-
1
-
-
35648984988
-
The mitochondrion as Janus Bifrons
-
DOI 10.1134/S0006297907100094
-
D.B. Zorov, N.K. Isave, E.Y. Plotnikov, L.D. Zorova, E.V. Stelmashook, and A.K. Vasileva The mitochondrion as Janus Bifrons Biochemistry (Mosc) 72 2007 1115 1126 (Pubitemid 350022593)
-
(2007)
Biochemistry (Moscow)
, vol.72
, Issue.10
, pp. 1115-1126
-
-
Zorov, D.B.1
Isaev, N.K.2
Plotnikov, E.Yu.3
Zorova, L.D.4
Stelmashook, E.V.5
Vasileva, A.K.6
Arkhangelskaya, A.A.7
Khrjapenkova, T.G.8
-
2
-
-
0034796353
-
Role of free radicals in the neurodegenerative diseases
-
B. Halliwell Role of free radicals in the neurodegenerative diseases Drugs Aging 18 2001 685 716
-
(2001)
Drugs Aging
, vol.18
, pp. 685-716
-
-
Halliwell, B.1
-
3
-
-
0036830474
-
Mitochondrial function and dysfunction in the cell: Its relevance to aging and aging-related disease
-
DOI 10.1016/S1357-2725(02)00077-8, PII S1357272502000778
-
D.G. Nicholls Mitochondrial function and dysfunction in the cell: its relevance to aging and aging-related disease Int J Biochem Cell Biol 34 2002 1372 1381 (Pubitemid 35245396)
-
(2002)
International Journal of Biochemistry and Cell Biology
, vol.34
, Issue.11
, pp. 1372-1381
-
-
Nicholls, D.G.1
-
4
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
-
DOI 10.1146/annurev.genet.39.110304.095751
-
D.C. Wallace A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn of evolutionary medicine Annu Rev Genet 39 2002 359 407 (Pubitemid 43011120)
-
(2005)
Annual Review of Genetics
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
5
-
-
0029053451
-
Superoxide radical and superoxide dismutases
-
I. Fridovich Superoxide radical and superoxide dismutases Annu Rev Biochem 64 1995 97 112
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 97-112
-
-
Fridovich, I.1
-
6
-
-
0141992104
-
From molecules to mammals: What's NOS got to do with it?
-
DOI 10.1046/j.1365-201X.2003.01182.x
-
I.N. Mungrue, D.S. Bredt, D.J. Stewart, and M. Husain From molecules to mammals: what's NOS got to do with it? Acta Physiol Scand 179 2003 123 135 (Pubitemid 37249246)
-
(2003)
Acta Physiologica Scandinavica
, vol.179
, Issue.2
, pp. 123-135
-
-
Mungrue, I.N.1
Bredt, D.S.2
Stewart, D.J.3
Husain, M.4
-
7
-
-
77956216847
-
Mitochondrial and cell death mechanisms in neurodegenerative disease
-
L.J. Martin Mitochondrial and cell death mechanisms in neurodegenerative disease Pharmaceuticals 3 2010 839 915
-
(2010)
Pharmaceuticals
, vol.3
, pp. 839-915
-
-
Martin, L.J.1
-
8
-
-
0036369531
-
OPA1 (Kjer type) dominant optic atrophy: A novel mitochondrial disease
-
DOI 10.1006/mgme.2001.3278
-
C. Delettre, G. Lenaers, L. Pelloquin, P. Belenguer, and C.P. Hamel OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease Mol Genet Metab 75 2002 97 107 (Pubitemid 34975762)
-
(2002)
Molecular Genetics and Metabolism
, vol.75
, Issue.2
, pp. 97-107
-
-
Delettre, C.1
Lenaers, G.2
Pelloquin, L.3
Belenguer, P.4
Hamel, C.P.5
-
9
-
-
27744491193
-
Emerging functions of mammalian mitochondrial fusion and fission
-
H. Chen, and D.C. Chan Emerging functions of mammalian mitochondrial fusion and fission Hum Mol Genet 14 2005 R283 R289
-
(2005)
Hum Mol Genet
, vol.14
-
-
Chen, H.1
Chan, D.C.2
-
10
-
-
0026702249
-
Leber's hereditary optic neuropathy: A model for mitochondrial neurodegenerative diseases
-
M.D. Brown, A.S. Voljavec, M.T. Lott, I. MacDolald, and D.C. Wallace Leber's hereditary optic neuropathy: a model for mitochondrial neurodegenerative diseases FASEB J 6 1992 2791 2799
-
(1992)
FASEB J
, vol.6
, pp. 2791-2799
-
-
Brown, M.D.1
Voljavec, A.S.2
Lott, M.T.3
MacDolald, I.4
Wallace, D.C.5
-
11
-
-
57849140614
-
Molecular and clinical genetics of mitochondrial disease due to POLG mutations
-
L.-J.C. Wong, R.K. Naviaux, N. Brunetti-Pierri, Q. Zhang, E.S. Schmitt, and C. Truong Molecular and clinical genetics of mitochondrial disease due to POLG mutations Hum Mutat 29 2008 E150 E172
-
(2008)
Hum Mutat
, vol.29
-
-
Wong, L.-J.C.1
Naviaux, R.K.2
Brunetti-Pierri, N.3
Zhang, Q.4
Schmitt, E.S.5
Truong, C.6
-
12
-
-
58149163606
-
Twinkle mutations associated with autosomal dominant progressive external opthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling
-
S. Goffart, H.M. Cooper, H. Tyynismaa, S. Wanrooij, A. Suomalainen, and J.N. Spelbrink Twinkle mutations associated with autosomal dominant progressive external opthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling Hum Mol Genet 18 2009 328 340
-
(2009)
Hum Mol Genet
, vol.18
, pp. 328-340
-
-
Goffart, S.1
Cooper, H.M.2
Tyynismaa, H.3
Wanrooij, S.4
Suomalainen, A.5
Spelbrink, J.N.6
-
13
-
-
0036225534
-
A novel D104G mutation in the adenine nucleotide translocator 1 gene in autosomal dominant external opthalmoplegia patients with mitochondrial DNA with multiple deletions
-
H. Komaki, T. Fukazawa, H. Houzen, K. Yoshida, I. Nonaka, and Y. Goto A novel D104G mutation in the adenine nucleotide translocator 1 gene in autosomal dominant external opthalmoplegia patients with mitochondrial DNA with multiple deletions Ann Neurol 51 2002 645 648
-
(2002)
Ann Neurol
, vol.51
, pp. 645-648
-
-
Komaki, H.1
Fukazawa, T.2
Houzen, H.3
Yoshida, K.4
Nonaka, I.5
Goto, Y.6
-
14
-
-
0032125488
-
Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis
-
DOI 10.1016/S0361-9230(98)00024-0, PII S0361923098000240
-
L.J. Martin, N.A. Al-Abdulla, A.M. Brambrink, J.R. Kirsch, F.E. Sieber, and C. Portera-Cailliau Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contributions of apoptosis and necrosis Brain Res Bull 46 1998 281 309 (Pubitemid 28294822)
-
(1998)
Brain Research Bulletin
, vol.46
, Issue.4
, pp. 281-309
-
-
Martin, L.J.1
Al-Abdulla, N.A.2
Brambrink, A.M.3
Kiesch, J.R.4
Sieber, F.E.5
Portera-Cailliau, C.6
-
15
-
-
27844480078
-
Apoptosis in perinatal hypoxic-ischemic brain injury: How important is it and should it be inhibited?
-
DOI 10.1016/j.brainresrev.2005.07.003, PII S0165017305001128
-
F.J. Northington, E.M. Graham, and L.J. Martin Apoptosis in perinatal hypoxic-ischemic brain injury: how important is it and should it be inhibited? Brain Res Rev 50 2005 244 257 (Pubitemid 41654395)
-
(2005)
Brain Research Reviews
, vol.50
, Issue.2
, pp. 244-257
-
-
Northington, F.J.1
Graham, E.M.2
Martin, L.J.3
-
16
-
-
71849092300
-
The mitochondrial permeability transition pore: A molecular target for amyotrophic lateral sclerosis
-
L.J. Martin The mitochondrial permeability transition pore: a molecular target for amyotrophic lateral sclerosis Biochim Biophys Acta 1802 2010 186 197
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 186-197
-
-
Martin, L.J.1
-
17
-
-
0041309469
-
Cyclophilin D as a drug target
-
DOI 10.2174/0929867033457160
-
P.C. Waldmeier, K. Zimmermann, T. Qian, M. Tintelnot-Blomley, and J.J. Lemasters Cyclophilin D as a drug target Curr Med Chem 10 2003 1485 1506 (Pubitemid 36896552)
-
(2003)
Current Medicinal Chemistry
, vol.10
, Issue.16
, pp. 1485-1506
-
-
Waldmeier, P.C.1
Zimmermann, K.2
Qian, T.3
Tintelnot-Blomley, M.4
Lemasters, J.J.5
-
18
-
-
4544280654
-
Mitochondria and aging: A role for the permeability transition?
-
DOI 10.1046/j.1474-9728.2003.00073.x
-
M. Crompton Mitochondria and aging: a role for the permeability transition? Aging Cell 3 2004 3 6 (Pubitemid 40246654)
-
(2004)
Aging Cell
, vol.3
, Issue.1
, pp. 3-6
-
-
Crompton, M.1
-
19
-
-
67349117275
-
What is the mitochondrial permeability transition pore?
-
A.P. Halestrap What is the mitochondrial permeability transition pore? J Mol Cell Cardiol 46 2009 821 831
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 821-831
-
-
Halestrap, A.P.1
-
20
-
-
33646255246
-
The mitochondrial permeability transition from in vitro artifact to disease target
-
P. Bernardi, A. Krauskopf, E. Basso, V. Petronilli, E. Blalchy-Dyson, and F. Di Lisa The mitochondrial permeability transition from in vitro artifact to disease target FEBS J 273 2006 2077 2099
-
(2006)
FEBS J
, vol.273
, pp. 2077-2099
-
-
Bernardi, P.1
Krauskopf, A.2
Basso, E.3
Petronilli, V.4
Blalchy-Dyson, E.5
Di Lisa, F.6
-
21
-
-
28744449206
-
Mitochondrial Aβ: A potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
-
DOI 10.1096/fj.05-3735fje
-
C. Caspersen, N. Wang, J. Yao, A. Sosunov, X. Chen, and J.W. Lustbader Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease FASEB J 19 2005 2040 2041 (Pubitemid 41759758)
-
(2005)
FASEB Journal
, vol.19
, Issue.14
, pp. 2040-2041
-
-
Caspersen, C.1
Wang, N.2
Yao, J.3
Sosunov, A.4
Chen, X.5
Lustbader, J.W.6
Xu, H.W.7
Stern, D.8
McKhann, G.9
Yan, S.D.10
-
22
-
-
0027293275
-
ALS, SOD and peroxynitrite
-
J.S. Beckman, M. Carson, C.D. Smith, and W.H. Koppenol ALS, SOD and peroxynitrite Nature 364 1993 548
-
(1993)
Nature
, vol.364
, pp. 548
-
-
Beckman, J.S.1
Carson, M.2
Smith, C.D.3
Koppenol, W.H.4
-
23
-
-
0036807332
-
DNA damage profiling in motor neurons: A single-cell analysis by comet assay
-
L.J. Martin, and Z. Liu DNA damage profiling in motor neurons: a single-cell analysis by comet assay Neurochem Res 27 2002 1089 1100
-
(2002)
Neurochem Res
, vol.27
, pp. 1089-1100
-
-
Martin, L.J.1
Liu, Z.2
-
24
-
-
0037441389
-
Characterization and function of mitochondrial nitric-oxide synthase
-
C. Giulini Characterization and function of mitochondrial nitric-oxide synthase Free Radic Biol Med 34 2003 397 408
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 397-408
-
-
Giulini, C.1
-
25
-
-
0033286476
-
Nitric oxide, cytochrome c, and mitochondria
-
G.C. Brown, and V. Borutaite Nitric oxide, cytochrome c, and mitochondria Biochem Soc Symp 66 1999 17 25
-
(1999)
Biochem Soc Symp
, vol.66
, pp. 17-25
-
-
Brown, G.C.1
Borutaite, V.2
-
26
-
-
13944261588
-
Cellular defences destroyed
-
D.W. Choi Cellular defences destroyed Nature 433 2005 696 698
-
(2005)
Nature
, vol.433
, pp. 696-698
-
-
Choi, D.W.1
-
28
-
-
0027021442
-
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
-
N.W. Soong, D.R. Hinton, G. Cortopassi, and N. Arnheim Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain Nat Genet 2 1992 318 323
-
(1992)
Nat Genet
, vol.2
, pp. 318-323
-
-
Soong, N.W.1
Hinton, D.R.2
Cortopassi, G.3
Arnheim, N.4
-
29
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
-
M. Corral-Debrinski, T. Horton, M.T. Lott, J.M. Shoffner, M.F. Beal, and D.C. Wallace Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age Nat Genet 2 1992 324 329
-
(1992)
Nat Genet
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
Beal, M.F.5
Wallace, D.C.6
-
30
-
-
0027438888
-
Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells
-
W.J. Driggers, S.P. LeDoux, and G.L. Wilson Repair of oxidative damage within the mitochondrial DNA or RINr 38 cells J Biol Chem 268 1993 22042 22045 (Pubitemid 23320713)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.29
, pp. 22042-22045
-
-
Driggers, W.J.1
LeDoux, S.P.2
Wilson, G.L.3
-
31
-
-
16844369889
-
Nuclear and mitochondrial DNA repair: Similar pathways?
-
DOI 10.1016/j.mito.2005.02.002, PII S1567724905000334
-
N.B. Larsen, M. Rasmussen, and L.J. Rasmussen Nuclear and mitochondrial DNA repair: similar pathways? Mitochondrion 5 2005 89 108 (Pubitemid 40485769)
-
(2005)
Mitochondrion
, vol.5
, Issue.2
, pp. 89-108
-
-
Larsen, N.B.1
Rasmussen, M.2
Rasmussen, L.J.3
-
32
-
-
0141480060
-
Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases
-
DOI 10.1073/pnas.1932854100
-
B. Szczesny, T.K. Hazra, J. Papaconstantinou, S. Mitra, and I. Boldogh Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases Proc Natl Acad Sci USA 100 2003 10670 10675 (Pubitemid 37140086)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.19
, pp. 10670-10675
-
-
Szczesny, B.1
Hazra, T.K.2
Papaconstantinou, J.3
Mitra, S.4
Boldogh, I.5
-
33
-
-
0030587492
-
Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase γ
-
DOI 10.1006/geno.1996.0490
-
P.A. Popp, and W.C. Copeland Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase gamma Genomics 36 1996 449 458 (Pubitemid 26321967)
-
(1996)
Genomics
, vol.36
, Issue.3
, pp. 449-458
-
-
Ropp, P.A.1
Copeland, W.C.2
-
34
-
-
0842269058
-
Cargo-Carrying Motor Vehicles on the Neuronal Highway: Transport Pathways and Neurodegenerative Disease
-
DOI 10.1002/neu.10319
-
S. Gunawardena, and L.S.B. Goldstein Cargo-carrying motor vehicles on the neuronal highway: transport pathways and neurodegenerative disease J Neurobiol 58 2003 258 271 (Pubitemid 38173723)
-
(2004)
Journal of Neurobiology
, vol.58
, Issue.2
, pp. 258-271
-
-
Gunawardena, S.1
Goldstein, L.S.B.2
-
35
-
-
0037933255
-
Mitochondrial movement and positioning in axons: The role of growth factor signaling
-
DOI 10.1242/jeb.00263
-
S.R. Chada, and P.J. Hollenbeck Mitochondrial movement and positioning in axons: the role of growth factor signaling J Exp Biol 206 2003 1985 1992 (Pubitemid 36761801)
-
(2003)
Journal of Experimental Biology
, vol.206
, Issue.12
, pp. 1985-1992
-
-
Chada, S.R.1
Hollenbeck, P.J.2
-
36
-
-
0032568790
-
Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria
-
DOI 10.1016/S0092-8674(00)81459-2
-
Y. Tanaka, Y. Kanai, Y. Okada, S. Nonaka, S. Takeda, and A. Harada Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria Cell 93 1998 1147 1158 (Pubitemid 28307420)
-
(1998)
Cell
, vol.93
, Issue.7
, pp. 1147-1158
-
-
Tanaka, Y.1
Kanai, Y.2
Okada, Y.3
Nonaka, S.4
Takeda, S.5
Harada, A.6
Hirokawa, N.7
-
37
-
-
0034694152
-
Role of microtubules and actin filaments in the movement of mitochondria in the axons and dendrites of cultured hippocampal neurons
-
L.A. Ligon, and O. Steward Role of microtubules and actin filaments in the movement of mitochondria in the axons and dendrites of cultured hippocampal neurons J Comp Neurol 427 2000 351 361
-
(2000)
J Comp Neurol
, vol.427
, pp. 351-361
-
-
Ligon, L.A.1
Steward, O.2
-
38
-
-
0041819756
-
Glutamate decreases mitochondrial size and movement in primary forebrain neurons
-
G.L. Pintoul, A.J. Filiano, J.B. Brocard, G.J. Kress, and I.J. Reynolds Glutamate decreases mitochondrial size and movement in primary forebrain neurons J Neurosci 23 2003 7881 7888 (Pubitemid 37052356)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.21
, pp. 7881-7888
-
-
Rintoul, G.L.1
Filiano, A.J.2
Brocard, J.B.3
Kress, G.J.4
Reynolds, I.J.5
-
39
-
-
10244241835
-
Mitochondrial trafficking in neurons: A key variable in neurodegeneration?
