-
1
-
-
84902096048
-
Development and applications of CRISPR-Cas9 for genome engineering
-
Hsu, P.D., Lander, E.S. & Zhang, F. Development and applications of CRISPR-Cas9 for genome engineering. Cell 157, 1262-1278 (2014).
-
(2014)
Cell
, vol.157
, pp. 1262-1278
-
-
Hsu, P.D.1
Lander, E.S.2
Zhang, F.3
-
2
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber, M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 79, 181-211 (2010).
-
(2010)
Annu. Rev. Biochem
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
3
-
-
52049098230
-
Comparison of nonhomologous end joining and homologous recombination in human cells
-
Mao, Z., Bozzella, M., Seluanov, A. & Gorbunova, V. Comparison of nonhomologous end joining and homologous recombination in human cells. DNA Repair (Amst.) 7, 1765-1771 (2008).
-
(2008)
DNA Repair (Amst.)
, vol.7
, pp. 1765-1771
-
-
Mao, Z.1
Bozzella, M.2
Seluanov, A.3
Gorbunova, V.4
-
4
-
-
84892765883
-
Genome-scale CRISPR-Cas9 knockout screening in human cells
-
Shalem, O. et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 343, 84-87 (2014).
-
(2014)
Science
, vol.343
, pp. 84-87
-
-
Shalem, O.1
-
5
-
-
50649100744
-
Mechanism of eukaryotic homologous recombination
-
San Filippo, J., Sung, P. & Klein, H. Mechanism of eukaryotic homologous recombination. Annu. Rev. Biochem. 77, 229-257 (2008).
-
(2008)
Annu. Rev. Biochem
, vol.77
, pp. 229-257
-
-
San Filippo, J.1
Sung, P.2
Klein, H.3
-
6
-
-
70349313064
-
Genetic analysis of zinc-finger nuclease-induced gene targeting in Drosophila
-
Bozas, A., Beumer, K.J., Trautman, J.K. & Carroll, D. Genetic analysis of zinc-finger nuclease-induced gene targeting in Drosophila. Genetics 182, 641-651 (2009).
-
(2009)
Genetics
, vol.182
, pp. 641-651
-
-
Bozas, A.1
Beumer, K.J.2
Trautman, J.K.3
Carroll, D.4
-
7
-
-
79960978444
-
Tracking genome engineering outcome at individual DNA breakpoints
-
Certo, M.T. et al. Tracking genome engineering outcome at individual DNA breakpoints. Nat. Methods 8, 671-676 (2011).
-
(2011)
Nat. Methods
, vol.8
, pp. 671-676
-
-
Certo, M.T.1
-
8
-
-
0026070440
-
Targeted integration of adeno-associated virus (AAV) into human chromosome 19
-
Samulski, R.J. et al. Targeted integration of adeno-associated virus (AAV) into human chromosome 19. EMBO J. 10, 3941-3950 (1991).
-
(1991)
EMBO J.
, vol.10
, pp. 3941-3950
-
-
Samulski, R.J.1
-
9
-
-
84886429265
-
Push back to respond better: Regulatory inhibition of the DNA double-strand break response
-
Panier, S. & Durocher, D. Push back to respond better: regulatory inhibition of the DNA double-strand break response. Nat. Rev. Mol. Cell Biol. 14, 661-672 (2013).
-
(2013)
Nat. Rev. Mol. Cell Biol
, vol.14
, pp. 661-672
-
-
Panier, S.1
Durocher, D.2
-
10
-
-
84871550828
-
An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression
-
Srivastava, M. et al. An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression. Cell 151, 1474-1487 (2012).
-
(2012)
Cell
, vol.151
, pp. 1474-1487
-
-
Srivastava, M.1
-
11
-
-
78650648624
-
The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity
-
Cheng, C.Y. et al. The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity. J. Virol. 85, 765-775 (2011).
-
(2011)
J. Virol
, vol.85
, pp. 765-775
-
-
Cheng, C.Y.1
-
12
-
-
79551711967
-
Serotype-specific inactivation of the cellular DNA damage response during adenovirus infection
-
Forrester, N.A. et al. Serotype-specific inactivation of the cellular DNA damage response during adenovirus infection. J. Virol. 85, 2201-2211 (2011).
-
(2011)
J. Virol
, vol.85
, pp. 2201-2211
-
-
Forrester, N.A.1
-
13
-
-
84919448721
-
Blurring the line between the DNA damage response and transcription: The importance of chromatin dynamics
-
Adam, S. & Polo, S.E. Blurring the line between the DNA damage response and transcription: the importance of chromatin dynamics. Exp. Cell Res. 329, 148-153 (2014).
-
(2014)
Exp. Cell Res
, vol.329
, pp. 148-153
-
-
Adam, S.1
Polo, S.E.2
-
14
-
-
77950817518
-
Histone modifications: Crucial elements for damage response and chromatin restoration
-
Zhu, Q. & Wani, A.A. Histone modifications: crucial elements for damage response and chromatin restoration. J. Cell. Physiol. 223, 283-288 (2010).
-
(2010)
J. Cell. Physiol
, vol.223
, pp. 283-288
-
-
Zhu, Q.1
Wani, A.A.2
-
15
-
-
84900439412
-
Alternative end-joining pathway(s): Bricolage at DNA breaks
-
Frit, P., Barboule, N., Yuan, Y., Gomez, D. & Calsou, P. Alternative end-joining pathway(s): bricolage at DNA breaks. DNA Repair (Amst.) 17, 81-97 (2014).
