998-1001
    • Wu, M.X.1    Ao, Z.2    Prasad, K.V.3    Wu, R.4    Schlossman, S.F.5
  • 60
    • 0032546387 scopus 로고    scopus 로고
    • Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
    • Zhang, J., D. Cado, A. Chen, N.H. Kabra, and A. Winoto. 1998. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392: 296-300.
    • (1998) Nature , vol.392 , pp. 296-300
    • Zhang, J.1    Cado, D.2    Chen, A.3    Kabra, N.H.4    Winoto, A.5
  • 61
    • 0032588794 scopus 로고    scopus 로고
    • NF-κB regulates Fas/APO-1/CD95- and TCR-mediated apoptosis of T lymphocytes
    • Zheng, L.X. and M. Lenardo. 1999. NF-κB regulates Fas/APO-1/CD95-and TCR-mediated apoptosis of T lymphocytes. Eur. J. Immunol. 29: 878-886.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 878-886
    • Zheng, L.X.1    Lenardo, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.