메뉴 건너뛰기




Volumn 56, Issue , 2005, Pages 401-423

The silent revolution: RNA interference as basic biology, research tool, and therapeutic

Author keywords

miRNA; Posttranscriptional gene silencing gene therapy; Small interfering RNA

Indexed keywords

COMPLEMENTARY RNA; MESSENGER RNA; RNA; RNA INDUCED SILENCING COMPLEX; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

EID: 14544280255     PISSN: 00664219     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.med.56.082103.104606     Document Type: Review
Times cited : (308)

References (115)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, et al. 1998. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-11
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 2
    • 0025134418 scopus 로고
    • Altered gene expression in plants due to trans interactions between homologous genes
    • Jorgensen R. 1990. Altered gene expression in plants due to trans interactions between homologous genes. Trends Biotechnol. 8:340-44
    • (1990) Trends Biotechnol. , vol.8 , pp. 340-344
    • Jorgensen, R.1
  • 3
    • 0026441194 scopus 로고
    • Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
    • Romano N, Macino G. 1992. Quelling: transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Mol. Microbiol. 6:3343-53
    • (1992) Mol. Microbiol. , vol.6 , pp. 3343-3353
    • Romano, N.1    Macino, G.2
  • 4
    • 0036437372 scopus 로고    scopus 로고
    • Control of developmental timing by microRNAs and their targets
    • Pasquinelli AE, Ruvkun G. 2002. Control of developmental timing by microRNAs and their targets. Annu. Rev. Cell Dev. Biol. 18:495-513
    • (2002) Annu. Rev. Cell Dev. Biol. , vol.18 , pp. 495-513
    • Pasquinelli, A.E.1    Ruvkun, G.2
  • 5
    • 0034633770 scopus 로고    scopus 로고
    • AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
    • Fagard M, Boutet S, Morel JB, et al. 2000. AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals. Proc. Natl. Acad. Sci. USA 97:11650-54
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11650-11654
    • Fagard, M.1    Boutet, S.2    Morel, J.B.3
  • 7
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM, et al. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409:363-66
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3
  • 8
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, et al. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494-98
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3
  • 9
    • 0033572660 scopus 로고    scopus 로고
    • Targeted mRNA degradation by double-stranded RNA in vitro
    • Tuschl T, Zamore PD, Lehmann R, et al. 1999. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 13:3191-97
    • (1999) Genes Dev. , vol.13 , pp. 3191-3197
    • Tuschl, T.1    Zamore, P.D.2    Lehmann, R.3
  • 10
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore PD, Tuschl T, Sharp PA, et al. 2000. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101:25-33
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3
  • 11
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in post-transcriptional gene silencing in plants
    • Hamilton AJ, Baulcombe DC. 1999. A species of small antisense RNA in post-transcriptional gene silencing in plants. Science 286:950-52
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.J.1    Baulcombe, D.C.2
  • 12
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond SM, Bernstein E, Beach D, et al. 2000. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404:293-96
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3
  • 13
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir SM, Martinez J, Patkaniowska A, et al. 2001. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20:6877-88
    • (2001) EMBO J. , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3
  • 15
    • 0141868916 scopus 로고    scopus 로고
    • R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
    • Liu Q, Rand TA, Kalidas S, et al. 2003. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301:1921-25
    • (2003) Science , vol.301 , pp. 1921-1925
    • Liu, Q.1    Rand, T.A.2    Kalidas, S.3
  • 16
    • 1842766252 scopus 로고    scopus 로고
    • A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila
    • Pham JW, Pellino JL, Lee YS, et al. 2004. A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117:83-94