-
DOI 10.1023/B:JOBB.0000041754.78313.c2
-
I.J. Reynolds, L.M. Malaiyandi, M. Coash, and G.L. Rintoul Mitochondrial trafficking in neurons: a key variable in neurodegeneration? J Bioeng Biomembr 36 2004 283 286 (Pubitemid 39619827)
-
(2004)
Journal of Bioenergetics and Biomembranes
, vol.36
, Issue.4 SPEC. ISSUE
, pp. 283-286
-
-
Reynolds, I.J.1
Malaiyandi, L.M.2
Coash, M.3
Rintoul, G.L.4
-
40
-
-
3242875557
-
Axonal mitochondrial transport and potential are correlated
-
DOI 10.1242/jcs.01130
-
K.E. Miller, and M.P. Sheetz Axonal mitochondrial transport and potential are correlated J Cell Sci 117 2004 2791 2804 (Pubitemid 38997261)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2791-2804
-
-
Miller, K.E.1
Sheetz, M.P.2
-
41
-
-
2342425038
-
Role of tau phosphorylation by glycogen synthase kinase-3β in the regulation of organelle transport
-
DOI 10.1242/jcs.01018
-
Y. Tatebayashi, N. Haque, Y.C. Tung, K. Iqbal, and I. Grundke-Iqbal Role of tau phosphorylation by glycogen synthase kinase-3β in the regulation of organelle transport J Cell Sci 117 2004 1653 1663 (Pubitemid 38559298)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.9
, pp. 1653-1663
-
-
Tatebayashi, Y.1
Haque, N.2
Tung, Y.-C.3
Iqbal, K.4
Grundke-Iqbal, I.5
-
42
-
-
0035348408
-
Neuronal cell death in nervous system development, disease, and injury
-
L.J. Martin Neuronal cell death in nervous system development, disease, and injury Int J Mol Med 7 2001 455 478
-
(2001)
Int J Mol Med
, vol.7
, pp. 455-478
-
-
Martin, L.J.1
-
43
-
-
0036897873
-
Caspase-independent cell deaths
-
DOI 10.1016/S0955-0674(02)00383-6
-
R.A. Lockshin, and Z. Zakeri Caspase-independent cell deaths Curr Opin Cell Biol 14 2002 727 733 (Pubitemid 35449385)
-
(2002)
Current Opinion in Cell Biology
, vol.14
, Issue.6
, pp. 727-733
-
-
Lockshin, R.A.1
Zakeri, Z.2
-
45
-
-
0036311492
-
On the origin, evolution, and nature of programmed cell death: A timeline of four billion years
-
DOI 10.1038/sj.cdd.4400950
-
J.C. Ameisen On the origin, evolution, and nature of programmed cell death: a timeline of four billion years Cell Death Differ 9 2002 367 393 (Pubitemid 34822817)
-
(2002)
Cell Death and Differentiation
, vol.9
, Issue.4
, pp. 367-393
-
-
Ameisen, J.C.1
-
46
-
-
0031731989
-
Genetics of programmed cell death in C. elegans: Past, present and future
-
DOI 10.1016/S0168-9525(98)01573-X
-
M.M. Metzstein, G.M. Stanfield, and H.R. Horvitz Genetics of programmed cell death in C. elegans: past, present and future Trends Genet 14 1998 410 416 (Pubitemid 28505585)
-
(1998)
Trends in Genetics
, vol.14
, Issue.10
, pp. 410-416
-
-
Metzstein, M.M.1
Stanfield, G.M.2
Horvitz, H.R.3
-
47
-
-
37549048249
-
The Bcl-2 protein family: Opposing activities that mediate cell death
-
R.J. Youle, and A. Strasser The Bcl-2 protein family: opposing activities that mediate cell death Nat Rev 9 2008 47 59
-
(2008)
Nat Rev
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
48
-
-
0031057656
-
Bcl-2 gene family in the nervous system
-
D.E. Merry, and S.J. Korsmeyer Bcl-2 gene family in the nervous system Annu Rev Neurosci 20 1997 245 267
-
(1997)
Annu Rev Neurosci
, vol.20
, pp. 245-267
-
-
Merry, D.E.1
Korsmeyer, S.J.2
-
49
-
-
0036716281
-
The BCL2 family: Regulators of the cellular life-or-death switch
-
DOI 10.1038/nrc883
-
S. Cory, and J.M. Adams The bcl-2 family: regulators of the cellular life-or-death switch Nat Rev 2 2002 647 656 (Pubitemid 37328916)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.9
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
50
-
-
0033575255
-
Suicidal tendencies: Apoptotic cell death by caspase family proteinases
-
B.B. Wolf, and D.R. Green Suicidal tendencies: apoptotic cell death by caspase family proteinases J Biol Chem 274 1999 20049 20052
-
(1999)
J Biol Chem
, vol.274
, pp. 20049-20052
-
-
Wolf, B.B.1
Green, D.R.2
-
51
-
-
0033396491
-
Fas ligand-induced apoptosis
-
DOI 10.1146/annurev.genet.33.1.29
-
S. Nagata Fas ligand-induced apoptosis Annu Rev Genet 33 1999 29 55 (Pubitemid 30083118)
-
(1999)
Annual Review of Genetics
, vol.33
, pp. 29-55
-
-
Nagata, S.1
-
52
-
-
0034079520
-
The p53/p63/p73 family of transcription factors: Overlapping and distinct functions
-
M. Levrero, V. De Laurenzi, A. Costanzo, S. Sabatini, J. Gong, and J.Y.J. Wang The p53/p63/p73 family of transcription factors: overlapping and distinct functions J Cell Sci 113 2000 1661 1670 (Pubitemid 30333115)
-
(2000)
Journal of Cell Science
, vol.113
, Issue.10
, pp. 1661-1670
-
-
Levrero, M.1
De Laurenzi, V.2
Costanzo, A.3
Sabatini, S.4
Gong, J.5
Wang, J.Y.J.6
Melino, G.7
-
53
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
P. Li, D. Nijhawan, I. Budihardjo, S.M. Srinivasula, M. Ahmad, and E.S. Alnemri Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade Cell 91 1997 479 489 (Pubitemid 27508237)
-
(1997)
Cell
, vol.91
, Issue.4
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
54
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
DOI 10.1016/S0092-8674(00)80085-9
-
X. Liu, C.N. Kim, J. Yang, R. Jemmerson, and X. Wang Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c Cell 86 1996 147 157 (Pubitemid 26256586)
-
(1996)
Cell
, vol.86
, Issue.1
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
55
-
-
0037179691
-
The harlequin mouse mutation downregulates apoptosis-inducing factor
-
J.A. Klein, C.M. Longo-Guess, M.P. Rossmann, R.E. Seburn, R.E. Hurd, and W.N. Frankel The harlequin mouse mutation downregulates apoptosis-inducing factor Nature 419 2002 367 374
-
(2002)
Nature
, vol.419
, pp. 367-374
-
-
Klein, J.A.1
Longo-Guess, C.M.2
Rossmann, M.P.3
Seburn, R.E.4
Hurd, R.E.5
Frankel, W.N.6
-
56
-
-
18544386724
-
Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
-
R. Hegde, S.M. Srinivasula, Z. Zhang, R. Wassell, R. Mukattash, and L. Cilentei Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction J Biol Chem 277 2002 432 4538
-
(2002)
J Biol Chem
, vol.277
, pp. 432-4538
-
-
Hegde, R.1
Srinivasula, S.M.2
Zhang, Z.3
Wassell, R.4
Mukattash, R.5
Cilentei, L.6
-
57
-
-
13344278692
-
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
-
DOI 10.1038/379349a0
-
P. Liston, N. Roy, K. Tamai, C. Lefebvre, S. Baird, and G. Cherton-Horvat Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes Nature 379 1996 349 353 (Pubitemid 26033078)
-
(1996)
Nature
, vol.379
, Issue.6563
, pp. 349-353
-
-
Liston, P.1
Roy, N.2
Tamai, K.3
Lefebvre, C.4
Baird, S.5
Cherton-Horvat, G.6
Farahani, R.7
McLean, M.8
Ikeda, J.-E.9
MacKenzie, A.10
Korneluk, R.G.11
-
58
-
-
0037418843
-
2+ : A control point for apoptosis
-
DOI 10.1126/science.1081208
-
2 + : a control point for apoptosis Science 300 2003 135 139 (Pubitemid 36423046)
-
(2003)
Science
, vol.300
, Issue.5616
, pp. 135-139
-
-
Scorrano, L.1
Oakes, S.A.2
Opferman, J.T.3
Cheng, E.H.4
Sorcinelli, M.D.5
Pozzan, T.6
Korsmeyer, S.J.7
-
59
-
-
5244224827
-
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
-
S.W. Muchmore, M. Sattler, H. Liang, R.P. Meadows, J.E. Harlan, and H.S. Yoon X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death Nature 381 1999 335 341
-
(1999)
Nature
, vol.381
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
Meadows, R.P.4
Harlan, J.E.5
Yoon, H.S.6
-
60
-
-
9844257587
-
Inhibition of Bax channel-forming activity by Bcl-2
-
DOI 10.1126/science.277.5324.370
-
B. Antonsson, F. Conti, A. Ciavatta, S. Montessuit, S. Lewis, and I. Martinou Inhibition of bax channel-forming activity by bcl-2 Science 277 1997 370 372 (Pubitemid 27450709)
-
(1997)
Science
, vol.277
, Issue.5324
, pp. 370-372
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
Montessuit, S.4
Lewis, S.5
Martinou, I.6
Bernasconi, L.7
Bernard, A.8
Mermod, J.-J.9
Mazzei, G.10
Maundrell, K.11
Gambale, F.12
Sadoul, R.13
Martinou, J.-C.14
-
61
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
DOI 10.1016/S1535-6108(02)00127-7
-
A. Letai, M.C. Bassik, L.D. Walensky, M.D. Sorcinelli, S. Weiler, and S.J. Korsmeyer Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics Cancer Cell 2 2002 183 192 (Pubitemid 41043974)
-
(2002)
Cancer Cell
, vol.2
, Issue.3
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
62
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
DOI 10.1126/science.1059108
-
M.C. Wei, W.-X. Zong, E.H.-Y. Cheng, T. Lindsten, V. Panoutsakopoulou, and A.J. Ross Proapoptotic Bax and Bak: a requisite gateway to mitochondrial dysfunction and death Science 292 2001 727 730 (Pubitemid 32385543)
-
(2001)
Science
, vol.292
, Issue.5517
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.-X.2
Cheng, E.H.-Y.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
Macgregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
63
-
-
0034697365
-
Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c
-
DOI 10.1074/jbc.275.16.12321
-
S. Shimizu, T. Ide, T. Yanagida, and Y. Tsujimoto Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c J Biol Chem 275 2000 12321 12325 (Pubitemid 30237814)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.16
, pp. 12321-12325
-
-
Shimizu, S.1
Ide, T.2
Yanagida, T.3
Tsujimoto, Y.4
-
65
-
-
0032559799
-
The caspase-3 precursor has a cytosolic and mitochondrial distribution: Implications for apoptotic signaling
-
DOI 10.1083/jcb.140.6.1485
-
M. Mancini, D.W. Nicholson, S. Roy, N.A. Thornberry, E.P. Peterson, and L.A. Casciola-Rosen The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling J Cell Biol 140 1998 1485 1495 (Pubitemid 28152996)
-
(1998)
Journal of Cell Biology
, vol.140
, Issue.6
, pp. 1485-1495
-
-
Mancini, M.1
Nicholson, D.W.2
Roy, S.3
Thornberry, N.A.4
Peterson, E.P.5
Casciola-Rosen, L.A.6
Rosen, A.7
-
66
-
-
13044305983
-
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia
-
DOI 10.1073/pnas.96.10.5752
-
S. Krajewski, M. Krajewska, L.M. Ellerby, K. Welsh, Z. Xie, and Q.L. Deveraus Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia Proc Natl Acad Sci USA 96 1999 5752 5757 (Pubitemid 29234690)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.10
, pp. 5752-5757
-
-
Krajewski, S.1
Krajewska, M.2
Ellerby, L.M.3
Welsh, K.4
Xie, Z.5
Deveraux, Q.L.6
Salvesen, G.S.7
Bredesen, D.E.8
Rosenthal, R.E.9
Fiskum, G.10
Reed, J.C.11
-
67
-
-
0030916417
-
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
X. Liu, H. Zou, C. Slaughter, and X. Wang DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis Cell 89 1997 175 184 (Pubitemid 27199890)
-
(1997)
Cell
, vol.89
, Issue.2
, pp. 175-184
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
68
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
H. Li, H. Zhu, C.-J. Xu, and J. Yuan Cleavage of Bid by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis Cell 94 1998 491 501 (Pubitemid 28391865)
-
(1998)
Cell
, vol.94
, Issue.4
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.-J.3
Yuan, J.4
-
69
-
-
0037119491
-
Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis
-
J.D. Robertson, M. Enoksson, M. Suomela, B. Zhivotovsky, and S. Orrenius Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis J Biol Chem 277 2002 29803 29809
-
(2002)
J Biol Chem
, vol.277
, pp. 29803-29809
-
-
Robertson, J.D.1
Enoksson, M.2
Suomela, M.3
Zhivotovsky, B.4
Orrenius, S.5
-
70
-
-
0032410818
-
The inhibitors of apoptosis (IAPs) and their emerging role in cancer
-
E.C. LaCasse, S. Baird, R.G. Korneluk, and A.E. MacKenzie The inhibitors of apoptosis (IAPs) and their emerging role in cancer Oncogene 17 1998 3247 3259 (Pubitemid 29043977)
-
(1998)
Oncogene
, vol.17
, Issue.25
, pp. 3247-3259
-
-
LaCasse, E.C.1
Baird, S.2
Korneluk, R.G.3
MacKenzie, A.E.4
-
71
-
-
0036803293
-
The IAP proteins
-
DOI 10.1016/S0168-9525(02)02743-9, PII S0168952502027439
-
M. Holcik The IAP proteins Trends Genet 18 2002 537 538 (Pubitemid 35287029)
-
(2002)
Trends in Genetics
, vol.18
, Issue.10
, pp. 537-538
-
-
Holcik, M.1
-
72
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
DOI 10.1093/emboj/17.8.2215
-
Q.L. Deveraux, N. Roy, H.R. Stennicke, T. Van Arsdale, Q. Zhou, and S.M. Srinivasula IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases EMBO J 17 1998 2215 2223 (Pubitemid 28171907)
-
(1998)
EMBO Journal
, vol.17
, Issue.8
, pp. 2215-2223
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
Van Arsdale, T.4
Zhou, Q.5
Srinivasula, S.M.6
Alnemri, E.S.7
Salvesen, G.S.8
Reed, J.C.9
-
73
-
-
4444329609
-
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
-
DOI 10.1038/ncb1159
-
Y. Hao, K. Sekine, A. Kawabata, H. Nakamura, T. Ishioka, and H. Ohata Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function Nat Cell Biol 6 2004 849 860 (Pubitemid 39207250)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.9
, pp. 849-860
-
-
Hao, Y.1
Sekine, K.2
Kawabata, A.3
Nakamura, H.4
Ishioka, T.5
Ohata, H.6
Katayama, R.7
Hashimoto, C.8
Zhang, X.9
Noda, T.10
Tsuruo, T.11
Naito, M.12
-
74
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
C. Du, M. Fang, Y. Li, L. Li, and X. Wang Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition Cell 102 2000 33 42
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
75
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
A.M. Verhagen, P.G. Ekert, M. Pakusch, J. Silke, L.M. Connolly, and G.E. Reid Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins Cell 102 2000 43 53
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
-
76
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
DOI 10.1016/S1097-2765(01)00341-0
-
Y. Suzuki, Y. Imai, H. Nakayama, K. Takahashi, K. Takio, and R. Takahashi A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death Mol Cell 8 2001 613 621 (Pubitemid 32946938)
-
(2001)
Molecular Cell
, vol.8
, Issue.3
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
77
-
-
44849115171
-
Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease
-
DOI 10.1002/humu.20713
-
V. Bogaerts, K. Nuytemans, J. Reumers, R. Pals, S. Engelborghs, and B. Pickut Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson's disease Hum Mutat 29 2008 832 840 (Pubitemid 351794134)
-
(2008)
Human Mutation
, vol.29
, Issue.6
, pp. 832-840
-
-
Bogaerts, V.1
Nuytemans, K.2
Reumers, J.3
Pals, P.4
Engelborghs, S.5
Pickut, B.6
Corsmit, E.7
Peeters, K.8
Schymkowitz, J.9
De Deyn, P.P.10
Cras, P.11
Rousseau, F.12
Theuns, J.13
Van Broeckhoven, C.14
-
78
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
S.A. Susin, H.K. Lorenzo, N. Zamzami, I. Marzo, B.E. Snow, and G.M. Brothers Molecular characterization of mitochondrial apoptosis-inducing factor Nature 397 1999 441 446
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
-
79
-
-
0036263870
-
The crystal structure of the mouse apoptosis-inducing factor AIF
-
DOI 10.1038/nsb793
-
M.J. Mate, M. Ortiz-Lombardia, B. Boitel, A. Haouz, D. Tello, and S.A. Susin The crystal structure of the mouse apoptosis-inducing factor AIF Nat Struct Biol 9 2002 442 446 (Pubitemid 34568789)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.6
, pp. 442-446
-
-
Mate, M.J.1
Ortiz-Lombardia, M.2
Boitel, B.3
Haouz, A.4
Tello, D.5
Susin, S.A.6
Penninger, J.7
Kroemer, G.8
Alzari, P.M.9
-
81
-
-
0028891783
-
Apoptosis, oncosis, and necrosis. An overview of cell death
-
G. Majno, and I. Joris Apoptosis, oncosis, and necrosis. An overview of cell death Am J Pathol 146 1995 3 15
-
(1995)
Am J Pathol
, vol.146
, pp. 3-15
-
-
Majno, G.1
Joris, I.2
-
82
-
-
0042485265
-
Studies on necrosis of mouse liver in vitro. Ultrastructural alterations in the mitochondria of hepatic parenchymal cells
-
B.J. Trump, P.J. Goldblatt, and R.E. Stowell Studies on necrosis of mouse liver in vitro. Ultrastructural alterations in the mitochondria of hepatic parenchymal cells Lab Invest 14 1964 343 371
-
(1964)
Lab Invest
, vol.14
, pp. 343-371
-
-
Trump, B.J.1
Goldblatt, P.J.2
Stowell, R.E.3
-
83
-
-
0029153913
-
Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell culture
-
E. Bonfoco, D. Krainc, M. Ankarcrona, P. Nicotera, and S.A. Lipton Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell culture Proc Natl Acad Sci USA 92 1995 7162 7166
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7162-7166
-
-
Bonfoco, E.1
Krainc, D.2
Ankarcrona, M.3
Nicotera, P.4
Lipton, S.A.5
-
84
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
-
DOI 10.1084/jem.185.8.1481
-
M. Leist, B. Single, A.F. Castoldi, S. Kuhnles, and P. Nicotera Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis J Exp Med 185 1997 1481 1486 (Pubitemid 27187604)
-
(1997)
Journal of Experimental Medicine
, vol.185
, Issue.8
, pp. 1481-1486
-
-
Leist, M.1
Single, B.2
Castoldi, A.F.3
Kuhnle, S.4
Nicotera, P.5
-
85
-
-
0035977978
-
Failure to sustain recovery of Na,K-ATPase function is a possible mechanism for striatal neurodegeneration in hypoxic-ischemic newborn piglets
-
DOI 10.1016/S0169-328X(01)00032-8, PII S0169328X01000328
-
W.C. Golden, A.M. Brambrink, R.J. Traystman, and L.J. Martin Failure to sustain recovery of Na, K ATPase function is a possible mechanism for striatal neurodegeneration in hypoxic-ischemic newborn piglets Mol Brain Res 88 2001 94 102 (Pubitemid 32274263)
-
(2001)
Molecular Brain Research
, vol.88
, Issue.1-2
, pp. 94-102
-
-
Golden, W.C.1
Brambrink, A.M.2
Traystman, R.J.3
Martin, L.J.4
-
86
-
-
33748700613
-
2+ overload
-
DOI 10.1038/sj.cdd.4401852, PII 4401852
-
2 + overload Cell Death Differ 13 2006 1675 1685 (Pubitemid 44390855)
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.10
, pp. 1675-1685
-
-
Castro, J.1
Ruminot, I.2
Porras, O.H.3
Flores, C.M.4
Hermosilla, T.5
Verdugo, E.6
Venegas, F.7
Hartel, S.8
Michea, L.9
Barros, L.F.10
-
88
-
-
34249820757
-
TNF-Induced Activation of the Nox1 NADPH Oxidase and Its Role in the Induction of Necrotic Cell Death
-
DOI 10.1016/j.molcel.2007.04.021, PII S1097276507002584
-
Y.-S. Kim, M.J. Morgan, S. Choksi, and Z.-G. Lu TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death Mol Cell 26 2007 675 687 (Pubitemid 46856240)
-
(2007)
Molecular Cell
, vol.26
, Issue.5
, pp. 675-687
-
-
Kim, Y.-S.1
Morgan, M.J.2
Choksi, S.3
Liu, Z.-g.4
-
89
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
J. Hitomi, D.E. Christofferson, A. Ng, J. Yao, A. Degterev, and R.J. Xavier Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway Cell 135 2008 1311 1323
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
-
90
-
-
15844375853
-
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
-
DOI 10.1038/nature03434
-
C.P. Baines, R.A. Kaiser, N.H. Purcell, H.S. Blair, H. Osinska, and M.A. Hambleton Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death Nature 434 2005 658 662 (Pubitemid 40488559)
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 658-662
-
-
Baines, C.P.1
Kaiser, R.A.2
Purcell, N.H.3
Blair, N.S.4
Osinska, H.5
Hambleton, M.A.6
Brunskill, E.W.7
Sayen, M.R.8
Gottlieb, R.A.9
Dorn II, G.W.10
Bobbins, J.11
Molkentin, J.D.12
-
91
-
-
0033830186
-
Poly(ADP-ribose) polymerase-1 in the nervous system
-
H.C. Ha, and S.H. Snyder Poly(ADP-ribose) polymerase-1 in the nervous system Neurobiol Dis 7 2000 225 239
-
(2000)
Neurobiol Dis
, vol.7
, pp. 225-239
-
-
Ha, H.C.1
Snyder, S.H.2
-
92
-
-
0029116916
-
The mitochondrial permeability transition
-
M. Zoratti, and I. Szabo The mitochondrial permeability transition Biochem Biophys Acta 1241 1995 139 176
-
(1995)
Biochem Biophys Acta
, vol.1241
, pp. 139-176
-
-
Zoratti, M.1
Szabo, I.2
-
93
-
-
0033565557
-
The mitochondrial permeabitity transition pore and its role in cell death
-
DOI 10.1042/0264-6021:3410233
-
M. Crompton The mitochondrial permeability transition pore and its role in cell death Biochem J 341 1999 233 249 (Pubitemid 29373645)
