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Volumn 3, Issue 5, 2003, Pages 371-382

NODS: Intracellular proteins involved in inflammation and apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INHIBITOR; CRYOPYRIN; CYTOPLASM PROTEIN; MHC CLASS II TRANSACTIVATOR; NEURONAL APOPTOSIS INHIBITORY PROTEIN 5; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN 1; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN 2; PROTEIN; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; CARD15 PROTEIN, HUMAN; CARD4 PROTEIN, HUMAN; CARRIER PROTEIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 0038624558     PISSN: 14741733     EISSN: None     Source Type: Journal    
DOI: 10.1038/nri1086     Document Type: Review
Times cited : (890)

References (115)
  • 1
    • 0035859020 scopus 로고    scopus 로고
    • Plant pathogens and integrated defence responses to infection
    • Dangl, J. L. & Jones, J. D. Plant pathogens and integrated defence responses to infection. Nature 411, 826-833 (2001).
    • (2001) Nature , vol.411 , pp. 826-833
    • Dangl, J.L.1    Jones, J.D.2
  • 2
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov, R. Toll-like receptors and innate immunity. Nature Rev. Immunol. 1, 135-145 (2001).
    • (2001) Nature Rev. Immunol. , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 3
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira, S., Takeda, K. & Kaisho, T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nature Immunol. 2, 675-680 (2001).
    • (2001) Nature Immunol. , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 4
    • 0035956931 scopus 로고    scopus 로고
    • Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing
    • Aballay, A. & Ausubel, F. M. Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing. Proc. Natl Acad. Sci. USA 98, 2735-2739 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2735-2739
    • Aballay, A.1    Ausubel, F.M.2
  • 5
    • 0033375493 scopus 로고    scopus 로고
    • The molecular mechanism of programmed cell death in C. elegans
    • Liu, Q. A. & Hengartner M. O. The molecular mechanism of programmed cell death in C. elegans. Ann. NY Acad. Sci. 887, 92-104 (1999).
    • (1999) Ann. NY Acad. Sci. , vol.887 , pp. 92-104
    • Liu, Q.A.1    Hengartner, M.O.2
  • 6
    • 0035913975 scopus 로고    scopus 로고
    • Caenorhabditis elegans p53: Role in apoptosis, meiosis, and stress resistance
    • Derry, W. B., Putzke, A. P. & Rothman, J. H. Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance. Science 294, 591-595 (2001).
    • (2001) Science , vol.294 , pp. 591-595
    • Derry, W.B.1    Putzke, A.P.2    Rothman, J.H.3
  • 7
    • 0033230617 scopus 로고    scopus 로고
    • PKR a sentinel kinase for cellular stress
    • Williams, B. R. PKR; a sentinel kinase for cellular stress. Oncogene 18, 6112-6120 (1999).
    • (1999) Oncogene , vol.18 , pp. 6112-6120
    • Williams, B.R.1
  • 8
    • 0034675856 scopus 로고    scopus 로고
    • A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR
    • Nanduri, S., Rahman, F., Williams, B. R. & Qin, J. A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR. EMBO J. 19, 5567-5574 (2000)
    • (2000) EMBO J. , vol.19 , pp. 5567-5574
    • Nanduri, S.1    Rahman, F.2    Williams, B.R.3    Qin, J.4
  • 9
    • 0034661989 scopus 로고    scopus 로고
    • Invasive Shigella flexneri activates NF-κB through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells
    • Philpott, D. J., Yamaoka, S., Israel, A. & Sansonetti, P. J. Invasive Shigella flexneri activates NF-κB through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells. J. Immunol. 165, 903-914 (2000).
    • (2000) J. Immunol. , vol.165 , pp. 903-914
    • Philpott, D.J.1    Yamaoka, S.2    Israel, A.3    Sansonetti, P.J.4
  • 10
  • 11
    • 0035474227 scopus 로고    scopus 로고
    • The NOD a signaling module that regulate apoptosis and host defense against pathogens
    • Inohara, N. & Nuñez, G. The NOD: a signaling module that regulate apoptosis and host defense against pathogens. Oncogene 20, 6473-6481 (2001).
    • (2001) Oncogene , vol.20 , pp. 6473-6481
    • Inohara, N.1    Nuñez, G.2
  • 12
    • 0036160150 scopus 로고    scopus 로고
    • Nods: A family of cytosolic proteins that regulate the host response to pathogens
    • Inohara, N., Ogura, Y. & Nuñez, G. Nods: a family of cytosolic proteins that regulate the host response to pathogens. Curr. Opin. Microbiol. 5, 76-80 (2002).
    • (2002) Curr. Opin. Microbiol. , vol.5 , pp. 76-80
    • Inohara, N.1    Ogura, Y.2    Nuñez, G.3
  • 13
    • 0037216780 scopus 로고    scopus 로고
    • The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations
    • Hull, K. M., Shoham, N., Chae, J. J., Aksentijevich, I. & Kastner, D. L. The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations. Curr. Opin. Rheumatol. 15, 61-69 (2003).
