메뉴 건너뛰기




Volumn 22, Issue 24, 2003, Pages 6631-6641

Visualizing telomere dynamics in living mammalian cells using PNA probes

Author keywords

ALT; Live cell imaging; PML; PNA; Telomeres

Indexed keywords

DNA; FLUORESCENT DYE; GLASS;

EID: 0346993718     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg633     Document Type: Article
Times cited : (171)

References (52)
  • 1
    • 0031009827 scopus 로고    scopus 로고
    • Chromatin dynamics in interphase nuclei and its implications for nuclear structure
    • Abney, J.R., Cutler, B., Fillbach, M.L., Axelrod, D. and Scalettar, B.A. (1997) Chromatin dynamics in interphase nuclei and its implications for nuclear structure. J. Cell Biol., 137, 1459-1468.
    • (1997) J. Cell Biol. , vol.137 , pp. 1459-1468
    • Abney, J.R.1    Cutler, B.2    Fillbach, M.L.3    Axelrod, D.4    Scalettar, B.A.5
  • 2
    • 0034994404 scopus 로고    scopus 로고
    • Human interchromosomal telomeric-like repeats: Sequence organization and mechanisms of origin
    • Azzalin, C.M., Nergadze, S.G. and Giulotto, E. (2001) Human interchromosomal telomeric-like repeats: sequence organization and mechanisms of origin. Chromosoma, 110, 75-82.
    • (2001) Chromosoma , vol.110 , pp. 75-82
    • Azzalin, C.M.1    Nergadze, S.G.2    Giulotto, E.3
  • 3
    • 0035874977 scopus 로고    scopus 로고
    • Telomere position effect in human cells
    • Baur, J.A., Zou, Y., Shay, J.W. and Wright, W.E. (2001) Telomere position effect in human cells. Science, 292, 2075-2077.
    • (2001) Science , vol.292 , pp. 2075-2077
    • Baur, J.A.1    Zou, Y.2    Shay, J.W.3    Wright, W.E.4
  • 4
    • 0032750068 scopus 로고    scopus 로고
    • Quantitative motion analysis of subchromosomal foci in living cells using four-dimensional microscopy
    • Bornfleth, H., Edelmann, P., Zink, D., Cremer, T. and Cremer, C. (1999) Quantitative motion analysis of subchromosomal foci in living cells using four-dimensional microscopy. Biophys. J., 77, 2871-2886.
    • (1999) Biophys. J. , vol.77 , pp. 2871-2886
    • Bornfleth, H.1    Edelmann, P.2    Zink, D.3    Cremer, T.4    Cremer, C.5
  • 5
    • 0033083793 scopus 로고    scopus 로고
    • Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division
    • Brown, K.E., Baxter, J., Graf, D., Merkenschlager, M. and Fisher, A.G. (1999) Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Mol. Cell, 3, 207-217.
    • (1999) Mol. Cell , vol.3 , pp. 207-217
    • Brown, K.E.1    Baxter, J.2    Graf, D.3    Merkenschlager, M.4    Fisher, A.G.5
  • 7
    • 0036006293 scopus 로고    scopus 로고
    • Chromatin motion is constrained by association with nuclear compartments in human cells
    • Chubb, JR., Boyle, S., Perry, P. and Bickmore, W.A. (2002) Chromatin motion is constrained by association with nuclear compartments in human cells. Curr. Biol., 12, 439-445.
    • (2002) Curr. Biol. , vol.12 , pp. 439-445
    • Chubb, J.R.1    Boyle, S.2    Perry, P.3    Bickmore, W.A.4
  • 8
    • 0035160043 scopus 로고    scopus 로고
    • Termini of human chromosomes display elevated rates of mitotic recombination
    • Comforth, M.N. and Eberle, R.L. (2001) Termini of human chromosomes display elevated rates of mitotic recombination. Mutagenesis, 16, 85-89.