-
(1999)
Biochemical Journal
, vol.341
, Issue.2
, pp. 233-249
-
-
Crompton, M.1
-
94
-
-
0037427444
-
Mitochondrial intermembrane proteins in cell death
-
DOI 10.1016/S0006-291X(03)00621-1
-
M. van Gurp, N. Festjens, G. van Loo, X. Saelens, and P. Vandenabeele Mitochondrial intermembrane proteins in cell death Biochem Biophys Res Commun 304 2003 487 497 (Pubitemid 36506521)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.304
, Issue.3
, pp. 487-497
-
-
Van Gurp, M.1
Festjens, N.2
Van Loo, G.3
Saelens, X.4
Vandenabeele, P.5
-
95
-
-
46349097952
-
Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore
-
A.W.C. Leung, and A.P. Halestrap Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore Biochim Biophys Acta 1777 2008 946 952
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 946-952
-
-
Leung, A.W.C.1
Halestrap, A.P.2
-
96
-
-
33745136102
-
The voltage-dependent anion channel (VDAC): Function in intracellular signalling, cell life and cell death
-
DOI 10.2174/138161206777585111
-
V. Shoshan-Barmatz, A. Israelson, D. Brdiczka, and S.S. Sheu The voltage-dependent anion channel (VDAC): function in intracellular signaling, cell life and cell death Curr Pharm Des 12 2006 2249 2270 (Pubitemid 43891398)
-
(2006)
Current Pharmaceutical Design
, vol.12
, Issue.18
, pp. 2249-2270
-
-
Shoshan-Barmatz, V.1
Israelson, A.2
Brdiczka, D.3
Sheu, S.S.4
-
98
-
-
34948846577
-
VDAC closure increases calcium ion flux
-
DOI 10.1016/j.bbamem.2007.06.002, PII S0005273607002131
-
W. Tan, and M. Colombini VDAC closure increases calcium ion flux Biochim Biophys Acta 1768 2007 2510 2515 (Pubitemid 47532032)
-
(2007)
Biochimica et Biophysica Acta - Biomembranes
, vol.1768
, Issue.10
, pp. 2510-2515
-
-
Tan, W.1
Colombini, M.2
-
100
-
-
0041810124
-
The mitochondrial voltage-dependent anion channel (VDAC) as a therapeutic target for initiating cell death
-
D.J. Granville, and R.A. Gottlieb The mitochondrial voltage-dependent anion channel (VDAC) as a therapeutic target for initiating cell death Curr Med Chem 10 2003 1527 1533 (Pubitemid 36896554)
-
(2003)
Current Medicinal Chemistry
, vol.10
, Issue.16
, pp. 1527-1533
-
-
Granville, D.J.1
Gottlieb, R.A.2
-
101
-
-
0031783363
-
Human mitochondrial transmembrane metabolite carriers: Tissue distribution and its implication for mitochondrial disorders
-
M. Huizing, W. Ruitenbeek, L.P. van den Heuvel, V. Dolce, V. Iacobazzi, and J.A.M. Smeitink Human mitochondrial transmembrane metabolite carriers: tissue distribution and its implication for mitochondrial disorders J Bioenerg Biomembr 30 1998 277 284 (Pubitemid 28405169)
-
(1998)
Journal of Bioenergetics and Biomembranes
, vol.30
, Issue.3
, pp. 277-284
-
-
Huizing, M.1
Ruitenbeek, W.2
Van Den Heuvel, L.P.3
Dolce, V.4
Iacobazzi, V.5
Smeitink, J.A.M.6
Palmieri, F.7
Frans Trijbels, J.M.8
-
102
-
-
0032852959
-
Each mammalian mitochondrial outer membrane porin protein is dispensable: Effects on cellular respiration
-
DOI 10.1016/S0167-4889(99)00120-2, PII S0167488999001202
-
S. Wu, M.J. Sampson, W.K. Decker, and W.J. Craigen Each mammalian mitochondrial outer membrane porin protein is dispensable: effects on cellular respiration Biochem Biophys Acta 1452 1999 68 78 (Pubitemid 29486743)
-
(1999)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1452
, Issue.1
, pp. 68-78
-
-
Wu, S.1
Sampson, M.J.2
Decker, W.K.3
Craigen, W.J.4
-
103
-
-
0035910495
-
Altered mitochondrial sensitivity for ADP and maintenance of creatine-stimulated respiration in oxidative striated muscles from VDAC1-deficient mice
-
DOI 10.1074/jbc.M006587200
-
K. Anflous, D.D. Armstrong, and W.J. Craigen Altered sensitivity for ADP and maintenance of creatine-stimulated respiration in oxidative striated muscles from VDAC1-deficient mice J Biol Chem 276 2001 1954 1960 (Pubitemid 32109673)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.3
, pp. 1954-1960
-
-
Anflous, K.1
Armstrong, D.D.2
Craigen, W.J.3
-
104
-
-
0035914399
-
Immotile sperm and infertility in mice lacking mitochondrial voltage-dependent anion channel type 3
-
M.J. Sampson, W.K. Decker, A.L. Beaudet, W. Ruitenbeek, D. Armstrong, and M.J. Hicks Immotile sperm and infertility in mice lacking mitochondrial voltage-dependent anion channel type 3 J Biol Chem 276 2001 39206 39212
-
(2001)
J Biol Chem
, vol.276
, pp. 39206-39212
-
-
Sampson, M.J.1
Decker, W.K.2
Beaudet, A.L.3
Ruitenbeek, W.4
Armstrong, D.5
Hicks, M.J.6
-
105
-
-
0043204996
-
VDAC2 inhibits BAK activation and mitochondrial apoptosis
-
DOI 10.1126/science.1083995
-
E.H. Cheng, T.V. Sheiko, J.K. Fisher, W.J. Craigen, and S.J. Korsemeyer VDAC2 inhibits Bak activation and mitochondrial apoptosis Science 301 2003 513 517 (Pubitemid 36900308)
-
(2003)
Science
, vol.301
, Issue.5632
, pp. 513-517
-
-
Cheng, E.H.-Y.1
Sheiko, T.V.2
Fisher, J.K.3
Craigen, W.J.4
Korsmeyer, S.J.5
-
106
-
-
21444443226
-
Bax-dependent regulation of Bak by voltage-dependent anion channel 2
-
DOI 10.1074/jbc.M501391200
-
D. Chandra, G. Choy, P.T. Daniel, and D.G. Tang Bax-dependent regulation of Bak by voltage-dependent anion channel 2 J Biol Chem 280 2005 19051 19061 (Pubitemid 41379611)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.19
, pp. 19051-19061
-
-
Chandra, D.1
Choy, G.2
Daniel, P.T.3
Tang, D.G.4
-
107
-
-
34247895697
-
Voltage-dependent anion channels are dispensable for mitochondrial- dependent cell death
-
DOI 10.1038/ncb1575, PII NCB1575
-
C.P. Baines, R.A. Kaiser, T. Sheiko, W.J. Craigen, and J.D. Molkentin Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death Nat Cell Biol 9 2007 550 555 (Pubitemid 46696536)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.5
, pp. 550-555
-
-
Baines, C.P.1
Kaiser, R.A.2
Sheiko, T.3
Craigen, W.J.4
Molkentin, J.D.5
-
108
-
-
58149489946
-
Cu, Zn-superoxide dismutase is necessary for proper function of VDAC in Saccharomyces cerevisiae cells
-
A. Karachitos, H. Galganska, M. Wojtkowska, M. Budzinska, O. Stobienia, and G. Bartosz Cu, Zn-superoxide dismutase is necessary for proper function of VDAC in Saccharomyces cerevisiae cells FEBS Lett 583 2009 449 455
-
(2009)
FEBS Lett
, vol.583
, pp. 449-455
-
-
Karachitos, A.1
Galganska, H.2
Wojtkowska, M.3
Budzinska, M.4
Stobienia, O.5
Bartosz, G.6
-
109
-
-
0041810128
-
The adenine nucleotide translocase: A central component of the mitochondrial permeability transition pore and key player in cell death
-
A.P. Halestrap, and C. Brenner The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death Curr Med Chem 10 2003 1507 1525 (Pubitemid 36896553)
-
(2003)
Current Medicinal Chemistry
, vol.10
, Issue.16
, pp. 1507-1525
-
-
Halestrap, A.P.1
Brenner, C.2
-
110
-
-
0031011211
-
A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator
-
DOI 10.1038/ng0797-226
-
B.H. Graham, K.G. Waymire, B. Cottrell, I.A. Trounce, G.R. MacGregor, and D.C. Wallace A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator Nat Genet 16 1997 226 234 (Pubitemid 27280204)
-
(1997)
Nature Genetics
, vol.16
, Issue.3
, pp. 226-234
-
-
Graham, B.H.1
Waymire, K.G.2
Cottrell, B.3
Trounce, I.A.4
MacGregor, G.R.5
Wallace, D.C.6
-
111
-
-
0026718789
-
Differential expression of adenine nucleotide translocator isoforms in mammalian tissues and during muscle cell differentiation
-
G. Stepien, A. Torroni, A.B. Chung, J.A. Hodge, and D.C. Wallace Differential expression of adenine nucleotide translocator isoforms in mammalian tissues and during muscle cell differentiation J Biol Chem 267 1992 14592 14597
-
(1992)
J Biol Chem
, vol.267
, pp. 14592-14597
-
-
Stepien, G.1
Torroni, A.2
Chung, A.B.3
Hodge, J.A.4
Wallace, D.C.5
-
112
-
-
0035448294
-
Adenine nucleotide translocator isoforms 1 and 2 are differently distributed in the mitochondrial inner membrane and have distinct affinities to cyclophilin D
-
DOI 10.1042/0264-6021:3580349
-
M.Y. Vyssokikh, A. Katz, A. Rueck, C. Wuensch, A. Dorner, and D.B. Zorov Adenine nucleotide translocator isoforms 1 and 2 are differently distributed in the mitochondrial inner membrane and have distinct affinities to cyclophilin D Biochem J 358 2001 349 358 (Pubitemid 32826351)
-
(2001)
Biochemical Journal
, vol.358
, Issue.2
, pp. 349-358
-
-
Vyssokikh, M.Y.1
Katz, A.2
Rueck, A.3
Wuensch, C.4
Dorner, A.5
Zorov, D.B.6
Brdiczka, D.7
-
113
-
-
0842307483
-
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
-
DOI 10.1038/nature02229
-
J.E. Kikoszka, K.G. Waymire, S.E. Levy, J.E. Sligh, J. Cai, and D.P. Jones The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore Nature 427 2004 461 465 (Pubitemid 38168501)
-
(2004)
Nature
, vol.427
, Issue.6973
, pp. 461-465
-
-
Kokoszka, J.E.1
Waymire, K.G.2
Levy, S.E.3
Sligh, J.E.4
Cai, J.5
Jones, D.P.6
MacGregor, G.R.7
Wallace, D.C.8
-
114
-
-
0037163114
-
A novel adenine nucleotide translocase inhibitor, MT-21, induces cytochrome c release by a mitochondrial permeability transition-independent mechanism
-
DOI 10.1074/jbc.M204564200
-
K. Machida, Y. Hayashi, and H. Osada A novel adenine nucleotide translocase inhibitor, MT-21, induces cytochrome c release through a mitochondrial permeability transition-independent mechanisms J Biol Chem 277 2002 31243 31248 (Pubitemid 34970832)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.34
, pp. 31243-31248
-
-
Machida, K.1
Hayashi, Y.2
Osada, H.3
-
115
-
-
0032387842
-
Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition
-
K. Woodfield, A. Rück, D. Brdiczka, and A.P. Halestrap Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition Biochem J 336 1998 287 290 (Pubitemid 28564382)
-
(1998)
Biochemical Journal
, vol.336
, Issue.2
, pp. 287-290
-
-
Woodfield, K.1
Ruck, A.2
Brdiczka, D.3
Halestrap, A.P.4
-
116
-
-
0033565965
-
Import and processing of heart mitochondrial cyclophilin D
-
DOI 10.1046/j.1432-1327.1999.00490.x
-
N. Johnson, A. Khan, S. Virji, J.M. Ward, and M. Crompton Import and processing of heart mitochondrial cyclophilin D Eur J Biochem 263 1999 353 359 (Pubitemid 29337025)
-
(1999)
European Journal of Biochemistry
, vol.263
, Issue.2
, pp. 353-359
-
-
Johnson, N.1
Khan, A.2
Virji, S.3
Ward, J.M.4
Crompton, M.5
-
117
-
-
0027453499
-
Mitochondrial voltage-dependent anion channel
-
M.W. McEnery, T.M. Dawson, A. Verma, D. Gurley, M. Colombini, and S.H. Snyder Mitochondrial voltage-dependent anion channel J Biol Chem 268 1993 23289 23296
-
(1993)
J Biol Chem
, vol.268
, pp. 23289-23296
-
-
McEnery, M.W.1
Dawson, T.M.2
Verma, A.3
Gurley, D.4
Colombini, M.5
Snyder, S.H.6
-
118
-
-
3242728582
-
Subcellular localization of VDAC in mitochondria and ER in the cerebellum
-
DOI 10.1016/j.bbabio.2004.02.009, PII S000527280400043X
-
V. Shoshan-Barmatz, R. Zalk, D. Gincel, and N. Vardi Subcellular localization of VDAC in mitochondria and ER in the cerebellum Biochem Biophys Acta 1657 2004 105 114 (Pubitemid 38952871)
-
(2004)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1657
, Issue.2-3
, pp. 105-114
-
-
Shoshan-Barmatz, V.1
Zalk, R.2
Gincel, D.3
Vardi, N.4
-
119
-
-
54049158483
-
Voltage-dependent anion channels (VDAC) in the plasma membrane play a critical role in apoptosis in differentiated hippocampal neurons but not in neural stem cells
-
N. Akanda, R. Tofight, J. Brask, C. Tamm, F. Elinder, and S. Ceccatelli Voltage-dependent anion channels (VDAC) in the plasma membrane play a critical role in apoptosis in differentiated hippocampal neurons but not in neural stem cells Cell Cycle 7 2008 3225 3234
-
(2008)
Cell Cycle
, vol.7
, pp. 3225-3234
-
-
Akanda, N.1
Tofight, R.2
Brask, J.3
Tamm, C.4
Elinder, F.5
Ceccatelli, S.6
-
120
-
-
0029040549
-
Subcellular localization of human voltage-dependent anion channel isoforms
-
W.H. Yu, W. Wolfgang, and M. Forte Subcellular localization of human voltage-dependent anion channel isoforms J Biol Chem 270 1995 13998 14006
-
(1995)
J Biol Chem
, vol.270
, pp. 13998-14006
-
-
Yu, W.H.1
Wolfgang, W.2
Forte, M.3
-
121
-
-
0038237355
-
Increased adenine nucleotide translocator 1 in reactive astrocytes facilitates glutamate transport
-
DOI 10.1016/S0014-4886(03)00043-8
-
C.R. Buck, M.J. Jurynec, D.E. Upta, A.K.T. Law, J. Bilger, and D.C. Wallace Increased adenine nucleotide translocator 1 in reactive astrocytes facilitates glutamate transport Exp Neurol 181 2003 149 158 (Pubitemid 36629236)
-
(2003)
Experimental Neurology
, vol.181
, Issue.2
, pp. 149-158
-
-
Buck, C.R.1
Jurynec, M.J.2
Gupta, D.K.3
Law, A.K.T.4
Bilger, J.5
Wallace, D.C.6
McKeon, R.J.7
-
122
-
-
65649128952
-
Cyclophilin D is expressed predominantly in mitochondria of γ-aminobutyric acidergic interneurons
-
J.L. Hazelton, M. Petrasheuskaya, G. Fiskum, and T. Kristian Cyclophilin D is expressed predominantly in mitochondria of γ-aminobutyric acidergic interneurons J Neurosci Res 87 2009 1250 1259
-
(2009)
J Neurosci Res
, vol.87
, pp. 1250-1259
-
-
Hazelton, J.L.1
Petrasheuskaya, M.2
Fiskum, G.3
Kristian, T.4
-
123
-
-
34447498864
-
High cyclophilin D content of synaptic mitochondria results in increased vulnerability to permeability transition
-
DOI 10.1523/JNEUROSCI.0646-07.2007
-
K.K. Naga, P.G. Sullivan, and J.W. Geddes High cyclophilin D content of synaptic mitochondria results in increased vulnerability to permeability transition J Neurosci 27 2007 7469 7475 (Pubitemid 47066566)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.28
, pp. 7469-7475
-
-
Naga, K.K.1
Sullivan, P.G.2
Geddes, J.W.3
-
124
-
-
67649811029
-
The mitochondrial permeability transition pore in motor neurons: Involvement in the pathobiology of ALS mice
-
L.J. Martin, B. Gertz, Y. Pan, A.C. Price, J.D. Molkentin, and Q. Chang The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice Exp Neurol 218 2009 333 346
-
(2009)
Exp Neurol
, vol.218
, pp. 333-346
-
-
Martin, L.J.1
Gertz, B.2
Pan, Y.3
Price, A.C.4
Molkentin, J.D.5
Chang, Q.6
-
125
-
-
0028336648
-
Peptidyl prolyl cis-trans-isomerase activity associated with the lumen of the endoplasmic reticulum
-
S. Bose, and R.B. Freedman Peptidyl prolyl cis-trans-isomerase activity associated with the lumen of the endoplasmic reticulum Biochem J 300 1994 865 870 (Pubitemid 24180605)
-
(1994)
Biochemical Journal
, vol.300
, Issue.3
, pp. 865-870
-
-
Bose, S.1
Freedman, R.B.2
-
126
-
-
2642532860
-
Intrinsic differences in brain and spinal cord mitochondria: Implication for therapeutic interventions
-
DOI 10.1002/cne.20130
-
P.G. Sullivan, A.G. Rabchevsky, J.N. Keller, M. Lovell, A. Sodhi, and R.P. Hart Intrinsic differences in brain and spinal cord mitochondria: implications for therapeutic interventions J Comp Neurol 474 2004 524 534 (Pubitemid 38720422)
-
(2004)
Journal of Comparative Neurology
, vol.474
, Issue.4
, pp. 524-534
-
-
Sullivan, P.G.1
Rabchevsky, A.G.2
Keller, J.N.3
Lovell, M.4
Sodhi, A.5
Hart, R.P.6
Scheff, S.W.7
-
127
-
-
36248984867
-
Spinal cord mitochondria display lower calcium retention capacity compared with brain mitochondria without inherent differences in sensitivity to cyclophilin D inhibition
-
DOI 10.1111/j.1471-4159.2007.04912.x
-
S. Morota, M.J. Hansson, N. Ishii, Y. Kudo, E. Elmer, and H. Uchino Spinal cord mitochondria display lower calcium retention capacity compared with brain mitochondria without inherent differences in sensitivity to cyclophilin D inhibition J Neurochem 103 2007 2066 2076 (Pubitemid 350126633)
-
(2007)
Journal of Neurochemistry
, vol.103
, Issue.5
, pp. 2066-2076
-
-
Morota, S.1
Hansson, M.J.2
Ishii, N.3
Kudo, Y.4
Elmer, E.5
Uchino, H.6
-
128
-
-
0038609470
-
Mitochondria are morphologically heterogeneous within cells
-
DOI 10.1242/jeb.00244
-
T.J. Collins, and M.D. Bootman Mitochondria are morphologically heterogeneous within cells J Exp Biol 206 2003 1993 2000 (Pubitemid 36761802)
-
(2003)
Journal of Experimental Biology
, vol.206
, Issue.12
, pp. 1993-2000
-
-
Collins, T.J.1
Bootman, M.D.2
-
129
-
-
22044432618
-
Control of mitochondrial shape
-
DOI 10.1016/j.ceb.2005.06.011, PII S0955067405000864, Membranes and Organelles
-
R.E. Jensen Control of mitochondrial shape Curr Opin Cell Biol 17 2005 384 388 (Pubitemid 40968068)
-
(2005)
Current Opinion in Cell Biology
, vol.17
, Issue.4
, pp. 384-388
-
-
Jensen, R.E.1
-
130
-
-
0014782488
-
Comparative studies of mitochondria isolated from neuron-enriched and glia-enriched fractions of rabbit and beef brain
-
A. Hamberger, C. Blomstrand, and A.L. Lehninger Comparative studies of mitochondria isolated from neuron-enriched and glia-enriched fractions of rabbit and beef brain J Cell Biol 45 1970 221 234
-
(1970)
J Cell Biol
, vol.45
, pp. 221-234
-
-
Hamberger, A.1
Blomstrand, C.2
Lehninger, A.L.3
-
131
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
DOI 10.1126/science.290.5497.1717
-
D.J. Klionsky, and S.D. Emr Autophagy as a regulated pathway of cellular degradation Science 290 2000 1717 1721 (Pubitemid 32004796)
-
(2000)
Science
, vol.290
, Issue.5497
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
132
-
-
0036479052
-
Mitochondrial disappearance from cells: A clue to the role of autophagy in programmed cell death and disease
-
A.M. Tolkovsky, L. Xue, G.C. Fletcher, and V. Borutaite Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease Biochimie 84 2002 233 240
-
(2002)
Biochimie
, vol.84
, pp. 233-240
-
-
Tolkovsky, A.M.1
Xue, L.2
Fletcher, G.C.3
Borutaite, V.4
-
133
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
DOI 10.1038/sj.onc.1207521
-
D. Gozuacik, and A. Kimchi Autophagy as a cell death and tumor suppressor mechanism Oncogene 23 2004 2891 2906 (Pubitemid 38638851)
-
(2004)
Oncogene
, vol.23
, Issue.16 REV. ISSUE 2
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
134
-
-
0032543714
-
Ultrastructural analysis of the progression of neurodegeneration in the septum following fimbria-fornix transection
-
DOI 10.1016/S0306-4522(98)00136-5, PII S0306452298001365
-
S.D. Ginsberg, and L.J. Martin Ultrastructural analysis of the progression of neurodegeneration in the septum following fimbria-fornix transaction Neuroscience 86 1998 1259 1272 (Pubitemid 28318550)
-
(1998)
Neuroscience
, vol.86
, Issue.4
, pp. 1259-1272
-
-
Ginsberg, S.D.1
Martin, L.J.2
-
135
-
-
0032890067
-
Fimbria-fornix transection and excitotoxicity produce similar neurodegeneration in the septum
-
DOI 10.1016/S0306-4522(98)00288-7, PII S0306452298002887
-
S.D. Ginsberg, C. Portera-Cailliau, and L.J. Martin Fimbria-fronix transection and excitotoxicity produce similar neurodegeneration in the septum Neuroscience 88 1999 1059 1071 (Pubitemid 28546989)
-
(1999)
Neuroscience
, vol.88
, Issue.4
, pp. 1059-1071
-
-
Ginsberg, S.D.1
Portera-Cailliau, C.2
Martin, L.J.3
-
136
-
-
0032864716
-
Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis
-
DOI 10.1002/(SICI)1097-4695(199908)40:2<185::AID-NEU5>3.0.CO;2-#
-
L.J. Martin, A. Kaiser, and A.C. Price Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis J Neurobiol 40 1999 185 201 (Pubitemid 29343303)
-
(1999)
Journal of Neurobiology
, vol.40
, Issue.2
, pp. 185-201
-
-
Martin, L.J.1
Kaiser, A.2
Price, A.C.3
-
137
-
-
0031856524
-
Apoptosis of retrogradely degenerating neurons occurs in association with the accumulation of perikaryal mitochondria and oxidative damage to the nucleus
-
N.A. Al-Abdulla, and L.J. Martin Apoptosis of retrogradely degenerating neurons occurs in association with accumulation of perikaryal mitochondria and oxidative damage to the nucleus Am J Pathol 153 1998 447 456 (Pubitemid 28373656)
-
(1998)
American Journal of Pathology
, vol.153
, Issue.2
, pp. 447-456
-
-
Al-Abdulla, N.A.1