    • (2003) Curr. Opin. Rheumatol. , vol.15 , pp. 61-69
    • Hull, K.M.1    Shoham, N.2    Chae, J.J.3    Aksentijevich, I.4    Kastner, D.L.5
  • 14
    • 0032568168 scopus 로고    scopus 로고
    • The NB-ARC domain: A novel signalling motif shared by plant resistance gene products and regulators of cell death in animals
    • van der Biezen, E. A. & Jones, J. D. The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr. Biol. 8, R226-R227 (1998).
    • (1998) Curr. Biol. , vol.8
    • Van der Biezen, E.A.1    Jones, J.D.2
  • 15
    • 0032509354 scopus 로고    scopus 로고
    • WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation
    • Hu, Y., Ding, L., Spencer, D. M. & Nuñez, G. WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation. J. Biol. Chem. 273, 33489-33494 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 33489-33494
    • Hu, Y.1    Ding, L.2    Spencer, D.M.3    Nuñez, G.4
  • 17
    • 0032575723 scopus 로고    scopus 로고
    • Essential role of CED-4 oligomerization in CED-3 activation and apoptosis
    • Yang, X., Chang, H. Y. & Baltimore, D. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. Science 281, 1355-1357 (1998).
    • (1998) Science , vol.281 , pp. 1355-1357
    • Yang, X.1    Chang, H.Y.2    Baltimore, D.3
  • 18
    • 0034194079 scopus 로고    scopus 로고
    • The NACHT family - A new group of predicted NTPases implicated in apoptosis and MHC transcription activation
    • Koonin, E. V. & Aravind, L. The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem. Sci. 25, 223-224 (2000).
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 223-224
    • Koonin, E.V.1    Aravind, L.2
  • 19
    • 0034649566 scopus 로고    scopus 로고
    • Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
    • The Arabidopsis Genome Initiative. Analysis of the genome sequence of the flowering plant Arabidopsis thaliana. Nature 408, 796-820 (2000).
    • (2000) Nature , vol.408 , pp. 796-820
  • 20
    • 0037023349 scopus 로고    scopus 로고
    • A draft sequence of the rice genome (Oryza sativa L. ssp. japonica)
    • Goff, S. A. et al. A draft sequence of the rice genome (Oryza sativa L. ssp. japonica). Science 296, 92-100 (2002).
    • (2002) Science , vol.296 , pp. 92-100
    • Goff, S.A.1
  • 21
    • 0030954209 scopus 로고    scopus 로고
    • The CARD domain: A new apoptotic signaling motif
    • Hofmann, K., Bucher, P. & Tschopp, J. The CARD domain: a new apoptotic signaling motif. Trends Biochem. Sci. 22, 155-156 (1997).
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 155-156
    • Hofmann, K.1    Bucher, P.2    Tschopp, J.3
  • 22
    • 0034520137 scopus 로고    scopus 로고
    • The PYRIN domain: A novel motif found in apoptosis and inflammation proteins
    • Bertin, J. & DiStefano, P. S. The PYRIN domain: a novel motif found in apoptosis and inflammation proteins. Cell Death Differ. 12, 1273-1274 (2000).
    • (2000) Cell Death Differ. , vol.12 , pp. 1273-1274
    • Bertin, J.1    DiStefano, P.S.2
  • 23
    • 0035916324 scopus 로고    scopus 로고
    • The pyrin domain: A possible member of the death domain-fold family implicated in apoptosis and inflammation
    • Martinon, F., Hofmann, K. & Tschopp, J. The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation. Curr. Biol. 11, R118-R120 (2001).
    • (2001) Curr. Biol. , vol.11
    • Martinon, F.1    Hofmann, K.2    Tschopp, J.3
  • 24
    • 0035253022 scopus 로고    scopus 로고
    • The DAPIN family: A novel domain links apoptotic and interferon response proteins
    • Staub, E., Dahl, E. & Rosenthal, A. The DAPIN family: a novel domain links apoptotic and interferon response proteins. Trends Biochem. Sci. 26, 83-85 (2001).
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 83-85
    • Staub, E.1    Dahl, E.2    Rosenthal, A.3
  • 25
    • 0035253123 scopus 로고    scopus 로고
    • PAAD - A new protein domain associated with apoptosis, cancer and autoimmune diseases
    • Pawlowski, K., Pio, F., Chu, Z., Reed, J. C. & Godzik, A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem. Sci. 26, 85-87 (2001).
