Highly efficient Cas9-mediated transcriptional programming

Nature Methods

Volumn 12, Issue 4, 2015, Pages 326-328

  Chavez, Alejandro ^a,b,c   Scheiman, Jonathan ^a,c   Vora, Suhani ^a,c,d   Pruitt, Benjamin W ^a   Tuttle, Marcelle ^a   P R Iyer, Eswar ^a,c   Lin, Shuailiang ^c,e   Kiani, Samira ^d   Guzman, Christopher D ^a   Wiegand, Daniel J ^a   Ter Ovanesyan, Dmitry ^a,c   Braff, Jonathan L ^a   Davidsohn, Noah ^a,c   Housden, Benjamin E ^c   Perrimon, Norbert ^c   Weiss, Ron ^d,f   Aach, John ^c   Collins, James J ^a,d,g   Church, George M ^a,c  

^a HARVARD UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d USA   (United States)

^e TSINGHUA UNIVERSITY   (China)

^f Department of Electrical Engineering and Computer Science   (United States)

^g BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; GUIDE RNA; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 2; TRANSCRIPTION FACTOR MASH1; ENDONUCLEASE;

ARTICLE; CELL MATURATION; EMBRYO; GENE ACTIVATION; GENE EXPRESSION; GENE INDUCTION; GENE LOCUS; GENE THERAPY; GENETIC SCREENING; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; NERVE CELL DIFFERENTIATION; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TRANSCRIPTION INITIATION; CELL DIFFERENTIATION; CYTOLOGY; GENETIC PROCEDURES; GENETICS; HEK293 CELL LINE; INDUCED PLURIPOTENT STEM CELL; NERVE CELL; STAPHYLOCOCCUS AUREUS;

CELL DIFFERENTIATION; ENDONUCLEASES; GENETIC TECHNIQUES; HEK293 CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; NEURONS; RNA, GUIDE; STAPHYLOCOCCUS AUREUS; TRANSCRIPTIONAL ACTIVATION;

EID: 84926521955     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.3312     Document Type: Article

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