Martin, L.J.2
-
138
-
-
79959504861
-
An approach to experimental synaptic pathology using green fluorescent protein-transgenic mice and gene knockout mice: Excitotoxic vulnerability of interneurons and motoneurons is associated with mitochondrial accumulation and mediated by the mitochondrial permeability transition pore
-
L.J. Martin An approach to experimental synaptic pathology using green fluorescent protein-transgenic mice and gene knockout mice: excitotoxic vulnerability of interneurons and motoneurons is associated with mitochondrial accumulation and mediated by the mitochondrial permeability transition pore Toxicol Pathol 39 1 2011 220 233
-
(2011)
Toxicol Pathol
, vol.39
, Issue.1
, pp. 220-233
-
-
Martin, L.J.1
-
139
-
-
0025283961
-
Developmental cell death: Morphological diversity and multiple mechanisms
-
P.G.H. Clarke Developmental cell death: morphological diversity and multiple mechanisms Anat Embryol 181 1990 195 213 (Pubitemid 20153523)
-
(1990)
Anatomy and Embryology
, vol.181
, Issue.3
, pp. 195-213
-
-
Clarke, P.G.H.1
-
140
-
-
0015880897
-
The morphology of various types of cell death in prenatal tissues
-
J.U. Schweichel, and H.J. Merker The morphology of various types of cell death in prenatal tissues Teratology 7 1973 253 266
-
(1973)
Teratology
, vol.7
, pp. 253-266
-
-
Schweichel, J.U.1
Merker, H.J.2
-
141
-
-
0032870475
-
Autophagy is activated by apoptotic signalling in sympathetic neurons: An alternative mechanism of death execution
-
DOI 10.1006/mcne.1999.0780
-
L.Z. Xue, G.C. Fletcher, and A.M. Tolkovsky Autophagy is activated by apoptotic signaling in sympathetic neurons: an alternative mechanism of death execution Mol Cell Neurosci 14 1999 180 198 (Pubitemid 29449222)
-
(1999)
Molecular and Cellular Neurosciences
, vol.14
, Issue.3
, pp. 180-198
-
-
Xue, L.1
Fletcher, G.C.2
Tolkovsky, A.M.3
-
142
-
-
0037194894
-
A novel protein complex linking the δ2 glutamate receptor and autophagy: Implications for neurodegeneration in Lurcher mice
-
Z. Yue, A. Horton, M. Bravin, P.L. DeJager, F. Selimi, and N. Heintz A novel protein complex linking the δ2 glutamate receptor and autophagy: implications for neurodegeneration in Lurcher mice Neuron 35 2002 921 933
-
(2002)
Neuron
, vol.35
, pp. 921-933
-
-
Yue, Z.1
Horton, A.2
Bravin, M.3
Dejager, P.L.4
Selimi, F.5
Heintz, N.6
-
143
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
T. Hara, K. Nakamura, M. Matsui, A. Yamamoto, Y. Nakahara, and R. Suzuki-Migishima Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice Nature 44 2006 885 889
-
(2006)
Nature
, vol.44
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
-
144
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
M. Komatsu, S. Waguri, T. Chiba, S. Murata, J. Iwata, and I. Tanida Loss of autophagy in the central nervous system causes neurodegeneration in mice Nature 44 2006 880 884
-
(2006)
Nature
, vol.44
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
-
145
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
D. Nakendra, A. Tanaka, D.-F. Suen, and R.J. Youle Parkin is recruited selectively to impaired mitochondria and promotes their autophagy J Cell Biol 183 2008 795 803
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Nakendra, D.1
Tanaka, A.2
Suen, D.-F.3
Youle, R.J.4
-
146
-
-
0141884305
-
Diversity in the mechanisms of neuronal cell death
-
DOI 10.1016/S0896-6273(03)00601-9
-
J. Yuan, M. Lipinski, and A. Degterev Diversity in the mechanisms of neuronal cell death Neuron 40 2003 401 413 (Pubitemid 37244104)
-
(2003)
Neuron
, vol.40
, Issue.2
, pp. 401-413
-
-
Yuan, J.1
Lipinski, M.2
Degterev, A.3
-
148
-
-
0034948738
-
The autophagosomal-lysosomal compartment in programmed cell death
-
DOI 10.1038/sj.cdd.4400852
-
W. Bursch The autophagosomal-lysosomal compartment in programmed cell death Cell Death Differ 8 2001 569 581 (Pubitemid 32590778)
-
(2001)
Cell Death and Differentiation
, vol.8
, Issue.6
, pp. 569-581
-
-
Bursch, W.1
-
149
-
-
0037193474
-
DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
-
DOI 10.1083/jcb.200109094
-
B. Inbal, S. Bialik, I. Sabanay, G. Shani, and A. Kimchi DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death J Cell Biol 157 2002 455 468 (Pubitemid 34839809)
-
(2002)
Journal of Cell Biology
, vol.157
, Issue.3
, pp. 455-468
-
-
Inbal, B.1
Bialik, S.2
Sabanay, I.3
Shani, G.4
Kimchi, A.5
-
150
-
-
0001488499
-
Protection against fatal sindbis virus encephalitis by Beclin, a novel Bcl-2-interacting protein
-
X.H. Liange, L.K. Kleeman, H.H. Jiang, G. Gordon, J.E. Goldman, and G. Berry Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein J Virol 72 1998 8586 8596 (Pubitemid 28471796)
-
(1998)
Journal of Virology
, vol.72
, Issue.11
, pp. 8586-8596
-
-
Liang, X.H.1
Kleeman, L.K.2
Jiang, H.H.3
Gordon, G.4
Goldman, J.E.5
Berry, G.6
Herman, B.7
Levine, B.8
-
152
-
-
5444236916
-
Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1
-
DOI 10.1242/jcs.01299
-
A. Varadi, L.I. Johnson-Cadwell, V. Cirulli, Y. Yoon, V.J. Allan, and G.A. Rutter Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1 J Cell Sci 117 2004 4389 4400 (Pubitemid 39360066)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.19
, pp. 4389-4400
-
-
Varadi, A.1
Johnson-Cadwell, L.I.2
Cirulli, V.3
Yoon, Y.4
Allan, V.J.5
Rutter, G.A.6
-
153
-
-
0037164813
-
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
-
DOI 10.1083/jcb.200209124
-
M. Karbowski, Y.-L. Lee, B. Gaume, S.-Y. Jeong, S. Frank, and A. Nechushtan Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis J Cell Biol 159 2002 931 938 (Pubitemid 36055748)
-
(2002)
Journal of Cell Biology
, vol.159
, Issue.6
, pp. 931-938
-
-
Karbowski, M.1
Lee, Y.-J.2
Gaume, B.3
Jeong, S.-Y.4
Frank, S.5
Nechushtan, A.6
Santel, A.7
Fuller, M.8
Smith, C.L.9
Youle, R.J.10
-
154
-
-
0029803242
-
In situ localization of mitochondrial DNA replication in intact mammalian cells
-
A.F. Davis, and D.A. Clayton In situ localization of mitochondrial DNA replication in intact mammalian cells J Cell Biol 135 1996 883 893 (Pubitemid 26403766)
-
(1996)
Journal of Cell Biology
, vol.135
, Issue.4
, pp. 883-893
-
-
Davis, A.F.1
Clayton, D.A.2
-
155
-
-
0347579845
-
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
-
DOI 10.1126/science.1079368
-
E. Nisoli, E. Clementi, C. Paolucci, V. Cozzi, C. Tonello, and C. Sciorati Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide Science 299 2003 896 899 (Pubitemid 36182449)
-
(2003)
Science
, vol.299
, Issue.5608
, pp. 896-899
-
-
Nisoli, E.1
Clementi, E.2
Paolucci, C.3
Cozzi, V.4
Tonello, C.5
Sciorati, C.6
Bracale, R.7
Valerio, A.8
Francolini, M.9
Moncada, S.10
Carruba, M.O.11
-
156
-
-
0027389516
-
Education and the prevalence of dementia and Alzheimer's disease
-
R. Katzman Education and the prevalence of dementia and Alzheimer's disease Neurology 43 1993 13 20 (Pubitemid 23035350)
-
(1993)
Neurology
, vol.43
, Issue.1
, pp. 13-20
-
-
Katzman, R.1
-
157
-
-
0024317904
-
Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported
-
D.A. Evans, H.H. Funkenstein, M.S. Albert, P.A. Scherr, N.R. Cook, and M.J. Chown Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported JAMA 262 1989 2551 2556
-
(1989)
JAMA
, vol.262
, pp. 2551-2556
-
-
Evans, D.A.1
Funkenstein, H.H.2
Albert, M.S.3
Scherr, P.A.4
Cook, N.R.5
Chown, M.J.6
-
158
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
-
G. McKhann, D. Drachman, M. Folstein, R. Katzman, D. Price, and E.M. Stadlan Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services task force on Alzheimer's disease Neurology 34 1984 939 944 (Pubitemid 14076461)
-
(1984)
Neurology
, vol.34
, Issue.7
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
-
161
-
-
0026075602
-
Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene
-
M.-C. Chartier-Harlin, F. Crawford, H. Houlden, A. Warren, D. Hughes, and L. Fidani Early-onset Alzheimer's disease caused by mutations at codon 717 of
-
(1991)
Nature
, vol.353
, Issue.6347
, pp. 844-846
-
-
Chartier-Harlin, M.-C.1
Crawford, F.2
Houlden, H.3
Warren, A.4
Hughes, D.5
Fidani, L.6
Goate, A.7
Rossor, M.8
Roques, P.9
Hardy, J.10
Mullan, M.11
-
163
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
A. Goate, M.C. Chartier-Harlin, M. Mullan, J. Brown, F. Crawford, and L. Fidani Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease Nature 349 1991 704 706 (Pubitemid 21912142)
-
(1991)
Nature
, vol.349
, Issue.6311
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fldani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
164
-
-
0025754007
-
Mis-sense mutation Val->Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease
-
S. Naruse, S. Igarashi, H. Kobayashi, K. Aoki, T. Inuzuka, and K. Kaneko Mis-sense mutation Val->Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease Lancet 337 1991 978 979
-
(1991)
Lancet
, vol.337
, pp. 978-979
-
-
Naruse, S.1
Igarashi, S.2
Kobayashi, H.3
Aoki, K.4
Inuzuka, T.5
Kaneko, K.6
-
165
-
-
0028812820
-
Mutations of the presenilin 1 gene in families with early-onset Alzheimer's disease
-
D. Campion, J.M. Flaman, A. Brice, D. Hannequin, B. Dubois, and C. Martin Mutations of the presenilin 1 gene in families with early-onset Alzheimer's disease Hum Mol Genet 4 1995 2373 2377
-
(1995)
Hum Mol Genet
, vol.4
, pp. 2373-2377
-
-
Campion, D.1
Flaman, J.M.2
Brice, A.3
Hannequin, D.4
Dubois, B.5
Martin, C.6
-
166
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
R. Sherrington, E.I. Rogaev, Y. Liang, E.A. Rogaeva, G. Levesque, and M. Ikeda Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease Nature 375 1995 754 760
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
-
167
-
-
0037444082
-
Dementia comes of age in the developing world
-
DOI 10.1016/S0140-6736(03)12783-3
-
R.N. Kalaria Dementia comes of age in the developing world Lancet 361 2003 888 889 (Pubitemid 36332101)
-
(2003)
Lancet
, vol.361
, Issue.9361
, pp. 888-889
-
-
Kalaria, R.N.1
-
168
-
-
0030005627
-
Apolipoprotein E alleles as risk factors in Alzheimer's disease
-
DOI 10.1146/annurev.med.47.1.387
-
A.D. Roses Apolipoprotein E alleles as risk factors in Alzheimer's disease Annu Rev Med 47 1996 387 400 (Pubitemid 26138899)
-
(1996)
Annual Review of Medicine
, vol.47
, pp. 387-400
-
-
Roses, A.D.1
-
169
-
-
0020072221
-
Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain
-
P.J. Whitehouse, D.L. Price, R.G. Struble, A.W. Clark, J.T. Coyle, and M.R. DeLong Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain Science 215 1982 1237 1239 (Pubitemid 12106486)
-
(1982)
Science
, vol.215
, Issue.4537
, pp. 1237-1239
-
-
Whitehouse, P.J.1
Price, D.L.2
Struble, R.G.3
-
170
-
-
0029979798
-
Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease
-
T. Gomez-Isla, J.L. Price, D.W. McKeel Jr., J.C. Morris, J.H. Growdon, and B.T. Hyman Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease J Neurosci 16 1996 4491 4500 (Pubitemid 26243044)
-
(1996)
Journal of Neuroscience
, vol.16
, Issue.14
, pp. 4491-4500
-
-
Gomez-Isla, T.1
Price, J.L.2
McKeel Jr., D.W.3
Morris, J.C.4
Growdon, J.H.5
Hyman, B.T.6
-
171
-
-
0032424143
-
Cognitive decline strongly correlates with cortical atrophy in Alzheimer's dementia
-
DOI 10.1016/S0197-4580(98)00080-3, PII S0197458098000803
-
P.R. Mouton, L.J. Martin, M.E. Calhoun, G. Dal Forno, and D.L. Price Cognitive decline strongly correlates with cortical atrophy in Alzheimer's disease Neurobiol Aging 19 1998 371 377 (Pubitemid 29065485)
-
(1998)
Neurobiology of Aging
, vol.19
, Issue.5
, pp. 371-377
-
-
Mouton, P.R.1
Martin, L.J.2
Calhoun, M.E.3
Dal Forno, G.4
Price, D.L.5
-
173
-
-
0141505027
-
Neocortical glial cell numbers in Alzheimer's disease: A stereological study
-
DOI 10.1159/000072805
-
D.P. Pelvig, H. Pakkenberg, L. Regeur, S. Oster, and B. Pakkenberg Neocortical glial cell numbers in Alzheimer's disease. A stereological study Dement Geriatr Cogn Disord 16 2003 212 219 (Pubitemid 37188116)
-
(2003)
Dementia and Geriatric Cognitive Disorders
, vol.16
, Issue.4
, pp. 212-219
-
-
Pelvig, D.P.1
Pakkenberg, H.2
Regeur, L.3
Oster, S.4
Pakkenberg, B.5
-
174
-
-
14444275560
-
Neuropathology of preclinical and clinical late-onset Alzheimer's disease
-
DOI 10.1002/ana.410430519
-
J.C. Troncoso, A.M. Cataldo, R.A. Nixon, J.L. Barnett, M.K. Lee, and F. Checler Neuropathology of preclinical and clinical late-onset Alzheimer's disease Ann Neurol 43 1998 673 676 (Pubitemid 28225562)
-
(1998)
Annals of Neurology
, vol.43
, Issue.5
, pp. 673-676
-
-
Troncoso, J.C.1
Cataldo, A.M.2
Nixon, R.A.3
Barnett, J.L.4
Lee, M.K.5
Checler, F.6
Fowler, D.R.7
Smialek, J.E.8
Crain, B.9
Martin, L.J.10
Kawas, C.H.11
-
176
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
J. Hardy, and D.J. Selkoe The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science 297 2002 353 356 (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
177
-
-
0035188745
-
N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease
-
PII S0022510X00004676
-
C.-I. Sze, H. Bi, B.K. Kleinschmidt-DeMasters, C.M. Filley, and L.J. Martin N-Methyl-D-aspartate receptor subunit proteins and their phosphorylation status are altered selectively in Alzheimer's disease J Neurol Sci 182 2001 151 159 (Pubitemid 33786712)
-
(2001)
Journal of the Neurological Sciences
, vol.182
, Issue.2
, pp. 151-159
-
-
Sze, C.-I.1
Bi, H.2
Kleinschmidt-DeMasters, B.K.3
Filley, C.M.4
Martin, L.J.5
-
178
-
-
0036830627
-
NMDA receptor pathways as drug targets
-
DOI 10.1038/nn936
-
J.A. Kemp, and R.M. McKernan NMDA receptor pathways as drug targets Nat Neurosci 5 2002 1039 1042 (Pubitemid 35247194)
-
(2002)
Nature Neuroscience
, vol.5
, Issue.SUPPL.
, pp. 1039-1042
-
-
Kemp, J.A.1
McKernan, R.M.2
-
179
-
-
0026570528
-
β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
-
M.P. Mattson, B. Cheng, D. Davis, K. Bryant, I. Lieberburg, and R.E. Rydel β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity J Neurosci 12 1993 376 389
-
(1993)
J Neurosci
, vol.12
, pp. 376-389
-
-
Mattson, M.P.1
Cheng, B.2
Davis, D.3
Bryant, K.4
Lieberburg, I.5
Rydel, R.E.6
-
180
-
-
39149122810
-
Amyloid beta, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimer's disease
-
P.H. Reddy, and M.F. Beal Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease Trends Mol Med 14 2008 45 53
-
(2008)
Trends Mol Med
, vol.14
, pp. 45-53
-
-
Reddy, P.H.1
Beal, M.F.2
-
181
-
-
0025269152
-
Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity
-
S.T. DeKosky, and S.W. Scheff Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity Ann Neurol 27 1990 457 464 (Pubitemid 20149963)
-
(1990)
Annals of Neurology
, vol.27
, Issue.5
, pp. 457-464
-
-
DeKosky, S.T.1
Scheff, S.W.2
-
182
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
-
R.D. Terry, E. Masliah, D.P. Salmon, N. Butters, R. DeTeresa, and R. Hill Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment Ann Neurol 30 1991 572 580
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
Deteresa, R.5
Hill, R.6
-
183
-
-
0028113719
-
Synaptic pathology and glial responses to neuronal injury precede the formation of senile plaques and amyloid deposits in the aging cerebral cortex
-
L.J. Martin, C.A. Pardo, L.C. Cork, and D.L. Price Synaptic pathology and glial responses to neuronal injury precede the formation of senile plaques and amyloid deposits in the aging cerebral cortex Am J Pathol 145 1994 1358 1381 (Pubitemid 24378491)
-
(1994)
American Journal of Pathology
, vol.145
, Issue.6
, pp. 1358-1381
-
-
Martin, L.J.1
Pardo, C.A.2
Cork, L.C.3
Price, D.L.4
-
184
-
-
0030872413
-
Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer's disease
-
C.-I. Sze, J.C. Troncoso, C. Kawas, P. Mouton, D.L. Price, and L.J. Martin Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer's disease J Neuropathol Exp Neurol 56 1997 933 994
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 933-994
-
-
Sze, C.-I.1
Troncoso, J.C.2
Kawas, C.3
Mouton, P.4
Price, D.L.5
Martin, L.J.6
-
185
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
DOI 10.1126/science.1074069
-
D.J. Selkoe Alzheimer's disease is a synaptic failure Science 298 2002 789 791 (Pubitemid 35231524)
-
(2002)
Science
, vol.298
, Issue.5594
, pp. 789-791
-
-
Selkoe, D.J.1
-
186
-
-
0024472693
-
Neurotixicity of a fragment of the amyloid precursor associated with Alzheimer's disease
-
B.A. Yankner, L.R. Dawes, S. Fisher, L. Villa-Komaroff, M.L. Oster-Granite, and R.L. Neve Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease Science 245 1989 417 420 (Pubitemid 19203368)
-
(1989)
Science
, vol.245
, Issue.4916
, pp. 417-420
-
-
Yankner, B.A.1
Dawes, L.R.2
Fisher, S.3
Villa-Komaroff, L.4
Oster-Granite, M.L.5
Neve, R.L.6
-
187
-
-
0028945660
-
Evidence that Abeta 42 is the real culprit in Alzheimer's disease
-
S.G. Younkin Evidence that Abeta 42 is the real culprit in Alzheimer's disease Ann Neurol 37 1995 287 288
-
(1995)
Ann Neurol
, vol.37
, pp. 287-288
-
-
Younkin, S.G.1
-
188
-
-
0037111833
-
Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease
-
T. Fath, J. Eidenmuller, and R. Brandt Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease J Neurosci 22 2002 9733 9741 (Pubitemid 35332856)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.22
, pp. 9733-9741
-
-
Fath, T.1
Eidenmuller, J.2
Brandt, R.3
-
189
-
-
0037197836
-
Tau is essential to β-amyloid-induced neurotoxicity
-
M. Rapoport, H.N. Dawson, L.I. Binder, M.P. Vitek, and A. Ferreira Tau is essential to β-amyloid-induced neurotoxicity Proc Natl Acad Sci USA 99 2002 6364 6369
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6364-6369
-
-
Rapoport, M.1
Dawson, H.N.2
Binder, L.I.3
Vitek, M.P.4
Ferreira, A.5
-
190
-
-
0037437192
-
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
-
DOI 10.1083/jcb.200207030
-
H.K. Anandatheerthavarada, G. Biswas, M.A. Robin, and N.G. Avadhani Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells J Cell Biol 161 2003 41 54 (Pubitemid 36459078)
-
(2003)
Journal of Cell Biology
, vol.161
, Issue.1
, pp. 41-54
-
-
Anandatheerthavarada, H.K.1
Biswas, G.2
Robin, M.-A.3
Avadhani, N.G.4
-
191
-
-
33748283747
-
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
-
DOI 10.1523/JNEUROSCI.1469-06.2006
-
L. Devi, B.M. Prabhu, D.F. Galati, N.G. Avadhani, and H.K. Anandatheerthavarada Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction J Neurosci 26 2006 9057 9068 (Pubitemid 44319397)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.35
, pp. 9057-9068
-
-
Devi, L.1
Prabhu, B.M.2
Galati, D.F.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
192
-
-
33646152108
-
Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: Implications for free radical generation and oxidative damage in disease progression
-
M. Manczak, T.S. Anekonda, E. Henson, B.S. Park, J. Quinn, and P.H. Reddy Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression Hum Mol Genet 15 2006 1437 1449
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
Park, B.S.4
Quinn, J.5
Reddy, P.H.6
-
193
-
-
11144353586
-
ABAD Directly Links Aβ to Mitochondrial Toxicity in Alzheimer's Disease
-
DOI 10.1126/science.1091230
-
J.W. Lustbader, M. Cirilli, C. Lin, H.W. Xu, K. Takuma, and N. Wang ABAD directly links Aβ to mitochondrial toxicity in Alzheimer's disease Science 304 2004 448 452 (Pubitemid 38495942)
-
(2004)
Science
, vol.304
, Issue.5669
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
Trinchese, F.11
Liu, S.12
Gunn-Moore, F.13
Lue, L.-F.14
Walker, D.G.15
Kappasamy, P.16
Zewier, Z.L.17
Arancio, O.18
Stern, D.19
Yan, S.S.D.20
Wu, H.21
more..