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 85-87
    • Pawlowski, K.1    Pio, F.2    Chu, Z.3    Reed, J.C.4    Godzik, A.5
  • 26
    • 0033532091 scopus 로고    scopus 로고
    • Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-κB
    • Bertin, J. et al. Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-κB. J. Biol. Chem. 274, 12955-12958 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 12955-12958
    • Bertin, J.1
  • 27
    • 0033591330 scopus 로고    scopus 로고
    • Nod1, an Apaf1-like activator of caspase-9 and nuclear factor-κB
    • Inohara, N. et al. Nod1, an Apaf1-like activator of caspase-9 and nuclear factor-κB. J. Biol. Chem. 274, 14560-14567 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 14560-14567
    • Inohara, N.1
  • 28
    • 0035895992 scopus 로고    scopus 로고
    • Nod2, a Nod1/Apaf1 family member that is restricted to monocytes and activates NF-κB
    • Ogura, Y. et al. Nod2, a Nod1/Apaf1 family member that is restricted to monocytes and activates NF-κB. J. Biol. Chem. 276, 4812-4818 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 4812-4818
    • Ogura, Y.1
  • 29
    • 0037192793 scopus 로고    scopus 로고
    • PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-κB
    • Manji, G. A. et al. PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-κB. J. Biol. Chem. 277, 11570-11575 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 11570-11575
    • Manji, G.A.1
  • 30
    • 0037436868 scopus 로고    scopus 로고
    • Regulation of Cryopyrin/Pypaf1 signaling by pyrin, the familial mediterranean fever gene product
    • Dowds, A. et al. Regulation of Cryopyrin/Pypaf1 signaling by pyrin, the familial mediterranean fever gene product. Biochem. Biophys. Res. Commun. 302, 575-580 (2003).
    • (2003) Biochem. Biophys. Res. Commun. , vol.302 , pp. 575-580
    • Dowds, A.1
  • 31
    • 0037108346 scopus 로고    scopus 로고
    • Cutting edge. CATERPILLER: A large family of mammalian genes containing CARD, pyrin, nuclectide-binding, and leucine-rich repeat domains
    • Harton, J. A. Linhoff, M. W., Zhang, J. & Ting, J. P. Cutting edge. CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nuclectide-binding, and leucine-rich repeat domains. J. Immunol. 169, 4088-4093 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 4088-4093
    • Harton, J.A.1    Linhoff, M.W.2    Zhang, J.3    Ting, J.P.4
  • 32
    • 0034815799 scopus 로고    scopus 로고
    • Human CARD12 is a novel CED4/Apaf 1 family member that induces apoptosis
    • Geddes, B. J. et al. Human CARD12 is a novel CED4/Apaf1 family member that induces apoptosis. Biochem. Biophys. Res. Commun. 284, 77-82 (2001).
    • (2001) Biochem. Biophys. Res. Commun. , vol.284 , pp. 77-82
    • Geddes, B.J.1
  • 33
    • 0035958867 scopus 로고    scopus 로고
    • Identification Of Ipaf, a human caspase-1-activating protein related to Apaf1
    • Poyet, J. L. et al. Identification Of Ipaf, a human caspase-1- activating protein related to Apaf1. J. Biol. Chem. 276, 28309-28313 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 28309-28313
    • Poyet, J.L.1
  • 34
    • 0034964518 scopus 로고    scopus 로고
    • Clan, a novel human Ced-4-like gene
    • Damiano, J. S. et al. Clan, a novel human Ced-4-like gene. Genomics 75, 77-83 (2001).
    • (2001) Genomics , vol.75 , pp. 77-83
    • Damiano, J.S.1
  • 35
    • 0035937775 scopus 로고    scopus 로고
    • Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins
    • Hlaing, T. et al. Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins. J. Biol. Chem. 276, 9230-9238 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 9230-9238
    • Hlaing, T.1
  • 36
    • 0035937797 scopus 로고    scopus 로고
    • A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis
    • Chu, Z. L. et al. A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis. J. Biol. Chem. 276, 9239-9245 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 9239-9245
    • Chu, Z.L.1
  • 37
    • 0035179970 scopus 로고    scopus 로고
    • Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
    • Hoffman, H. M., Mueller, J. L., Broide, D. H., Wanderer, A. A. & Kolodner, R. D. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nature Genet. 29, 301-305 (2001). The first evidence for a genetic association between cryopyrin and the development of familial cold urticaria and Muckle-Wells syndrome.
    • (2001) Nature Genet. , vol.29 , pp. 301-305
    • Hoffman, H.M.1    Mueller, J.L.2    Broide, D.H.3    Wanderer, A.A.4    Kolodner, R.D.5
  • 38
    • 0010464874 scopus 로고    scopus 로고
    • PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-κB and caspase-1-dependent cytokine processing
    • Wang, L. et al. PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-κB and caspase-1-dependent cytokine processing. J. Biol. Chem. 277, 29874-29880 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 29874-29880
    • Wang, L.1
  • 39
    • 18644368579 scopus 로고    scopus 로고
    • Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-κB and caspase-1
    • Grenier, J. M. et al. Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-κB and caspase-1. FEBS Lett. 530, 73-78 (2002).
    • (2002) FEBS Lett. , vol.530 , pp. 73-78
    • Grenier, J.M.1
  • 40
    • 0036101735 scopus 로고    scopus 로고
    • A human homologue of mouse mater, a maternal effect gene essential for early embryonic development
    • Tong, Z. B., Bondy, C. A., Zhou, J. & Nelson, L. M. A human homologue of mouse mater, a maternal effect gene essential for early embryonic development. Hum. Reprod. 17, 903-911 (2002).
    • (2002) Hum. Reprod. , vol.17 , pp. 903-911
    • Tong, Z.B.1    Bondy, C.A.2    Zhou, J.3    Nelson, L.M.4
  • 41
    • 0028896092 scopus 로고
    • The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
    • Roy, N. et al. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell. 80, 167-178 (1995).
