Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells

Cell Research

Volumn 25, Issue 1, 2015, Pages 67-79

  Wu, Yuxuan ^a,b   Zhou, Hai ^a,b,c   Fan, Xiaoying ^d   Zhang, Ying ^b,e   Zhang, Man ^a,b   Wang, Yinghua ^a,b   Xie, Zhenfei ^a,b   Bai, Meizhu ^a,b,f   Yin, Qi ^a,b   Liang, Dan ^a,b   Tang, Wei ^a   Liao, Jiaoyang ^a,b   Zhou, Chikai ^a,b   Liu, Wujuan ^a,b   Zhu, Ping ^d   Guo, Hongshan ^d   Pan, Hong ^a,b   Wu, Chunlian ^c   Shi, Huijuan ^g   Wu, Ligang ^b,e   Tang, Fuchou ^d   Li, Jinsong ^a,b,f   more..

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^c CHINA WEST NORMAL UNIVERSITY   (China)

^d PEKING UNIVERSITY   (China)

^e INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^f SHANGHAITECH UNIVERSITY   (China)

^g SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RESEARCH   (China)

Author keywords

CRISPR Cas9; Gene therapy; Spermatogonial stem cell

Indexed keywords

GAMMA CRYSTALLIN; GAMMAC-CRYSTALLIN PROTEIN, MOUSE;

ADULT STEM CELL; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CRISPR CAS SYSTEM; DNA END JOINING REPAIR; FEMALE; GENE THERAPY; GENETICS; INFERTILITY, MALE; MALE; METABOLISM; MOUSE; MUTAGENESIS; PROTO ONCOGENE; SPERMATOGENESIS; TRANSGENE; TRANSPLANTATION;

ADULT STEM CELLS; ANIMALS; CELLS, CULTURED; CRISPR-CAS SYSTEMS; DNA END-JOINING REPAIR; FEMALE; GAMMA-CRYSTALLINS; GENES, ERBB-1; GENETIC THERAPY; INFERTILITY, MALE; MALE; MICE; MICE, INBRED BALB C; MUTAGENESIS; SPERMATOGENESIS; TRANSGENES;

EID: 84920269807     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2014.160     Document Type: Article

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