    • (2001) Mutagenesis , vol.16 , pp. 85-89
    • Comforth, M.N.1    Eberle, R.L.2
  • 9
    • 0033169026 scopus 로고    scopus 로고
    • Silencing at Drosophila telomeres: Nuclear organization and chromatin structure play critical roles
    • Cryderman, D.E., Morris, E.J., Biessmann, H., Elgin, S.C.R. and Wallrath, L.L. (1999) Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles. EMBO J., 18, 3724-3735.
    • (1999) EMBO J. , vol.18 , pp. 3724-3735
    • Cryderman, D.E.1    Morris, E.J.2    Biessmann, H.3    Elgin, S.C.R.4    Wallrath, L.L.5
  • 10
    • 0026541384 scopus 로고
    • Human telomeres are attached to the nuclear matrix
    • de Lange, T. (1992) Human telomeres are attached to the nuclear matrix. EMBO J., 11, 717-724.
    • (1992) EMBO J. , vol.11 , pp. 717-724
    • De Lange, T.1
  • 11
    • 0032127323 scopus 로고    scopus 로고
    • Assesment of telomeric length in hematopoietic interphase cells using in situ hybridization and digital fluorescence microscopy
    • de Pauw, E.S.D., Verwoerd, N.P., Duinkerken, N., Willemze, R., Raap, A.K., Fibbe, W.E. and Tanke, H.J. (1998) Assesment of telomeric length in hematopoietic interphase cells using in situ hybridization and digital fluorescence microscopy. Cytometry, 32, 163-169.
    • (1998) Cytometry , vol.32 , pp. 163-169
    • De Pauw, E.S.D.1    Verwoerd, N.P.2    Duinkerken, N.3    Willemze, R.4    Raap, A.K.5    Fibbe, W.E.6    Tanke, H.J.7
  • 13
    • 0036566036 scopus 로고    scopus 로고
    • Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres
    • Espejel, S., Franco, S., Rodriguez-Perales, S., Bouffler, S.D., Cigudosa, J.C. and Blasco, M.A. (2002) Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres. EMBO J., 21, 2207-2219.
    • (2002) EMBO J. , vol.21 , pp. 2207-2219
    • Espejel, S.1    Franco, S.2    Rodriguez-Perales, S.3    Bouffler, S.D.4    Cigudosa, J.C.5    Blasco, M.A.6
  • 14
    • 0026759324 scopus 로고
    • Cell cycle dependent chromosomal movement in pre-mitotic human T-lymphocyte nuclei
    • Ferguson, M. and Ward, DC. (1992) Cell cycle dependent chromosomal movement in pre-mitotic human T-lymphocyte nuclei. Chromosoma, 101, 557-565.
    • (1992) Chromosoma , vol.101 , pp. 557-565
    • Ferguson, M.1    Ward, D.C.2
  • 15
    • 0037083982 scopus 로고    scopus 로고
    • A central role for Plasmodium falciparum subtelomeric regions in spatial positioning and telomere length regulation
    • Figueiredo, L.M., Freitas-Junior, L.H., Bottius, E., Olivo-Marin, J.-C. and Scherf, A. (2002) A central role for Plasmodium falciparum subtelomeric regions in spatial positioning and telomere length regulation. EMBO J., 21, 815-824.
    • (2002) EMBO J. , vol.21 , pp. 815-824
    • Figueiredo, L.M.1    Freitas-Junior, L.H.2    Bottius, E.3    Olivo-Marin, J.-C.4    Scherf, A.5
  • 16
    • 0027181381 scopus 로고
    • Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells
    • Fisher, T.L., Terhorst, T., Cao, X. and Wagner, R.W. (1993) Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells. Nucleic Acids Res., 21, 3857-3865.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 3857-3865
    • Fisher, T.L.1    Terhorst, T.2    Cao, X.3    Wagner, R.W.4
  • 17
    • 0028798545 scopus 로고
    • The detection of subtelomeric chromosomal rearrangements in idiopathic mental retardation
    • Flint, J., Wilkie, A., Buckle, V., Winter, R., Holland, A. and McDermid, H. (1995) The detection of subtelomeric chromosomal rearrangements in idiopathic mental retardation. Nat. Genet., 9, 132-139.