    • (1995) Cell. , vol.80 , pp. 167-178
    • Roy, N.1
  • 42
    • 0037138841 scopus 로고    scopus 로고
    • Functional human NAIP promoter transcription regulatory elements for the NAIP and PsiNAIP genes
    • Xu, M. et al. Functional human NAIP promoter transcription regulatory elements for the NAIP and PsiNAIP genes. Biochim. Biophys. Acta 1574, 35-50 (2002).
    • (2002) Biochim. Biophys. Acta , vol.1574 , pp. 35-50
    • Xu, M.1
  • 43
    • 0035831019 scopus 로고    scopus 로고
    • Structural basis for the inhibition of caspase-3 by XIAP
    • Riedl, S. J. et al. Structural basis for the inhibition of caspase-3 by XIAP. Cell 104, 791-800 (2001).
    • (2001) Cell , vol.104 , pp. 791-800
    • Riedl, S.J.1
  • 44
    • 0034700495 scopus 로고    scopus 로고
    • Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
    • Liu, Z. et al. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature 408, 1004-1008 (2000).
    • (2000) Nature , vol.408 , pp. 1004-1008
    • Liu, Z.1
  • 45
    • 0034700491 scopus 로고    scopus 로고
    • Structural basis of IAP recognition by Smac/DIABLO
    • Wu, G. et al. Structural basis of IAP recognition by Smac/DIABLO. Nature 408, 1008-1012 (2000).
    • (2000) Nature , vol.408 , pp. 1008-1012
    • Wu, G.1
  • 46
    • 0027490172 scopus 로고
    • Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
    • Steimle, V., Otten, L. A., Zufferey, M. & Mach, B. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell 75, 135-146 (1993).
    • (1993) Cell , vol.75 , pp. 135-146
    • Steimle, V.1    Otten, L.A.2    Zufferey, M.3    Mach, B.4
  • 47
    • 0035064073 scopus 로고    scopus 로고
    • The bare lymphocyte syndrome and the regulation of MHC expression
    • Reith, W. & Mach, B. The bare lymphocyte syndrome and the regulation of MHC expression. Annu. Rev. Immunol. 19, 331-373 (2001).
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 331-373
    • Reith, W.1    Mach, B.2
  • 48
    • 0035379670 scopus 로고    scopus 로고
    • Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity
    • Nickerson, K. et al. Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity. J. Biol. Chem. 276, 19089-19093 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 19089-19093
    • Nickerson, K.1
  • 49
    • 0036777167 scopus 로고    scopus 로고
    • The Arabidopsis RRS1-R disease resistance gene - Uncovering the plant's nucleus as the new battlefield of plant defense?
    • Lahaye, T. The Arabidopsis RRS1-R disease resistance gene - uncovering the plant's nucleus as the new battlefield of plant defense? Trends Plant Sci. 7, 425-427 (2002).
    • (2002) Trends Plant Sci. , vol.7 , pp. 425-427
    • Lahaye, T.1
  • 50
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
    • Martinon, F., Burns, K. & Tschopp, J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol. Cell 10, 417-426 (2002).
    • (2002) Mol. Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 51
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou, H., Henzel, W. J., Liu, X., Lutschg, A. & Wang, X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-413 (1997). In this paper, the authors cloned and characterized APAF1, the first NOD protein to be identified in mammals.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 52
    • 0034708504 scopus 로고    scopus 로고
    • Expression and functional analysis of Apaf-1 isoforms. Extra WD-40 repeat is required for cytochrome-c binding and regulated activation of procaspase-9
    • Benedict, M. A., Hu, Y., Inohara, N & Nuñez, G. Expression and functional analysis of Apaf-1 isoforms. Extra WD-40 repeat is required for cytochrome-c binding and regulated activation of procaspase-9. J. Biol. Chem. 275, 8461-8468 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 8461-8468
    • Benedict, M.A.1    Hu, Y.2    Inohara, N.3    Nuñez, G.4
  • 53
    • 0033542482 scopus 로고    scopus 로고
    • Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
    • Qin, H. et al. Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature 399, 549-557 (1999).
    • (1999) Nature , vol.399 , pp. 549-557
    • Qin, H.1
  • 54
    • 0033580926 scopus 로고    scopus 로고
    • Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
    • Saleh, A. et al. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J. BioL Chem. 274, 17941-17945 (1999).
    • (1999) J. BioL Chem. , vol.274 , pp. 17941-17945
    • Saleh, A.1
  • 55
    • 0034623225 scopus 로고    scopus 로고
    • An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways
    • Inohara, N. et al. An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways. J. Biol. Chem. 275, 27823-27831 (2000). This paper provides a general model for activation of NOD-LRR proteins through NOD oligomerization and induced proximity of downstream effectors.
    • (2000) J. Biol. Chem. , vol.275 , pp. 27823-27831
    • Inohara, N.1
  • 56
    • 0035951792 scopus 로고    scopus 로고
    • Human Nod1 confers responsiveness to bacterial lipopolysaccharides
    • Inohara, N. et al. Human Nod1 confers responsiveness to bacterial lipopolysaccharides. J. Biol. Chem. 276, 2551-2554 (2001). The first evidence that NOD proteins recognize bacterial components.