    • (2004) Cell , vol.117 , pp. 83-94
    • Pham, J.W.1    Pellino, J.L.2    Lee, Y.S.3
  • 17
    • 1642603943 scopus 로고    scopus 로고
    • RISC assembly defects in the Drosophila RNAi mutant armitage
    • Tomari Y, Du T, Haley B, et al. 2004. RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 116:831-41
    • (2004) Cell , vol.116 , pp. 831-841
    • Tomari, Y.1    Du, T.2    Haley, B.3
  • 18
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • Hammond SM, Boettcher S, Caudy AA, et al. 2001. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293:1146-50
    • (2001) Science , vol.293 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3
  • 19
    • 0141843655 scopus 로고    scopus 로고
    • A micrococcal nuclease homologue in RNAi effector complexes
    • Caudy AA, Ketting RF, Hammond SM, et al. 2003. A micrococcal nuclease homologue in RNAi effector complexes. Nature 425:411-14
    • (2003) Nature , vol.425 , pp. 411-414
    • Caudy, A.A.1    Ketting, R.F.2    Hammond, S.M.3
  • 20
    • 0036792769 scopus 로고    scopus 로고
    • Fragile X-related protein and VIG associate with the RNA interference machinery
    • Caudy AA, Myers M, Hannon GJ, et al. 2002. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes. Dev. 16:2491-96
    • (2002) Genes. Dev. , vol.16 , pp. 2491-2496
    • Caudy, A.A.1    Myers, M.2    Hannon, G.J.3
  • 21
    • 4444368187 scopus 로고    scopus 로고
    • Argonaute2 is the catalytic engine of mammalian RNAi
    • Liu J, Carmell MA, Rivas FV, et al. 2004. Argonaute2 is the catalytic engine of mammalian RNAi. Science 305:1437-41
    • (2004) Science , vol.305 , pp. 1437-1441
    • Liu, J.1    Carmell, M.A.2    Rivas, F.V.3
  • 22
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of Argonaute and its implications for RISC Slicer activity
    • Song JJ, Smith SK, Hannon GJ, et al. 2004. Crystal structure of Argonaute and its implications for RISC Slicer activity. Science 305:1434-37
    • (2004) Science , vol.305 , pp. 1434-1437
    • Song, J.J.1    Smith, S.K.2    Hannon, G.J.3
  • 23
    • 1342346710 scopus 로고    scopus 로고
    • A conserved siRNA-degrading RNase negatively r egulates RNA interference in C. elegans
    • Kennedy S, Wang D, Ruvkun G. 2004. A conserved siRNA-degrading RNase negatively r egulates RNA interference in C. elegans. Nature 427:645-49
    • (2004) Nature , vol.427 , pp. 645-649
    • Kennedy, S.1    Wang, D.2    Ruvkun, G.3
  • 24
  • 25
    • 0041941514 scopus 로고    scopus 로고
    • The small RNA profile during Drosophila melanogaster development
    • Aravin AA, Lagos-Quintana M, Yalcin A, et al. 2003. The small RNA profile during Drosophila melanogaster development. Dev. Cell 5:337-50
    • (2003) Dev. Cell , vol.5 , pp. 337-350
    • Aravin, A.A.1    Lagos-Quintana, M.2    Yalcin, A.3
  • 26
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Lee Y, Jeon K, Lee JT, et al. 2002. MicroRNA maturation: stepwise processing and subcellular localization. EMBO. J. 21:4663-70
    • (2002) EMBO. J. , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.T.3
  • 27
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Lee Y, Ahn C, Han J, et al. 2003. The nuclear RNase III Drosha initiates microRNA processing. Nature 425:415-19
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3
  • 30
    • 0142173075 scopus 로고    scopus 로고
    • Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells
    • Saxena S, Jonsson ZO, Dutta A. 2003. Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells. J. Biol. Chem. 278:44312-19
    • (2003) J. Biol. Chem. , vol.278 , pp. 44312-44319
    • Saxena, S.1    Jonsson, Z.O.2    Dutta, A.3
  • 31
    • 0037321349 scopus 로고    scopus 로고
    • New microRNAs from mouse and human
    • Lagos-Quintana M, Rauhut R, Meyer J, et al. 2003. New microRNAs from mouse and human. RNA 9:175-79
    • (2003) RNA , vol.9 , pp. 175-179
    • Lagos-Quintana, M.1    Rauhut, R.2    Meyer, J.3
  • 32
    • 0035160923 scopus 로고    scopus 로고
    • RNA interference in Trypanosoma brucei: Cloning of small interfering RNAs provides evidence for retroposori-derived 24-26-nucleotide RNAs
    • Djikeng A, Shi H, Tschudi C, et al. 2001. RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposori-derived 24-26-nucleotide RNAs. RNA 7:1522-30
    • (2001) RNA , vol.7 , pp. 1522-1530
    • Djikeng, A.1    Shi, H.2    Tschudi, C.3
  • 33
