Locus-specific editing of histone modifications at endogenous enhancers

Nature Biotechnology

Volumn 31, Issue 12, 2013, Pages 1133-1136

  Mendenhall, Eric M ^a,b,c,e   Williamson, Kaylyn E ^a,b,c   Reyon, Deepak ^b   Zou, James Y ^a,b,c,d   Ram, Oren ^a,b,c   Joung, J Keith ^b   Bernstein, Bradley E ^a,b,c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d HARVARD UNIVERSITY   (United States)

^e UNIVERSITY OF ALABAMA IN HUNTSVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATIN MODIFICATION; DOWN-REGULATION; FUNCTIONAL GENOMICS; HISTONE MODIFICATION; REGULATORY ELEMENTS; SEQUENCE VARIANTS; TISSUE SPECIFICS; TRANSCRIPTIONAL ACTIVITY;

GENES; MAMMALS;

TRANSCRIPTION;

HISTONE DEMETHYLASE; MESSENGER RNA;

ANTIGEN BINDING; ARTICLE; CELL TYPE; CHROMATIN; CONTROLLED STUDY; DEMETHYLATION; DOWN REGULATION; ENHANCER REGION; ERYTHROLEUKEMIA CELL; FUNCTIONAL GENOMICS; GENE LOCUS; GENE MAPPING; GENE TARGETING; GENETIC ASSOCIATION; GENETIC MANIPULATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE;

CHROMATIN; ENHANCER ELEMENTS, GENETIC; HISTONES; MUTAGENESIS, SITE-DIRECTED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; REGULATORY ELEMENTS, TRANSCRIPTIONAL;

EID: 84886084801     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2701     Document Type: Article

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