    • (2001) J. Biol. Chem. , vol.276 , pp. 2551-2554
    • Inohara, N.1
  • 57
    • 17944380130 scopus 로고    scopus 로고
    • CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
    • Girardin, S. E. et al. CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri. EMBO Rep. 2, 736-742 (2001).
    • (2001) EMBO Rep. , vol.2 , pp. 736-742
    • Girardin, S.E.1
  • 58
    • 0037077283 scopus 로고    scopus 로고
    • The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
    • Srinivasula, S. M. et al. The PYRIN-CARD protein ASC is an activating adaptor for caspase-1. J. Biol. Chem. 277, 21119-21122 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 21119-21122
    • Srinivasula, S.M.1
  • 59
    • 0037470744 scopus 로고    scopus 로고
    • ASC is an activating adaptor for NF-κB and caspase-8-dependent apoptosis
    • Masumoto, J. et al. ASC is an activating adaptor for NF-κB and caspase-8-dependent apoptosis. Biochem. Biophys. Res. Commun. 303, 69-73 (2003).
    • (2003) Biochem. Biophys. Res. Commun. , vol.303 , pp. 69-73
    • Masumoto, J.1
  • 60
    • 0037075551 scopus 로고    scopus 로고
    • RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
    • Kobayashi, K. et al. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 416, 194-199 (2002).
    • (2002) Nature , vol.416 , pp. 194-199
    • Kobayashi, K.1
  • 61
    • 0033607768 scopus 로고    scopus 로고
    • ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
    • Masumoto, J. et al. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J. Biol. Chem. 274, 33835-33838 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 33835-33838
    • Masumoto, J.1
  • 62
    • 0036928158 scopus 로고    scopus 로고
    • Nod1, a CARD protein, enhances pro-interleukin-1β processing through the interaction with pro-caspase-1
    • Yoo, N. J. et al. Nod1, a CARD protein, enhances pro-interleukin-1β processing through the interaction with pro-caspase-1. Biochem. Biophys. Res. Commun. 299, 652-658 (2002).
    • (2002) Biochem. Biophys. Res. Commun. , vol.299 , pp. 652-658
    • Yoo, N.J.1
  • 63
    • 0035050491 scopus 로고    scopus 로고
    • Two distinct domains within CIITA mediate self-association: Involvement of the GTP-binding and leucine-rich repeat domains
    • Linhoff, M. W., Harton, J. A., Cressmann, D. E., Martin, B. K. & Ting, J. P. Two distinct domains within CIITA mediate self-association: involvement of the GTP-binding and leucine-rich repeat domains. Mol. Cell. Biol. 21, 3001-3011 (2001).
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3001-3011
    • Linhoff, M.W.1    Harton, J.A.2    Cressmann, D.E.3    Martin, B.K.4    Ting, J.P.5
  • 64
    • 0035943717 scopus 로고    scopus 로고
    • Self-association of class II transactivator correlates with its intracellular localization and transactivation
    • Kretsovali, A., Spilianakis, C., Dimakopoulos, A., Makatounakis, T. & Papamatheakis, J. Self-association of class II transactivator correlates with its intracellular localization and transactivation. J. Biol. Chem. 276, 32191-32197 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 32191-32197
    • Kretsovali, A.1    Spilianakis, C.2    Dimakopoulos, A.3    Makatounakis, T.4    Papamatheakis, J.5
  • 65
    • 0034960167 scopus 로고    scopus 로고
    • Self-association of CIITA and its transactivation potential
    • Sisk, T. J., Roys, S. & Chang, C. H. Self-association of CIITA and its transactivation potential. Mol. Cell. Biol. 21, 4919-4928 (2001).
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4919-4928
    • Sisk, T.J.1    Roys, S.2    Chang, C.H.3
  • 66
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura, Y. et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411, 603-606 (2001). This paper (together with reference 90) provides the first evidence that NOD2 mutations are associated with susceptibility to Crohn's disease. In addition, the paper provides the first evidence that disease variants are defective in the recognition of bacterial components.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1
  • 67
    • 0037221395 scopus 로고    scopus 로고
    • Crohn's disease-associated NOD 2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan
    • Bonen, D. K. et al. Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan. Gastroenterology 124, 140-146 (2003).
    • (2003) Gastroenterology , vol.124 , pp. 140-146
    • Bonen, D.K.1
  • 68
    • 0037458665 scopus 로고    scopus 로고
    • Host recognition of bacterial muramyl dipeptide mediated through NOD2: Implications for Crohn's disease
    • Inohara, N. et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2: implications for Crohn's disease. J. Biol. Chem 278, 5509-5512 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 5509-5512
    • Inohara, N.1
  • 69
    • 0012722659 scopus 로고    scopus 로고
    • Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
    • Girardin, S. E. et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J. Biol. Chem. 278, 8869-8872 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 8869-8872
    • Girardin, S.E.1
  • 70
    • 0032695108 scopus 로고    scopus 로고
    • Natural adjuvants: Endogenous activators of dendritic cells
    • Gallucci, S., Lolkema, M. & Matzinger, P. Natural adjuvants: endogenous activators of dendritic cells. Nature Med. 5, 1249-1255 (1999).
