Alterations in the apoptotic machinery and their potential role in anticancer drug resistance

Oncogene

Volumn 22, Issue 47 REV. ISS. 6, 2003, Pages 7414-7430

  Kaufmann, Scott H ^a   Vaux, David L ^b  

^a MAYO CLINIC   (United States)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Apoptosis; Bcl 2; Carcinogenesis; Caspases; Drug resistance; IAP; Stress response

Indexed keywords

ADAPTOR PROTEIN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CASPASE; CELL SURFACE RECEPTOR; CYSTEINE PROTEINASE; CYTOCHROME C; DEOXYRIBONUCLEASE; ENZYME PRECURSOR; FAS ASSOCIATED POLYPEPTIDE WITH DEATH DOMAIN PROTEIN; GLUCOCORTICOID; IMATINIB; INHIBITOR OF APOPTOSIS PROTEIN; MAMMALIAN INHIBITOR OF APOPTOSIS PROTEIN HOMOLOG A; MELANOMA INHIBITOR OF APOPTOSIS PROTEIN; METHOTREXATE; NEURONAL APOPTOSIS INHIBITORY PROTEIN; PACLITAXEL; PHOSPHOTRANSFERASE INHIBITOR; PIFITHRIN ALPHA; POLYPEPTIDE; PROTEIN BCL 2; PROTEIN INHIBITOR; PROTEIN P53; PURINE NUCLEOSIDE; RITUXIMAB; SURVIVIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; X CHROMOSOME LINKED MAMMALIAN INHIBITOR OF APOPTOSIS PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BONE MARROW TOXICITY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CARCINOGENESIS; CELL FUNCTION; CELL VIABILITY; DNA DEGRADATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME RELEASE; GASTROINTESTINAL SYMPTOM; HUMAN; IONIZING RADIATION; MITOCHONDRION; MITOSIS; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; SIDE EFFECT; SIGNAL TRANSDUCTION; SOMATIC CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; DRUG RESISTANCE, NEOPLASM; HUMANS; NEOPLASMS;

MAMMALIA;

EID: 0344393783     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206945     Document Type: Review

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