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Volumn 8, Issue 2, 2007, Pages 104-115

Dynamic genome architecture in the nuclear space: Regulation of gene expression in three dimensions

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EID: 33846283384     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg2041     Document Type: Review
Times cited : (663)

References (102)
  • 2
    • 30444437477 scopus 로고    scopus 로고
    • Subnuclear organelles: New insights into form and function
    • Handwerger, K. E. & Gall, J. G. Subnuclear organelles: new insights into form and function. Trends Cell Biol. 16, 19-26 (2006).
    • (2006) Trends Cell Biol , vol.16 , pp. 19-26
    • Handwerger, K.E.1    Gall, J.G.2
  • 3
    • 30044434446 scopus 로고    scopus 로고
    • Nucleolus: From structure to dynamics
    • Hernandez-Verdun, D. Nucleolus: from structure to dynamics. Histochem. Cell Biol. 125, 127-137 (2006).
    • (2006) Histochem. Cell Biol , vol.125 , pp. 127-137
    • Hernandez-Verdun, D.1
  • 4
    • 0041669439 scopus 로고    scopus 로고
    • Nuclear speckles: A model for nuclear organelles
    • Lamond, A. I. & Spector, D. L. Nuclear speckles: a model for nuclear organelles. Nature Rev. Mol. Cell Biol. 4, 605-612 (2003).
    • (2003) Nature Rev. Mol. Cell Biol , vol.4 , pp. 605-612
    • Lamond, A.I.1    Spector, D.L.2
  • 5
    • 0029973080 scopus 로고    scopus 로고
    • Active RNA polymerases are localized within discrete transcription 'factories' in human nuclei
    • Iborra, F. J., Pombo, A., Jackson, D. A. & Cook, P. R. Active RNA polymerases are localized within discrete transcription 'factories' in human nuclei. J. Cell Sci. 109, 1427-1436 (1996).
    • (1996) J. Cell Sci , vol.109 , pp. 1427-1436
    • Iborra, F.J.1    Pombo, A.2    Jackson, D.A.3    Cook, P.R.4
  • 6
    • 0029328590 scopus 로고
    • Nuclear organization: Uniting replication foci, chromatin domains and chromosome structure
    • Jackson, D. A. Nuclear organization: uniting replication foci, chromatin domains and chromosome structure. BioEssays 17, 587-591 (1995).
    • (1995) BioEssays , vol.17 , pp. 587-591
    • Jackson, D.A.1
  • 7
    • 33646856965 scopus 로고    scopus 로고
    • Chromosomal distribution of PcG proteins during Drosophila development
    • Negre, N. et al. Chromosomal distribution of PcG proteins during Drosophila development. PLoS Biol. 4, e170 (2006).
    • (2006) PLoS Biol , vol.4
    • Negre, N.1
  • 8
    • 33744948540 scopus 로고    scopus 로고
    • Nuclear architecture in the light of gene expression and cell differentiation studies
    • Bartova, E. & Kozubek, S. Nuclear architecture in the light of gene expression and cell differentiation studies. Biol. Cell 98, 323-336 (2006).
    • (2006) Biol. Cell , vol.98 , pp. 323-336
    • Bartova, E.1    Kozubek, S.2
  • 9
    • 0035316574 scopus 로고    scopus 로고
    • Chromosome territories, nuclear architecture and gene regulation in mammalian cells
    • Cremer, T. & Cremer, C. Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nature Rev. Genet. 2, 292-301 (2001).
    • (2001) Nature Rev. Genet , vol.2 , pp. 292-301
    • Cremer, T.1    Cremer, C.2
  • 10
    • 27844495137 scopus 로고    scopus 로고
    • The genome and the nucleus: A marriage made by evolution. Genome organisation and nuclear architecture
    • Foster, H. A. & Bridger, J. M. The genome and the nucleus: a marriage made by evolution. Genome organisation and nuclear architecture. Chromosoma 114, 212-229 (2005).
    • (2005) Chromosoma , vol.114 , pp. 212-229
    • Foster, H.A.1    Bridger, J.M.2
  • 11
    • 2942679507 scopus 로고    scopus 로고
    • Form follows function: The genomic organization of cellular differentiation
    • Kosak, S. T. & Groudine, M. Form follows function: the genomic organization of cellular differentiation. Genes Dev. 18, 1371-1384 (2004).
    • (2004) Genes Dev , vol.18 , pp. 1371-1384
    • Kosak, S.T.1    Groudine, M.2
  • 12
    • 1442288553 scopus 로고    scopus 로고
    • The spatial organization of the genome in mammalian cells
    • Pederson, T. The spatial organization of the genome in mammalian cells. Curr. Opin. Genet. Dev. 14, 203-209 (2004).
    • (2004) Curr. Opin. Genet. Dev , vol.14 , pp. 203-209
    • Pederson, T.1
  • 14
    • 21844444077 scopus 로고    scopus 로고
    • Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes
    • Bolzer, A. et al. Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol. 3, e157 (2005).
    • (2005) PLoS Biol , vol.3
    • Bolzer, A.1
  • 15
    • 33646526019 scopus 로고    scopus 로고
    • Chromosome territories - a functional nuclear landscape
    • Cremer, T. et al. Chromosome territories - a functional nuclear landscape. Curr. Opin. Cell Biol. 18, 307-316 (2006).
