메뉴 건너뛰기




Volumn 527, Issue 7576, 2015, Pages 110-113

Conformational control of DNA target cleavage by CRISPR-Cas9

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; NUCLEASE; BACTERIAL PROTEIN; CRISPR ASSOCIATED PROTEIN; DNA; ENDONUCLEASE; GUIDE RNA;

EID: 84946215320     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature15544     Document Type: Article
Times cited : (474)

References (31)
  • 2
    • 84899134190 scopus 로고    scopus 로고
    • CRISPR-Cas systems: Prokaryotes upgrade to adaptive immunity
    • Barrangou, R. & Marraffini, L. A. CRISPR-Cas systems: prokaryotes upgrade to adaptive immunity. Mol. Cell 54, 234-244 (2014).
    • (2014) Mol. Cell , vol.54 , pp. 234-244
    • Barrangou, R.1    Marraffini, L.A.2
  • 3
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • Jinek, M. et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816-821 (2012).
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1
  • 4
    • 84902096048 scopus 로고    scopus 로고
    • Development and applications of CRISPR-Cas9 for genome engineering
    • Hsu, P. D., Lander, E. S. & Zhang, F. Development and applications of CRISPR-Cas9 for genome engineering. Cell 157, 1262-1278 (2014).
    • (2014) Cell , vol.157 , pp. 1262-1278
    • Hsu, P.D.1    Lander, E.S.2    Zhang, F.3
  • 5
    • 84913594397 scopus 로고    scopus 로고
    • Genome editing. The new frontier of genome engineering with CRISPR-Cas9
    • Doudna, J. A. & Charpentier, E. Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science 346, 1258096 (2014).
    • (2014) Science , vol.346 , pp. 1258096
    • Doudna, J.A.1    Charpentier, E.2
  • 6
    • 84929666410 scopus 로고    scopus 로고
    • Expanding the biologist's toolkit with CRISPR-Cas9
    • Sternberg, S. H. & Doudna, J. A. Expanding the biologist's toolkit with CRISPR-Cas9. Mol. Cell 58, 568-574 (2015).
    • (2015) Mol. Cell , vol.58 , pp. 568-574
    • Sternberg, S.H.1    Doudna, J.A.2
  • 7
    • 84911465571 scopus 로고    scopus 로고
    • Target specificity of the CRISPR-Cas9 system
    • Wu, X., Kriz, A. J. & Sharp, P. A. Target specificity of the CRISPR-Cas9 system. Quant. Biol. 2, 59-70 (2014).
    • (2014) Quant. Biol. , vol.2 , pp. 59-70
    • Wu, X.1    Kriz, A.J.2    Sharp, P.A.3
  • 8
    • 84937569497 scopus 로고    scopus 로고
    • Delivery and specificity of CRISPR-Cas9 genome editing technologies for human gene therapy
    • Gori, J. L. et al. Delivery and specificity of CRISPR-Cas9 genome editing technologies for human gene therapy. Hum. Gene Ther. 26, 443-451 (2015).
    • (2015) Hum. Gene Ther. , vol.26 , pp. 443-451
    • Gori, J.L.1
  • 9
    • 84902095352 scopus 로고    scopus 로고
    • Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
    • Wu, X. et al. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnol. 32, 670-676 (2014).
    • (2014) Nature Biotechnol. , vol.32 , pp. 670-676
    • Wu, X.1
  • 10
    • 84923266604 scopus 로고    scopus 로고
    • GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
    • Tsai, S. Q. et al. GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases. Nature Biotechnol. 33, 187-197 (2015).
    • (2015) Nature Biotechnol. , vol.33 , pp. 187-197
    • Tsai, S.Q.1
  • 11
    • 84927514894 scopus 로고    scopus 로고
    • In vivo genome editing using Staphylococcus aureus Cas9
    • Ran, F. A. et al. In vivo genome editing using Staphylococcus aureus Cas9. Nature 520, 186-191 (2015).
    • (2015) Nature , vol.520 , pp. 186-191
    • Ran, F.A.1
  • 12
    • 84895871173 scopus 로고    scopus 로고
    • DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