    • (1995) Nat. Genet. , vol.9 , pp. 132-139
    • Flint, J.1    Wilkie, A.2    Buckle, V.3    Winter, R.4    Holland, A.5    McDermid, H.6
  • 19
    • 0029820640 scopus 로고    scopus 로고
    • The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae
    • Gotta, M., Laroche, T., Formenton, A., Maillet, L., Scherthan, H. and Gasser, S.M. (1996) The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae. J. Cell Biol., 134, 1349-1363.
    • (1996) J. Cell Biol. , vol.134 , pp. 1349-1363
    • Gotta, M.1    Laroche, T.2    Formenton, A.3    Maillet, L.4    Scherthan, H.5    Gasser, S.M.6
  • 20
    • 0025201982 scopus 로고
    • Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
    • Gottschling, D.E., Aparicio, O.M., Billington, B.L. and Zakian, V.A. (1990) Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell, 63, 751-762.
    • (1990) Cell , vol.63 , pp. 751-762
    • Gottschling, D.E.1    Aparicio, O.M.2    Billington, B.L.3    Zakian, V.A.4
  • 21
    • 0037164718 scopus 로고    scopus 로고
    • Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast
    • Hediger, F., Neumann, F.R., Van Houwe, G., Dubrana, K. and Gasser, S.M. (2002) Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast. Curr. Biol., 12, 2076-2089.
    • (2002) Curr. Biol. , vol.12 , pp. 2076-2089
    • Hediger, F.1    Neumann, F.R.2    Van Houwe, G.3    Dubrana, K.4    Gasser, S.M.5
  • 22
    • 0030006735 scopus 로고    scopus 로고
    • In situ analysis of changes in telomere size during replicative aging and cell transformation
    • Henderson, S., Allsopp, R., Spector, D.L., Wang, S. S. and Harley, C. (1996) In situ analysis of changes in telomere size during replicative aging and cell transformation. J. Cell Biol., 134, 1-12.
    • (1996) J. Cell Biol. , vol.134 , pp. 1-12
    • Henderson, S.1    Allsopp, R.2    Spector, D.L.3    Wang, S.S.4    Harley, C.5
  • 23
    • 0037148281 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres in mammalian cells
    • Henson, J.D., Neuman, A.A., Yeager, T.R. and Reddel, R.R. (2002) Alternative lengthening of telomeres in mammalian cells. Oncogene, 21, 598-610.
    • (2002) Oncogene , vol.21 , pp. 598-610
    • Henson, J.D.1    Neuman, A.A.2    Yeager, T.R.3    Reddel, R.R.4
  • 24
    • 0035824395 scopus 로고    scopus 로고
    • Chromosome dynamics in the yeast interphase nucleus
    • Heun, P., Laroche, T., Shimada, K., Furrer, P. and Gasser, S.M. (2001) Chromosome dynamics in the yeast interphase nucleus. Science, 294, 2181-2186.
    • (2001) Science , vol.294 , pp. 2181-2186
    • Heun, P.1    Laroche, T.2    Shimada, K.3    Furrer, P.4    Gasser, S.M.5
  • 25
    • 0034669104 scopus 로고    scopus 로고
    • Ku acts in a unique way at the mammalian telomere to prevent end joining
    • Hsu, H.-L. et al. (2000) Ku acts in a unique way at the mammalian telomere to prevent end joining. Genes Dev., 14, 2807-2812.
    • (2000) Genes Dev. , vol.14 , pp. 2807-2812
    • Hsu, H.-L.1
  • 26
    • 0036867444 scopus 로고    scopus 로고
    • Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity
    • Koering, C.E. et al. (2002) Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity. EMBO Rep., 3, 1055-1061.