    • (2006) Curr. Opin. Cell Biol , vol.18 , pp. 307-316
    • Cremer, T.1
  • 16
    • 0033553877 scopus 로고    scopus 로고
    • Differences in the localization and morphology of chromosomes in the human nucleus
    • Croft, J. A. et al. Differences in the localization and morphology of chromosomes in the human nucleus. J. Cell Biol. 145, 1119-1131 (1999).
    • (1999) J. Cell Biol , vol.145 , pp. 1119-1131
    • Croft, J.A.1
  • 18
    • 0031954055 scopus 로고    scopus 로고
    • Structure and dynamics of human interphase chromosome territories in vivo
    • Zink, D. et al. Structure and dynamics of human interphase chromosome territories in vivo. Hum. Genet. 102, 241-251 (1998).
    • (1998) Hum. Genet , vol.102 , pp. 241-251
    • Zink, D.1
  • 19
    • 0037007044 scopus 로고    scopus 로고
    • Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates
    • Tanabe, H. et al. Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates. Proc. Natl Acad. Sci. USA 99, 4424-4429 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 4424-4429
    • Tanabe, H.1
  • 20
    • 0041885232 scopus 로고    scopus 로고
    • Inheritance of gene density-related higher order chromatin arrangements in normal and tumor cell nuclei
    • Cremer, M. et al. Inheritance of gene density-related higher order chromatin arrangements in normal and tumor cell nuclei. J. Cell Biol. 162, 809-820 (2003).
    • (2003) J. Cell Biol , vol.162 , pp. 809-820
    • Cremer, M.1
  • 21
    • 0037165965 scopus 로고    scopus 로고
    • Visualizing chromatin dynamics in interphase nuclei
    • Gasser, S. M. Visualizing chromatin dynamics in interphase nuclei. Science 296, 1412-1416 (2002).
    • (2002) Science , vol.296 , pp. 1412-1416
    • Gasser, S.M.1
  • 22
    • 0031009827 scopus 로고    scopus 로고
    • Chromatin dynamics in interphase nuclei and its implications for nuclear structure
    • Abney, J. R., Cutler, B., Fillbach, M. L., Axelrod, D. & Scalettar, B. A. Chromatin dynamics in interphase nuclei and its implications for nuclear structure. J. Cell Biol. 137, 1459-1468 (1997).
    • (1997) J. Cell Biol , vol.137 , pp. 1459-1468
    • Abney, J.R.1    Cutler, B.2    Fillbach, M.L.3    Axelrod, D.4    Scalettar, B.A.5
  • 23
    • 0345039879 scopus 로고    scopus 로고
    • Global chromosome positions are transmitted through mitosis in mammalian cells
    • Gerlich, D. et al. Global chromosome positions are transmitted through mitosis in mammalian cells. Cell 112, 751-764 (2003).
    • (2003) Cell , vol.112 , pp. 751-764
    • Gerlich, D.1
  • 24
    • 0037416135 scopus 로고    scopus 로고
    • Walter, J., Schermelleh, L., Cremer, M., Tashiro, S. & Cremer, T. Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages. J. Cell Biol. 160, 685-697 (2003). This work reports that chromatin mobility is increased during early G1. It also shows that the arrangement of chromosome neighbourhoods is not retained during mitosis.
    • Walter, J., Schermelleh, L., Cremer, M., Tashiro, S. & Cremer, T. Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages. J. Cell Biol. 160, 685-697 (2003). This work reports that chromatin mobility is increased during early G1. It also shows that the arrangement of chromosome neighbourhoods is not retained during mitosis.
  • 25
    • 0031457326 scopus 로고    scopus 로고
    • Marshall, W. F. et al. Interphase chromosomes undergo constrained diffusional motion in living cells. Curr. Biol. 7, 930-939 (1997). The initial report that showed constraint diffusion of chromatin in yeast and D. melanogaster.
    • Marshall, W. F. et al. Interphase chromosomes undergo constrained diffusional motion in living cells. Curr. Biol. 7, 930-939 (1997). The initial report that showed constraint diffusion of chromatin in yeast and D. melanogaster.
  • 26
    • 0036006293 scopus 로고    scopus 로고
    • Chromatin motion is constrained by association with nuclear compartments in human cells
    • Chubb, J. R., Boyle, S., Perry, P. & Bickmore, W. A. Chromatin motion is constrained by association with nuclear compartments in human cells. Curr. Biol. 12, 439-445 (2002).
    • (2002) Curr. Biol , vol.12 , pp. 439-445
    • Chubb, J.R.1    Boyle, S.2    Perry, P.3    Bickmore, W.A.4
  • 27
    • 0038010498 scopus 로고    scopus 로고
    • Chromatin of endoreduplicated pavement cells has greater range of movement than that of diploid guard cells in Arabidopsis thaliana
    • Kato, N. & Lam, E. Chromatin of endoreduplicated pavement cells has greater range of movement than that of diploid guard cells in Arabidopsis thaliana. J. Cell Sci. 116, 2195-2201 (2003).
    • (2003) J. Cell Sci , vol.116 , pp. 2195-2201
    • Kato, N.1    Lam, E.2
  • 28
    • 33645001905 scopus 로고    scopus 로고
    • Use of two-color fluorescence-tagged transgenes to study interphase chromosomes in living plants
    • Matzke, A. J., Huettel, B., van der Winden, J. & Matzke, M. Use of two-color fluorescence-tagged transgenes to study interphase chromosomes in living plants. Plant Physiol. 139, 1586-1596 (2005).
