-
1
-
-
79952278792
-
Generation of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos
-
Artus J., Hadjantonakis A.K. Generation of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos. Methods Mol. Biol. 2011, 693:37-56.
-
(2011)
Methods Mol. Biol.
, vol.693
, pp. 37-56
-
-
Artus, J.1
Hadjantonakis, A.K.2
-
2
-
-
84885620722
-
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
-
Bauer D.E., Kamran S.C., Lessard S., Xu J., Fujiwara Y., Lin C., Shao Z., Canver M.C., Smith E.C., Pinello L., et al. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science 2013, 342:253-257.
-
(2013)
Science
, vol.342
, pp. 253-257
-
-
Bauer, D.E.1
Kamran, S.C.2
Lessard, S.3
Xu, J.4
Fujiwara, Y.5
Lin, C.6
Shao, Z.7
Canver, M.C.8
Smith, E.C.9
Pinello, L.10
-
3
-
-
84905388288
-
Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells
-
Canver M.C., Bauer D.E., Dass A., Yien Y.Y., Chung J., Masuda T., Maeda T., Paw B.H., Orkin S.H. Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells. J.Biol. Chem. 2014, 289:21312-21324.
-
(2014)
J.Biol. Chem.
, vol.289
, pp. 21312-21324
-
-
Canver, M.C.1
Bauer, D.E.2
Dass, A.3
Yien, Y.Y.4
Chung, J.5
Masuda, T.6
Maeda, T.7
Paw, B.H.8
Orkin, S.H.9
-
4
-
-
84874624936
-
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
-
Cho S.W., Kim S., Kim J.M., Kim J.S. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat. Biotechnol. 2013, 31:230-232.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 230-232
-
-
Cho, S.W.1
Kim, S.2
Kim, J.M.3
Kim, J.S.4
-
5
-
-
84899490344
-
Targeted genomic rearrangements using CRISPR/Cas technology
-
Choi P.S., Meyerson M. Targeted genomic rearrangements using CRISPR/Cas technology. Nat. Commun. 2014, 5:3728.
-
(2014)
Nat. Commun.
, vol.5
, pp. 3728
-
-
Choi, P.S.1
Meyerson, M.2
-
6
-
-
13144259630
-
EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract
-
Dottori M., Hartley L., Galea M., Paxinos G., Polizzotto M., Kilpatrick T., Bartlett P.F., Murphy M., Köntgen F., Boyd A.W. EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract. Proc. Natl. Acad. Sci. USA 1998, 95:13248-13253.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13248-13253
-
-
Dottori, M.1
Hartley, L.2
Galea, M.3
Paxinos, G.4
Polizzotto, M.5
Kilpatrick, T.6
Bartlett, P.F.7
Murphy, M.8
Köntgen, F.9
Boyd, A.W.10
-
7
-
-
34248366984
-
Developmental and adult phenotyping directly from mutant embryonic stem cells
-
George S.H., Gertsenstein M., Vintersten K., Korets-Smith E., Murphy J., Stevens M.E., Haigh J.J., Nagy A. Developmental and adult phenotyping directly from mutant embryonic stem cells. Proc. Natl. Acad. Sci. USA 2007, 104:4455-4460.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4455-4460
-
-
George, S.H.1
Gertsenstein, M.2
Vintersten, K.3
Korets-Smith, E.4
Murphy, J.5
Stevens, M.E.6
Haigh, J.J.7
Nagy, A.8
-
8
-
-
84878731165
-
Targeted chromosomal deletions and inversions in zebrafish
-
Gupta A., Hall V.L., Kok F.O., Shin M., McNulty J.C., Lawson N.D., Wolfe S.A. Targeted chromosomal deletions and inversions in zebrafish. Genome Res. 2013, 23:1008-1017.
-
(2013)
Genome Res.
, vol.23
, pp. 1008-1017
-
-
Gupta, A.1
Hall, V.L.2
Kok, F.O.3
Shin, M.4
McNulty, J.C.5
Lawson, N.D.6
Wolfe, S.A.7
-
9
-
-
0031770816
-
Engineering chromosomes in mice through targeted meiotic recombination (TAMERE)
-
Hérault Y., Rassoulzadegan M., Cuzin F., Duboule D. Engineering chromosomes in mice through targeted meiotic recombination (TAMERE). Nat. Genet. 1998, 20:381-384.
-
(1998)
Nat. Genet.
, vol.20
, pp. 381-384
-
-
Hérault, Y.1
Rassoulzadegan, M.2
Cuzin, F.3
Duboule, D.4
-
10
-
-
84902096048
-
Development and applications of CRISPR-Cas9 for genome engineering
-
Hsu P.D., Lander E.S., Zhang F. Development and applications of CRISPR-Cas9 for genome engineering. Cell 2014, 157:1262-1278.
-
(2014)
Cell
, vol.157
, pp. 1262-1278
-
-
Hsu, P.D.1
Lander, E.S.2
Zhang, F.3
-
11
-
-
84903545084
-
Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
-
Kuscu C., Arslan S., Singh R., Thorpe J., Adli M. Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease. Nat. Biotechnol. 2014, 32:677-683.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 677-683
-
-
Kuscu, C.1
Arslan, S.2
Singh, R.3
Thorpe, J.4
Adli, M.5
-
12
-
-
84863275797
-
Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases
-
Lee H.J., Kweon J., Kim E., Kim S., Kim J.S. Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases. Genome Res. 2012, 22:539-548.
-
(2012)
Genome Res.
