Autoproteolytic activation of pro-caspases by oligomerization

Molecular Cell

Volumn 1, Issue 2, 1998, Pages 319-325

  Yang, Xiaolu ^a   Chang, Howard Y ^a   Baltimore, David ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; CYSTEINE PROTEINASE; ENZYME PRECURSOR; FAS LIGAND; FASLG PROTEIN, HUMAN; HYBRID PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; MEMBRANE PROTEIN;

APOPTOSIS; ARTICLE; CELL FREE SYSTEM; CHEMISTRY; DIMERIZATION; ENZYMOLOGY; GENETIC TRANSFECTION; HELA CELL; HUMAN; METABOLISM; PHYSIOLOGY;

APOPTOSIS; CASPASE 1; CASPASE 3; CASPASES; CELL-FREE SYSTEM; CYSTEINE ENDOPEPTIDASES; DIMERIZATION; ENZYME PRECURSORS; FAS LIGAND PROTEIN; HELA CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 0031615875     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80032-5     Document Type: Article

References (23)

1. Alnemri, E.S., Livingston, D.J., Nicholson, D.W., Salvesen, G., Thornberry, N.A., Wong, W.W., and Yuan, J. (1996). Letter to the Editor. Human ICE/CED-3 protease nomenclature. Cell 87, 171.
2. Amara, J.F., Clackson, T., Rivera, V.M., Guo, T., Keenan, T., Natesan, S., Pollock, R., Yang, W., Courage, N.L., Holt, D.A., and Gilman, M. (1997). A versatile synthetic dimerizer for the regulation of protein-protein interactions. Proc. Natl. Acad. Sci. USA 94, 10618-10623.
3. Boldin, M.P., Goncharov, T.M., Goltsev, Y.V., and Wallach, D. (1996). Involvement of MACH, a novel MORT1/FADD interacting protease, in Fas/APO-1 and TNF receptor-induced cell death. Cell 85, 803-815.
4. Duan, H., and Dixit, V.M. (1997). RAIDD is a new 'death' adaptor molecule. Nature 385, 86-89.
5. Porter, A.G., Ng, P., and Janicke, R. (1997). Death substrates come alive. BioEssays 19, 501-507.
6. Fraser, A., and Evan, G. (1996). A license to kill. Cell 85, 781-784.
7. Hengartner, M.O. (1997). Apoptosis. CED-4 is a stranger no more. Nature 388, 714-715.
8. Henkart, P.A. (1996). ICE family proteases: mediators of all apoptotic cell death? Immunity 4, 195-201.
9. Hsu, H., Xiong, J., and Goeddel, D.V. (1995). The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 81, 495-504.
10. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S.M., Ahmad, M., Alnemri, E.S., and Wang, X. (1997). Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489.
11. Medema, J.P., Scaffidi, C., Kischkel, F.C., Shevchenko, A., Mann, M., Krammer, P.H., and Peter, M.E. (1997). FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16, 2794-2804.
12. Muzio, M., Chinnaiyan, A.M., Kischkel, F.C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J.D., Zhang, M., Gentz, R., et al. (1996). FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo1) death-inducing signaling complex. Cell 85, 817-827.
13. Muzio, M., Salvesen, G.S., and Dixit, V.M. (1997). FLICE-induced apoptosis in a cell-free system. Cleavage of caspase zymogens. J. Biol. Chem. 272, 2952-2956.
14. Nagata, S. (1997). Apoptosis by death factor. Cell 88, 355-365.
15. Ng, F.W.H., Nguyen, M., Kwan, T., Branton, P.E., Nicholson, D.W., Cromlish, J.A., and Shore, G.C. (1997). p28 bap31, a bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum. J. Cell Biol. 139, 327-338.
16. Ogasawara, J., Watanabe-Fukunaga, R., Adachi, M., Matsuzawa, A., Kasugai, T., Kitamura, Y., Itoh, N., Suda, T., and Nagata, S. (1993). Lethal effect of the anti-Fas antibody in mice. Nature 364, 806-809.
17. Salvesen, G.S., and Dixit, V.M. (1997) Caspases: intracellular signaling by proteolysis. Cell 91, 443-446.
18. Spencer, D.M., Wandless, T.J., Schreiber, S.L., and Crabtree, G.R. (1993). Controlling signal transduction with synthetic ligands. Science 262, 1019-1024.
19. Thornberry, N.A., Rano, T.A., Peterson, E.P., Rasper, D.M., Timkey, T., Garcia-Calvo, M., Houtzager, V.M., Nordstrom, P.A., Roy, S., Vaillancourt, J.P., et al. (1997). A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272, 17907-17911.
20. Ullrich, A., and Schlessinger, J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.
21. Xue, D., Shaham, S., and Horvitz, H.R. (1996). The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease. Genes Dev. 10, 1073-1083.
22. Yang, X., Khosravi-Far, R., Chang, H.Y., and Baltimore, D. (1997). Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89, 1067-1076.
23. Zhou, Q., and Salvesen, G.S. (1997). Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. Biochem. J. 324, 361-364.