    • (2005) Plant Physiol , vol.139 , pp. 1586-1596
    • Matzke, A.J.1    Huettel, B.2    van der Winden, J.3    Matzke, M.4
  • 29
    • 0035928736 scopus 로고    scopus 로고
    • Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus
    • Vazquez, J., Belmont, A. S. & Sedat, J. W. Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr. Biol. 11, 1227-1239 (2001).
    • (2001) Curr. Biol , vol.11 , pp. 1227-1239
    • Vazquez, J.1    Belmont, A.S.2    Sedat, J.W.3
  • 30
    • 1142281997 scopus 로고    scopus 로고
    • The radial positioning of chromatin is not inherited through mitosis but is established de novo in early G1
    • Thomson, I., Gilchrist, S., Bickmore, W. A. & Chubb, J. R. The radial positioning of chromatin is not inherited through mitosis but is established de novo in early G1. Curr. Biol. 14, 166-172 (2004).
    • (2004) Curr. Biol , vol.14 , pp. 166-172
    • Thomson, I.1    Gilchrist, S.2    Bickmore, W.A.3    Chubb, J.R.4
  • 31
    • 28444496753 scopus 로고    scopus 로고
    • Levi, V., Ruan, Q., Plutz, M., Belmont, A. S. & Gratton, E. Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope. Biophys. J. 89, 4275-4285 (2005). An analysis of chromatin dynamics at high spatial and temporal resolution shows that constrained diffusive movement is interspersed by small-scale, energy-dependent jumps.
    • Levi, V., Ruan, Q., Plutz, M., Belmont, A. S. & Gratton, E. Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope. Biophys. J. 89, 4275-4285 (2005). An analysis of chromatin dynamics at high spatial and temporal resolution shows that constrained diffusive movement is interspersed by small-scale, energy-dependent jumps.
  • 32
    • 33751258576 scopus 로고    scopus 로고
    • Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks
    • Albiez, H. et al. Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks. Chromosome Res. 14, 707-733 (2006).
    • (2006) Chromosome Res , vol.14 , pp. 707-733
    • Albiez, H.1
  • 33
    • 0034065032 scopus 로고    scopus 로고
    • Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei
    • Volpi, E. V. et al. Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei. J. Cell Sci. 113, 1565-1576 (2000).
    • (2000) J. Cell Sci , vol.113 , pp. 1565-1576
    • Volpi, E.V.1
  • 34
    • 0036061468 scopus 로고    scopus 로고
    • Subchromosomal positioning of the epidermal differentiation complex (EDC) in keratinocyte and lymphoblast interphase nuclei
    • Williams, R. R., Broad, S., Sheer, D. & Ragoussis, J. Subchromosomal positioning of the epidermal differentiation complex (EDC) in keratinocyte and lymphoblast interphase nuclei. Exp. Cell Res. 272, 163-175 (2002).
    • (2002) Exp. Cell Res , vol.272 , pp. 163-175
    • Williams, R.R.1    Broad, S.2    Sheer, D.3    Ragoussis, J.4
  • 35
    • 33646729244 scopus 로고    scopus 로고
    • Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations
    • Branco, M. R. & Pombo, A. Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations. PLoS Biol. 4, e138 (2006).
    • (2006) PLoS Biol , vol.4
    • Branco, M.R.1    Pombo, A.2
  • 36
    • 0035150980 scopus 로고    scopus 로고
    • Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator
    • Tumbar, T. & Belmont, A. S. Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator. Nature Cell Biol. 3, 134-139 (2001).
    • (2001) Nature Cell Biol , vol.3 , pp. 134-139
    • Tumbar, T.1    Belmont, A.S.2
  • 37
    • 12844272896 scopus 로고    scopus 로고
    • Common effects of acidic activators on large-scale chromatin structure and transcription
    • Carpenter, A. E., Memedula, S., Plutz, M. J. & Belmont, A. S. Common effects of acidic activators on large-scale chromatin structure and transcription. Mol. Cell. Biol. 25, 958-968 (2005).
    • (2005) Mol. Cell. Biol , vol.25 , pp. 958-968
    • Carpenter, A.E.1    Memedula, S.2    Plutz, M.J.3    Belmont, A.S.4
  • 38
    • 33646021963 scopus 로고    scopus 로고
    • Long-range directional movement of an interphase chromosome site
    • This work reports that a transgenic array of lac operators undergoes directed movement following transcriptional activation with a lac-repressor-VP16 fusion protein
    • Chuang, C. H. et al. Long-range directional movement of an interphase chromosome site. Curr. Biol. 16, 825-831 (2006). This work reports that a transgenic array of lac operators undergoes directed movement following transcriptional activation with a lac-repressor-VP16 fusion protein.
    • (2006) Curr. Biol , vol.16 , pp. 825-831
    • Chuang, C.H.1
  • 39
    • 0037023361 scopus 로고    scopus 로고
    • Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development
    • Kosak, S. T. et al. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 296, 158-162 (2002).
    • (2002) Science , vol.296 , pp. 158-162
    • Kosak, S.T.1
  • 40
    • 10944261946 scopus 로고    scopus 로고
    • Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation
    • Hewitt, S. L., High, F. A., Reiner, S. L., Fisher, A. G. & Merkenschlager, M. Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation. Eur. J. Immunol. 34, 3604-3613 (2004).