    • Sternberg, S. H., Redding, S., Jinek, M., Greene, E. C. & Doudna, J. A. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9. Nature 507, 62-67 (2014).
    • (2014) Nature , vol.507 , pp. 62-67
    • Sternberg, S.H.1    Redding, S.2    Jinek, M.3    Greene, E.C.4    Doudna, J.A.5
  • 13
    • 84893157352 scopus 로고    scopus 로고
    • Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
    • Jinek, M. et al. Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science 343, 1247997 (2014).
    • (2014) Science , vol.343 , pp. 1247997
    • Jinek, M.1
  • 14
    • 84933574487 scopus 로고    scopus 로고
    • A Cas9-guide RNA complex preorganized for target DNA recognition
    • Jiang, F., Zhou, K., Ma, L., Gressel, S. & Doudna, J. A. A Cas9-guide RNA complex preorganized for target DNA recognition. Science 348, 1477-1481 (2015).
    • (2015) Science , vol.348 , pp. 1477-1481
    • Jiang, F.1    Zhou, K.2    Ma, L.3    Gressel, S.4    Doudna, J.A.5
  • 15
    • 84896733529 scopus 로고    scopus 로고
    • Crystal structure of Cas9 in complex with guide RNA and target DNA
    • Nishimasu, H. et al. Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell 156, 935-949 (2014).
    • (2014) Cell , vol.156 , pp. 935-949
    • Nishimasu, H.1
  • 16
    • 84908508061 scopus 로고    scopus 로고
    • Structural basis of PAMdependent target DNA recognition by the Cas9 endonuclease
    • Anders, C., Niewoehner, O., Duerst, A. & Jinek, M. Structural basis of PAMdependent target DNA recognition by the Cas9 endonuclease. Nature 513, 569-573 (2014).
    • (2014) Nature , vol.513 , pp. 569-573
    • Anders, C.1    Niewoehner, O.2    Duerst, A.3    Jinek, M.4
  • 17
    • 84884663630 scopus 로고    scopus 로고
    • Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
    • Hou, Z. et al. Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. Proc. Natl Acad. Sci. USA 110, 15644-15649 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 15644-15649
    • Hou, Z.1
  • 18
    • 23644433196 scopus 로고    scopus 로고
    • Measurements of internal distance changes of the 30S ribosome using FRET with multiple donor-acceptor pairs: Quantitative spectroscopic methods
    • Majumdar, Z. K., Hickerson, R., Noller, H. F. & Clegg, R. M. Measurements of internal distance changes of the 30S ribosome using FRET with multiple donor-acceptor pairs: quantitative spectroscopic methods. J. Mol. Biol. 351, 1123-1145 (2005).
    • (2005) J. Mol. Biol. , vol.351 , pp. 1123-1145
    • Majumdar, Z.K.1    Hickerson, R.2    Noller, H.F.3    Clegg, R.M.4
  • 19
    • 0026687952 scopus 로고
    • Fluorescence resonance energy transfer and nucleic acids
    • Clegg, R. M. Fluorescence resonance energy transfer and nucleic acids. Methods Enzymol. 211, 353-388 (1992).
    • (1992) Methods Enzymol. , vol.211 , pp. 353-388
    • Clegg, R.M.1
  • 20
    • 84924322574 scopus 로고    scopus 로고
    • Rational design of a split-Cas9 enzyme complex
    • Wright, A. V. et al. Rational design of a split-Cas9 enzyme complex. Proc. Natl Acad. Sci. USA 112, 2984-2989 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 2984-2989
    • Wright, A.V.1
  • 21
    • 34948885722 scopus 로고    scopus 로고
    • Crystal structure of T4 endonuclease VII resolving a Holliday junction
    • Biertümpfel, C., Yang, W. & Suck, D. Crystal structure of T4 endonuclease VII resolving a Holliday junction. Nature 449, 616-620 (2007).
    • (2007) Nature , vol.449 , pp. 616-620
    • Biertümpfel, C.1    Yang, W.2    Suck, D.3
  • 22
    • 84903975702 scopus 로고    scopus 로고
    • Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