    • 0037072660 scopus 로고    scopus 로고
    • Small RNAs correspond to centromere heterochromatic repeats
    • Reinhart BJ, Bartel DP. 2002. Small RNAs correspond to centromere heterochromatic repeats. Science 297:1831
    • (2002) Science , vol.297 , pp. 1831
    • Reinhart, B.J.1    Bartel, D.P.2
  • 34
    • 0037474126 scopus 로고    scopus 로고
    • ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation
    • Zilberman D, Cao X, Jacobsen SE. 2003. ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science 299:716-19
    • (2003) Science , vol.299 , pp. 716-719
    • Zilberman, D.1    Cao, X.2    Jacobsen, S.E.3
  • 35
    • 0032717319 scopus 로고    scopus 로고
    • The rde-1 gene, RNA interference, and transposon silencing in C. elegans
    • Tabara H, Sarkissian M, Kelly WG, et al. 1999. The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99:123-32
    • (1999) Cell , vol.99 , pp. 123-132
    • Tabara, H.1    Sarkissian, M.2    Kelly, W.G.3
  • 36
    • 0042831010 scopus 로고    scopus 로고
    • Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing
    • Schramke V, Allshire R. 2003. Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing. Science 301:1069-74
    • (2003) Science , vol.301 , pp. 1069-1074
    • Schramke, V.1    Allshire, R.2
  • 37
    • 1442305898 scopus 로고    scopus 로고
    • RNA silencing genes control de novo DNA methylation
    • Chan SW, Zilberman D, Xie Z, et al. 2004. RNA silencing genes control de novo DNA methylation. Science 303:1336
    • (2004) Science , vol.1336 , pp. 303
    • Chan, S.W.1    Zilberman, D.2    Xie, Z.3
  • 38
    • 0038738781 scopus 로고    scopus 로고
    • RNA interference is required for normal centromere function in fission yeast
    • Volpe T, Schramke V, Hamilton GL, et al. 2003. RNA interference is required for normal centromere function in fission yeast. Chromosome Res. 11:137-46
    • (2003) Chromosome Res. , vol.11 , pp. 137-146
    • Volpe, T.1    Schramke, V.2    Hamilton, G.L.3
  • 39
    • 0942279615 scopus 로고    scopus 로고
    • Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery
    • Pal-Bhadra M, Leibovitch BA, Gandhi SG, et al. 2004. Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science 303:669-72
    • (2004) Science , vol.303 , pp. 669-672
    • Pal-Bhadra, M.1    Leibovitch, B.A.2    Gandhi, S.G.3
  • 40
    • 0942279635 scopus 로고    scopus 로고
    • RNAi-mediated targeting of heterochromatin by the RITS complex
    • Verdel A, Jia S, Gerber S, et al. 2004. RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303:672-76
    • (2004) Science , vol.303 , pp. 672-676
    • Verdel, A.1    Jia, S.2    Gerber, S.3
  • 41
    • 4143149753 scopus 로고    scopus 로고
    • Dicer is essential for formation of the heterochromatin structure in vertebrate cells
    • Fukagawa T, Nogami M, Yoshikawa M, et al. 2004. Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nat. Cell Biol. 6:78491
    • (2004) Nat. Cell Biol. , vol.6 , pp. 78491
    • Fukagawa, T.1    Nogami, M.2    Yoshikawa, M.3
  • 42
    • 4344705410 scopus 로고    scopus 로고
    • Small interfering RNA-induced transcriptional gene silencing in human cells
    • a. Morris KV, Chan SW-L, Jacobsen SE, Looney DJ. 2004. Small interfering RNA-induced transcriptional gene silencing in human cells. Science 305:1289-92
    • (2004) Science , vol.305 , pp. 1289-1292
    • Morris, K.V.1    Chan, S.W.-L.2    Jacobsen, S.E.3    Looney, D.J.4
  • 43
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp TR, Bernards R, Agami R. 2002. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2:243-47
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 44
    • 0242379146 scopus 로고    scopus 로고
    • Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis
    • Ding H, Schwarz DS, Keene A, et al. 2003. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell 2:209-17
    • (2003) Aging Cell , vol.2 , pp. 209-217
    • Ding, H.1    Schwarz, D.S.2    Keene, A.3
  • 45
    • 1342306385 scopus 로고    scopus 로고
    • Targeting Alzheimer's disease genes with RNA interference: An efficient strategy for silencing mutant alleles
    • Miller VM, Gouvion CM, Davidson BL, et al. 2004. Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles. Nucleic Acids Res. 32:661-68
    • (2004) Nucleic Acids Res. , vol.32 , pp. 661-668
    • Miller, V.M.1    Gouvion, C.M.2    Davidson, B.L.3