    • (2004) Eur. J. Immunol , vol.34 , pp. 3604-3613
    • Hewitt, S.L.1    High, F.A.2    Reiner, S.L.3    Fisher, A.G.4    Merkenschlager, M.5
  • 41
    • 31644436473 scopus 로고    scopus 로고
    • Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus
    • Williams, R. R. et al. Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus. J. Cell Sci. 119, 132-140 (2006).
    • (2006) J. Cell Sci , vol.119 , pp. 132-140
    • Williams, R.R.1
  • 42
    • 4544255977 scopus 로고    scopus 로고
    • Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei
    • Zink, D. et al. Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei. J. Cell Biol. 166, 815-825 (2004).
    • (2004) J. Cell Biol , vol.166 , pp. 815-825
    • Zink, D.1
  • 43
    • 33744779614 scopus 로고    scopus 로고
    • The locus control region is required for association of the murine β-globin locus with engaged transcription factories during erythroid maturation
    • Ragoczy, T., Bender, M. A., Telling, A., Byron, R. & Groudine, M. The locus control region is required for association of the murine β-globin locus with engaged transcription factories during erythroid maturation. Genes Dev. 20, 1447-1457 (2006).
    • (2006) Genes Dev , vol.20 , pp. 1447-1457
    • Ragoczy, T.1    Bender, M.A.2    Telling, A.3    Byron, R.4    Groudine, M.5
  • 44
    • 0032490917 scopus 로고    scopus 로고
    • Perinuclear localization of chromatin facilitates transcriptional silencing
    • Andrulis, E. D., Neiman, A. M., Zappulla, D. C. & Sternglanz, R. Perinuclear localization of chromatin facilitates transcriptional silencing. Nature 394, 592-595 (1998).
    • (1998) Nature , vol.394 , pp. 592-595
    • Andrulis, E.D.1    Neiman, A.M.2    Zappulla, D.C.3    Sternglanz, R.4
  • 45
    • 2342501365 scopus 로고    scopus 로고
    • Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization
    • Casolari, J. M. et al. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell 117, 427-439 (2004).
    • (2004) Cell , vol.117 , pp. 427-439
    • Casolari, J.M.1
  • 46
    • 31544471808 scopus 로고    scopus 로고
    • Nup-PI: The nucleopore-promoter interaction of genes in yeast
    • Schmid, M. et al. Nup-PI: the nucleopore-promoter interaction of genes in yeast. Mol. Cell 21, 379-391 (2006).
    • (2006) Mol. Cell , vol.21 , pp. 379-391
    • Schmid, M.1
  • 47
    • 14044266853 scopus 로고    scopus 로고
    • Gene recruitment of the activated INO1 locus to the nuclear membrane
    • Brickner, J. H. & Walter, P. Gene recruitment of the activated INO1 locus to the nuclear membrane. PLoS Biol. 2, e342 (2004).
    • (2004) PLoS Biol , vol.2
    • Brickner, J.H.1    Walter, P.2
  • 48
    • 17644419993 scopus 로고    scopus 로고
    • Reverse recruitment: The Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation
    • Menon, B. B. et al. Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc. Natl Acad. Sci. USA 102, 5749-5754 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 5749-5754
    • Menon, B.B.1
  • 49
    • 33745699154 scopus 로고    scopus 로고
    • Motion as a phenotype: The use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics
    • Drubin, D. A., Garakani, A. M. & Silver, P. A. Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics. BMC Cell Biol. 7, 19 (2006).
    • (2006) BMC Cell Biol , vol.7 , pp. 19
    • Drubin, D.A.1    Garakani, A.M.2    Silver, P.A.3
  • 50
    • 33745001795 scopus 로고    scopus 로고
    • SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope
    • Cabal, G. G. et al. SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope. Nature 441, 770-773 (2006).
    • (2006) Nature , vol.441 , pp. 770-773
    • Cabal, G.G.1
  • 51
    • 33744977019 scopus 로고    scopus 로고
    • Taddei, A. et al. Nuclear pore association confers optimal expression levels for an inducible yeast gene. Nature 441, 774-778 (2006). References 49-51 show that, as a result of increased tethering to the nuclear pores, the mobility of yeast loci becomes constrained alongside the nuclear envelope following transcriptional activation.
    • Taddei, A. et al. Nuclear pore association confers optimal expression levels for an inducible yeast gene. Nature 441, 774-778 (2006). References 49-51 show that, as a result of increased tethering to the nuclear pores, the mobility of yeast loci becomes constrained alongside the nuclear envelope following transcriptional activation.
  • 52
    • 0344338368 scopus 로고
    • Gene gating: A hypothesis
    • Blobel, G. Gene gating: a hypothesis. Proc. Natl Acad. Sci. USA 82, 8527-8529 (1985).
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 8527-8529
    • Blobel, G.1
  • 53
    • 0031437119 scopus 로고    scopus 로고
    • Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin
    • Brown, K. E. et al. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell 91, 845-854 (1997).
    • (1997) Cell , vol.91 , pp. 845-854
    • Brown, K.E.1
  • 54
    • 33644631504 scopus 로고    scopus 로고
    • The end adjusts the means: Heterochromatin remodelling during terminal cell differentiation
    • Grigoryev, S. A., Bulynko, Y. A. & Popova, E. Y. The end adjusts the means: heterochromatin remodelling during terminal cell differentiation. Chromosome Res. 14, 53-69 (2006).
