Erratum: In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system (Nature (2014) 516 (423-427) DOI: 10.1038/nature13902);In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system

Nature

Volumn 516, Issue 7531, 2014, Pages 423-428

  Maddalo, Danilo ^a   Manchado, Eusebio ^a   Concepcion, Carla P ^a,b   Bonetti, Ciro ^a   Vidigal, Joana A ^a   Han, Yoon Chi ^a   Ogrodowski, Paul ^a   Crippa, Alessandra ^c   Rekhtman, Natasha ^a   Stanchina, Elisa De ^a   Lowe, Scott W ^a,d   Ventura, Andrea ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c SAN GERARDO HOSPITAL   (Italy)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; CASPASE 9; MICROTUBULE ASSOCIATED PROTEIN 4; ANTINEOPLASTIC AGENT; CRIZOTINIB; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

CANCER; CHROMOSOME; CYTOLOGY; ECHINODERM; ENZYME ACTIVITY; HISTOPATHOLOGY; PROTEIN; RODENT;

3T3 CELL LINE; ARTICLE; CHROMOSOME 17; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DNA STRAND BREAKAGE; DOUBLE STRANDED DNA BREAK; EUKARYOTIC CELL; FUSION GENE; GENETIC ENGINEERING; HUMAN; IN VIVO STUDY; INTRON; LOSS OF FUNCTION MUTATION; LUNG CANCER; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOMATIC CELL; ANIMAL; CELL CULTURE; CHROMOSOME INVERSION; DISEASE MODEL; ENZYMOLOGY; GENE TRANSLOCATION; GENETICS; LUNG NEOPLASMS; METABOLISM; MOUSE; PATHOLOGY; PROCEDURES;

ANIMALIA; ECHINODERMATA; MUS;

ANIMALS; ANTINEOPLASTIC AGENTS; CASPASE 9; CELLS, CULTURED; CHROMOSOME INVERSION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; DISEASE MODELS, ANIMAL; GENETIC ENGINEERING; LUNG NEOPLASMS; MICE; NIH 3T3 CELLS; PROTEIN KINASE INHIBITORS; PYRAZOLES; PYRIDINES; RECEPTOR PROTEIN-TYROSINE KINASES; TRANSLOCATION, GENETIC;

EID: 84922735816     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14571     Document Type: Erratum

References (30)

1. Taki, T. & Taniwaki, M. Chromosomal translocations in cancer and their relevance for therapy. Curr. Opin. Oncol. 18, 62-68 (2006).
2. Soda, M. et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 448, 561-566 (2007).
3. Kwak, E. L. et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N. Engl. J. Med. 363, 1693-1703 (2010).
4. Tuveson, D. A. &; Jacks, T. Technologically advanced cancermodeling in mice. Curr. Opin. Genet. Dev. 12, 105-110 (2002).
5. Sharpless, N. E. & Depinho, R. A. Themightymouse: genetically engineeredmouse models in cancer drug development. Nature Rev. Drug Discov. 5, 741-754 (2006).
6. Pirazzoli, V. et al. Acquired resistance of EGFR-mutant lung adenocarcinomas to afatinib plus cetuximab is associated with activation of mTORC1. Cell Rep. 7, 999-1008 (2014).
7. Bergers, G. & Hanahan, D. Modes of resistance to anti-angiogenic therapy. Nature Rev. Cancer 8, 592-603 (2008).
8. Rottenberg, S. et al. Selective induction of chemotherapy resistance of mammary tumors in a conditionalmousemodel for hereditary breast cancer. Proc. Natl Acad. Sci. USA 104, 12117-12122 (2007).
9. Heisterkamp, N. et al. Acute leukaemia in bcr/abl transgenic mice. Nature 344, 251-253 (1990).
10. Zuber, J. et al. Mouse models of human AML accurately predict chemotherapy response. Genes Dev. 23, 877-889 (2009).
11. Lange, K. et al. Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice. Oncogene 22, 517-527 (2003).
12. Chiarle, R. et al. NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors. Blood 101, 1919-1927 (2003).
13. Soda, M. et al. A mouse model for EML4-ALK-positive lung cancer. Proc. Natl Acad. Sci. USA 105, 19893-19897 (2008).
14. Corral, J. et al.AnMll-AF9fusiongenemade byhomologous recombinationcauses acute leukemia in chimeric mice: a method to create fusion oncogenes. Cell 85, 853-861 (1996).
15. Smith, A. J. et al. A site-directed chromosomal translocation induced inembryonic stem cells by Cre-loxP recombination. Nature Genet. 9, 376-385 (1995).
16. Collins, E. C., Pannell, R., Simpson, E. M., Forster, A. & Rabbitts, T. H. Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development. EMBO Rep. 1, 127-132 (2000).
17. Piganeau, M. et al.Cancer translocations in human cells induced by zinc finger and TALE nucleases. Genome Res. 23, 1182-1193 (2013).
18. Torres, R. et al. Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system. Nature Commun. 5, 3964 (2014).
19. Brunet, E. et al. Chromosomal translocations induced at specified loci in human stem cells. Proc. Natl Acad. Sci. USA 106, 10620-10625 (2009).
20. Choi, P. S. & Meyerson, M. Targeted genomic rearrangements using CRISPR/Cas technology. Nature Commun. 5, 3728 (2014).
21. Choi, Y. L. et al. Identification of novel isoforms of theEML4-ALK transforming gene in non-small cell lung cancer. Cancer Res. 68, 4971-4976 (2008).
22. Horvath, P. & Barrangou, R. CRISPR/Cas, the immune system of bacteria and archaea. Science 327, 167-170 (2010).
23. Jinek, M. et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816-821 (2012).
24. Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819-823 (2013).
25. Morris, S. W. et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene,NPM, in non-Hodgkin's lymphoma. Science 263, 1281-1284 (1994).
26. DuPage, M., Dooley, A. L. & Jacks, T. Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nature Protocols 4, 1064-1072 (2009).
27. Nishino, M. et al. Histologic and cytomorphologic features of ALK-rearranged lung adenocarcinomas. Modern Pathol. 25, 1462-1472 (2012).
28. Jackson, E. L. et al. Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev. 15, 3243-3248 (2001).
29. Chiarle, R., Voena, C., Ambrogio, C., Piva, R. & Inghirami, G. The anaplastic lymphoma kinase in the pathogenesis of cancer. Nature Rev. Cancer 8, 11-23 (2008).
30. Canver, M. C. et al. Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells. J. Biol. Chem. 289, 21312-21324 (2014).