Small molecule-triggered Cas9 protein with improved genome-editing specificity

Nature Chemical Biology

Volumn 11, Issue 5, 2015, Pages 316-318

  Davis, Kevin M ^a,b   Pattanayak, Vikram ^c   Thompson, David B ^a,b   Zuris, John A ^a,b   Liu, David R ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFIMOXIFENE; BACTERIAL PROTEIN; ENDONUCLEASE; LIGAND; MOLECULAR LIBRARY; TAMOXIFEN;

ANALOGS AND DERIVATIVES; CELL CULTURE; CHEMICAL STRUCTURE; DRUG EFFECTS; GENETICS; GENOME; HEK293 CELL LINE; HIGH THROUGHPUT SEQUENCING; HUMAN; MOLECULAR LIBRARY; PROTEIN CONFORMATION;

BACTERIAL PROTEINS; CELLS, CULTURED; ENDONUCLEASES; GENOME; HEK293 CELLS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN CONFORMATION; SMALL MOLECULE LIBRARIES; TAMOXIFEN;

EID: 84937764361     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1793     Document Type: Article

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