CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

Protein and Cell

Volumn 6, Issue 5, 2015, Pages 363-372

  Liang, Puping ^a   Xu, Yanwen ^a   Zhang, Xiya ^a   Ding, Chenhui ^a   Huang, Rui ^a   Zhang, Zhen ^a   Lv, Jie ^a   Xie, Xiaowei ^a   Chen, Yuxi ^a   Li, Yujing ^a   Sun, Ying ^a   Bai, Yaofu ^a   Songyang, Zhou ^a   Ma, Wenbin ^a   Zhou, Canquan ^a   Huang, Junjiu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

CRISPR Cas9; gene editing; homologous recombination; human tripronuclear zygotes; whole exome sequencing; thalassemia

Indexed keywords

HEMOGLOBIN VARIANT;

BLASTOCYST; CRISPR CAS SYSTEM; GENETICS; HUMAN; METABOLISM; ZYGOTE;

BLASTOCYST; CRISPR-CAS SYSTEMS; HEMOGLOBINS, ABNORMAL; HUMANS; ZYGOTE;

EID: 84930618439     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-015-0153-5     Document Type: Article

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