Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

Journal of Biological Chemistry

Volumn 277, Issue 1, 2002, Pages 432-438

  Hegde, Ramesh ^a   Srinivasula, Srinivasa M ^a   Zhang, Zhijia ^a   Wassell, Richard ^a   Mukattash, Rula ^a   Cilenti, Lucia ^a   Dubois, Garrett ^b   Lazebnik, Yuri ^a   Zervos, Antonis S ^a   Fernandes Alnemri, Teresa ^a   Alnemri, Emad S ^a,c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b Simons Center for Quantitative Biology   (United States)

^c UNIVERSITY OF CENTRAL FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; MASS SPECTROMETRY; PROTEINS;

APOPTOSIS;

ENZYME INHIBITION;

BINDING PROTEIN; CASPASE 9; INHIBITOR OF APOPTOSIS PROTEIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE PROTEINASE; SERINE PROTEINASE OMI; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MITOCHONDRIAL MEMBRANE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; APOPTOSIS; CASPASES; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INSECT PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; PROTEINS; SERINE ENDOPEPTIDASES;

EID: 18544386724     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M109721200     Document Type: Article

References (26)