-
194
-
-
53549129483
-
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
-
H. Du, L. Guo, F. Fang, D. Chen, A.A. Sosunov, and G.M. McKhann Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease Nat Med 14 2008 1097 1105
-
(2008)
Nat Med
, vol.14
, pp. 1097-1105
-
-
Du, H.1
Guo, L.2
Fang, F.3
Chen, D.4
Sosunov, A.A.5
McKhann, G.M.6
-
195
-
-
36949016215
-
Alzheimer disease models and human neuropathology: Similarities and differences
-
DOI 10.1007/s00401-007-0312-8
-
C. Duyckaerts, M.C. Potier, and B. Delatour Alzheimer disease models and human neuropathology: similarities and differences Acta Neuropathol 115 2008 5 38 (Pubitemid 50005258)
-
(2008)
Acta Neuropathologica
, vol.115
, Issue.1
, pp. 5-38
-
-
Duyckaerts, C.1
Potier, M.-C.2
Delatour, B.3
-
196
-
-
0037675042
-
Incidence of Parkinson's disease: Variations by age, gender and race ethnicity
-
S.K. Van Den Eeden, C.M. Tanner, A.L. Bernstein, R.D. Fross, A. Leimpeter, and D.A. Bloch Incidence of Parkinson's disease: variations by age, gender and race ethnicity Am J Epidemol 157 2003 1015 1022
-
(2003)
Am J Epidemol
, vol.157
, pp. 1015-1022
-
-
Van Den Eeden, S.K.1
Tanner, C.M.2
Bernstein, A.L.3
Fross, R.D.4
Leimpeter, A.5
Bloch, D.A.6
-
197
-
-
41149163183
-
Parkinson's disease: Clinical features and diagnosis
-
DOI 10.1136/jnnp.2007.131045
-
J. Jankovic Parkinson's disease: clinical features and diagnosis J Neurol Neurosurg Psychiatry 79 2008 368 376 (Pubitemid 351441488)
-
(2008)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.79
, Issue.4
, pp. 368-376
-
-
Jankovic, J.1
-
198
-
-
0000244524
-
Disorders of movement and system degeneration
-
D.I. Graham, P.L. Lantos, Arnold London
-
J. Lowe, G. Lennox, and P.N. Leigh Disorders of movement and system degeneration D.I. Graham, P.L. Lantos, Greenfields neuropathology 1997 Arnold London 281 366
-
(1997)
Greenfields Neuropathology
, pp. 281-366
-
-
Lowe, J.1
Lennox, G.2
Leigh, P.N.3
-
199
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
DOI 10.1016/S0197-4580(02)00065-9, PII S0197458002000659
-
H. Braak, K. Del Tredici, U. Rüb, R.A.I. de Vos, E.N.H. Jansen Steur, and E. Braak Staging of brain pathology related to sporadic Parkinson's disease Neurobiol Aging 24 2003 197 211 (Pubitemid 36007810)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.2
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
De Vos, R.A.I.4
Jansen Steur, E.N.H.5
Braak, E.6
-
200
-
-
42149134004
-
Neurodegenerative disorders of the human brain and spinal cord
-
V.S. Ramachandran, Elsevier Science Amsterdam
-
L.J. Martin Neurodegenerative disorders of the human brain and spinal cord V.S. Ramachandran, Encyclopedia of the human brain Vol. 3 2002 Elsevier Science Amsterdam 441 463
-
(2002)
Encyclopedia of the Human Brain
, vol.3
, pp. 441-463
-
-
Martin, L.J.1
-
201
-
-
0035409575
-
Alpha-synuclein and neurodegenerative diseases
-
DOI 10.1038/35081564
-
M. Goedert Alpha-synuclein and neurodegenerative diseases Nat Rev Neurosci 2 2001 492 501 (Pubitemid 33676584)
-
(2001)
Nature Reviews Neuroscience
, vol.2
, Issue.7
, pp. 492-501
-
-
Goedert, M.1
-
202
-
-
33746803713
-
Pesticide exposure and risk for Parkinson's disease
-
DOI 10.1002/ana.20904
-
A. Ascherio, H. Chen, M.G. Weisskopf, E. O'Reilly, M.L. McCullough, and E.E. Calle Pesticide exposure and risk for Parkinson's disease Ann Neurol 60 2006 197 203 (Pubitemid 44182394)
-
(2006)
Annals of Neurology
, vol.60
, Issue.2
, pp. 197-203
-
-
Ascherio, A.1
Chen, H.2
Weisskopf, M.G.3
O'Reilly, E.4
McCullough, M.L.5
Calle, E.E.6
Schwarzschild, M.A.7
Thun, M.J.8
-
203
-
-
33744982893
-
Etiology of Parkinson's disease
-
A.H.V. Schapira Etiology of Parkinson's disease Neurology 66 Suppl. 4 2006 S10 S23
-
(2006)
Neurology
, vol.66
, Issue.SUPPL. 4
-
-
Schapira, A.H.V.1
-
204
-
-
0041926269
-
Disease model: Parkinson's disease
-
DOI 10.1016/S1471-4914(03)00117-5
-
S. Shimohama, H. Swada, Y. Kitamura, and T. Taniguchi Disease model: Parkinson's disease Trends Mol Med 9 2003 360 365 (Pubitemid 37040032)
-
(2003)
Trends in Molecular Medicine
, vol.9
, Issue.8
, pp. 360-365
-
-
Shimohama, S.1
Sawada, H.2
Kitamura, Y.3
Taniguchi, T.4
-
205
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
DOI 10.1126/science.276.5321.2045
-
M.H. Polymeropoulos, C. Lavedan, E. Leroy, S.E. Ide, A. Dehejia, and A. Dutra Mutation in the α-synuclein gene identified in families with Parkinson's disease Science 276 1997 2045 2047 (Pubitemid 27443610)
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
206
-
-
0242300619
-
α-Synuclein Locus Triplication Causes Parkinson's Disease
-
DOI 10.1126/science.1090278
-
A.B. Singleton, M. Farrer, J. Johnson, A. Singleton, S. Hague, and J. Kachergus Alpha-synuclein locus triplication causes Parkinson's disease Science 302 2003 841 (Pubitemid 37339619)
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
207
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
E. Leroy, R. Boyer, G. Auburger, B. Leube, G. Ulm, and E. Mezey The ubiquitin pathway in Parkinson's disease Nature 395 1998 451 452
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
Mezey, E.6
-
208
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
DOI 10.1126/science.1077209
-
V. Bonifati, P. Rizzu, M.J. van Baren, O. Schaap, G.J. Breedveld, and E. Krieger Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism Science 299 2003 256 259 (Pubitemid 36131051)
-
(2003)
Science
, vol.299
, Issue.5604
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.J.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
Van Dongen, J.W.11
Vanacore, N.12
Van Swieten, J.C.13
Brice, A.14
Meco, G.15
Van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
209
-
-
4444237208
-
Novel PINK1 mutations in early-onset parkinsonism
-
DOI 10.1002/ana.20251
-
Y. Hatano, Y. Li, K. Sato, S. Asakawa, Y. Yamamura, and H. Tomiyama Novel PINK1 mutations in early-onset parkinsonism Ann Neurol 56 2004 424 427 (Pubitemid 39166562)
-
(2004)
Annals of Neurology
, vol.56
, Issue.3
, pp. 424-427
-
-
Hatano, Y.1
Li, Y.2
Sato, K.3
Asakawa, S.4
Yamamura, Y.5
Tomiyama, H.6
Yoshino, H.7
Asahina, M.8
Kobayashi, S.9
Hassin-Baer, S.10
Lu, C.-S.11
Ng, A.R.12
Rosales, R.L.13
Shimizu, N.14
Toda, T.15
Mizuno, Y.16
Hattori, N.17
-
210
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
DOI 10.1038/33416
-
T. Kitada, S. Asakawa, N. Hattori, H. Matsumine, Y. Yamamura, and S. Minoshima Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism Nature 392 1998 605 608 (Pubitemid 28207717)
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
211
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
DOI 10.1126/science.1096284
-
E.M. Valente, P.M. Abou-Sleiman, V. Caputo, M.M. Muqit, K. Harvey, and A. Gispert Hereditary early-onset Parkinson's disease caused by mutations in PINK1 Science 304 2004 1158 1160 (Pubitemid 38661852)
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.K.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
212
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
-
DOI 10.1016/j.neuron.2004.10.023, PII S0896627304006890
-
C. Paisán-Ruíz, S. Jain, E. Whitney Evans, W.P. Gilks, J. Simón, and M. van der Brug Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease Neuron 44 2004 595 600 (Pubitemid 39531224)
-
(2004)
Neuron
, vol.44
, Issue.4
, pp. 595-600
-
-
Paisan-Ruiz, C.1
Jain, S.2
Evans, E.W.3
Gilks, W.P.4
Simon, J.5
Van Der Brug, M.6
De Munain, A.L.7
Aparicio, S.8
Gil, A.M.9
Khan, N.10
Johnson, J.11
Martinez, J.R.12
Nicholl, D.13
Carrera, I.M.14
Pena, A.S.15
De Silva, R.16
Lees, A.17
Marti-Masso, J.F.18
Perez-Tur, J.19
Wood, N.W.20
Singleton, A.B.21
more..
-
213
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
DOI 10.1016/j.neuron.2004.11.005, PII S0896627304007202
-
A. Zimprich, S. Biskup, P. Leitner, P. Lichtner, M. Farrer, and S. Lincoln Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology Neuron 44 2004 601 607 (Pubitemid 39531225)
-
(2004)
Neuron
, vol.44
, Issue.4
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
Lichtner, P.4
Farrer, M.5
Lincoln, S.6
Kachergus, J.7
Hulihan, M.8
Uitti, R.J.9
Calne, D.B.10
Stoessl, A.J.11
Pfeiffer, R.F.12
Patenge, N.13
Carbajal, I.C.14
Vieregge, P.15
Asmus, F.16
Muller-Myhsok, B.17
Dickson, D.W.18
Meitinger, T.19
Strom, T.M.20
Wszolek, Z.K.21
Gasser, T.22
more..
-
214
-
-
33749133430
-
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase
-
DOI 10.1038/ng1884, PII NG1884
-
A. Ramirez, A. Heimbach, J. Grundemann, B. Stiller, D. Hampshire, and L.P. Cid Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase Nat Genet 38 2006 1184 1191 (Pubitemid 44470365)
-
(2006)
Nature Genetics
, vol.38
, Issue.10
, pp. 1184-1191
-
-
Ramirez, A.1
Heimbach, A.2
Grundemann, J.3
Stiller, B.4
Hampshire, D.5
Cid, L.P.6
Goebel, I.7
Mubaidin, A.F.8
Wriekat, A.-L.9
Roeper, J.10
Al-Din, A.11
Hillmer, A.M.12
Karsak, M.13
Liss, B.14
Woods, C.G.15
Behrens, M.I.16
Kubisch, C.17
-
215
-
-
0036127407
-
Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death
-
DOI 10.1002/neu.10037
-
C. Lesuisse, and L.J. Martin Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death J Neurobiol 51 2002 9 23 (Pubitemid 34242501)
-
(2002)
Journal of Neurobiology
, vol.51
, Issue.1
, pp. 9-23
-
-
Lesuisse, C.1
Martin, L.J.2
-
216
-
-
0023722437
-
Synuclein: A neuron-specific protein localized to the nucleus and presynaptic nerve terminals
-
L. Maroteaux, J.T. Campanelli, and R.H. Scheller Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminals J Neurosci 8 1998 2804 2815
-
(1998)
J Neurosci
, vol.8
, pp. 2804-2815
-
-
Maroteaux, L.1
Campanelli, J.T.2
Scheller, R.H.3
-
217
-
-
0034193399
-
Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
-
D.D. Murphy, S.M. Rueter, J.Q. Trojanowski, and V.M.Y. Lee Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons J Neurosci 20 2000 3214 3220 (Pubitemid 30263139)
-
(2000)
Journal of Neuroscience
, vol.20
, Issue.9
, pp. 3214-3220
-
-
Murphy, D.D.1
Rueter, S.M.2
Trojanowski, J.Q.3
Lee, V.M.-Y.4
-
218
-
-
6944227811
-
Double-knockout mice for α- and β-synucleins: Effect on synaptic functions
-
DOI 10.1073/pnas.0406283101
-
S. Chandra, F. Fornai, H.B. Kwon, U. Yazdani, D. Atasoy, and X. Liu Double knockout mice for α- and β-synucleins: effect on synaptic functions Proc Natl Acad Sci USA 101 2004 14966 14971 (Pubitemid 39410782)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.41
, pp. 14966-14971
-
-
Chandra, S.1
Fornai, F.2
Kwon, H.-B.3
Yazdani, U.4
Atasoy, D.5
Liu, X.6
Hammer, R.E.7
Battaglia, G.8
German, D.C.9
Castillo, P.E.10
Sudhof, T.C.11
-
219
-
-
34548726221
-
Role of α-synuclein in synaptic glutamate release
-
DOI 10.1016/j.nbd.2007.06.016, PII S0969996107001362
-
I. Gurevicine, K. Gurevicius, and H. Tanila Role of α-synuclein in synaptic glutamate release Neurobiol Dis 28 2007 83 89 (Pubitemid 47429976)
-
(2007)
Neurobiology of Disease
, vol.28
, Issue.1
, pp. 83-89
-
-
Gureviciene, I.1
Gurevicius, K.2
Tanila, H.3
-
220
-
-
34347387566
-
α-Synuclein involvement in hippocampal synaptic plasticity: Role of NO, cGMP, cGK and CaMKII
-
DOI 10.1111/j.1460-9568.2007.05569.x
-
S. Liu, M. Fa, I. Ninan, F. Trinchese, W. Dauer, and O. Aranico α-Synuclein involvement in hippocampal synaptic plasticity: role of NO, cGMP, cGK and CAMKII Eur J Neurosci 25 2007 3583 3596 (Pubitemid 47020438)
-
(2007)
European Journal of Neuroscience
, vol.25
, Issue.12
, pp. 3583-3596
-
-
Liu, S.1
Fa, M.2
Ninan, I.3
Trinchese, F.4
Dauer, W.5
Arancio, O.6
-
221
-
-
28044461467
-
Neural activity controls the synaptic accumulation of α-synuclein
-
DOI 10.1523/JNEUROSCI.2922-05.2005
-
D.L. Fortin, V.M. Nemani, S.M. Voglmaier, M.D. Anthony, T.A. Ryan, and R.H. Edwards Neural activity control the synaptic accumulation of α-synuclein J Neurosci 25 2005 10913 10921 (Pubitemid 41692621)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.47
, pp. 10913-10921
-
-
Fortin, D.L.1
Nemani, V.M.2
Voglmaier, S.M.3
Anthony, M.D.4
Ryan, T.A.5
Edwards, R.H.6
-
222
-
-
27544507306
-
α-Synuclein cooperates with CSPα in preventing neurodegeneration
-
DOI 10.1016/j.cell.2005.09.028, PII S0092867405010226
-
S. Chandra, G. Gallardo, R. Fernandez-Chacon, O.M. Schluter, and T.C. Sudholf α-Synuclein cooperates with CSPα in preventing neurodegeneration Cell 123 2005 383 396 (Pubitemid 41546670)
-
(2005)
Cell
, vol.123
, Issue.3
, pp. 383-396
-
-
Chandra, S.1
Gallardo, G.2
Fernandez-Chacon, R.3
Schluter, O.M.4
Sudhof, T.C.5
-
223
-
-
39749185957
-
A molecular pathway of neurodegeneration linking α-synuclein to ApoE and Aβ peptides
-
DOI 10.1038/nn2058, PII NN2058
-
G. Gallardo, O.M. Schluter, and T.C. Sudhof A molecular pathway of neurodegeneration linking α-synuclein to ApoE and Aβ peptides Nat Neurosci 11 2008 301 308 (Pubitemid 351311805)
-
(2008)
Nature Neuroscience
, vol.11
, Issue.3
, pp. 301-308
-
-
Gallardo, G.1
Schluter, O.M.2
Sudhof, T.C.3
-
224
-
-
0034712918
-
Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation
-
DOI 10.1073/pnas.97.9.4897
-
L.C. Serpell, J. Berriman, M. Jakes, M. Goedert, and R.A. Crowther Fiber diffraction of synthetic alpha synuclein filaments shows amyloid-like cross-beta conformation Proc Natl Acad Sci USA 97 2000 4897 4902 (Pubitemid 30238654)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.9
, pp. 4897-4902
-
-
Serpell, L.C.1
Berriman, J.2
Jakes, R.3
Goedert, M.4
Crowther, R.A.5
-
225
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
-
DOI 10.1073/pnas.97.2.571
-
K.A. Conway, S.J. Lee, J.C. Rochet, T.T. Ding, R.E. Williamson, and P.T. Lansbury Jr. Acceleration of oligomerization, not fibrilization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy Proc Natl Acad Sci USA 97 2000 571 576 (Pubitemid 30070350)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.2
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.-J.2
Rochet, J.-C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury Jr., P.T.6
-
226
-
-
0037551741
-
Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders
-
DOI 10.1146/annurev.neuro.26.010302.081142
-
B. Caughey, and P.T. Lansbury Protofibrils, pores, fibril, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders Annu Rev Neurosci 26 2003 267 298 (Pubitemid 37064935)
-
(2003)
Annual Review of Neuroscience
, vol.26
, pp. 267-298
-
-
Caughey, B.1
Lansbury Jr., P.T.2
-
227
-
-
0033890821
-
α-synuclein promotes mitochondrial deficit and oxidative stress
-
L.J. Hsu, Y. Sagara, A. Arroyo, E. Rockenstein, A. Sisk, and M. Mallory Alpha-synuclein promotes mitochondrial deficit and oxidative stress Am J Pathol 157 2000 401 410 (Pubitemid 30627559)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.2
, pp. 401-410
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
Rockenstein, E.4
Sisk, A.5
Mallory, M.6
Wong, J.7
Takenouchi, T.8
Hashimoto, M.9
Masliah, E.10
-
228
-
-
0037040491
-
Human α-Synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine
-
DOI 10.1016/S0304-3940(02)00016-2, PII S0304394002000162
-
E. Junn, and M.M. Mouradian Human α-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine Neurosci Lett 320 2002 146 150 (Pubitemid 34164436)
-
(2002)
Neuroscience Letters
, vol.320
, Issue.3
, pp. 146-150
-
-
Junn, E.1
Mouradian M.Maral2
-
229
-
-
0034326816
-
Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity
-
S.J. Tabrizi, M. Orth, J.M. Wilkinson, J.W. Taanman, T.T. Warner, and J.M. Cooper Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity Hum Mol Genet 9 2000 2683 2689
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2683-2689
-
-
Tabrizi, S.J.1
Orth, M.2
Wilkinson, J.M.3
Taanman, J.W.4
Warner, T.T.5
Cooper, J.M.6
-
230
-
-
0037118259
-
Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein
-
DOI 10.1016/S0896-6273(02)00682-7
-
B.I. Giasson, J.E. Duda, S.M. Quinn, B. Zhang, J.Q. Trojanowski, and W.M.-Y. Lee Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein Neuron 34 2002 521 533 (Pubitemid 34628750)
-
(2002)
Neuron
, vol.34
, Issue.4
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
231
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
-
B.I. Giasson, J.E. Duda, I.V.J. Murray, Q. Chen, J.M. Souza, and H.I. Hurtig Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions Science 290 2000 985 989
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.J.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
-
232
-
-
0038389681
-
Oxidative modification of alpha-synuclein
-
H. Ischiropoulos Oxidative modification of alpha-synuclein Annu NY Acad Sci 991 2003 93 100
-
(2003)
Annu NY Acad Sci
, vol.991
, pp. 93-100
-
-
Ischiropoulos, H.1
-
233
-
-
0024461942
-
The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase
-
K.D. Wilkinson, K.M. Lee, S. Deshpande, P. Duerken-Hughes, J.M. Boss, and J. Pohl The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl terminal hydrolase Science 246 1989 670 673 (Pubitemid 19283361)
-
(1989)
Science
, vol.246
, Issue.4930
, pp. 670-673
-
-
Wilkinson, K.D.1
Lee, K.2
Deshpande, S.3
Duerksen-Hughes, P.4
Boss, J.M.5
Pohl, J.6
-
235
-
-
0036775723
-
Genetics of Parkinson's disease and biochemical studies of implicated gene products: Commentary
-
DOI 10.1016/S0955-0674(02)00377-0
-
P.T. Lansbury Jr., and A. Brice Genetics of Parkinson's disease and biochemical studies of implicated gene products Curr Opin Cell Biol 14 2002 653 660 (Pubitemid 35247750)
-
(2002)
Current Opinion in Cell Biology
, vol.14
, Issue.5
, pp. 653-660
-
-
Lansbury Jr., P.T.1
Brice, A.2
-
236
-
-
0036316947
-
Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures
-
DOI 10.1046/j.1471-4159.2002.00821.x
-
K.S. McNaught, C. Mytilineou, R. Jnobaptiste, J. Yabut, P. Shahidharan, and P. Jennert Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures J Neurochem 81 2002 301 306 (Pubitemid 34809355)
-
(2002)
Journal of Neurochemistry
, vol.81
, Issue.2
, pp. 301-306
-
-
McNaught, K.St.P.1
Mytilin, C.2
JnoBaptiste, R.3
Yabut, J.4
Shashidharan, P.5
Jenner, P.6
Olanow, C.W.7
-
237
-
-
2942541204
-
How do Parkin mutations result in neurodegeneration?