    • (1999) Nature Med. , vol.5 , pp. 1249-1255
    • Gallucci, S.1    Lolkema, M.2    Matzinger, P.3
  • 71
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger P. The danger model: a renewed sense of self. Science 296, 301-305 (2002).
    • (2002) Science , vol.296 , pp. 301-305
    • Matzinger, P.1
  • 72
    • 0033618630 scopus 로고    scopus 로고
    • Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2
    • Aliprantis, A. O., et al. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 285, 736-739 (1999).
    • (1999) Science , vol.285 , pp. 736-739
    • Aliprantis, A.O.1
  • 73
    • 0034601057 scopus 로고    scopus 로고
    • The apoptotic signaling pathway activated by Toll-iike receptor-2
    • Aliprantis, A. O., Yang, R. B., Weiss, D. S., Godowski, P. & Zychlinsky, A. The apoptotic signaling pathway activated by Toll-iike receptor-2. EMBO J. 19, 3325-3336 (2000).
    • (2000) EMBO J. , vol.19 , pp. 3325-3336
    • Aliprantis, A.O.1    Yang, R.B.2    Weiss, D.S.3    Godowski, P.4    Zychlinsky, A.5
  • 74
    • 0032404120 scopus 로고    scopus 로고
    • Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling
    • Balachandran, S. et al. Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling. EMBO J. 17, 6888-6902 (1998).
    • (1998) EMBO J. , vol.17 , pp. 6888-6902
    • Balachandran, S.1
  • 75
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi, A. & Dixit, V. M. Death receptors: signaling and modulation. Science 281, 1305-1308 (1998).
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 76
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-κB in preventing TNF-α-induced cell death
    • Beg, A. A. & Baltimore, D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science 274, 782-784 (1996).
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 77
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang, C. Y., Mayo, M, W., Korneluk, R. G., Goeddel, D. V. & Baldwin, A. S. Jr NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281, 1680-1683 (1998).
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin A.S., Jr.5
  • 79
    • 0037858060 scopus 로고    scopus 로고
    • Growth of the stress-bearing and shape-maintaining murein sacculus of Escherichia coli
    • Holtje, J. V. Growth of the stress-bearing and shape-maintaining murein sacculus of Escherichia coli. Microbiol. Mol. Biol. Rev. 62, 181-203 (1998).
    • (1998) Microbiol. Mol. Biol. Rev. , vol.62 , pp. 181-203
    • Holtje, J.V.1
  • 80
    • 0037022296 scopus 로고    scopus 로고
    • Human macrophage activation programs induced by bacterial pathogens
    • Nau, G. J. et al. Human macrophage activation programs induced by bacterial pathogens. Proc. Natl Acad. Sci. USA 99, 1503-1508 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 1503-1508
    • Nau, G.J.1
  • 82
    • 0034691601 scopus 로고    scopus 로고
    • Endotoxin and muramyl dipeptide modulate surface receptor expression on human mononuclear cells
    • Heinzelmann, M. et al. Endotoxin and muramyl dipeptide modulate surface receptor expression on human mononuclear cells. Immunopharmacology 48, 117-128 (2000).
    • (2000) Immunopharmacology , vol.48 , pp. 117-128
    • Heinzelmann, M.1
  • 83
    • 0035213770 scopus 로고    scopus 로고
    • Muramyl dipeptide-Lys stimulates the function of human dendritic cells
    • Todate, A. et al. Muramyl dipeptide-Lys stimulates the function of human dendritic cells. J. Leukocyte Biol. 70, 723-739 (2001).
    • (2001) J. Leukocyte Biol. , vol.70 , pp. 723-739
    • Todate, A.1
  • 84
    • 0036828844 scopus 로고    scopus 로고
    • Induction of NOD2 in myelomonocytic and intestinal epithelial cells via nuclear factor-κB activation
    • Gutierrez, O. et al. Induction of NOD2 in myelomonocytic and intestinal epithelial cells via nuclear factor-κB activation. J. Biol. Chem. 277, 41701-41705 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 41701-41705
    • Gutierrez, O.1
  • 85
    • 0035078190 scopus 로고    scopus 로고
    • Synergistic effect of muramyldipeptide with lipopolysaccharide of lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture
    • Yang, S. et al. Synergistic effect of muramyldipeptide with lipopolysaccharide of lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture. Infect. Immun. 69, 2045-2053 (2001).
    • (2001) Infect. Immun. , vol.69 , pp. 2045-2053
    • Yang, S.1
  • 86
    • 0018569936 scopus 로고
    • Enhancement of endotoxic shock by N-acetylmuramyl-L-alanyl-(L-seryl)-D-isoglutamine (muramyl dipeptide)
    • Ribi, E. E., Cantrell, J. L., Von Eschen, K. B. & Schwartzman, S. M. Enhancement of endotoxic shock by N-acetylmuramyl-L-alanyl-(L-seryl)-D-isoglutamine (muramyl dipeptide). Cancer Res. 39, 4756-4759 (1979).