  • 46
    • 0037173613 scopus 로고    scopus 로고
    • Short interfering RNA confers intracellular antiviral immunity in human cells
    • Gitlin L, Karelsky S, Andino R. 2002. Short interfering RNA confers intracellular antiviral immunity in human cells. Nature 418:430-34
    • (2002) Nature , vol.418 , pp. 430-434
    • Gitlin, L.1    Karelsky, S.2    Andino, R.3
  • 47
    • 1242319384 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 escapes from RNA interference- mediated inhibition
    • Das AT, Brummelkamp TR, Westerhout EM, et al. 2004. Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J. Virol. 78:2601-5
    • (2004) J. Virol. , vol.78 , pp. 2601-2605
    • Das, A.T.1    Brummelkamp, T.R.2    Westerhout, E.M.3
  • 48
    • 0142124143 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 escape from RNA interference
    • Boden D, Pusch O, Lee F, et al. 2003. Human immunodeficiency virus type 1 escape from RNA interference. J. Virol. 77:11531-35
    • (2003) J. Virol. , vol.77 , pp. 11531-11535
    • Boden, D.1    Pusch, O.2    Lee, F.3
  • 49
    • 0037173610 scopus 로고    scopus 로고
    • Modulation of HIV-1 replication by RNA interference
    • Jacque JM, Triques K, Stevenson M. 2002. Modulation of HIV-1 replication by RNA interference. Nature 418:435-38
    • (2002) Nature , vol.418 , pp. 435-438
    • Jacque, J.M.1    Triques, K.2    Stevenson, M.3
  • 50
    • 0038606999 scopus 로고    scopus 로고
    • Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
    • Czauderna F, Fechtner M, Dames S, et al. 2003. Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res. 31:2705-16
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2705-2716
    • Czauderna, F.1    Fechtner, M.2    Dames, S.3
  • 51
    • 0037440005 scopus 로고    scopus 로고
    • Tolerance for mutations and chemical modifications in a siRNA
    • Amarzguioui M, Holen T, Babaie E, et al. 2003. Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res. 31:589-95
    • (2003) Nucleic Acids Res. , vol.31 , pp. 589-595
    • Amarzguioui, M.1    Holen, T.2    Babaie, E.3
  • 52
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir SM, Lendeckel W, Tuschl T. 2001. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15:188-200
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 53
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • Khvorova A, Reynolds A, Jayasena SD. 2003. Functional siRNAs and miRNAs exhibit strand bias. Cell 115:209-16
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 54
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • Schwarz DS, Hutvagner G, Du T, et al. 2003. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115:199-208
    • (2003) Cell , vol.115 , pp. 199-208
    • Schwarz, D.S.1    Hutvagner, G.2    Du, T.3
  • 55
    • 0037685280 scopus 로고    scopus 로고
    • Expression profiling reveals off-target gene regulation by RNAi
    • Jackson AL, Bartz SR, Schelter J, et al. 2003. Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol. 21:635-37
    • (2003) Nat. Biotechnol. , vol.21 , pp. 635-637
    • Jackson, A.L.1    Bartz, S.R.2    Schelter, J.3
  • 57
    • 0347623204 scopus 로고    scopus 로고
    • Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)
    • Persengiev SP, Zhu X, Green MR. 2004. Nonspecific, concentration- dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs). RNA 10:12-18
    • (2004) RNA , vol.10 , pp. 12-18
    • Persengiev, S.P.1    Zhu, X.2    Green, M.R.3
  • 58
    • 0042972933 scopus 로고    scopus 로고
    • Activation of the Interferon system by short-interfering RNAs
    • Sledz CA, Holko M, de Veer MJ, et al. 2003. Activation of the Interferon system by short-interfering RNAs. Nat. Cell Biol. 5:834-39
    • (2003) Nat. Cell Biol. , vol.5 , pp. 834-839
    • Sledz, C.A.1    Holko, M.2    De Veer, M.J.3
  • 59
    • 0038419800 scopus 로고    scopus 로고
    • Induction of an interferon response by RNAi vectors in mammalian cells
    • Bridge AJ, Pebernard S, Ducraux A, et al. 2003. Induction of an interferon response by RNAi vectors in mammalian cells. Nat. Genet. 34:263-64
    • (2003) Nat. Genet. , vol.34 , pp. 263-264
    • Bridge, A.J.1    Pebernard, S.2    Ducraux, A.3
  • 60
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Zeng Y, Wagner EJ, Cullen BR. 2002. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 9:1327-33