    • (2006) Chromosome Res , vol.14 , pp. 53-69
    • Grigoryev, S.A.1    Bulynko, Y.A.2    Popova, E.Y.3
  • 55
    • 10644289346 scopus 로고    scopus 로고
    • Dynamic repositioning of CD4 and CD8 genes during T cell development
    • Delaire, S., Huang, Y. H., Chan, S. W. & Robey, E. A. Dynamic repositioning of CD4 and CD8 genes during T cell development. J. Exp. Med. 200, 1427-1435 (2004).
    • (2004) J. Exp. Med , vol.200 , pp. 1427-1435
    • Delaire, S.1    Huang, Y.H.2    Chan, S.W.3    Robey, E.A.4
  • 56
    • 0033083793 scopus 로고    scopus 로고
    • Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division
    • Brown, K. E., Baxter, J., Graf, D., Merkenschlager, M. & Fisher, A. G. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Mol. Cell 3, 207-217 (1999).
    • (1999) Mol. Cell , vol.3 , pp. 207-217
    • Brown, K.E.1    Baxter, J.2    Graf, D.3    Merkenschlager, M.4    Fisher, A.G.5
  • 57
    • 0029937208 scopus 로고    scopus 로고
    • Genetic modification of heterochromatic association and nuclear organization in Drosophila
    • Csink, A. K. & Henikoff, S. Genetic modification of heterochromatic association and nuclear organization in Drosophila. Nature 381, 529-531 (1996).
    • (1996) Nature , vol.381 , pp. 529-531
    • Csink, A.K.1    Henikoff, S.2
  • 58
    • 0029943141 scopus 로고    scopus 로고
    • Perturbation of nuclear architecture by long-distance chromosome interactions
    • Dernburg, A. F. et al. Perturbation of nuclear architecture by long-distance chromosome interactions. Cell 85, 745-759 (1996).
    • (1996) Cell , vol.85 , pp. 745-759
    • Dernburg, A.F.1
  • 59
    • 18044364584 scopus 로고    scopus 로고
    • Harmon, B. & Sedat, J. Cell-by-cell dissection of gene expression and chromosomal interactions reveals consequences of nuclear reorganization. PLoS Biol. 3, e67 (2005). This study examines the expression state of a chromosomal locus and its interaction with heterochromatin. The authors suggest that the extent of chromatin tethering, and therefore mobility, has an important role in gene regulation
    • Harmon, B. & Sedat, J. Cell-by-cell dissection of gene expression and chromosomal interactions reveals consequences of nuclear reorganization. PLoS Biol. 3, e67 (2005). This study examines the expression state of a chromosomal locus and its interaction with heterochromatin. The authors suggest that the extent of chromatin tethering, and therefore mobility, has an important role in gene regulation
  • 60
    • 0034976421 scopus 로고    scopus 로고
    • Expression of α- and β-globin genes occurs within different nuclear domains in haemopoietic cells
    • Brown, K. E. et al. Expression of α- and β-globin genes occurs within different nuclear domains in haemopoietic cells. Nature Cell Biol. 3, 602-606 (2001).
    • (2001) Nature Cell Biol , vol.3 , pp. 602-606
    • Brown, K.E.1
  • 61
    • 16844385848 scopus 로고    scopus 로고
    • Thakar, R. & Csink, A. K. Changing chromatin dynamics and nuclear organization during differentiation in Drosophila larval tissue. J. Cell Sci. 118, 951-960 (2005). Living cell measurements show that, despite similar diffusion coefficients, chromatin mobility is more constrained in the nuclei of differentiated cells of the D. melanogaster eye imaginal disc than in the nuclei of undifferentiated counterparts.
    • Thakar, R. & Csink, A. K. Changing chromatin dynamics and nuclear organization during differentiation in Drosophila larval tissue. J. Cell Sci. 118, 951-960 (2005). Living cell measurements show that, despite similar diffusion coefficients, chromatin mobility is more constrained in the nuclei of differentiated cells of the D. melanogaster eye imaginal disc than in the nuclei of undifferentiated counterparts.
  • 62
    • 0032487506 scopus 로고    scopus 로고
    • Large-scale chromosomal movements during interphase progression in Drosophila
    • Csink, A. K. & Henikoff, S. Large-scale chromosomal movements during interphase progression in Drosophila. J. Cell Biol. 143, 13-22 (1998).
    • (1998) J. Cell Biol , vol.143 , pp. 13-22
    • Csink, A.K.1    Henikoff, S.2
  • 63
    • 28344440877 scopus 로고    scopus 로고
    • Mitotic remodeling of the replicon and chromosome structure
    • Lemaitre, J. M., Danis, E., Pasero, P., Vassetzky, Y. & Mechali, M. Mitotic remodeling of the replicon and chromosome structure. Cell 123, 787-801 (2005).
    • (2005) Cell , vol.123 , pp. 787-801
    • Lemaitre, J.M.1    Danis, E.2    Pasero, P.3    Vassetzky, Y.4    Mechali, M.5
  • 64
    • 0026763535 scopus 로고
    • Rearrangement of centromeric satellite DNA in hippocampal neurons exhibiting long-term potentiation
    • Billia, F., Baskys, A., Carlen, P. L. & De Boni, U. Rearrangement of centromeric satellite DNA in hippocampal neurons exhibiting long-term potentiation. Brain Res. Mol. Brain Res. 14, 101-108 (1992).