    • (1979) Cancer Res. , vol.39 , pp. 4756-4759
    • Ribi, E.E.1    Cantrell, J.L.2    Von Eschen, K.B.3    Schwartzman, S.M.4
  • 87
    • 0037131232 scopus 로고    scopus 로고
    • The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan
    • Wolfert, M. A., Murray, T. F., Boons, G. J. & Moore, J. N. The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan. J. Biol. Chem. 277, 39179-39186 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 39179-39186
    • Wolfert, M.A.1    Murray, T.F.2    Boons, G.J.3    Moore, J.N.4
  • 88
    • 0033920567 scopus 로고    scopus 로고
    • Interactions between Listeria monocytogenes and host mammalian cells
    • Braun, L. & Cossart, P. Interactions between Listeria monocytogenes and host mammalian cells. Microbes Infect. 2, 803-811 (2000).
    • (2000) Microbes Infect. , vol.2 , pp. 803-811
    • Braun, L.1    Cossart, P.2
  • 89
    • 0035424169 scopus 로고    scopus 로고
    • Mutation in the class II transactivator leading to a mild immunodeficiency
    • Wiszniewski, W. et al. Mutation in the class II transactivator leading to a mild immunodeficiency J. Immunol. 167, 1787-1794 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 1787-1794
    • Wiszniewski, W.1
  • 90
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot, J. P. et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411,599-603 (2001).
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1
  • 91
    • 0035897904 scopus 로고    scopus 로고
    • Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
    • Hampe, J. et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 357, 1925-1928 (2001).
    • (2001) Lancet , vol.357 , pp. 1925-1928
    • Hampe, J.1
  • 92
    • 17944372335 scopus 로고    scopus 로고
    • CARD 15 mutations in Blau syndrome
    • Miceli-Richard, C. et al. CARD15 mutations in Blau syndrome. Nature Genet. 29, 19-20 (2001).
    • (2001) Nature Genet. , vol.29 , pp. 19-20
    • Miceli-Richard, C.1
  • 93
    • 0036846291 scopus 로고    scopus 로고
    • CARD15 mutations in familial granulomatosis syndromes: A study of the original Blau syndrome kindred and other families with large-vessel arteritis and cranial neuropathy
    • Wang, X. et al. CARD15 mutations in familial granulomatosis syndromes: a study of the original Blau syndrome kindred and other families with large-vessel arteritis and cranial neuropathy. Arthritis Rheum. 46, 3041-3045 (2002).
    • (2002) Arthritis Rheum. , vol.46 , pp. 3041-3045
    • Wang, X.1
  • 94
    • 0037452968 scopus 로고    scopus 로고
    • Gene/environment interaction modulated by allelic heterogeneity in inflammatory diseases
    • Chamaillard, M. et al. Gene/environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proc. Natl Acad. Sci. USA 100, 3455-3460 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 3455-3460
    • Chamaillard, M.1
  • 95
    • 18344385660 scopus 로고    scopus 로고
    • New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: A novel mutation underlies both syndromes
    • Dode, C. et al. New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes. Am. J. Hum Genet. 70, 498-506 (2002).
    • (2002) Am. J. Hum Genet. , vol.70 , pp. 498-506
    • Dode, C.1
  • 96
    • 0036302235 scopus 로고    scopus 로고
    • Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
    • Feldmann, J. et al. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. Am. J. Hum. Genet. 71, 198-203 (2002).
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 198-203
    • Feldmann, J.1
  • 97
    • 0036899758 scopus 로고    scopus 로고
    • De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin-associated autoinflammatory diseases
    • Aksentijevich, I. et al. De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum. 46, 3340-3348 (2002).
    • (2002) Arthritis Rheum. , vol.46 , pp. 3340-3348
    • Aksentijevich, I.1
  • 98
    • 0036745064 scopus 로고    scopus 로고
    • Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis
    • Aganna, E. et al. Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum. 46, 2445-2452 (2002).
    • (2002) Arthritis Rheum. , vol.46 , pp. 2445-2452
    • Aganna, E.1
  • 99
    • 0030745449 scopus 로고    scopus 로고
    • Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial mediterranean fever
    • The International FMF Consortium. Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial mediterranean fever. Cell 90, 797-807 (1997). The first evidence (together with reference 100) that pyrin mutations are associated with familial Mediterranean fever.
    • (1997) Cell , vol.90 , pp. 797-807
  • 100
    • 16944365196 scopus 로고    scopus 로고
    • A candidate gene for familial mediterranean fever
    • The French FMF Consortium. A candidate gene for familial mediterranean fever. Nature Genet. 17, 25-31 (1997).
    • (1997) Nature Genet. , vol.17 , pp. 25-31
  • 101
    • 0035914452 scopus 로고    scopus 로고
    • Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis
    • Richards, N. et al. Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis. J. Biol. Chem. 276, 39320-39329 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 39320-39329
    • Richards, N.1
  • 102
    • 0028797783 scopus 로고
    • Identification and characterization of a spinal muscular atrophy-determining gene
    • Lefebvre, S. et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell 80, 155-165 (1995).