    • (2002) EMBO Rep. , vol.3 , pp. 1055-1061
    • Koering, C.E.1
  • 29
    • 0029827128 scopus 로고    scopus 로고
    • Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex
    • Ludérus, M.E.E., van Steensel, B., Chong, L., Sibon, O.C.M., Cremers, F.F.M. and de Lange, T. (1996) Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex. J. Cell Biol., 135, 867-881.
    • (1996) J. Cell Biol. , vol.135 , pp. 867-881
    • Ludérus, M.E.E.1    Van Steensel, B.2    Chong, L.3    Sibon, O.C.M.4    Cremers, F.F.M.5    De Lange, T.6
  • 30
    • 0035875667 scopus 로고    scopus 로고
    • Specific targeting of insect and vertebrate telomeres with pyrrole and imidazole polyamides
    • Maeshima, K., Janssen, S. and Laemmli, U.K. (2001) Specific targeting of insect and vertebrate telomeres with pyrrole and imidazole polyamides. EMBO J., 20, 3218-3228.
    • (2001) EMBO J. , vol.20 , pp. 3218-3228
    • Maeshima, K.1    Janssen, S.2    Laemmli, U.K.3
  • 31
    • 0037049548 scopus 로고    scopus 로고
    • Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH
    • Mahy, N.L., Perry, P.E. and Bickmore, W.A. (2002) Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH. J. Cell Biol., 159, 753-763.
    • (2002) J. Cell Biol. , vol.159 , pp. 753-763
    • Mahy, N.L.1    Perry, P.E.2    Bickmore, W.A.3
  • 33
    • 0023856424 scopus 로고
    • Glass beads load macromolecules into living cells
    • McNeil, P.L. and Werder, E. (1987) Glass beads load macromolecules into living cells. J. Cell Sci., 88, 669-678.
    • (1987) J. Cell Sci. , vol.88 , pp. 669-678
    • McNeil, P.L.1    Werder, E.2
  • 35
    • 0035130130 scopus 로고    scopus 로고
    • Telomere associations in interphase nuclei: Possible role in maintenance of interphase chromosome topology
    • Nagele, R.G., Velasco, A.Q., Anderson, W.J., McMahon, D.J., Thomson, Z., Fazekas, J., Wind, K. and Lee, H. (2001) Telomere associations in interphase nuclei: possible role in maintenance of interphase chromosome topology. J. Cell Sci., 114, 377-388.
    • (2001) J. Cell Sci. , vol.114 , pp. 377-388
    • Nagele, R.G.1    Velasco, A.Q.2    Anderson, W.J.3    McMahon, D.J.4    Thomson, Z.5    Fazekas, J.6    Wind, K.7    Lee, H.8
  • 36
    • 0027965291 scopus 로고
    • Telomere-associated chromosome breakage in fission yeast results in variegated expression of adjacent genes
    • Nimmo, E.R., Cranston, G. and Allshire R.C. (1994) Telomere-associated chromosome breakage in fission yeast results in variegated expression of adjacent genes. EMBO J., 13, 3801-3811.
    • (1994) EMBO J. , vol.13 , pp. 3801-3811
    • Nimmo, E.R.1    Cranston, G.2    Allshire, R.C.3
  • 38
    • 0027197103 scopus 로고
    • Lateral diffusion in an archipelago: Single-particle diffusion
    • Saxton, M.J. (1993) Lateral diffusion in an archipelago: single-particle diffusion. Biophys. J., 64, 1766-1780.
    • (1993) Biophys. J. , vol.64 , pp. 1766-1780
    • Saxton, M.J.1
  • 39
    • 0035963271 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas
    • Scheel, S. et al. (2001) Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas. Oncogene. 20, 3835-3844.