    • Szczelkun, M. D. et al. Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes. Proc. Natl Acad. Sci. USA 111, 9798-9803 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 9798-9803
    • Szczelkun, M.D.1
  • 23
    • 84907546073 scopus 로고    scopus 로고
    • Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage
    • Cencic, R. et al. Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage. PLoS One 9, e109213 (2014).
    • (2014) PLoS One , vol.9 , pp. e109213
    • Cencic, R.1
  • 24
    • 84896929630 scopus 로고    scopus 로고
    • Improving CRISPRCas nuclease specificity using truncated guide RNAs
    • Fu, Y., Sander, J. D., Reyon, D., Cascio, V. M. & Joung, J. K. Improving CRISPRCas nuclease specificity using truncated guide RNAs. Nature Biotechnol. 32, 279-284 (2014).
    • (2014) Nature Biotechnol. , vol.32 , pp. 279-284
    • Fu, Y.1    Sander, J.D.2    Reyon, D.3    Cascio, V.M.4    Joung, J.K.5
  • 25
    • 84866859751 scopus 로고    scopus 로고
    • Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
    • Gasiunas, G., Barrangou, R., Horvath, P. & Siksnys, V. Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proc. Natl Acad. Sci. USA 109, E2579-E2586 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. E2579-E2586
    • Gasiunas, G.1    Barrangou, R.2    Horvath, P.3    Siksnys, V.4
  • 26
    • 84940368054 scopus 로고    scopus 로고
    • Crystal structure of Staphylococcus aureus Cas9
    • Nishimasu, H. et al. Crystal structure of Staphylococcus aureus Cas9. Cell 162, 1113-1126 (2015).
    • (2015) Cell , vol.162 , pp. 1113-1126
    • Nishimasu, H.1
  • 27
    • 84924592451 scopus 로고    scopus 로고
    • Directional R-loop formation by the CRISPR-Cas surveillance complex cascade provides efficient off-target site rejection
    • Rutkauskas, M. et al. Directional R-loop formation by the CRISPR-Cas surveillance complex cascade provides efficient off-target site rejection. Cell Reports 10, 1534-1543 (2015).
    • (2015) Cell Reports , vol.10 , pp. 1534-1543
    • Rutkauskas, M.1
  • 28
    • 84922322005 scopus 로고    scopus 로고
    • Guide RNA functional modules direct Cas9 activity and orthogonality
    • Briner, A. E. et al. Guide RNA functional modules direct Cas9 activity and orthogonality. Mol. Cell 56, 333-339 (2014).
    • (2014) Mol. Cell , vol.56 , pp. 333-339
    • Briner, A.E.1
  • 29
    • 84904790793 scopus 로고    scopus 로고
    • Deciphering key features in protein structures with the new ENDscript server
    • Robert, X. & Gouet, P. Deciphering key features in protein structures with the new ENDscript server. Nucleic Acids Res. 42, W320-W324 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. W320-W324
    • Robert, X.1    Gouet, P.2
  • 30
    • 84858659496 scopus 로고    scopus 로고
    • Mechanism of substrate selection by a highly specific CRISPR endoribonuclease
    • Sternberg, S. H., Haurwitz, R. E. & Doudna, J. A. Mechanism of substrate selection by a highly specific CRISPR endoribonuclease. RNA 18, 661-672 (2012).
    • (2012) RNA , vol.18 , pp. 661-672
    • Sternberg, S.H.1    Haurwitz, R.E.2    Doudna, J.A.3
  • 31
    • 77954257799 scopus 로고    scopus 로고
    • ConSurf 2010: Calculating evolutionary conservation in sequence and structure of proteins and nucleic acids
    • Ashkenazy, H., Erez, E., Martz, E., Pupko, T. & Ben-Tal, N. ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids. Nucleic Acids Res. 38, W529-W533 (2010).
    • (2010) Nucleic Acids Res. , vol.38 , pp. W529-W533
    • Ashkenazy, H.1    Erez, E.2    Martz, E.3    Pupko, T.4    Ben-Tal, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.