    • (2002) Mol. Cell , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 61
    • 0035859046 scopus 로고    scopus 로고
    • Gene silencing as an adaptive defence against viruses
    • Waterhouse PM, Wang MB, Lough T. 2001. Gene silencing as an adaptive defence against viruses. Nature 411:834-42
    • (2001) Nature , vol.411 , pp. 834-842
    • Waterhouse, P.M.1    Wang, M.B.2    Lough, T.3
  • 62
    • 0347357615 scopus 로고    scopus 로고
    • Recognition of small interfering RNA by a viral suppressor of RNA silencing
    • Ye K, Malinina L, Patel DJ. 2003. Recognition of small interfering RNA by a viral suppressor of RNA silencing. Nature 426:874-78
    • (2003) Nature , vol.426 , pp. 874-878
    • Ye, K.1    Malinina, L.2    Patel, D.J.3
  • 63
    • 12144291576 scopus 로고    scopus 로고
    • On the role of RNA silencing in the pathogenicity and evolution of viroids and viral satellites
    • Wang MB, Bian XY, Wu LM, et al. 2004. On the role of RNA silencing in the pathogenicity and evolution of viroids and viral satellites. Proc. Natl. Acad. Sci. USA 101:3275-80
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 3275-3280
    • Wang, M.B.1    Bian, X.Y.2    Wu, L.M.3
  • 64
    • 2342420041 scopus 로고    scopus 로고
    • Identification of virus-encoded microRNAs
    • Pfeffer S, Zavolan M, Grasser FA, et al. 2004. Identification of virus-encoded microRNAs. Science 304:734-36
    • (2004) Science , vol.304 , pp. 734-736
    • Pfeffer, S.1    Zavolan, M.2    Grasser, F.A.3
  • 65
    • 10744225684 scopus 로고    scopus 로고
    • Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing
    • Li WX, Li H, Lu R, et al. 2004. Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc. Natl. Acad. Sci. USA 101:1350-55
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1350-1355
    • Li, W.X.1    Li, H.2    Lu, R.3
  • 66
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. 2004. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-97
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 67
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of mammalian microRNA targets
    • Lewis BP, Shih IH, Jones-Rhoades MW, et al. 2003. Prediction of mammalian microRNA targets. Cell 115:787-98
    • (2003) Cell , vol.115 , pp. 787-798
    • Lewis, B.P.1    Shih, I.H.2    Jones-Rhoades, M.W.3
  • 68
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • Wightman B, Ha I, Ruvkun G. 1993. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75:855-62
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 69
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. 1993. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-54
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 70
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • Chen CZ, Li L, Lodish HF, et al. 2004. MicroRNAs modulate hematopoietic lineage differentiation. Science 303:83-86
    • (2004) Science , vol.303 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3
  • 71
    • 0037663944 scopus 로고    scopus 로고
    • Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages
    • Song E, Lee SK, Dykxhoorn DM, et al. 2003. Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. J. Virol. 77:7174-81
    • (2003) J. Virol. , vol.77 , pp. 7174-7181
    • Song, E.1    Lee, S.K.2    Dykxhoorn, D.M.3
  • 72
    • 0037348329 scopus 로고    scopus 로고
    • RNA interference targeting Fas protects mice from fulminant hepatitis
    • Song E, Lee SK, Wang J, et al. 2003. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat. Med. 9:347-51
    • (2003) Nat. Med. , vol.9 , pp. 347-351
    • Song, E.1    Lee, S.K.2    Wang, J.3
  • 73
    • 0842346323 scopus 로고    scopus 로고
    • Long-lasting RNAi activity in mammalian neurons
    • Omi K, Tokunaga K, Hohjoh H. 2004. Long-lasting RNAi activity in mammalian neurons. FEBS Lett. 558:89-95
    • (2004) FEBS Lett. , vol.558 , pp. 89-95
    • Omi, K.1    Tokunaga, K.2    Hohjoh, H.3
  • 74
    • 3242677639 scopus 로고    scopus 로고
    • siRNAs: Applications in functional genomics and potential as therapeutics
    • Dorsett Y, Tuschl T. 2004. siRNAs: applications in functional genomics and potential as therapeutics. Nat. Rev. Drug. Discov. 3:318-29
    • (2004) Nat. Rev. Drug. Discov. , vol.3 , pp. 318-329
    • Dorsett, Y.1    Tuschl, T.2
  • 75
    • 0034676457 scopus 로고    scopus 로고
    • Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