-
(2014)
DNA Repair (Amst.)
, vol.17
, pp. 81-97
-
-
Frit, P.1
Barboule, N.2
Yuan, Y.3
Gomez, D.4
Calsou, P.5
-
16
-
-
70350304558
-
PI3 kinase signals BCR-dependent mature B cell survival
-
Srinivasan, L. et al. PI3 kinase signals BCR-dependent mature B cell survival. Cell 139, 573-586 (2009).
-
(2009)
Cell
, vol.139
, pp. 573-586
-
-
Srinivasan, L.1
-
17
-
-
78650648624
-
The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity
-
Cheng, C.Y. et al. The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity. J. Virol. 85, 765-775 (2011).
-
(2011)
J. Virol
, vol.85
, pp. 765-775
-
-
Cheng, C.Y.1
-
18
-
-
84921378853
-
Human adenovirus: Viral pathogen with increasing importance
-
Ghebremedhin, B. Human adenovirus: viral pathogen with increasing importance. Eur. J. Microbiol. Immunol. 4, 26-33 (2014).
-
(2014)
Eur. J. Microbiol. Immunol
, vol.4
, pp. 26-33
-
-
Ghebremedhin, B.1
-
20
-
-
84920867879
-
A mouse geneticist's practical guide to CRISPR applications
-
Singh, P., Schimenti, J.C. & Bolcun-Filas, E. A mouse geneticist's practical guide to CRISPR applications. Genetics 199, 1-15 (2015).
-
(2015)
Genetics
, vol.199
, pp. 1-15
-
-
Singh, P.1
Schimenti, J.C.2
Bolcun-Filas, E.3
-
21
-
-
84905905141
-
An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells
-
González, F. et al. An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells. Cell Stem Cell 15, 215-226 (2014).
-
(2014)
Cell Stem Cell
, vol.15
, pp. 215-226
-
-
González, F.1
-
22
-
-
0035005706
-
The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences
-
Donnelly, M.L. et al. The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences. J. Gen. Virol. 82, 1027-1041 (2001).
-
(2001)
J. Gen. Virol
, vol.82
, pp. 1027-1041
-
-
Donnelly, M.L.1
-
23
-
-
34547659144
-
Bright monomeric red fluorescent protein with an extended fluorescence lifetime
-
Merzlyak, E.M. et al. Bright monomeric red fluorescent protein with an extended fluorescence lifetime. Nat. Methods 4, 555-557 (2007).
-
(2007)
Nat. Methods
, vol.4
, pp. 555-557
-
-
Merzlyak, E.M.1
-
24
-
-
28944447801
-
Ku70, a component of DNA-dependent protein kinase, is a mammalian receptor for Rickettsia conorii
-
Martinez, J.J., Seveau, S., Veiga, E., Matsuyama, S. & Cossart, P. Ku70, a component of DNA-dependent protein kinase, is a mammalian receptor for Rickettsia conorii. Cell 123, 1013-1023 (2005).
-
(2005)
Cell
, vol.123
, pp. 1013-1023
-
-
Martinez, J.J.1
Seveau, S.2
Veiga, E.3
Matsuyama, S.4
Cossart, P.5
-
25
-
-
36749055667
-
Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis
-
Com, E. et al. Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis. Mol. Cell. Proteomics 6, 1842-1854 (2007).
-
(2007)
Mol. Cell. Proteomics
, vol.6
, pp. 1842-1854
-
-
Com, E.1
-
26
-
-
80052103373
-
Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells
-
Li, B., Reddy, S. & Comai, L. Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells. Aging 3, 395-406 (2011).
-
(2011)
Aging
, vol.3
, pp. 395-406
-
-
Li, B.1
Reddy, S.2
Comai, L.3
-
27
-
-
27744600086
-
Ku80 autoantigen as a cellular coreceptor for human parvovirus B19 infection
-
Munakata, Y. et al. Ku80 autoantigen as a cellular coreceptor for human parvovirus B19 infection. Blood 106, 3449-3456 (2005).
-
(2005)
Blood
, vol.106
, pp. 3449-3456
-
-
Munakata, Y.1
-
28
-
-
34249666089
-
Knockdown of DNA ligase IV/XRCC4 by RNA interference inhibits herpes simplex virus type i DNA replication
-
Muylaert, I. & Elias, P. Knockdown of DNA ligase IV/XRCC4 by RNA interference inhibits herpes simplex virus type I DNA replication. J. Biol. Chem. 282, 10865-10872 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 10865-10872
-
-
Muylaert, I.1
Elias, P.2
-
29
-
-
34848828539
-
Low levels of DNA ligases III and IV sufficient for effective NHEJ
-
Windhofer, F., Wu, W. & Iliakis, G. Low levels of DNA ligases III and IV sufficient for effective NHEJ. J. Cell. Physiol. 213, 475-483 (2007).
-
(2007)
J. Cell. Physiol
, vol.213
, pp. 475-483
-
-
Windhofer, F.1
Wu, W.2
Iliakis, G.3
-
30
-
-
84873729095
-
Multiplex genome engineering using CRISPR-Cas systems
-
Cong, L. et al. Multiplex genome engineering using CRISPR-Cas systems. Science 339, 819-823 (2013).
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
|