-
DOI 10.1016/j.conb.2004.04.002, PII S0959438804000650
-
Y. Imai, and R. Takahashi How do Parkin mutations result in neurodegeneration? Curr Opin Neurobiol 14 2004 384 389 (Pubitemid 38759870)
-
(2004)
Current Opinion in Neurobiology
, vol.14
, Issue.3
, pp. 384-389
-
-
Imai, Y.1
Takahashi, R.2
-
238
-
-
0032575607
-
Point mutations (Thr240Arg and Ala311Stop) in the Parkin gene
-
DOI 10.1006/bbrc.1998.9134
-
N. Hattori, H. Matsumine, S. Asakawa, T. Kitada, H. Yoshino, and B. Elibol Point mutations (Thr240Arg and Gln311Stop) in the Parkin gene Biochem Biophys Res Commun 249 1998 754 758 (Pubitemid 28441911)
-
(1998)
Biochemical and Biophysical Research Communications
, vol.249
, Issue.3
, pp. 754-758
-
-
Hattori, N.1
Matsumine, H.2
Asakawa, S.3
Kitada, T.4
Yoshino, H.5
Elibol, B.6
Brookes, A.J.7
Yamamura, Y.8
Kobayashi, T.9
Wang, M.10
Yoritaka, A.11
Minoshima, S.12
Shimizu, N.13
Mizuno, Y.14
-
239
-
-
17644365438
-
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability
-
DOI 10.1073/pnas.0500617102
-
A. Beilina, M. Van Der Brug, R. Ahmad, S. Kesavapany, D.W. Miller, and G.A. Petsko Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability Proc Natl Acad Sci USA 102 2005 5703 5708 (Pubitemid 40559623)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.16
, pp. 5703-5708
-
-
Beilina, A.1
Van Der Brug, M.2
Ahmad, R.3
Kesavapany, S.4
Miller, D.W.5
Petsko, G.A.6
Cookson, M.R.7
-
240
-
-
27944444154
-
Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism
-
DOI 10.1093/hmg/ddi377
-
L. Silvestri, V. Caputo, E. Bellacchio, L. Atorino, B. Dallapiccola, and E.M. Valente Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism Hum Mol Genet 14 2005 3477 3492 (Pubitemid 41672130)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.22
, pp. 3477-3492
-
-
Silvestri, L.1
Caputo, V.2
Bellacchio, E.3
Atorino, L.4
Dallapiccola, B.5
Valente, E.M.6
Casari, G.7
-
241
-
-
0035958558
-
Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway
-
DOI 10.1038/sj.onc.1204608
-
M. Unoki, and Y. Nakamura Growth-suppressive effects of BPOZ and RGR2, two genes involved in the PTEN signaling pathway Oncogene 20 2001 4457 4465 (Pubitemid 32772428)
-
(2001)
Oncogene
, vol.20
, Issue.33
, pp. 4457-4465
-
-
Unoki, M.1
Nakamura, Y.2
-
242
-
-
33745917404
-
Distribution of PINK1 and LRRK2 in rat and mouse brain
-
DOI 10.1111/j.1471-4159.2006.03919.x
-
J.-M. Taymans, C. Van den Haute, and V. Baekelandt Distribution of PINK1 and LRRK2 in rat and mouse brain J Neurochem 98 2006 951 961 (Pubitemid 44051294)
-
(2006)
Journal of Neurochemistry
, vol.98
, Issue.3
, pp. 951-961
-
-
Taymans, J.-M.1
Van Den Haute, C.2
Baekelandt, V.3
-
243
-
-
64549112144
-
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking
-
A. Weihofen, K.J. Thomas, B.L. Ostazewski, M.R. Cooksen, and D.J. Selkoe Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking Biochemistry 48 2009 2045 2052
-
(2009)
Biochemistry
, vol.48
, pp. 2045-2052
-
-
Weihofen, A.1
Thomas, K.J.2
Ostazewski, B.L.3
Cooksen, M.R.4
Selkoe, D.J.5
-
244
-
-
27144469287
-
Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y
-
DOI 10.1016/j.bbrc.2005.09.178, PII S0006291X05022205
-
H. Deng, J. Jankovic, Y. Guo, W. Xie, and W. Le Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y Biochem Biophys Res Commun 337 2005 1133 1138 (Pubitemid 41505244)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.337
, Issue.4
, pp. 1133-1138
-
-
Deng, H.1
Jankovic, J.2
Guo, Y.3
Xie, W.4
Le, W.5
-
245
-
-
61349156769
-
Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux
-
R. Marongiu, B. Spencer, L. Crews, A. Adame, C. Patrick, and M. Trejo Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux J Neurochem 108 2009 1561 1574
-
(2009)
J Neurochem
, vol.108
, pp. 1561-1574
-
-
Marongiu, R.1
Spencer, B.2
Crews, L.3
Adame, A.4
Patrick, C.5
Trejo, M.6
-
246
-
-
0042130551
-
The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease
-
DOI 10.1073/pnas.1133288100
-
M.A. Wilson, J.L. Collins, Y. Hod, D. Ringe, and G.A. Petsko The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease Proc Natl Acad Sci USA 100 2003 9256 9261 (Pubitemid 37033916)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.16
, pp. 9256-9261
-
-
Wilson, M.A.1
Collins, J.L.2
Hod, Y.3
Ringe, D.4
Petsko, G.A.5
-
247
-
-
4444266341
-
Localization of DJ-1 mRNA in the mouse brain
-
DOI 10.1016/j.neulet.2004.06.002, PII S0304394004007244
-
H. Shang, D. Lang, B. Jean-Marc, and A. Kaelin-Lang Localization of DJ-1 mRNA in the mouse brain Neurosci Lett 367 2004 273 277 (Pubitemid 39185844)
-
(2004)
Neuroscience Letters
, vol.367
, Issue.3
, pp. 273-277
-
-
Shang, H.1
Lang, D.2
Jean-Marc, B.3
Kaelin-Lang, A.4
-
248
-
-
2942684871
-
The Parkinson's disease DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
DOI 10.1073/pnas.0402959101
-
R.M. Canet-Aviles, M.A. Wilson, D.W. Miller, R. Ahmad, C. McLendon, and S. Bandyopadhyay The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization Proc Natl Acad Sci USA 101 2004 9103 9108 (Pubitemid 38781618)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.24
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
Baptista, M.J.7
Ringe, D.8
Petsko, G.A.9
Cookson, M.R.10
-
249
-
-
0141704202
-
L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system
-
DOI 10.1074/jbc.M304272200
-
D.W. Miller, R. Ahmad, S. Hague, M.J. Baptista, R. Canet-Aviles, and C. McLendon L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system J Biol Chem 278 2003 36588 36595 (Pubitemid 37139990)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.38
, pp. 36588-36595
-
-
Miller, D.W.1
Ahmad, R.2
Hague, S.3
Baptista, M.J.4
Canet-Aviles, R.5
McLendon, C.6
Carter, D.M.7
Zhu, P.-P.8
Stadler, J.9
Chandran, J.10
Klinefelter, G.R.11
Blackstone, C.12
Cookson, M.R.13
-
250
-
-
2942700097
-
Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients
-
DOI 10.1016/j.bbrc.2004.05.187, PII S0006291X04012094
-
K. Takahashi-Niki, T. Niki, T. Taira, S.M. Iguchi-Ariga, and H. Ariga Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients Biochem Biophys Res Commun 320 2004 389 397 (Pubitemid 38798879)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.320
, Issue.2
, pp. 389-397
-
-
Takahashi-Niki, K.1
Niki, T.2
Taira, T.3
Iguchi-Ariga, S.M.M.4
Ariga, H.5
-
251
-
-
33645790701
-
LRRK2 expression linked to dopamine-innervated areas
-
D. Galter, M. Westerlund, A. Carmine, E. Lindqvist, O. Sydow, and L. Olson LRRK2 expression linked to dopamine-innervated areas Ann Neurol 59 2006 714 719
-
(2006)
Ann Neurol
, vol.59
, pp. 714-719
-
-
Galter, D.1
Westerlund, M.2
Carmine, A.3
Lindqvist, E.4
Sydow, O.5
Olson, L.6
-
252
-
-
33646146878
-
Anatomical localization of leucine-rich repeat kinase 2 in mouse brain
-
DOI 10.1016/j.neuroscience.2006.01.017, PII S0306452206001175
-
H. Melrose, S. Lincoln, G. Tyndall, D. Dickson, and M. Farrer Anatomical localization of leucine-rich repeat kinase 2 mouse brain Neuroscience 139 2006 791 794 (Pubitemid 44308089)
-
(2006)
Neuroscience
, vol.139
, Issue.3
, pp. 791-794
-
-
Melrose, H.1
Lincoln, S.2
Tyndall, G.3
Dickson, D.4
Farrer, M.5
-
253
-
-
34447294546
-
Apoptotic mechanisms in mutant LRRK2-mediated cell death
-
DOI 10.1093/hmg/ddm080
-
C. Iaccarino, C. Crosio, C. Vitale, G. Sanna, M.T. Carri, and P. Barone Apoptotic mechanisms in mutant LRRK2-mediated cell death Hum Mol Genet 16 2007 1319 1326 (Pubitemid 47055127)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.11
, pp. 1319-1326
-
-
Laccarino, C.1
Crosio, C.2
Vitale, C.3
Sanna, G.4
Carri, M.T.5
Barone, P.6
-
254
-
-
59649089328
-
The Parkinson's disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration
-
C.C.-Y. Ho, H.J. Rideout, E. Ribe, C.M. Troy, and W.T. Dauer The Parkinson's disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration J Neurosci 29 2009 1011 1016
-
(2009)
J Neurosci
, vol.29
, pp. 1011-1016
-
-
Ho, C.C.-Y.1
Rideout, H.J.2
Ribe, E.3
Troy, C.M.4
Dauer, W.T.5
-
255
-
-
0141891953
-
Parkin-deficient Mice Exhibit Nigrostriatal Deficits but not Loss of Dopaminergic Neurons
-
DOI 10.1074/jbc.M308947200
-
M.S. Goldberg, S.M. Fleming, J.J. Palacino, C. Capedam, H.A. Lam, and A. Bhatnagar Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons J Biol Chem 278 2003 43628 43635 (Pubitemid 37345989)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.44
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
Cepeda, C.4
Lam, H.A.5
Bhatnagar, A.6
Meloni, E.G.7
Wu, N.8
Ackerson, L.C.9
Klapstein, G.J.10
Gajendiran, M.11
Roth, B.L.12
Chesselet, M.-F.13
Maidment, N.T.14
Levine, M.S.15
Shen, J.16
-
257
-
-
2442481789
-
Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice
-
DOI 10.1074/jbc.M401135200
-
J.J. Palacino, D. Sagi, M.S. Goldberg, S. Krauss, C. Motz, and M. Wacker Mitochondrial dysfunction and oxidative damage in parkin-deficient mice J Biol Chem 279 2004 18614 18622 (Pubitemid 38623283)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.18
, pp. 18614-18622
-
-
Palacino, J.J.1
Sagi, D.2
Goldberg, M.S.3
Krauss, S.4
Motz, C.5
Wacker, M.6
Klose, J.7
Shen, J.8
-
258
-
-
20444367300
-
Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice
-
DOI 10.1074/jbc.M413955200
-
L. Chen, B. Cagniard, T. Mathews, S. Jones, H.C. Koh, and Y. Ding Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice J Biol Chem 280 2005 21418 21426 (Pubitemid 40805706)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.22
, pp. 21418-21426
-
-
Chen, L.1
Cagniard, B.2
Mathews, T.3
Jones, S.4
Koh, H.C.5
Ding, Y.6
Carvey, P.M.7
Ling, Z.8
Kang, U.J.9
Zhuang, X.10
-
259
-
-
13844253723
-
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial parkinsonism-linked gene DJ-1
-
DOI 10.1016/j.neuron.2005.01.041
-
M.S. Goldberg, A. Pisani, M. Haburcak, T.A. Vortherms, Y. Kitada, and C. Costa Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial parkinsonism-linked gene DJ-1 Neuron 45 2005 489 496 (Pubitemid 40249861)
-
(2005)
Neuron
, vol.45
, Issue.4
, pp. 489-496
-
-
Goldberg, M.S.1
Pisani, A.2
Haburcak, M.3
Vortherms, T.A.4
Kitada, T.5
Costa, C.6
Tong, Y.7
Martella, G.8
Tscherter, A.9
Martins, A.10
Bernardi, G.11
Roth, B.L.12
Pothos, E.N.13
Calabresi, P.14
Shen, J.15
-
260
-
-
60849106352
-
Bacterial artificial chromosome transgenic mice expressing a truncated mutant Parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant α-synuclein
-
X.-H. Lu, S.M. Fleming, B. Meurers, L.C. Ackerson, F. Mortazavi, and V. Lo Bacterial artificial chromosome transgenic mice expressing a truncated mutant Parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant α-synuclein J Neurosci 29 2009 1962 1976
-
(2009)
J Neurosci
, vol.29
, pp. 1962-1976
-
-
Lu, X.-H.1
Fleming, S.M.2
Meurers, B.3
Ackerson, L.C.4
Mortazavi, F.5
Lo, V.6
-
261
-
-
10744221260
-
Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation
-
DOI 10.1016/S1044-7431(03)00198-2
-
S. Gispert, D. Del Turco, L. Garrett, A. Chen, D.J. Bernard, and J. Hamm-Clement Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence or aggregate formation Mol Cell Neurosci 24 2003 419 429 (Pubitemid 37311305)
-
(2003)
Molecular and Cellular Neuroscience
, vol.24
, Issue.2
, pp. 419-429
-
-
Gispert, S.1
Del Turco, D.2
Garrett, L.3
Chen, A.4
Bernard, D.J.5
Hamm-Clement, J.6
Korf, H.-W.7
Deller, T.8
Braak, H.9
Auburger, G.10
Nussbaum, R.L.11
-
262
-
-
0034280435
-
Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain
-
P.J. Kahle, M. Neumann, L. Ozmen, V. Muller, H. Jacobsen, and A. Schindzielorz Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain J Neurosci 20 2000 6365 6373
-
(2000)
J Neurosci
, vol.20
, pp. 6365-6373
-
-
Kahle, P.J.1
Neumann, M.2
Ozmen, L.3
Muller, V.4
Jacobsen, H.5
Schindzielorz, A.6
-
263
-
-
0037173006
-
Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice
-
DOI 10.1073/pnas.132197599
-
M.K. Lee, W. Stirling, Y. Xu, X. Xu, D. Qui, and A.S. Mandir Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice Proc Natl Acad Sci USA 99 2002 8968 8973 (Pubitemid 34693667)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.13
, pp. 8968-8973
-
-
Lee, M.K.1
Stirling, W.2
Xu, Y.3
Xu, E.4
Qui, D.5
Mandir, A.S.6
Dawson, T.M.7
Copeland, N.G.8
Jenkins, N.A.9
Price, D.L.10
-
264
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders
-
DOI 10.1126/science.287.5456.1265
-
E. Masliah, E. Rockenstein, I. Veinbergs, M. Mallory, M. Hashimoto, and A. Takeda Dopaminergic loss and inclusion body formation in α-synuclein mice: implications for neurodegenerative disorders Science 287 2000 1265 1269 (Pubitemid 30112148)
-
(2000)
Science
, vol.287
, Issue.5456
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
-
265
-
-
0036245056
-
Behavioral and neurochemical effects of wild-type and mutated human α-synuclein in transgenic mice
-
DOI 10.1006/exnr.2002.7882
-
E.K. Richfield, M.J. Thiruchelvam, D.A. Cory-Slechta, C. Wuetzer, R.R. Gainetdinov, and M.G. Caron Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice Exp Neurol 175 2002 35 48 (Pubitemid 34507908)
-
(2002)
Experimental Neurology
, vol.175
, Issue.1
, pp. 35-48
-
-
Richfield, E.K.1
Thiruchelvam, M.J.2
Cory-Slechta, D.A.3
Wuertzer, C.4
Gainetdinov, R.R.5
Caron, M.G.6
Di Monte, D.A.7
Federoff, H.J.8
-
266
-
-
0034663176
-
Neuropathology in mice expressing human α-synuclein
-
H. van der Putten, K.-H. Wiederhold, A. Probst, S. Barbieri, C. Mistl, and S. Danner Neuropathology in mice expressing human α-synuclein J Neurosci 20 2000 6021 6029 (Pubitemid 30658395)
-
(2000)
Journal of Neuroscience
, vol.20
, Issue.16
, pp. 6021-6029
-
-
Van Der Putten, H.1
Wiederhold, K.-H.2
Probst, A.3
Barbieri, S.4
Mistl, C.5
Danner, S.6
Kauffmann, S.7
Hofele, K.8
Spooren, W.P.J.M.9
Ruegg, M.A.10
Lin, S.11
Caroni, P.12
Sommer, B.13
Tolnay, M.14
Bilbe, G.15
-
267
-
-
39749196233
-
Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein
-
M. Wakamatsu, A. Ishii, S. Iwata, J. Sakagami, Y. Ukai, and M. Ono Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein Neurobiol Aging 29 2008 547 585
-
(2008)
Neurobiol Aging
, vol.29
, pp. 547-585
-
-
Wakamatsu, M.1
Ishii, A.2
Iwata, S.3
Sakagami, J.4
Ukai, Y.5
Ono, M.6
-
268
-
-
30644471051
-
Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
DOI 10.1523/JNEUROSCI.4308-05.2006
-
L.J. Martin, Y. Pan, A.C. Price, W. Sterling, N.G. Copeland, and N.A. Jenkins Parkinson's disease α-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death J Neurosci 26 2006 41 50 (Pubitemid 43089519)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.1
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
Sterling, W.4
Copeland, N.G.5
Jenkins, N.A.6
Price, D.L.7
Lee, M.K.8
-
269
-
-
0015197354
-
The axon reaction: A review of the principal features of perikaryal responses to axon injury
-
A.R. Lieberman The axon reaction: a review of the principal features of perikaryal responses to axon injury Int Rev Neurobiol 14 1971 49 124
-
(1971)
Int Rev Neurobiol
, vol.14
, pp. 49-124
-
-
Lieberman, A.R.1
-
270
-
-
14744305520
-
Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice - A model of familial Parkinson's disease
-
DOI 10.1016/j.nbd.2004.12.009
-
H.F. Poon, M. Frasier, N. Shreve, V. Calabrese, B. Wolozin, and D.A. Butterfield Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice - a model of familial Parkinson's disease Neurobiol Dis 18 2005 492 498 (Pubitemid 40332708)
-
(2005)
Neurobiology of Disease
, vol.18
, Issue.3
, pp. 492-498
-
-
Poon, H.F.1
Frasier, M.2
Shreve, N.3
Calabrese, V.4
Wolozin, B.5
Butterfield, D.A.6
-
271
-
-
0035873812
-
α-synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro
-
DOI 10.1016/S0891-5849(01)00513-5, PII S0891584901005135
-
S. Turnbull, B.J. Tabner, O.M. El-Agnaf, S. Moore, Y. Davies, and D. Allsop Alpha-synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro Free Radic Biol Med 30 2001 1163 1170 (Pubitemid 32441842)
-
(2001)
Free Radical Biology and Medicine
, vol.30
, Issue.10
, pp. 1163-1170
-
-
Turnbull, S.1
Tabner, B.J.2
El-Agnaf, O.M.A.3
Moore, S.4
Davies, Y.5
Allsop, D.6
-
272
-
-
0035887860
-
Induction of α-synuclein aggregation by intracellular nitrative insult
-
E. Paxinou, Q. Chen, M. Weisse, B.I. Giasson, E.H. Norris, and S.M. Rueter Induction of alpha-synuclein aggregation by intracellular nitrative insult J Neurosci 21 2001 8053 8061 (Pubitemid 32952762)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.20
, pp. 8053-8061
-
-
Paxinou, E.1
Chen, Q.2
Weisse, M.3
Giasson, B.I.4
Norris, E.H.5
Rueter, S.M.6
Trojanowski, J.Q.7
Lee, V.M.-Y.8
Ischiropoulos, H.9
-
273
-
-
0034674652
-
Dityrosine cross-linking promotes formation of stable α-synuclein polymers
-
J.M. Souza, B.I. Giasson, Q. Chen, V.M.-Y. Lee, and H. Ischiropoulos Dityrosine cross-linking promotes formation of stable α-synuclein polymers J Biol Chem 265 2000 18344 18349
-
(2000)
J Biol Chem
, vol.265
, pp. 18344-18349
-
-
Souza, J.M.1
Giasson, B.I.2
Chen, Q.3
Lee, V.M.-Y.4
Ischiropoulos, H.5
-
274
-
-
33845361630
-
Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: Mechanisms of mitochondriopathy and cell death
-
DOI 10.1002/cne.21160
-
L.J. Martin, Z. Liu, K. Chen, A.C. Price, Y. Pan, and J.A. Swaby Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death J Comp Neurol 500 2007 20 46 (Pubitemid 44904300)
-
(2007)
Journal of Comparative Neurology
, vol.500
, Issue.1
, pp. 20-46
-
-
Martin, L.J.1
Liu, Z.2
Chen, K.3
Price, A.C.4
Yan, P.5
Swaby, J.A.6
Golden, W.C.7
-
275
-
-
77950458426
-
Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice
-
K. Chen, F.J. Northington, and L.J. Martin Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice Brain Struct Funct 214 2010 219 234
-
(2010)
Brain Struct Funct
, vol.214
, pp. 219-234
-
-
Chen, K.1
Northington, F.J.2
Martin, L.J.3
-
277
-
-
0034864628
-
Apoptosis in amyotrophic lateral sclerosis: A review of the evidence
-
DOI 10.1046/j.0305-1846.2001.00332.x
-
S. Sathasivam, P.G. Ince, and P.J. Shaw Apoptosis in amyotrophic lateral sclerosis: a review of the evidence Neuropathol Appl Neurobiol 27 2001 257 274 (Pubitemid 32758614)
-
(2001)
Neuropathology and Applied Neurobiology
, vol.27
, Issue.4
, pp. 257-274
-
-
Sathasivam, S.1
Ince, P.G.2
Shaw, P.J.3
-
278
-
-
33646082251
-
Widespread loss of neuronal populations in spinal ventral horn in sporadic motor neuron disease. A morphometric study
-
B. Stephens, R.J. Guiloff, R. Navarrete, P. Newman, N. Nikhar, and P. Lewis Widespread loss of neuronal populations in spinal ventral horn in sporadic motor neuron disease. A morphometric study J Neurol Sci 244 2006 41 58
-
(2006)
J Neurol Sci
, vol.244
, pp. 41-58
-
-
Stephens, B.1
Guiloff, R.J.2
Navarrete, R.3
Newman, P.4
Nikhar, N.5
Lewis, P.6
-
279
-
-
2942532727
-
Cortical selective vulnerability in motor neuron disease: A morphometric study
-
DOI 10.1093/brain/awh132
-
S. Maekawa, S. Al-Sarraj, M. Kibble, S. Landau, J. Parnavelas, and D. Cotter Cortical selective vulnerability in motor neurons disease: a morphometric study Brain 127 2004 1237 1251 (Pubitemid 38745505)
-
(2004)
Brain
, vol.127
, Issue.6
, pp. 1237-1251
-
-
Maekawa, S.1
Al-Sarraj, S.2
Kibble, M.3
Landau, S.4
Parnavelas, J.5
Cotter, D.6
Everall, I.7
Leigh, P.N.8
-
281
-
-
42649120983
-
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
-
DOI 10.1038/ng.132, PII NG132
-
E. Kabashi, P.N. Valdmains, P. Dion, D. Spiegelman, B.J. McConkey, and C. Vande Velde TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis Nat Genet 40 2008 572 574 (Pubitemid 351601218)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 572-574
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
Spiegelman, D.4
McConkey, B.J.5
Velde, C.V.6
Bouchard, J.-P.7
Lacomblez, L.8
Pochigaeva, K.9
Salachas, F.10
Pradat, P.-F.11
Camu, W.12
Meininger, V.13
Dupre, N.14
Rouleau, G.A.15
-
282
-
-
0027426169
-
Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase
-
H.-X. Deng, A. Hentati, J.A. Tainer, Z. Iqbal, A. Cayabyab, and W.-Y. Hung Amyotrophic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase Science 261 1993 1047 1051 (Pubitemid 23300865)
-
(1993)
Science
, vol.261
, Issue.5124
, pp. 1047-1051
-
-
Deng, H.-X.1
Hentati, A.2
Tainer, J.A.3
Iqbal, Z.4
Cayabyab, A.5
Hung, W.-Y.6
Getzoff, E.D.7
Hu, P.8
Herzfeldt, B.9
Roos, R.P.10
Warner, C.11
Deng, G.12
Soriano, E.13
Smyth, C.14
Parge, H.E.15
Ahmed, A.16
Roses, A.D.17
Hallewell, R.A.18
Pericak-Vance, M.A.19
Siddique, T.20
more..
