Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

Genome Research

Volumn 25, Issue 8, 2015, Pages 1158-1169

  Polstein, Lauren R ^a   Perez Pinera, Pablo ^a,c   Kocak, D Dewran ^a   Vockley, Christopher M ^b   Bledsoe, Peggy ^b   Song, Lingyun ^b   Safi, Alexias ^b   Crawford, Gregory E ^b   Reddy, Timothy E ^b   Gersbach, Charles A ^a,b  

^a Duke University   (United States)

^b DUKE UNIVERSITY   (United States)

^c University of Illinois at Urbana Champaign   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; DEOXYRIBONUCLEASE; DNA; RNA; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; TRANSCRIPTOME; CHROMATIN; DNA BINDING PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DNA BINDING; GENE ACTIVATION; GENE CONTROL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RNA SEQUENCE; TRANSCRIPTOMICS; BINDING SITE; CHEMISTRY; CHROMATIN; CRISPR CAS SYSTEM; DNA SEQUENCE; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HEK293 CELL LINE; HUMAN GENOME; METABOLISM; PROCEDURES; SEQUENCE ANALYSIS;

BINDING SITES; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CRISPR-CAS SYSTEMS; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GENOME, HUMAN; HEK293 CELLS; HUMANS; SEQUENCE ANALYSIS, DNA; SEQUENCE ANALYSIS, RNA; TRANSCRIPTION FACTORS;

EID: 84938857368     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.179044.114     Document Type: Article

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