    • (2001) Oncogene , vol.20 , pp. 3835-3844
    • Scheel, S.1
  • 40
    • 0029829004 scopus 로고    scopus 로고
    • Dynamic elastic behavior of α-satellite DNA domains visualized in situ in living human cells
    • Shelby, R.D., Hahn, K.M. and Sullivan, K.F. (1996) Dynamic elastic behavior of α-satellite DNA domains visualized in situ in living human cells. J. Cell Biol., 135, 545-557.
    • (1996) J. Cell Biol. , vol.135 , pp. 545-557
    • Shelby, R.D.1    Hahn, K.M.2    Sullivan, K.F.3
  • 41
    • 0034735515 scopus 로고    scopus 로고
    • Mutational analysis of fibrillarin and its mobility in living human cells
    • Snaar, S., Wiesmeijer, K., Jochemsen, A.G., Tanke, H.J. and Dirks, R.W. (2000) Mutational analysis of fibrillarin and its mobility in living human cells. J. Cell Biol., 151, 653-662.
    • (2000) J. Cell Biol. , vol.151 , pp. 653-662
    • Snaar, S.1    Wiesmeijer, K.2    Jochemsen, A.G.3    Tanke, H.J.4    Dirks, R.W.5
  • 43
    • 0035150980 scopus 로고    scopus 로고
    • Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator
    • Tumbar, T. and Belmont, A.S. (2001) Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator. Nat. Cell Biol., 3, 134-139.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 134-139
    • Tumbar, T.1    Belmont, A.S.2
  • 46
    • 0035928736 scopus 로고    scopus 로고
    • Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus
    • Vazquez, J., Belmont, A.S. and Sedat, J.W. (2001) Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr. Biol., 11, 1227-1239.
    • (2001) Curr. Biol. , vol.11 , pp. 1227-1239
    • Vazquez, J.1    Belmont, A.S.2    Sedat, J.W.3
  • 48
    • 0036966365 scopus 로고    scopus 로고
    • Mobile foci of Sp100 do not contain PML: PML bodies are immobile but PML and Sp100 proteins are not
    • Wiesmeijer, K., Molenaar, C., Bekeer, I.M.L.A., Tanke, H.J. and Dirks, R.W. (2002) Mobile foci of Sp100 do not contain PML: PML bodies are immobile but PML and Sp100 proteins are not. J. Struct. Biol., 140, 180-188.
    • (2002) J. Struct. Biol. , vol.140 , pp. 180-188
    • Wiesmeijer, K.1    Molenaar, C.2    Bekeer, I.M.L.A.3    Tanke, H.J.4    Dirks, R.W.5
  • 49
    • 0034730633 scopus 로고    scopus 로고
    • NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells
    • Wu, G., Lee, W.-H., and Chen, P.-L. (2000) NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. J. Biol. Chem., 275, 30618-30622.
    • (2000) J. Biol. Chem. , vol.275 , pp. 30618-30622
    • Wu, G.1    Lee, W.-H.2    Chen, P.-L.3
  • 50
    • 0037843426 scopus 로고    scopus 로고
    • Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen breakage syndrome 1
    • Wu, G., Jiang, X., Lee, W.-H. and Chen, P.-L. (2003) Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen breakage syndrome 1. Cancer Res., 63, 2589-2595.
    • (2003) Cancer Res. , vol.63 , pp. 2589-2595
    • Wu, G.1    Jiang, X.2    Lee, W.-H.3    Chen, P.-L.4
  • 51
    • 0033199695 scopus 로고    scopus 로고
    • Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body
    • Yeager, T.R., Neumann, A.A., Englezou, A., Huschtscha, L.I., Noble, J.R. and Reddel, R.R. (1999) Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res., 59, 4175-4179.
    • (1999) Cancer Res. , vol.59 , pp. 4175-4179
    • Yeager, T.R.1    Neumann, A.A.2    Englezou, A.3    Huschtscha, L.I.4    Noble, J.R.5    Reddel, R.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.