-
283
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
C. Vance, B. Rogelj, T. Hortobagyi, K.J. de Vos, A.L. Nishimura, and J. Sreedharan Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 Science 323 2009 1208 1211
-
(2009)
Science
, vol.323
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobagyi, T.3
De Vos, K.J.4
Nishimura, A.L.5
Sreedharan, J.6
-
285
-
-
58049192812
-
Deleterious variants of FIG4, a phosphoinositade phosphatase, in patients with ALS
-
C.Y. Chow, J.E. Lander, S.K. Bergren, P.C. Sapp, A.E. Grant, and J.M. Jones Deleterious variants of FIG4, a phosphoinositade phosphatase, in patients with ALS Am J Hum Genet 84 2009 85 88
-
(2009)
Am J Hum Genet
, vol.84
, pp. 85-88
-
-
Chow, C.Y.1
Lander, J.E.2
Bergren, S.K.3
Sapp, P.C.4
Grant, A.E.5
Jones, J.M.6
-
286
-
-
0033546228
-
Ultrastructural change of synapses of Betz cells in patients with amyotrophic lateral sclerosis
-
DOI 10.1016/S0304-3940(99)00374-2, PII S0304394099003742
-
S. Sasaki, and M. Iwata Ultrastructural changes of synapses of Betz cell in patients with amyotrophic lateral sclerosis Neurosci Lett 268 1999 29 32 (Pubitemid 29292537)
-
(1999)
Neuroscience Letters
, vol.268
, Issue.1
, pp. 29-32
-
-
Sasaki, S.1
Iwata, M.2
-
287
-
-
0036176613
-
Mitochondrial involvement in amyotrophic lateral sclerosis
-
DOI 10.1016/S0197-0186(01)00125-5, PII S0197018601001255
-
F.M. Menzies, P.G. Ince, and P.J. Shaw Mitochondrial involvement in amyotrophic lateral sclerosis Neurochem Int 40 2002 543 551 (Pubitemid 34159155)
-
(2002)
Neurochemistry International
, vol.40
, Issue.6
, pp. 543-551
-
-
Menzies, F.M.1
Ince, P.G.2
Shaw, P.J.3
-
288
-
-
0031915174
-
Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease
-
DOI 10.1002/ana.410430119
-
G.P. Comi, A. Bordoni, S. Salani, L. Franeschina, M. Sciacco, and A. Prelle Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease Ann Neurol 43 1998 110 116 (Pubitemid 28124656)
-
(1998)
Annals of Neurology
, vol.43
, Issue.1
, pp. 110-116
-
-
Comi, G.P.1
Bordoni, A.2
Salani, S.3
Franceschina, L.4
Sciacco, M.5
Prelle, A.6
Fortunato, F.7
Zeviani, M.8
Napoli, L.9
Bresolin, N.10
Moggio, M.11
Ausenda, C.D.12
Taanman, J.-W.13
Scarlato, G.14
-
289
-
-
33644832850
-
Ile mutation
-
DOI 10.1002/ana.20758
-
G.M. Borthwick, R.W. Taylo, T.J. Walls, K. Tonska, G.A. Taylor, and P.J. Shaw Motor neuron disease in a patient with a mitochondrial tRNAIle mutation Ann Neurol 59 2006 570 574 (Pubitemid 43358082)
-
(2006)
Annals of Neurology
, vol.59
, Issue.3
, pp. 570-574
-
-
Borthwick, G.M.1
Taylor, R.W.2
Walls, T.J.3
Tonska, K.4
Taylor, G.A.5
Shaw, P.J.6
Ince, P.G.7
Turnbull, D.M.8
-
290
-
-
2342520177
-
Single-cell analysis of mtDNA deletion levels in sporadic amyotrophic lateral sclerosis
-
DOI 10.1097/00001756-200404290-00002
-
C. Mawrin, E. Kirches, G. Krause, F.R. Wiedemann, C.K. Vorwerk, and B. Bogerts Single-cell analysis of mtDNA levels in sporadic amyotrophic lateral sclerosis Neuroreport 15 2004 939 943 (Pubitemid 38591239)
-
(2004)
NeuroReport
, vol.15
, Issue.6
, pp. 939-943
-
-
Mawrin, C.1
Kirches, E.2
Krause, G.3
Wiedemann, F.R.4
Vorwerk, C.K.5
Bogerts, B.6
Schildhaus, H.-U.7
Dietzmann, K.8
Schneider-Stock, R.9
-
291
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson's disease
-
A. Bender, K.J. Krishnan, C.M. Morris, G.A. Taylor, A.K. Reve, and R.P. Perry High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson's disease Nat Genet 38 2006 515 517
-
(2006)
Nat Genet
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reve, A.K.5
Perry, R.P.6
-
292
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Y. Kraytsberg, E. Kudryavtseva, A.C. McKee, C. Geula, N.W. Kowall, and K. Khrapko Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons Nat Genet 38 2006 518 520
-
(2006)
Nat Genet
, vol.38
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
294
-
-
0030026832
-
Ultrastructural evidence for altered calcium in motor nerve terminals in amyotrophic lateral sclerosis
-
DOI 10.1002/ana.410390210
-
L. Siklos, J. Engelhardt, Y. Harat, R.G. Smith, F. Joo, and S.H. Appel Ultrastructural evidence for altered calcium in motor nerve terminals in amyotrophic lateral sclerosis Ann Neurol 39 1996 203 216 (Pubitemid 26071571)
-
(1996)
Annals of Neurology
, vol.39
, Issue.2
, pp. 203-216
-
-
Siklos, L.1
Engelhardt, J.2
Harati, Y.3
Smith, R.G.4
Joo, F.5
Appel, S.H.6
-
295
-
-
0026597010
-
Decreased glutamate transport by brain and spinal cord in amyotrophic lateral sclerosis
-
J.D. Rothstein, L.J. Martin, and R.W. Kuncl Decreased glutamate transport by brain and spinal cord in amyotrophic lateral sclerosis N Engl J Med 326 1992 1464 1468
-
(1992)
N Engl J Med
, vol.326
, pp. 1464-1468
-
-
Rothstein, J.D.1
Martin, L.J.2
Kuncl, R.W.3
-
296
-
-
0029030610
-
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
-
J.D. Rothstein, M. Van Kammen, A.I. Levey, L.J. Martin, and R.W. Kuncl Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis Ann Neurol 38 1995 73 84
-
(1995)
Ann Neurol
, vol.38
, pp. 73-84
-
-
Rothstein, J.D.1
Van Kammen, M.2
Levey, A.I.3
Martin, L.J.4
Kuncl, R.W.5
-
297
-
-
0037038109
-
Quantitative assessment of AMPA receptor mRNA in human spinal motor neurons isolated by laser capture microdissection
-
P.R. Heath, J. Tomkins, P.G. Ince, and P.J. Shaw Quantitative assessment of AMPA receptor mRNA in human spinal motor neurons isolated by laser capture microdissection Neuroreport 13 2002 1753 1757 (Pubitemid 35333155)
-
(2002)
NeuroReport
, vol.13
, Issue.14
, pp. 1753-1757
-
-
Heath, P.R.1
Tomkins, J.2
Ince, P.G.3
Shaw, P.J.4
-
298
-
-
15044346521
-
Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis
-
DOI 10.1007/s00109-004-0599-z
-
S. Kwak, and Y. Kawahara Deficient RNA editing of GluR2 and neuronal death in amyotrophic lateral sclerosis J Mol Med 83 2005 110 120 (Pubitemid 40379299)
-
(2005)
Journal of Molecular Medicine
, vol.83
, Issue.2
, pp. 110-120
-
-
Kwak, S.1
Kawahara, Y.2
-
299
-
-
33845927357
-
Mitochondrial trafficking and morphology in healthy and injured neurons
-
DOI 10.1016/j.pneurobio.2006.09.003, PII S0301008206001109
-
D.T.W. Chang, and I.J. Reynolds Mitochondrial trafficking and morphology in healthy and injured neurons Prog Brain Res 80 2006 241 268 (Pubitemid 46028946)
-
(2006)
Progress in Neurobiology
, vol.80
, Issue.5
, pp. 241-268
-
-
Chang, D.T.W.1
Reynolds, I.J.2
-
300
-
-
46449116985
-
Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition
-
M.J. Hansson, R. Mansson, S. Morota, H. Uchino, T. Kallur, and T. Sumi Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition Free Radic Biol Med 45 2008 284 294
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 284-294
-
-
Hansson, M.J.1
Mansson, R.2
Morota, S.3
Uchino, H.4
Kallur, T.5
Sumi, T.6
-
301
-
-
1542346966
-
2+ levels in brainstem motoneurones from mouse
-
DOI 10.1113/jphysiol.2003.053900
-
2 + levels in brainstem motoneurones J Physiol 555 2004 45 59 (Pubitemid 38324500)
-
(2004)
Journal of Physiology
, vol.555
, Issue.1
, pp. 45-59
-
-
Bergmann, F.1
Keller, B.U.2
-
302
-
-
0036570159
-
Oxidatively modified proteins in aging and disease
-
DOI 10.1016/S0891-5849(02)00780-3, PII S0891584902007803
-
M.F. Beal Oxidatively modified protein in aging and disease Free Radic Biol Med 32 2002 797 803 (Pubitemid 34439250)
-
(2002)
Free Radical Biology and Medicine
, vol.32
, Issue.9
, pp. 797-803
-
-
Beal M.Flint1
-
303
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
R.J. Ferrante, S.E. Browne, L.A. Shinobu, A.C. Bowling, M.J. Baik, and U. MacGarvey Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis J Neurochem 69 1997 2064 2074 (Pubitemid 27452754)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.5
, pp. 2064-2074
-
-
Ferrante, R.J.1
Browne, S.E.2
Shinobu, L.A.3
Bowling, A.C.4
Baik, M.J.5
MacGarvey, U.6
Kowall, N.W.7
Brown Jr., R.H.8
Beal, M.F.9
-
304
-
-
0028971936
-
Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis
-
K. Abe, L.-H. Pan, M. Watanabe, T. Kato, and Y. Itoyama Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis Neurosci Lett 199 1995 152 154
-
(1995)
Neurosci Lett
, vol.199
, pp. 152-154
-
-
Abe, K.1
Pan, L.-H.2
Watanabe, M.3
Kato, T.4
Itoyama, Y.5
-
305
-
-
0030851761
-
Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis
-
DOI 10.1002/ana.410420416
-
M.F. Beal, R.J. Ferrante, S.E. Browne, R.T. Matthews, N.W. Kowall, and R.H. Brown Jr. Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis Ann Neurol 42 1997 644 654 (Pubitemid 27439028)
-
(1997)
Annals of Neurology
, vol.42
, Issue.4
, pp. 644-654
-
-
Beal, M.F.1
Ferrante, R.J.2
Browne, S.E.3
Matthews, R.T.4
Kowall, N.W.5
Brown Jr., R.H.6
-
306
-
-
0034836440
-
Inducible nitric oxide synthase (iNOS) and nitrotyrosine immunoreactivity in the spinal cords of transgenic mice with a G93A mutant SOD1 gene
-
S. Sasaki, H. Warita, K. Abe, and M. Iwata Inducible nitric oxide synthase (iNOS) and nitrotyrosine immunoreactivity in the spinal cords of transgenic mice with mutant SOD1 gene J Neuropathol Exp Neurol 60 2001 839 846 (Pubitemid 32880591)
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, Issue.9
, pp. 839-846
-
-
Sasaki, S.1
Warita, H.2
Abe, K.3
Iwata, M.4
-
307
-
-
0031865772
-
Metabolic dysfunction in familial, but not sporadic, amyotrophic lateral sclerosis
-
S.E. Browne, A.C. Bowling, M.J. Baik, M. Gurney, R.H. Brown Jr., and M.F. Beal Metabolic dysfunction in familial, but not sporadic, amyotrophic lateral sclerosis J Neurochem 71 1998 281 287 (Pubitemid 28292560)
-
(1998)
Journal of Neurochemistry
, vol.71
, Issue.1
, pp. 281-287
-
-
Browne, S.E.1
Bowling, A.C.2
Baik, M.J.3
Gurney, M.4
Brown Jr., R.H.5
Beal, M.F.6
-
308
-
-
0032745071
-
Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death
-
DOI 10.1002/1531-8249(199911)46:5<787::AID-ANA17>3.0.CO;2-8
-
G.M. Borthwick, M.A. Johnson, P.G. Ince, P.J. Shaw, and D.M. Turnbull Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death Ann Neurol 46 1999 787 790 (Pubitemid 29518143)
-
(1999)
Annals of Neurology
, vol.46
, Issue.5
, pp. 787-790
-
-
Borthwick, G.M.1
Johnson, M.A.2
Ince, P.G.3
Shaw, P.J.4
Turnbull, D.M.5
-
309
-
-
0033917463
-
Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis
-
S. Vielhaber, D. Kunz, K. Winkler, F.R. Wiedemann, E. Kirches, and H. Feistner Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis Brain 123 2000 1339 1348 (Pubitemid 30420935)
-
(2000)
Brain
, vol.123
, Issue.7
, pp. 1339-1348
-
-
Vielhaber, S.1
Kunz, D.2
Winkler, K.3
Wiedemann, F.R.4
Kirches, E.5
Feistner, H.6
Heinze, H.-J.7
Elger, C.E.8
Schubert, W.9
Kunz, W.S.10
-
310
-
-
33847767167
-
Activities of mitochondrial complexes correlate with nNOS amount in muscle from ALS patients
-
DOI 10.1111/j.1365-2990.2006.00791.x
-
G. Soraru, L. Vergani, L. Fedrizzi, C. D'Ascenzo, A. Polo, and B. Bernazzi Activities of mitochondrial complexes correlate with nNOS amount in muscle from ALS patients Neuropathol Appl Neurobiol 33 2007 204 211 (Pubitemid 46385714)
-
(2007)
Neuropathology and Applied Neurobiology
, vol.33
, Issue.2
, pp. 204-211
-
-
Soraru, G.1
Vergani, L.2
Fedrizzi, L.3
D'Ascenzo, C.4
Polo, A.5
Bernazzi, B.6
Angelini, C.7
-
311
-
-
32644434546
-
Muscular mitochondrial function in amyotrophic lateral sclerosis is progressively altered as the disease develops: A temporal study in man
-
DOI 10.1016/j.expneurol.2005.07.020, PII S0014488605002694
-
A. Echaniz-Laguna, J. Zoll, E. Ponsot, B. N'Guessan, C. Tranchant, and J.-P. Loeffler Muscular mitochondrial function in amyotrophic lateral sclerosis is progressively altered as the disease develops: a temporal study in man Exp Neurol 198 2006 25 30 (Pubitemid 43243741)
-
(2006)
Experimental Neurology
, vol.198
, Issue.1
, pp. 25-30
-
-
Echaniz-Laguna, A.1
Zoll, J.2
Ponsot, E.3
N'Guessan, B.4
Tranchant, C.5
Loeffler, J.-P.6
Lampert, E.7
-
312
-
-
0032896327
-
Neuronal death in amyotrophic lateral sclerosis is apoptosis: Possible contribution of a programmed cell death mechanism
-
L.J. Martin Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism J Neuropathol Exp Neurol 58 1999 459 471 (Pubitemid 29220739)
-
(1999)
Journal of Neuropathology and Experimental Neurology
, vol.58
, Issue.5
, pp. 459-471
-
-
Martin, L.J.1
-
313
-
-
23744460521
-
Opportunities for neuroprotection in ALS using cell death mechanism rationales
-
DOI 10.1016/j.ddmod.2004.09.004
-
L.J. Martin, and Z. Liu Opportunities for neuroprotection in ALS using cell death mechanism rationales Drug Discov Today 1 2004 135 143 (Pubitemid 41123763)
-
(2004)
Drug Discovery Today: Disease Models
, vol.1
, Issue.2
, pp. 135-143
-
-
Martin, L.J.1
Liu, Z.2
-
314
-
-
77955397778
-
Cell and tissue microdissection in combination with genomic and proteomic profiling
-
L. Zaborszky, F.G. Wouterlood, J.L. Lanciego, Springer New York
-
S.D. Ginsberg, S.E. Hemby, E.J. Mufson, and L.J. Martin Cell and tissue microdissection in combination with genomic and proteomic profiling L. Zaborszky, F.G. Wouterlood, J.L. Lanciego, Neuroanatomical tract-tracing 3, molecules, neurons, and systems 2006 Springer New York 109 141
-
(2006)
Neuroanatomical Tract-tracing 3, Molecules, Neurons, and Systems
, pp. 109-141
-
-
Ginsberg, S.D.1
Hemby, S.E.2
Mufson, E.J.3
Martin, L.J.4
-
315
-
-
0034517935
-
P53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis
-
DOI 10.1006/nbdi.2000.0314
-
L.J. Martin p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis Neurobiol Dis 7 2000 613 622 (Pubitemid 32044286)
-
(2000)
Neurobiology of Disease
, vol.7
, Issue.6
, pp. 613-622
-
-
Martin, L.J.1
-
316
-
-
27844463209
-
The apoptosis-necrosis cell death continuum in CNS development, injury and disease: Contributions and mechanisms
-
E.H. Lo, J. Marwah, Prominent Press Scottsdale, AZ
-
L.J. Martin The apoptosis-necrosis cell death continuum in CNS development, injury and disease: contributions and mechanisms E.H. Lo, J. Marwah, Neuroprotection 2002 Prominent Press Scottsdale, AZ 379 412
-
(2002)
Neuroprotection
, pp. 379-412
-
-
Martin, L.J.1
-
317
-
-
0033630642
-
Mechanisms for neuronal degeneration in amyotrophic lateral sclerosis and in models of motor neuron death
-
L.J. Martin, A.C. Price, A. Kaiser, A.Y. Shaikh, and Z. Liu Mechanisms for neuronal degeneration in amyotrophic lateral sclerosis and in models of motor neuron death Int J Mol Med 5 2000 3 13
-
(2000)
Int J Mol Med
, vol.5
, pp. 3-13
-
-
Martin, L.J.1
Price, A.C.2
Kaiser, A.3
Shaikh, A.Y.4
Liu, Z.5
-
318
-
-
0035953172
-
Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy
-
DOI 10.1002/cne.1087
-
Z. Liu, and L.J. Martin Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy J Comp Neurol 432 2001 35 60 (Pubitemid 32187019)
-
(2001)
Journal of Comparative Neurology
, vol.432
, Issue.1
, pp. 35-60
-
-
Liu, Z.1
Martin, L.J.2
-
319
-
-
77953530958
-
Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice
-
M. Wong, and L.J. Martin Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice Hum Mol Genet 9 2010 2284 2302
-
(2010)
Hum Mol Genet
, vol.9
, pp. 2284-2302
-
-
Wong, M.1
Martin, L.J.2
-
320
-
-
42249102078
-
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
-
B.J. Turner, and K. Talbot Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS Prog Neurobiol 85 2008 94 134
-
(2008)
Prog Neurobiol
, vol.85
, pp. 94-134
-
-
Turner, B.J.1
Talbot, K.2
-
321
-
-
0014691242
-
Superoxide dismutase, an enzymic function for erythrocuprein (hemocuprein)
-
J.M. McCord, and I. Fridovich Superoxide dismutase, an enzymic function for erythrocuprein (hemocuprein) J Biol Chem 244 1969 6049 6055
-
(1969)
J Biol Chem
, vol.244
, pp. 6049-6055
-
-
McCord, J.M.1
Fridovich, I.2
-
322
-
-
2442624720
-
Monomeric Cu,Zn-superoxide Dismutase Is a Common Misfolding Intermediate in the Oxidation Models of Sporadic and Familial Amyotrophic Lateral Sclerosis
-
DOI 10.1074/jbc.M313295200
-
R. Rakhit, J.P. Crow, J.R. Lepock, L.H. Kondejewski, N.R. Cashman, and A. Chakrabartty Monomeric Cu, Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic sclerosis J Biol Chem 279 2004 15499 15504 (Pubitemid 38618950)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.15
, pp. 15499-15504
-
-
Rakhit, R.1
Crow, J.P.2
Lepock, J.R.3
Kondejewski, L.H.4
Cashman, N.R.5
Chakrabartty, A.6
-
323
-
-
33748795566
-
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials
-
DOI 10.1073/pnas.0605814103
-
A. Ferri, M. Cozzolino, C. Crosio, M. Nencini, A. Casciati, and E.B. Gralla Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials Proc Natl Acad Sci USA 103 2006 13860 13865 (Pubitemid 44413998)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.37
