A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

Nature Chemical Biology

Volumn 11, Issue 3, 2015, Pages 198-200

  Polstein, Lauren R ^a   Gersbach, Charles A ^a,b,c  

^a USA   (United States)

^b DUKE UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; CIB1 PROTEIN; CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9; CRYPTOCHROME 2; HETERODIMER; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MASH1; UNCLASSIFIED DRUG; VEGETABLE PROTEIN; CRY2 PROTEIN, HUMAN; CRYPTOCHROME; DNA; RNA;

AMINO TERMINAL SEQUENCE; ARABIDOPSIS THALIANA; ARTICLE; BLUE LIGHT; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRISPR CAS SYSTEM; DNA SEQUENCE; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; LIGHT ACTIVATED CRISPR CAS9 EFFECTOR SYSTEM; NONHUMAN; OPTOGENETICS; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; BIOSYNTHESIS; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; LIGHT; PLASMID; PROTEIN ENGINEERING; RADIATION RESPONSE; STREPTOCOCCUS PYOGENES; TRANSCRIPTION INITIATION;

CRISPR-CAS SYSTEMS; CRYPTOCHROMES; DNA; GENE EXPRESSION REGULATION; HUMANS; LIGHT; OPTOGENETICS; PLASMIDS; PROTEIN ENGINEERING; RNA; STREPTOCOCCUS PYOGENES; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84925534357     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1753     Document Type: Article

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