    • (1995) Cell , vol.80 , pp. 155-165
    • Lefebvre, S.1
  • 103
    • 0033987669 scopus 로고    scopus 로고
    • A mouse model for spinal muscular atrophy
    • Hsieh-Li, H. M. et al. A mouse model for spinal muscular atrophy. Nature Genet. 24, 66-70 (2000).
    • (2000) Nature Genet. , vol.24 , pp. 66-70
    • Hsieh-Li, H.M.1
  • 104
    • 0032127922 scopus 로고    scopus 로고
    • Cloning and characterization of the multiple murine homologues of NAIP (neuronal apoptosis inhibitory protein)
    • Yaraghi, Z., Korneluk, R. G. & MacKenzie, A. Cloning and characterization of the multiple murine homologues of NAIP (neuronal apoptosis inhibitory protein). Genomics 51, 107-113 (1998).
    • (1998) Genomics , vol.51 , pp. 107-113
    • Yaraghi, Z.1    Korneluk, R.G.2    MacKenzie, A.3
  • 105
    • 0031231588 scopus 로고    scopus 로고
    • Genetic and physical mapping of the mouse host resistance locus Lgn1
    • Diez, E. et al. Genetic and physical mapping of the mouse host resistance locus Lgn1. Mamm. Genome 8, 682-685 (1997).
    • (1997) Mamm. Genome , vol.8 , pp. 682-685
    • Diez, E.1
  • 106
    • 0032886552 scopus 로고    scopus 로고
    • The mouse Naip gene cluster on chromosome 13 encodes several distinct functional transcripts
    • Scharf, J. M. et al. The mouse Naip gene cluster on chromosome 13 encodes several distinct functional transcripts. Mamm. Genome 10, 1032-1035 (1999).
    • (1999) Mamm. Genome , vol.10 , pp. 1032-1035
    • Scharf, J.M.1
  • 107
    • 0029347004 scopus 로고
    • Natural resistance to infection with Legionella pneumophila: Chromosomal localization of the Lgn1 susceptibility gene
    • Beckers, M. C., Yoshida, S., Morgan, K., Skamene, E. & Gros, P. Natural resistance to infection with Legionella pneumophila: chromosomal localization of the Lgn1 susceptibility gene. Mamm. Genome 6, 540-545 (1995).
    • (1995) Mamm. Genome , vol.6 , pp. 540-545
    • Beckers, M.C.1    Yoshida, S.2    Morgan, K.3    Skamene, E.4    Gros, P.5
  • 108
    • 0029004042 scopus 로고
    • Lgn1, a gene that determines susceptibility to Legionella pneumophila, maps to mouse chromosome 13
    • Dietrich, W. F., Damron, D. M., Isberg, R. R., Lander, E. S. & Swanson, M. S. Lgn1, a gene that determines susceptibility to Legionella pneumophila, maps to mouse chromosome 13. Genomics 26, 443-450 (1995).
    • (1995) Genomics , vol.26 , pp. 443-450
    • Dietrich, W.F.1    Damron, D.M.2    Isberg, R.R.3    Lander, E.S.4    Swanson, M.S.5
  • 109
    • 0037425584 scopus 로고    scopus 로고
    • Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila
    • Wright, E. K. et al. Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila. Curr. Biol. 13, 27-36 (2003).
    • (2003) Curr. Biol. , vol.13 , pp. 27-36
    • Wright, E.K.1
  • 110
    • 0037228017 scopus 로고    scopus 로고
    • Birc 1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila
    • Diez, E. et al. Birc 1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nature Genet. 33, 55-60 (2003).
    • (2003) Nature Genet. , vol.33 , pp. 55-60
    • Diez, E.1
  • 111
    • 0035887426 scopus 로고    scopus 로고
    • Legionella pneumophila is internalized by a macropinocytotic uptake pathway controlled by the Dot/Icm system and the mouse Lgn1 locus
    • Watarai, M. et al. Legionella pneumophila is internalized by a macropinocytotic uptake pathway controlled by the Dot/Icm system and the mouse Lgn1 locus. J. Exp. Med. 194, 1081-1096 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 1081-1096
    • Watarai, M.1
  • 113
    • 0037144586 scopus 로고    scopus 로고
    • A novel PAAD-containing protein that modulates NF-κB induction by cytokines tumor necrosis factor-α and interleukin-1β
    • Fiorentino, L. et al. A novel PAAD-containing protein that modulates NF-κB induction by cytokines tumor necrosis factor-α and interleukin-1β. J. Biol. Chem. 277, 35333-35340 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 35333-35340
    • Fiorentino, L.1
  • 114
    • 0034142264 scopus 로고    scopus 로고
    • The neuronal apoptosis inhibitory protein (Naip) is expressed in macrophages and is modulated after phagocytosis and during intracellular infection with Legionella pneumophila
    • Diez, E., Yaraghi, Z., MacKenzie, A. & Gros, P. The neuronal apoptosis inhibitory protein (Naip) is expressed in macrophages and is modulated after phagocytosis and during intracellular infection with Legionella pneumophila. J. Immunol. 184, 1470-1477 (2000).
    • (2000) J. Immunol. , vol.184 , pp. 1470-1477
    • Diez, E.1    Yaraghi, Z.2    MacKenzie, A.3    Gros, P.4


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