    • Fraser AG, Kamath RS, Zipperlen P, et al. 2000. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature. 408:325-30
    • (2000) Nature , vol.408 , pp. 325-330
    • Fraser, A.G.1    Kamath, R.S.2    Zipperlen, P.3
  • 76
    • 0842309871 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of growth and viability in Drosophila cells
    • Boutros M, Kiger AA, Armknecht S, et al. 2004. Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303:832-35
    • (2004) Science , vol.303 , pp. 832-835
    • Boutros, M.1    Kiger, A.A.2    Armknecht, S.3
  • 77
    • 12144288006 scopus 로고    scopus 로고
    • A resource for large-scale RNA-interference-based screens in mammals
    • Paddison PJ, Silva JM, Conklin DS, et al. 2004. A resource for large-scale RNA-interference-based screens in mammals. Nature 428:427-31
    • (2004) Nature , vol.428 , pp. 427-431
    • Paddison, P.J.1    Silva, J.M.2    Conklin, D.S.3
  • 78
    • 12144289681 scopus 로고    scopus 로고
    • A large-scale RNAi screen in human cells identifies new components of the p53 pathway
    • Berns K, Hijmans EM, Mullenders J, et al. 2004. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428:431-37
    • (2004) Nature , vol.428 , pp. 431-437
    • Berns, K.1    Hijmans, E.M.2    Mullenders, J.3
  • 79
    • 0032578911 scopus 로고    scopus 로고
    • Specific interference by ingested dsRNA
    • Timmons L, Fire A. 1998. Specific interference by ingested dsRNA. Nature 395:854
    • (1998) Nature , vol.395 , pp. 854
    • Timmons, L.1    Fire, A.2
  • 80
    • 0036468677 scopus 로고    scopus 로고
    • Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
    • Lois C, Hong EJ, Pease S, et al. 2002. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 295:868-72
    • (2002) Science , vol.295 , pp. 868-872
    • Lois, C.1    Hong, E.J.2    Pease, S.3
  • 81
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • Rubinson DA, Dillon CP, Kwiatkowski AV, et al. 2003. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat. Genet. 33:401-6
    • (2003) Nat. Genet. , vol.33 , pp. 401-406
    • Rubinson, D.A.1    Dillon, C.P.2    Kwiatkowski, A.V.3
  • 82
    • 0037021437 scopus 로고    scopus 로고
    • Small interfering RNA and gene silencing in transgenic mice and rats
    • Hasuwa H, Kaseda K, Einarsdottir T, et al. 2002. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett. 532:227-30
    • (2002) FEBS Lett. , vol.532 , pp. 227-230
    • Hasuwa, H.1    Kaseda, K.2    Einarsdottir, T.3
  • 83
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
    • Wiznerowicz M, Trono D. 2003. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J. Virol. 77:8957-61
    • (2003) J. Virol. , vol.77 , pp. 8957-8961
    • Wiznerowicz, M.1    Trono, D.2
  • 84
    • 0346216853 scopus 로고    scopus 로고
    • Local gene knockdown in the brain using viral-mediated RNA interference
    • Hommel JD, Sears RM, Georgescu D, et al. 2003. Local gene knockdown in the brain using viral-mediated RNA interference. Nat. Med. 9:1539-44
    • (2003) Nat. Med. , vol.9 , pp. 1539-1544
    • Hommel, J.D.1    Sears, R.M.2    Georgescu, D.3
  • 85
    • 1242296872 scopus 로고    scopus 로고
    • Inducible, reversible, and stable RNA interference in mammalian cells
    • Gupta S, Schoer RA, Egan JE, et al. 2004. Inducible, reversible, and stable RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA 101:1927-32
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1927-1932
    • Gupta, S.1    Schoer, R.A.2    Egan, J.E.3
  • 86
    • 0037370309 scopus 로고    scopus 로고
    • An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
    • Hemann MT, Fridman JS, Zilfou JT, et al. 2003. An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nat. Genet. 33:396-400
    • (2003) Nat. Genet. , vol.33 , pp. 396-400
    • Hemann, M.T.1    Fridman, J.S.2    Zilfou, J.T.3
  • 87
    • 0036385852 scopus 로고    scopus 로고
    • Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo
    • Bertrand JR, Pottier M, Vekris A, et al. 2002. Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem. Biophys. Res. Commun. 296:1000-4
    • (2002) Biochem. Biophys. Res. Commun. , vol.296 , pp. 1000-1004
    • Bertrand, J.R.1    Pottier, M.2    Vekris, A.3
  • 88
    • 10744219688 scopus 로고    scopus 로고
    • Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