    • (1992) Brain Res. Mol. Brain Res , vol.14 , pp. 101-108
    • Billia, F.1    Baskys, A.2    Carlen, P.L.3    De Boni, U.4
  • 65
    • 22344441631 scopus 로고    scopus 로고
    • Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation
    • Brero, A. et al. Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation. J. Cell Biol. 169, 733-743 (2005).
    • (2005) J. Cell Biol , vol.169 , pp. 733-743
    • Brero, A.1
  • 66
    • 0025649160 scopus 로고
    • A view of interphase chromosomes
    • Manuelidis, L. A view of interphase chromosomes. Science 250, 1533-1540 (1990).
    • (1990) Science , vol.250 , pp. 1533-1540
    • Manuelidis, L.1
  • 67
    • 3242748982 scopus 로고    scopus 로고
    • Postnatal changes of pericentromeric heterochromatin and nucleoli in postmitotic Purkinje cells during murine cerebellum development
    • Solovei, I., Grandi, N., Knoth, R., Folk, B. & Cremer, T. Postnatal changes of pericentromeric heterochromatin and nucleoli in postmitotic Purkinje cells during murine cerebellum development. Cytogenet. Genome Res. 105, 302-310 (2004).
    • (2004) Cytogenet. Genome Res , vol.105 , pp. 302-310
    • Solovei, I.1    Grandi, N.2    Knoth, R.3    Folk, B.4    Cremer, T.5
  • 68
    • 33646519677 scopus 로고    scopus 로고
    • Cellular memory and dynamic regulation of Polycomb group proteins
    • Bantignies, F. & Cavalli, G. Cellular memory and dynamic regulation of Polycomb group proteins. Curr. Opin. Cell Biol. 18, 275-283 (2006).
    • (2006) Curr. Opin. Cell Biol , vol.18 , pp. 275-283
    • Bantignies, F.1    Cavalli, G.2
  • 70
    • 0141706718 scopus 로고    scopus 로고
    • Bantignies, F., Grimaud, C., Lavrov, S., Gabut, M. & Cavalli, G. Inheritance of Polycomb-dependent chromosomal interactions in Drosophila. Genes Dev. 17, 2406-2420 (2003). This work describes long-distance pairing of genomic regions that contain Polycomb response elements in D. melanogaster nuclei. These interactions enhance transcriptional repression that is mediated by Polycomb group proteins.
    • Bantignies, F., Grimaud, C., Lavrov, S., Gabut, M. & Cavalli, G. Inheritance of Polycomb-dependent chromosomal interactions in Drosophila. Genes Dev. 17, 2406-2420 (2003). This work describes long-distance pairing of genomic regions that contain Polycomb response elements in D. melanogaster nuclei. These interactions enhance transcriptional repression that is mediated by Polycomb group proteins.
  • 71
    • 0032550226 scopus 로고    scopus 로고
    • The distribution of Polycomb-group proteins during cell division and development in Drosophila embryos: Impact on models for silencing
    • Buchenau, P., Hodgson, J., Strutt, H. & Arndt-Jovin, D. J. The distribution of Polycomb-group proteins during cell division and development in Drosophila embryos: impact on models for silencing. J. Cell Biol. 141, 469-481 (1998).
    • (1998) J. Cell Biol , vol.141 , pp. 469-481
    • Buchenau, P.1    Hodgson, J.2    Strutt, H.3    Arndt-Jovin, D.J.4
  • 72
    • 0032563598 scopus 로고    scopus 로고
    • The human polycomb group complex associates with pericentromeric heterochromatin to form a novel nuclear domain
    • Saurin, A. J. et al. The human polycomb group complex associates with pericentromeric heterochromatin to form a novel nuclear domain. J. Cell Biol. 142, 887-898 (1998).
    • (1998) J. Cell Biol , vol.142 , pp. 887-898
    • Saurin, A.J.1
  • 73
    • 33745599723 scopus 로고    scopus 로고
    • Vazquez, J., Muller, M., Pirrotta, V. & Sedat, J. W. The Mcp element mediates stable long-range chromosome-chromosome interactions in Drosophila. Mol. Biol. Cell 17, 2158-2165 (2006).
    • Vazquez, J., Muller, M., Pirrotta, V. & Sedat, J. W. The Mcp element mediates stable long-range chromosome-chromosome interactions in Drosophila. Mol. Biol. Cell 17, 2158-2165 (2006).
  • 74
    • 33644751726 scopus 로고    scopus 로고
    • Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation
    • Bacher, C. P. et al. Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation. Nature Cell Biol. 8, 293-299 (2006).
    • (2006) Nature Cell Biol , vol.8 , pp. 293-299
    • Bacher, C.P.1
  • 75
    • 33644557773 scopus 로고    scopus 로고
    • Transient homologous chromosome pairing marks the onset of X inactivation
    • Xu, N., Tsai, C. L. & Lee, J. T. Transient homologous chromosome pairing marks the onset of X inactivation. Science 311, 1149-1152 (2006).
    • (2006) Science , vol.311 , pp. 1149-1152
    • Xu, N.1    Tsai, C.L.2    Lee, J.T.3
  • 76
    • 0036923833 scopus 로고    scopus 로고
    • Looping and interaction between hypersensitive sites in the active β-globin locus
    • Tolhuis, B., Palstra, R. J., Splinter, E., Grosveld, F. & de Laat, W. Looping and interaction between hypersensitive sites in the active β-globin locus. Mol. Cell 10, 1453-1465 (2002).
