Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

Nature Biotechnology

Volumn 31, Issue 8, 2013, Pages 688-691

  Li, Jian Feng ^a,b   Norville, Julie E ^b,c   Aach, John ^b,c   McCormack, Matthew ^a,b   Zhang, Dandan ^a,b   Bush, Jenifer ^a,b   Church, George M ^b,c   Sheen, Jen ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE GAMMA; DOUBLE STRANDED DNA; GENOMIC DNA; GUIDE RNA; PROCASPASE 9; ZINC FINGER NUCLEASE;

AMPLICON; ARABIDOPSIS THALIANA; BACTERIAL GROWTH; CELL DIVISION; GENE REPLACEMENT THERAPY; GENETIC ENGINEERING; GENETIC RECOMBINATION; HUMAN; LETTER; MUTAGENESIS; NICOTIANA BENTHAMIANA; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTOPLAST; SEQUENCE ANALYSIS;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; BASE SEQUENCE; CASPASE 9; ESCHERICHIA COLI; GENETIC ENGINEERING; GENOME, PLANT; HOMOLOGOUS RECOMBINATION; OXIDOREDUCTASES; PROTEIN KINASES; RNA; TOBACCO;

EID: 84883785822     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2654     Document Type: Letter

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