    • Scacheri PC, Rozenblatt-Rosen O, Caplen NJ, et al. 2004. Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc. Natl. Acad. Sci. USA 101:1892-97
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1892-1897
    • Scacheri, P.C.1    Rozenblatt-Rosen, O.2    Caplen, N.J.3
  • 89
    • 4544277478 scopus 로고    scopus 로고
    • Determinants of interferon-stimulated gene induction by RNAi vectors
    • Pebernard S, Iggo RD. 2004. Determinants of interferon-stimulated gene induction by RNAi vectors. Differentiation 72:103-11
    • (2004) Differentiation , vol.72 , pp. 103-111
    • Pebernard, S.1    Iggo, R.D.2
  • 90
    • 2442705429 scopus 로고    scopus 로고
    • Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through Toll-like receptor 3
    • Kariko K, Bhuyan P, Capodici J, et al. 2004. Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through Toll-like receptor 3. J. Immunol. 172:6545-49
    • (2004) J. Immunol. , vol.172 , pp. 6545-6549
    • Kariko, K.1    Bhuyan, P.2    Capodici, J.3
  • 91
    • 0141569812 scopus 로고    scopus 로고
    • Interfering with disease: Opportunities and roadblocks to harnessing RNA interference
    • Lieberman J, Song E, Lee SK, et al. 2003. Interfering with disease: opportunities and roadblocks to harnessing RNA interference. Trends Mol. Med. 9:397-403
    • (2003) Trends Mol. Med. , vol.9 , pp. 397-403
    • Lieberman, J.1    Song, E.2    Lee, S.K.3
  • 92
    • 1242316299 scopus 로고    scopus 로고
    • Molecular medicine for the brain: Silencing of disease genes with RNA interference
    • Davidson BL, Paulson HL. 2004. Molecular medicine for the brain: silencing of disease genes with RNA interference. Lancet Neurol. 3:145-49
    • (2004) Lancet Neurol. , vol.3 , pp. 145-149
    • Davidson, B.L.1    Paulson, H.L.2
  • 93
    • 0036787671 scopus 로고    scopus 로고
    • siRNA-mediated gene silencing in vitro and in vivo
    • Xia H, Mao Q, Paulson HL, et al. 2002. siRNA-mediated gene silencing in vitro and in vivo. Nat. Biotechnol. 20:1006-10
    • (2002) Nat. Biotechnol. , vol.20 , pp. 1006-1010
    • Xia, H.1    Mao, Q.2    Paulson, H.L.3
  • 94
    • 0142084745 scopus 로고    scopus 로고
    • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
    • Hacein-Bey-Abina S, Von Kalle C, Schmidt M, et al. 2003. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302:415-19
    • (2003) Science , vol.302 , pp. 415-419
    • Hacein-Bey-Abina, S.1    Von Kalle, C.2    Schmidt, M.3
  • 95
    • 0344375083 scopus 로고    scopus 로고
    • Lentivirus-delivered stable gene silencing by RNAi in primary cells
    • Stewart SA, Dykxhoorn DM, Palliser D, et al. 2003. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 9:493-501
    • (2003) RNA , vol.9 , pp. 493-501
    • Stewart, S.A.1    Dykxhoorn, D.M.2    Palliser, D.3
  • 96
    • 0037592877 scopus 로고    scopus 로고
    • Insight into the mechanism of the peptide-based gene delivery system MPG: Implications for delivery of siRNA into mammalian cells
    • Simeoni F, Morris MC, Heitz F, et al. 2003. Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells. Nucleic Acids Res. 31:2717-24
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2717-2724
    • Simeoni, F.1    Morris, M.C.2    Heitz, F.3
  • 97
    • 2942530436 scopus 로고    scopus 로고
    • Inhibition of influenza virus production in virus-infected mice by RNA interference
    • Ge Q, Filip L, Bai A, et al. 2004. Inhibition of influenza virus production in virus-infected mice by RNA interference. Proc. Natl. Acad. Sci. USA 101:8676-81
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 8676-8681
    • Ge, Q.1    Filip, L.2    Bai, A.3
  • 98
    • 0041331496 scopus 로고    scopus 로고
    • siRNA function in RNAi: A chemical modification analysis
    • Chiu YL, Rana TM. 2003. siRNA function in RNAi: a chemical modification analysis. RNA 9:1034-48
    • (2003) RNA , vol.9 , pp. 1034-1048
    • Chiu, Y.L.1    Rana, T.M.2
  • 99
    • 1942533474 scopus 로고    scopus 로고
    • In vivo activity of nuclease-resistant siRNAs
    • Layzer JM, McCaffrey AP, Tanner AK, et al. 2004. In vivo activity of nuclease-resistant siRNAs. RNA 10:766-71
    • (2004) RNA , vol.10 , pp. 766-771
    • Layzer, J.M.1    McCaffrey, A.P.2    Tanner, A.K.3
  • 100
    • 0037019339 scopus 로고    scopus 로고
    • RNA interference in adult mice
    • McCaffrey AP, Meuse L, Pham TT, et al. 2002. RNA interference in adult mice. Nature 418:38-39
