Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos

Cell

Volumn 156, Issue 4, 2014, Pages 836-843

  Niu, Yuyu ^a,e   Shen, Bin ^b   Cui, Yiqiang ^c   Chen, Yongchang ^a,e   Wang, Jianying ^b   Wang, Lei ^c   Kang, Yu ^a,e   Zhao, Xiaoyang ^d   Si, Wei ^a,e   Li, Wei ^d   Xiang, Andy Peng ^f   Zhou, Jiankui ^b   Guo, Xuejiang ^c   Bi, Ye ^c   Si, Chenyang ^a,e   Hu, Bian ^b   Dong, Guoying ^c   Wang, Hong ^a,e   Zhou, Zuomin ^c   Li, Tianqing ^a,e   Tan, Tao ^a,e   Pu, Xiuqiong ^a,e   Wang, Fang ^a,e   Ji, Shaohui ^a,e   Zhou, Qi ^d   Huang, Xingxu ^b   Ji, Weizhi ^a,e   Sha, Jiahao ^c   more..

^a Yunnan Key Laboratory of Primate Biomedical Research   (China)

^b NANJING UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

^d INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^e National Engineering Research Center of Biomedicine and Animal Science   (China)

^f SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CAS9 NUCLEASE; MESSENGER RNA; NUCLEAR RECEPTOR DAX 1; NUCLEASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RAG1 PROTEIN; RNA POLYMERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CODON; CONTROLLED STUDY; CRISPR CAS SYSTEM; DNA MODIFICATION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; FEMALE; GENE TARGETING; GENETIC ENGINEERING; GENOME; IN VITRO STUDY; MACACA FASCICULARIS; MOSAICISM; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRISPR CAS9 SYSTEM; ELECTROPORATION; EMBRYO CELL; GENE DISRUPTION; GENE EXPRESSION; INTRACYTOPLASMIC SPERM INJECTION; MICROINJECTION;

ANIMALIA; MACACA FASCICULARIS;

ANIMALS; BASE SEQUENCE; CELL LINE; EMBRYO, MAMMALIAN; FEMALE; GENE TARGETING; HUMANS; MACACA FASCICULARIS; MOLECULAR SEQUENCE DATA; MOSAICISM; SEQUENCE ALIGNMENT;

EID: 84894081986     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.01.027     Document Type: Article

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