CRISPR/Cas9 in Genome Editing and beyond

Annual Review of Biochemistry

Volumn 85, Issue , 2016, Pages 227-264

  Wang, Haifeng ^a   La Russa, Marie ^a,b   Qi, Lei S ^a,c  

^a Stanford University   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

Cas9 structure; CRISPR applications; DCas9; Epigenetic regulation; Gene regulation; Genomic imaging

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9; DEOXYRIBONUCLEASE; DNA; ENDONUCLEASE; GUIDE RNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES;

ADAPTIVE IMMUNITY; ARCHAEON; ARTICLE; BACTERIUM; BASE PAIRING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRISPR CAS SYSTEM; CRISPR CAS9 SYSTEM; DNA CLEAVAGE; DNA REPAIR; EPIGENETICS; GENE CONTROL; GENE FUNCTION; GENE LOCUS; GENE SEQUENCE; GENE TARGETING; GENE THERAPY; GENETIC DISORDER; GENETIC ENGINEERING; GENETIC VARIABILITY; GENOME; GENOME EDITING; HUMAN; INFECTION; MALIGNANT NEOPLASTIC DISEASE; MEDICAL RESEARCH; MOLECULAR IMAGING; NONHUMAN; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN STRUCTURE; REVERSE GENETICS; RNA BINDING; GENE EDITING; GENETIC EPIGENESIS; GENETICS; HUMAN GENOME; METABOLISM; PROCEDURES; PROTEIN ENGINEERING; PROTEIN SECONDARY STRUCTURE;

BACTERIAL PROTEINS; BASE PAIRING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; DNA CLEAVAGE; DNA REPAIR; ENDONUCLEASES; EPIGENESIS, GENETIC; GENE EDITING; GENE TARGETING; GENOME, HUMAN; HUMANS; MOLECULAR IMAGING; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; RNA, GUIDE;

EID: 84974717567     PISSN: 00664154     EISSN: 15454509     Source Type: Book Series    
DOI: 10.1146/annurev-biochem-060815-014607     Document Type: Article

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