    • (2002) Nature , vol.418 , pp. 38-39
    • McCaffrey, A.P.1    Meuse, L.2    Pham, T.T.3
  • 101
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis DL, Hagstrom JE, Loomis AG, et al. 2002. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 32:107-8
    • (2002) Nat. Genet. , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3
  • 102
    • 2542561420 scopus 로고    scopus 로고
    • Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer
    • Zhang Y, Zhang YF, Bryant J, et al. 2004. Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer. Clin. Cancer Res. 10:3667-77
    • (2004) Clin. Cancer Res. , vol.10 , pp. 3667-3677
    • Zhang, Y.1    Zhang, Y.F.2    Bryant, J.3
  • 103
    • 0346873025 scopus 로고    scopus 로고
    • Small interfering RNA inhibits hepatitis B virus replication in mice
    • Giladi H, Ketzinel-Gilad M, Rivkin L, et al. 2003. Small interfering RNA inhibits hepatitis B virus replication in mice. Mol. Ther. 8:769-76
    • (2003) Mol. Ther. , vol.8 , pp. 769-776
    • Giladi, H.1    Ketzinel-Gilad, M.2    Rivkin, L.3
  • 104
    • 0038023197 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus in mice by RNA interference
    • McCaffrey AP, Nakai H, Pandey K, et al. 2003. Inhibition of hepatitis B virus in mice by RNA interference. Nat. Biotechnol. 21:639-44
    • (2003) Nat. Biotechnol. , vol.21 , pp. 639-644
    • McCaffrey, A.P.1    Nakai, H.2    Pandey, K.3
  • 106
    • 6944238701 scopus 로고    scopus 로고
    • Small interfering RNA targeting fas protects mice against renal ischemia-reperfusion injury
    • in press
    • Hamar P, Song E, Kokeny G, et al. 2004. Small interfering RNA targeting fas protects mice against renal ischemia-reperfusion injury. Proc. Natl. Acad. Sci. USA in press
    • (2004) Proc. Natl. Acad. Sci. USA
    • Hamar, P.1    Song, E.2    Kokeny, G.3
  • 107
    • 0141552295 scopus 로고    scopus 로고
    • Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    • Sorensen DR, Leirdal M, Sioud M. 2003. Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J. Mol. Biol 327:761-66
    • (2003) J. Mol. Biol. , vol.327 , pp. 761-766
    • Sorensen, D.R.1    Leirdal, M.2    Sioud, M.3
  • 108
    • 0347089037 scopus 로고    scopus 로고
    • Electroporation and RNA interference in the rodent retina in vivo and in vitro
    • Matsuda T, Cepko CL. 2004. Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc. Natl. Acad. Sci. USA 101:16-22
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 16-22
    • Matsuda, T.1    Cepko, C.L.2
  • 109
    • 2442668068 scopus 로고    scopus 로고
    • A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
    • Takei Y, Kadomatsu K, Yuzawa Y, et al. 2004. A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res. 64:3365-70
    • (2004) Cancer Res. , vol.64 , pp. 3365-3370
    • Takei, Y.1    Kadomatsu, K.2    Yuzawa, Y.3
  • 111
    • 10744223373 scopus 로고    scopus 로고
    • Disruption of Ixodes scapularis anticoagulation by using RNA interference
    • Narasimhan S, Montgomery RR, DePonte K, et al. 2004. Disruption of Ixodes scapularis anticoagulation by using RNA interference. Proc. Natl. Acad. Sci. USA 101:1141-46
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1141-1146
    • Narasimhan, S.1    Montgomery, R.R.2    DePonte, K.3
  • 112
    • 0347517725 scopus 로고    scopus 로고
    • Lentiviral vector-mediated delivery of short hairpin RNA results in persistent knockdown of gene expression in mouse brain
    • Van den Haute C, Eggermont K, Nuttin B, et al. 2003. Lentiviral vector-mediated delivery of short hairpin RNA results in persistent knockdown of gene expression in mouse brain. Hum. Gene. Ther. 14:1799-807
    • (2003) Hum. Gene. Ther. , vol.14 , pp. 1799-1807
    • Van Den Haute, C.1    Eggermont, K.2    Nuttin, B.3
  • 113
    • 4043057946 scopus 로고    scopus 로고
    • RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia
    • Xia H, Mao Q, Eliason SL, et al. 2004. RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nat. Med. 10:816-20
    • (2004) Nat. Med. , vol.10 , pp. 816-820
    • Xia, H.1    Mao, Q.2    Eliason, S.L.3
  • 115
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R, Qin Y, Macara IG, et al. 2003. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17:3011-16
    • (2003) Genes Dev. , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.