, vol.22
, pp. 539-548
-
-
Lee, H.J.1
Kweon, J.2
Kim, E.3
Kim, S.4
Kim, J.S.5
-
13
-
-
0030050159
-
LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias
-
Ma C., Staudt L.M. LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias. Blood 1996, 87:734-745.
-
(1996)
Blood
, vol.87
, pp. 734-745
-
-
Ma, C.1
Staudt, L.M.2
-
14
-
-
84875249885
-
An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape
-
Marinić M., Aktas T., Ruf S., Spitz F. An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape. Dev. Cell 2013, 24:530-542.
-
(2013)
Dev. Cell
, vol.24
, pp. 530-542
-
-
Marinić, M.1
Aktas, T.2
Ruf, S.3
Spitz, F.4
-
15
-
-
84874415687
-
Impact of copy number variations (CNVs) on long-range gene regulation at the HoxD locus
-
Montavon T., Thevenet L., Duboule D. Impact of copy number variations (CNVs) on long-range gene regulation at the HoxD locus. Proc. Natl. Acad. Sci. USA 2012, 109:20204-20211.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 20204-20211
-
-
Montavon, T.1
Thevenet, L.2
Duboule, D.3
-
16
-
-
0033655437
-
Skeletal morphogenesis
-
Mundlos S. Skeletal morphogenesis. Methods Mol. Biol. 2000, 136:61-70.
-
(2000)
Methods Mol. Biol.
, vol.136
, pp. 61-70
-
-
Mundlos, S.1
-
17
-
-
84908031939
-
Making designer mutants in model organisms
-
Peng Y., Clark K.J., Campbell J.M., Panetta M.R., Guo Y., Ekker S.C. Making designer mutants in model organisms. Development 2014, 141:4042-4054.
-
(2014)
Development
, vol.141
, pp. 4042-4054
-
-
Peng, Y.1
Clark, K.J.2
Campbell, J.M.3
Panetta, M.R.4
Guo, Y.5
Ekker, S.C.6
-
18
-
-
79953176250
-
Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor
-
Ruf S., Symmons O., Uslu V.V., Dolle D., Hot C., Ettwiller L., Spitz F. Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat. Genet. 2011, 43:379-386.
-
(2011)
Nat. Genet.
, vol.43
, pp. 379-386
-
-
Ruf, S.1
Symmons, O.2
Uslu, V.V.3
Dolle, D.4
Hot, C.5
Ettwiller, L.6
Spitz, F.7
-
19
-
-
84877917486
-
Structural variations, the regulatory landscape of the genome and their alteration in human disease
-
Spielmann M., Mundlos S. Structural variations, the regulatory landscape of the genome and their alteration in human disease. BioEssays 2013, 35:533-543.
-
(2013)
BioEssays
, vol.35
, pp. 533-543
-
-
Spielmann, M.1
Mundlos, S.2
-
20
-
-
84867276487
-
Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus
-
Spielmann M., Brancati F., Krawitz P.M., Robinson P.N., Ibrahim D.M., Franke M., Hecht J., Lohan S., Dathe K., Nardone A.M., et al. Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus. Am. J. Hum. Genet. 2012, 91:629-635.
-
(2012)
Am. J. Hum. Genet.
, vol.91
, pp. 629-635
-
-
Spielmann, M.1
Brancati, F.2
Krawitz, P.M.3
Robinson, P.N.4
Ibrahim, D.M.5
Franke, M.6
Hecht, J.7
Lohan, S.8
Dathe, K.9
Nardone, A.M.10
-
21
-
-
23044477774
-
Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes
-
Spitz F., Herkenne C., Morris M.A., Duboule D. Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nat. Genet. 2005, 37:889-893.
-
(2005)
Nat. Genet.
, vol.37
, pp. 889-893
-
-
Spitz, F.1
Herkenne, C.2
Morris, M.A.3
Duboule, D.4
-
22
-
-
77949831756
-
Structural variation in the human genome and its role in disease
-
Stankiewicz P., Lupski J.R. Structural variation in the human genome and its role in disease. Annu. Rev. Med. 2010, 61:437-455.
-
(2010)
Annu. Rev. Med.
, vol.61
, pp. 437-455
-
-
Stankiewicz, P.1
Lupski, J.R.2
-
23
-
-
56749185760
-
Triangular tibia with fibular aplasia associated with a microdeletion on 2q11.2 encompassing LAF4
-
Steichen-Gersdorf E., Gassner I., Superti-Furga A., Ullmann R., Stricker S., Klopocki E., Mundlos S. Triangular tibia with fibular aplasia associated with a microdeletion on 2q11.2 encompassing LAF4. Clin. Genet. 2008, 74:560-565.
-
(2008)
Clin. Genet.
, vol.74
, pp. 560-565
-
-
Steichen-Gersdorf, E.1
Gassner, I.2
Superti-Furga, A.3
Ullmann, R.4
Stricker, S.5
Klopocki, E.6
Mundlos, S.7
-
24
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang H., Yang H., Shivalila C.S., Dawlaty M.M., Cheng A.W., Zhang F., Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 2013, 153:910-918.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
25
-
-
84880117972
-
Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish
-
Xiao A., Wang Z., Hu Y., Wu Y., Luo Z., Yang Z., Zu Y., Li W., Huang P., Tong X., et al. Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic Acids Res. 2013, 41:e141.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. e141
-
-
Xiao, A.1
Wang, Z.2
Hu, Y.3
Wu, Y.4
Luo, Z.5
Yang, Z.6
Zu, Y.7
Li, W.8
Huang, P.9
Tong, X.10
|