Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

Genome Research

Volumn 24, Issue 1, 2014, Pages 125-131

  Sung, Young Hoon ^a   Kim, Jong Min ^b   Kim, Hyun Taek ^c   Lee, Jaehoon ^a   Jeon, Jisun ^a   Jin, Young ^a   Choi, Jung Hwa ^c   Ban, Young Ho ^a   Ha, Sang Jun ^a   Kim, Cheol Hee ^c   Lee, Han Woong ^a   Kim, Jin Soo ^b  

^a Yonsei University   (South Korea)

^b Institute for Basic Science   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; GUIDE RNA; MESSENGER RNA; RNA GUIDED ENDONUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; BLASTOCYST; DNA CLEAVAGE; DOUBLE STRANDED DNA BREAK; EMBRYO; GENE INACTIVATION; GENOTYPE; IN VITRO STUDY; INDUCED MUTATION; MOUSE; NEWBORN; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROGENY; SEQUENCE ANALYSIS; SURVIVAL; TRANSGENIC MOUSE; ZEBRA FISH; ZONA PELLUCIDA;

ANIMALS; ANIMALS, NEWBORN; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; EMBRYO, MAMMALIAN; EMBRYO, NONMAMMALIAN; ENDONUCLEASES; FORKHEAD TRANSCRIPTION FACTORS; GENE KNOCKOUT TECHNIQUES; GENOME; GERM-LINE MUTATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MUTAGENESIS; NUCLEAR PROTEINS; PHENOTYPE; RNA, GUIDE; ZEBRAFISH;

EID: 84891704542     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.163394.113     Document Type: Article

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