Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Nature

Volumn 430, Issue 6996, 2004, Pages 213-218

  Mariathasan, Sanjeev ^a   Hewton, Kim ^a   Monack, Denise M ^b   Vucic, Domagoj ^a   French, Dorothy M ^a   Lee, Wyne P ^a   Roose Girma, Meron ^a   Erickson, Sharon ^a   Dixit, Vishva M ^a  

^a GENENTECH INC   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; MICROORGANISMS; POLYSACCHARIDES;

MACROPHAGES; TOLL LIKE RECEPTORS (TLR);

ECOSYSTEMS;

ADENOSINE TRIPHOSPHATE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR;

MEDICINE;

ANIMAL MODEL; ARTICLE; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNE RESPONSE; INFLAMMATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM-BINDING PROTEINS; CASPASE 1; CELL DEATH; ENZYME ACTIVATION; GENE DELETION; INFLAMMATION; INTERLEUKIN-1; INTERLEUKIN-18; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASE 2; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SALMONELLA TYPHIMURIUM; SHOCK, SEPTIC;

ANIMALIA; ESCHERICHIA COLI; SALMONELLA TYPHIMURIUM;

EID: 3142654767     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02664     Document Type: Article

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