    • (2002) Mol. Cell , vol.10 , pp. 1453-1465
    • Tolhuis, B.1    Palstra, R.J.2    Splinter, E.3    Grosveld, F.4    de Laat, W.5
  • 77
    • 33746228114 scopus 로고    scopus 로고
    • Interchromosomal interactions and olfactory receptor choice
    • Lomvardas, S. et al. Interchromosomal interactions and olfactory receptor choice. Cell 126, 403-413 (2006).
    • (2006) Cell , vol.126 , pp. 403-413
    • Lomvardas, S.1
  • 78
    • 5444243359 scopus 로고    scopus 로고
    • Active genes dynamically colocalize to shared sites of ongoing transcription
    • Osborne, C. S. et al. Active genes dynamically colocalize to shared sites of ongoing transcription. Nature Genet. 36, 1065-1071 (2004).
    • (2004) Nature Genet , vol.36 , pp. 1065-1071
    • Osborne, C.S.1
  • 79
    • 0037083376 scopus 로고    scopus 로고
    • Capturing chromosome conformation
    • Dekker, J., Rippe, K., Dekker, M. & Kleckner, N. Capturing chromosome conformation. Science 295, 1306-1311 (2002).
    • (2002) Science , vol.295 , pp. 1306-1311
    • Dekker, J.1    Rippe, K.2    Dekker, M.3    Kleckner, N.4
  • 80
    • 31344477982 scopus 로고    scopus 로고
    • The three 'C' s of chromosome conformation capture: Controls, controls, controls
    • Dekker, J. The three 'C' s of chromosome conformation capture: controls, controls, controls. Nature Methods 3, 17-21 (2006).
    • (2006) Nature Methods , vol.3 , pp. 17-21
    • Dekker, J.1
  • 81
    • 20444494936 scopus 로고    scopus 로고
    • Spilianakis, C. G., Lalioti, M. D., Town, T., Lee, G. R. & Flavell, R. A. Interchromosomal associations between alternatively expressed loci. Nature 435, 637-645 (2005). This work describes the co-localization of transcriptionally poised genes in naive T lymphocytes. The genes are located on different chromosomes, indicating the existence of spatial networks of gene regulation.
    • Spilianakis, C. G., Lalioti, M. D., Town, T., Lee, G. R. & Flavell, R. A. Interchromosomal associations between alternatively expressed loci. Nature 435, 637-645 (2005). This work describes the co-localization of transcriptionally poised genes in naive T lymphocytes. The genes are located on different chromosomes, indicating the existence of spatial networks of gene regulation.
  • 82
    • 33745743206 scopus 로고    scopus 로고
    • Genome-wide scanning of HoxB1-associated loci in mouse ES cells using an open-ended chromosome conformation capture methodology
    • Wurtele, H. & Chartrand, P. Genome-wide scanning of HoxB1-associated loci in mouse ES cells using an open-ended chromosome conformation capture methodology. Chromosome Res. 14, 477-495 (2006).
    • (2006) Chromosome Res , vol.14 , pp. 477-495
    • Wurtele, H.1    Chartrand, P.2
  • 83
    • 2442695407 scopus 로고    scopus 로고
    • Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription
    • Chambeyron, S. & Bickmore, W. A. Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription. Genes Dev. 18, 1119-1130 (2004).
    • (2004) Genes Dev , vol.18 , pp. 1119-1130
    • Chambeyron, S.1    Bickmore, W.A.2
  • 84
    • 33750212321 scopus 로고    scopus 로고
    • Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C)
    • Simonis, M. et al. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). Nature Genet. (2006).
    • (2006) Nature Genet
    • Simonis, M.1
  • 85
    • 33745593972 scopus 로고    scopus 로고
    • Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence
    • Shopland, L. S. et al. Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence. J. Cell Biol. 174, 27-38 (2006).
    • (2006) J. Cell Biol , vol.174 , pp. 27-38
    • Shopland, L.S.1
  • 86
    • 3543018516 scopus 로고    scopus 로고
    • Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops
    • Murrell, A., Heeson, S. & Reik, W. Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nature Genet. 36, 889-893 (2004).
    • (2004) Nature Genet , vol.36 , pp. 889-893
    • Murrell, A.1    Heeson, S.2    Reik, W.3
  • 87
    • 33746063711 scopus 로고    scopus 로고
    • CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2
    • Kurukuti, S. et al. CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc. Natl Acad. Sci. USA 103, 10684-10689 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 10684-10689
    • Kurukuti, S.1
  • 88
    • 33645814398 scopus 로고    scopus 로고
    • CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1
    • Ling, J. Q. et al. CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1. Science 312, 269-272 (2006).
    • (2006) Science , vol.312 , pp. 269-272
    • Ling, J.Q.1
  • 89
    • 33750203582 scopus 로고    scopus 로고
    • Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions
    • Zhao, Z. et al. Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions. Nature Genet. (2006).
    • (2006) Nature Genet
    • Zhao, Z.1
  • 90
    • 0041346000 scopus 로고    scopus 로고
    • An uncertainty principle in chromosome positioning
    • Parada, L. A., Roix, J. J. & Misteli, T. An uncertainty principle in chromosome positioning. Trends Cell Biol. 13, 393-396 (2003).
    • (2003) Trends Cell Biol , vol.13 , pp. 393-396
    • Parada, L.A.1    Roix, J.J.2    Misteli, T.3
  • 91
    • 30944469000 scopus 로고    scopus 로고
    • Brown, J. M. et al. Coregulated human globin genes are frequently in spatial proximity when active. J. Cell Biol. 172, 177-187 (2006). This study reports that, unlike what is observed in human cells, active globin genes do not co-localize in expressing mouse intermediate erythroblasts. This finding highlights the importance of species-specific chromosomal context in determining the frequency of gene kissing.
    • Brown, J. M. et al. Coregulated human globin genes are frequently in spatial proximity when active. J. Cell Biol. 172, 177-187 (2006). This study reports that, unlike what is observed in human cells, active globin genes do not co-localize in expressing mouse intermediate erythroblasts. This finding highlights the importance of species-specific chromosomal context in determining the frequency of gene kissing.
  • 92
    • 18744375181 scopus 로고    scopus 로고
    • Concepts in nuclear architecture
    • Misteli, T. Concepts in nuclear architecture. BioEssays 27, 477-487 (2005).
    • (2005) BioEssays , vol.27 , pp. 477-487
    • Misteli, T.1
  • 93
    • 33644770293 scopus 로고    scopus 로고
    • Grimaud, C. et al. RNAi components are required for nuclear clustering of Polycomb group response elements. Cell 124, 957-971 (2006). This work reports that components of the RNAi machinery are involved in the co-localization of Fab7-containing chromosomal regions at Polycomb bodies in D. melanogaster nuclei.
    • Grimaud, C. et al. RNAi components are required for nuclear clustering of Polycomb group response elements. Cell 124, 957-971 (2006). This work reports that components of the RNAi machinery are involved in the co-localization of Fab7-containing chromosomal regions at Polycomb bodies in D. melanogaster nuclei.
  • 94
    • 10944252995 scopus 로고    scopus 로고
    • The function of nuclear architecture: A genetic approach
    • Taddei, A., Hediger, F., Neumann, F. R. & Gasser, S. M. The function of nuclear architecture: a genetic approach. Annu. Rev. Genet. 38, 305-345 (2004).
    • (2004) Annu. Rev. Genet , vol.38 , pp. 305-345
    • Taddei, A.1    Hediger, F.2    Neumann, F.R.3    Gasser, S.M.4
  • 95
    • 12344291073 scopus 로고    scopus 로고
    • Dark matter in the genome: Evidence of widespread transcription detected by microarray tiling experiments
    • Johnson, J. M., Edwards, S., Shoemaker, D. & Schadt, E. E. Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments. Trends Genet. 21, 93-102 (2005).
    • (2005) Trends Genet , vol.21 , pp. 93-102
    • Johnson, J.M.1    Edwards, S.2    Shoemaker, D.3    Schadt, E.E.4
  • 96
    • 0037012881 scopus 로고    scopus 로고
    • Large-scale transcriptional activity in chromosomes 21 and 22
    • Kapranov, P. et al. Large-scale transcriptional activity in chromosomes 21 and 22. Science 296, 916-919 (2002).
    • (2002) Science , vol.296 , pp. 916-919
    • Kapranov, P.1
  • 98
    • 0041886706 scopus 로고    scopus 로고
    • Micromechanics of chromatin and chromosomes
    • Marko, J. F. & Poirier, M. G. Micromechanics of chromatin and chromosomes. Biochem. Cell Biol. 81, 209-220 (2003).
    • (2003) Biochem. Cell Biol , vol.81 , pp. 209-220
    • Marko, J.F.1    Poirier, M.G.2
  • 99
    • 7544242666 scopus 로고    scopus 로고
    • The dynamic response of upstream DNA to transcription-generated torsional stress
    • Kouzine, F., Liu, J., Sanford, S., Chung, H. J. & Levens, D. The dynamic response of upstream DNA to transcription-generated torsional stress. Nature Struct. Mol. Biol. 11, 1092-1100 (2004).
    • (2004) Nature Struct. Mol. Biol , vol.11 , pp. 1092-1100
    • Kouzine, F.1    Liu, J.2    Sanford, S.3    Chung, H.J.4    Levens, D.5
  • 100
    • 0035110880 scopus 로고    scopus 로고
    • Experimental observations of a nuclear matrix
    • Nickerson, J. Experimental observations of a nuclear matrix. J. Cell Sci. 114, 463-474 (2001).
    • (2001) J. Cell Sci , vol.114 , pp. 463-474
    • Nickerson, J.1
  • 101
    • 0033538846 scopus 로고    scopus 로고
    • Association of chromosome territories with the nuclear matrix. Disruption of human chromosome territories correlates with the release of a subset of nuclear matrix proteins
    • Ma, H., Siegel, A. J. & Berezney, R. Association of chromosome territories with the nuclear matrix. Disruption of human chromosome territories correlates with the release of a subset of nuclear matrix proteins. J. Cell Biol. 146, 531-542 (1999).
    • (1999) J. Cell Biol , vol.146 , pp. 531-542
    • Ma, H.1    Siegel, A.J.2    Berezney, R.3
  • 102
    • 18844412748 scopus 로고    scopus 로고
    • Developmentally induced changes in transcriptional program alter spatial organization across chromosomes
    • Casolari, J. M., Brown, C. R., Drubin, D. A., Rando, O. J. & Silver, P. A. Developmentally induced changes in transcriptional program alter spatial organization across chromosomes. Genes Dev. 19, 1188-1198 (2005).
    • (2005) Genes Dev , vol.19 , pp. 1188-1198
    • Casolari, J.M.1    Brown, C.R.2    Drubin, D.A.3    Rando, O.J.4    Silver, P.A.5


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