, pp. 13860-13865
-
-
Ferri, A.1
Cozzolino, M.2
Crosio, C.3
Nencini, M.4
Casciati, A.5
Gralla, E.B.6
Rotilio, G.7
Valentine, J.S.8
Carri, M.T.9
-
324
-
-
0039251419
-
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase
-
A.G. Estévez, J.P. Crow, J.B. Sampson, C. Reiter, Y. Zhuang, and G.J. Richardson Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase Science 286 1999 2498 2500
-
(1999)
Science
, vol.286
, pp. 2498-2500
-
-
Estévez, A.G.1
Crow, J.P.2
Sampson, J.B.3
Reiter, C.4
Zhuang, Y.5
Richardson, G.J.6
-
325
-
-
0036071852
-
Overexpression of manganese superoxide dismutase attenuates neuronal death in human cells expressing mutant (G37R) Cu/Zn-superoxide dismutase
-
DOI 10.1046/j.1471-4159.2002.00812.x
-
S.W. Flanagan, R.D. Anderson, M.A. Ross, and L.W. Oberley Overexpression of manganese superoxide dismutase attenuates neuronal death in human cells expressing mutant (G37R) Cu/Zn-superoxide dismutase J Neurochem 81 2002 170 177 (Pubitemid 34808864)
-
(2002)
Journal of Neurochemistry
, vol.81
, Issue.1
, pp. 170-177
-
-
Flanagan, S.W.1
Anderson, R.D.2
Ross, M.A.3
Oberley, L.W.4
-
326
-
-
55849091446
-
Expression of mutant SOD1G93A in astrocytes induces functional deficits in motoneuron mitochondria
-
L.G. Bilsland, N. Nirmalananthan, J. Yip, L. Greensmith, and M.R. Duhcen Expression of mutant SOD1G93A in astrocytes induces functional deficits in motoneuron mitochondria J Neurochem 107 2008 1271 1283
-
(2008)
J Neurochem
, vol.107
, pp. 1271-1283
-
-
Bilsland, L.G.1
Nirmalananthan, N.2
Yip, J.3
Greensmith, L.4
Duhcen, M.R.5
-
327
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
-
M.E. Gurney, H. Pu, A.Y. Chiu, M.C. Dal Canto, C.Y. Polchow, and D.D. Alexander Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation Science 264 1994 1772 1775 (Pubitemid 24227760)
-
(1994)
Science
, vol.264
, Issue.5166
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.-X.10
Chen, W.11
Zhai, P.12
Sufit, R.L.13
Siddique, T.14
-
328
-
-
0027946294
-
Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
-
M.C. Dal Canto, and M.E. Gurney Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis Am J Pathol 145 1994 1271 1279 (Pubitemid 24378480)
-
(1994)
American Journal of Pathology
, vol.145
, Issue.6
, pp. 1271-1279
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
329
-
-
59649104173
-
Glycinergic innervation of motoneurons is deficient in amyotrophic lateral sclerosis mice: A confocal quantitative analysis
-
Q. Chang, and L.J. Martin Glycinergic innervation of motoneurons is deficient in amyotrophic lateral sclerosis mice: a confocal quantitative analysis Am J Pathol 174 2009 574 585
-
(2009)
Am J Pathol
, vol.174
, pp. 574-585
-
-
Chang, Q.1
Martin, L.J.2
-
330
-
-
0035886428
-
Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity
-
DOI 10.1016/S0022-510X(01)00627-X, PII S0022510X0100627X
-
C. Bendotti, N. Calvaresi, L. Chiveri, A. Prelle, M. Moggio, and M. Braga Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity J Neurol Sci 191 2001 25 33 (Pubitemid 33035892)
-
(2001)
Journal of the Neurological Sciences
, vol.191
, Issue.1-2
, pp. 25-33
-
-
Bendotti, C.1
Calvaresi, N.2
Chiveri, L.3
Prelle, A.4
Moggio, M.5
Braga, M.6
Silani, V.7
De Biasi, S.8
-
331
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
P.C. Wong, C.A. Pardo, D.R. Borchelt, M.K. Lee, N.G. Copeland, and N.A. Jenkins An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria Neuron 14 1995 1105 1116
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
Lee, M.K.4
Copeland, N.G.5
Jenkins, N.A.6
-
332
-
-
0032079517
-
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
-
J. Kong, and Z. Xu Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1 J Neurosci 18 1998 3241 3250 (Pubitemid 28186017)
-
(1998)
Journal of Neuroscience
, vol.18
, Issue.9
, pp. 3241-3250
-
-
Kong, J.1
Xu, Z.2
-
333
-
-
0034821922
-
CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations
-
D. Jaarsma, F. Rognoni, W. van Duijn, H.W. Verspaget, E.D. Haasdijk, and J.C. Holstege CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations Acta Neuropathol 102 2001 293 305 (Pubitemid 32894698)
-
(2001)
Acta Neuropathologica
, vol.102
, Issue.4
, pp. 293-305
-
-
Jaarsma, D.1
Rognoni, F.2
Van Duijn, W.3
Verspaget, H.W.4
Haasdijk, E.D.5
Holstege, J.C.6
-
334
-
-
2342442179
-
Ultrastructural study mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene
-
DOI 10.1007/s00401-004-0837-z
-
S. Sasaki, H. Warita, T. Murakami, K. Abe, and M. Iwata Ultrastructural study of mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene Acta Neuropathol 107 2004 461 474 (Pubitemid 38559256)
-
(2004)
Acta Neuropathologica
, vol.107
, Issue.5
, pp. 461-474
-
-
Sasaki, S.1
Warita, H.2
Murakami, T.3
Abe, K.4
Iwata, M.5
-
335
-
-
0027965073
-
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity
-
DOI 10.1073/pnas.91.17.8292
-
D.R. Borchelt, M.K. Lee, H.H. Slunt, M. Guarnieri, Z.-S. Xu, and P.C. Wong Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity Proc Natl Acad Sci USA 91 1994 8292 8296 (Pubitemid 24253933)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.17
, pp. 8292-8296
-
-
Borchelt, D.R.1
Lee, M.K.2
Slunt, H.S.3
Guarnieri, M.4
Xu, Z.-S.5
Wong, P.C.6
Brown Jr., R.H.7
Price, D.L.8
Sisodia, S.S.9
Cleveland, D.W.10
-
336
-
-
0029939471
-
A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn- superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in K(m) for hydrogen peroxide
-
DOI 10.1073/pnas.93.12.5709
-
M.B. Yim, J.-H. Kang, H.-S. Yim, H.-S. Kwak, P.B. Chock, and E.R. Stadtman A gain-of-function of an amyotrophic lateral sclerosis-associated Cu, Zn-superoxide dismutase mutant: an enhancement of free radical formation due to a decrease in Km for hydrogen peroxide Proc Natl Acad Sci USA 93 1996 5709 5714 (Pubitemid 26190744)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.12
, pp. 5709-5714
-
-
Moon Bin Yim1
Kang, J.-H.2
Yim, H.-S.3
Kwak, H.-S.4
Chock, P.B.5
Stadtman, E.R.6
-
337
-
-
37849007550
-
Oxidized/misfolded superoxide dismutase-1: The cause of all amyotrophic lateral sclerosis?
-
E. Kabashi, P.N. Valdmanis, P. Dion, and G.A. Rouleau Oxidized/misfolded superoxide dismutase-1: the cause of all amyotrophic lateral sclerosis? Ann Neurol 62 2007 553 559
-
(2007)
Ann Neurol
, vol.62
, pp. 553-559
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
Rouleau, G.A.4
-
338
-
-
34250177650
-
Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation
-
DOI 10.1111/j.1471-4159.2007.04531.x
-
S.A. Ezzi, M. Urushitani, and J.-P. Julien Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation J Neurochem 102 2007 170 178 (Pubitemid 46906269)
-
(2007)
Journal of Neurochemistry
, vol.102
, Issue.1
, pp. 170-178
-
-
Ezzi, S.A.1
Urushitani, M.2
Julien, J.-P.3
-
339
-
-
0038707391
-
Mutant Cu,Zn superoxide dismutases and familial amyotrophic lateral sclerosis: Evaluation of oxidative hypotheses
-
DOI 10.1016/S0891-5849(03)00153-9
-
S.I. Liochev, and I. Fridovich Mutant Cu, Zn superoxide dismutases and familial amyotrophic lateral sclerosis: evaluation of oxidative hypotheses Free Radic Biol Med 34 2003 1383 1389 (Pubitemid 36570411)
-
(2003)
Free Radical Biology and Medicine
, vol.34
, Issue.11
, pp. 1383-1389
-
-
Liochev, S.I.1
Fridovich, I.2
-
340
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
DOI 10.1152/physrev.00029.2006
-
P. Pacher, J.S. Beckman, and L. Liaudet Nitric oxide and peroxynitrite in health and disease Physiol Rev 87 2007 315 424 (Pubitemid 46217686)
-
(2007)
Physiological Reviews
, vol.87
, Issue.1
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
341
-
-
0031784348
-
Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
P.K. Andrus, T.J. Fleck, M.E. Gurney, and E.D. Hall Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis J Neurochem 71 1998 2041 2048 (Pubitemid 28491560)
-
(1998)
Journal of Neurochemistry
, vol.71
, Issue.5
, pp. 2041-2048
-
-
Andrus, P.K.1
Fleck, T.J.2
Gurney, M.E.3
Hall, E.D.4
-
342
-
-
22544448129
-
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice - A model of familial amyotrophic lateral sclerosis
-
H.F. Poon, K. Hensley, V. Thongboonkerd, M.L. Merchant, B.C. Lynn, and W.M. Pierce Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice - a model of familial amyotrophic lateral sclerosis Free Radic Biol Med 39 2005 435 462
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 435-462
-
-
Poon, H.F.1
Hensley, K.2
Thongboonkerd, V.3
Merchant, M.L.4
Lynn, B.C.5
Pierce, W.M.6
-
343
-
-
0035914342
-
Subcellular distribution of superoxide (SOD) in rat liver
-
A. Okado-Matsumoto, and I. Fridovich Subcellular distribution of superoxide (SOD) in rat liver J Biol Chem 276 2001 38388 38393
-
(2001)
J Biol Chem
, vol.276
, pp. 38388-38393
-
-
Okado-Matsumoto, A.1
Fridovich, I.2
-
344
-
-
0037088793
-
Mutant Cu Zn Superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS
-
C.M.J. Higgins, C. Jung, H. Ding, and Z. Xu Mutant Cu Zn Superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS J Neurosci 22 RC215 2002 1 6
-
(2002)
J Neurosci
, vol.22
, Issue.RC215
, pp. 1-6
-
-
Higgins, C.M.J.1
Jung, C.2
Ding, H.3
Xu, Z.4
-
345
-
-
3242703300
-
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria
-
DOI 10.1016/j.neuron.2004.06.021, PII S0896627304003915
-
P. Pasinelli, M.E. Belford, N. Lennon, B.J. Bacskai, B.T. Hyman, and D. Trotti Amyotrophic lateral sclerosis-associated SOD1 mutant protein bind and aggregate with Bcl-2 in spinal cord mitochondria Neuron 43 2004 19 30 (Pubitemid 38952816)
-
(2004)
Neuron
, vol.43
, Issue.1
, pp. 19-30
-
-
Pasinelli, P.1
Belford, M.E.2
Lennon, N.3
Bacskai, B.J.4
Hyman, B.T.5
Trotti, D.6
Brown Jr., R.H.7
-
346
-
-
43749099217
-
Deleterious role of superoxide dismutase in the mitochondrial intermembrane space
-
G. Goldsteins, V. Keksa-Goldsteine, T. Ahtiniemi, M. Jaronen, E. Arens, and K. Akerman Deleterious role of superoxide dismutase in the mitochondrial intermembrane space J Biol Chem 283 2008 8446 8452
-
(2008)
J Biol Chem
, vol.283
, pp. 8446-8452
-
-
Goldsteins, G.1
Keksa-Goldsteine, V.2
Ahtiniemi, T.3
Jaronen, M.4
Arens, E.5
Akerman, K.6
-
347
-
-
0344240348
-
ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes
-
C.M. Higgins, C. Jung, and Z. Xu ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes BMC Neurosci 4 2003 16
-
(2003)
BMC Neurosci
, vol.4
, pp. 16
-
-
Higgins, C.M.1
Jung, C.2
Xu, Z.3
-
348
-
-
35548991459
-
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
-
DOI 10.1093/hmg/ddm226
-
K.J. De Vos, A.L. Chapman, M.E. Tennant, C. Manser, E.L. Tudor, and K.-F. Lau Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondrial content Hum Mol Genet 16 2007 2720 2728 (Pubitemid 350018514)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.22
, pp. 2720-2728
-
-
De Vos, K.J.1
Chapman, A.L.2
Tennant, M.E.3
Manser, C.4
Tudor, E.L.5
Lau, K.-F.6
Brownlees, J.7
Ackerley, S.8
Shaw, P.J.9
Mcloughlin, D.M.10
Shaw, C.E.11
Leigh, P.N.12
Miller, C.C.J.13
Grierson, A.J.14
-
349
-
-
21844470751
-
Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation
-
DOI 10.1523/JNEUROSCI.0911-05.2005
-
L.J. Martin, K. Chen, and Z. Liu Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation J Neurosci 25 2005 6449 6459 (Pubitemid 40962540)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.27
, pp. 6449-6459
-
-
Martin, L.J.1
Chen, K.2
Liu, Z.3
-
350
-
-
0031801922
-
Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice
-
L. Siklos, J.I. Engelhardt, M.E. Alexianu, M.E. Gurney, T. Siddique, and S.H. Appel Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice J Neuropathol Exp Neurol 57 1998 571 587 (Pubitemid 28265600)
-
(1998)
Journal of Neuropathology and Experimental Neurology
, vol.57
, Issue.6
, pp. 571-587
-
-
Siklos, L.1
Engelhardt, J.I.2
Alexianu, M.E.3
Gurney, M.E.4
Siddique, T.5
Appel, S.H.6
-
353
-
-
0034623301
-
INOS and nitrotyrosine immunoreactivity in amyotrophic lateral sclerosis
-
DOI 10.1016/S0304-3940(00)01370-7, PII S0304394000013707
-
S. Sasaki, N. Shibata, T. Komori, and M. Iwata iNOS and nitrotyrosine immunoreactivity in amyotrophic lateral sclerosis Neurosci Lett 291 2000 44 48 (Pubitemid 30658109)
-
(2000)
Neuroscience Letters
, vol.291
, Issue.1
, pp. 44-48
-
-
Sasaki, S.1
Shibata, N.2
Komori, T.3
Iwata, M.4
-
354
-
-
77955358107
-
Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis
-
L.J. Martin Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis IDrugs 13 2010 568 580
-
(2010)
IDrugs
, vol.13
, pp. 568-580
-
-
Martin, L.J.1
-
355
-
-
0037252466
-
Different metabolic properties of mitochondrial oxidative phosphorylation in different cell types - Important implications for mitochondrial cytopathies
-
DOI 10.1113/eph8802512
-
W.S. Kunz Different metabolic properties of mitochondrial oxidative phosphorylation in different cell types - important implications for mitochondrial cytopathies Exp Physiol 88 1 2003 149 154 (Pubitemid 36150068)
-
(2003)
Experimental Physiology
, vol.88
, Issue.1
, pp. 149-154
-
-
Kunz, W.S.1
-
356
-
-
0035896440
-
Intrathecal cyclosporin prolongs survival of late-stage ALS mice
-
M. Keep, E. Elmér, K.S.K. Fong, and K. Csiszar Intrathecal cyclosporin prolongs survival of late-stage ALS mice Brain Res 894 2001 27 331
-
(2001)
Brain Res
, vol.894
, pp. 27-331
-
-
Keep, M.1
Elmér, E.2
Fong, K.S.K.3
Csiszar, K.4
-
357
-
-
3042511616
-
Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis
-
J. Karlsson, K.S. Fong, M.J. Hansson, E. Elmer, K. Csiszar, and M.F. Keep Life span extension and reduced neuronal death after weekly intraventricular cyclosporine injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis J Neurosurg 101 2004 128 137 (Pubitemid 38808472)
-
(2004)
Journal of Neurosurgery
, vol.101
, Issue.1
, pp. 128-137
-
-
Karlsson, J.1
Fong, K.S.K.2
Hansson, M.J.3
Elmer, E.4
Csiszar, K.5
Keep, M.F.6
-
358
-
-
1042289650
-
An ALS mouse model with a permeable blood-brain barrier benefits from systemic cyclosporine A treatment
-
I.G. Kirkinezos, D. Hernandez, W.G. Bradley, and C.T. Moraes An ALS mouse model with a permeable blood-brain barrier benefits from systemic cyclosporine A treatment J Neurochem 88 2004 821 826 (Pubitemid 38199302)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.4
, pp. 821-826
-
-
Kirkinezos, I.G.1
Hernandez, D.2
Bradley, W.G.3
Moraes, C.T.4
-
359
-
-
34547123812
-
Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis
-
DOI 10.1124/jpet.107.123000
-
T. Bordet, B. Buisson, M. Michaud, C. Drouot, P. Galea, and P. Delaage Identification and characterization of Cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis J Pharmacol Exp Ther 322 2007 709 720 (Pubitemid 47105813)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.322
, Issue.2
, pp. 709-720
-
-
Bordet, T.1
Buisson, B.2
Michaud, M.3
Drouot, C.4
Galea, P.5
Delaage, P.6
Akentieva, N.P.7
Evers, A.S.8
Covey, D.F.9
Ostuni, M.A.10
Lacapere, J.-J.11
Massaad, C.12
Schumacher, M.13
Steidl, E.-M.14
Maux, D.15
Delaage, M.16
Henderson, C.E.17
Pruss, R.M.18
-
360
-
-
40549116380
-
Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats
-
DOI 10.1111/j.1460-9568.2008.06065.x
-
C. Mills, M. Makwana, A. Wallace, S. Benn, H. Schmidt, and I. Tegeder Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats Eur J Neurosci 27 2008 937 946 (Pubitemid 351365176)
-
(2008)
European Journal of Neuroscience
, vol.27
, Issue.4
, pp. 937-946
-
-
Mills, C.1
Makwana, M.2
Wallace, A.3
Benn, S.4
Schmidt, H.5
Tegeder, I.6
Costigan, M.7
Brown Jr., R.H.8
Raivich, G.9
Woolf, C.J.10
-
362
-
-
38149109254
-
Mass spectrometry-based survey of age-associated protein carbonylation in rat brain mitochondria
-
L. Prokai, L.-J. Yan, J.L. Vera-Serrano, S.M. Stevens Jr., and M.J. Forster Mass spectrometry-based survey of age-associated protein carbonylation in rat brain mitochondria J Mass Spectrom 42 2007 1583 1589
-
(2007)
J Mass Spectrom
, vol.42
, pp. 1583-1589
-
-
Prokai, L.1
Yan, L.-J.2
Vera-Serrano, J.L.3
Stevens Jr., S.M.4
Forster, M.J.5
-
363
-
-
0035913190
-
The adenine nucleotide translocator: A target of nitric oxide, peroxynitrite, and 4-hydroxynonenal
-
DOI 10.1038/sj.onc.1204575
-
H.L.A. Vieira, A.-S. Belzacq, D. Haouzu, F. Bernassola, I. Cohen, and E. Jacotot The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal Oncogene 20 2001 4305 4316 (Pubitemid 32726872)
-
(2001)
Oncogene
, vol.20
, Issue.32
, pp. 4305-4316
-
-
Vieira, H.L.A.1
Belzacq, A.-S.2
Haouzi, D.3
Bernassola, F.4
Cohen, I.5
Jacotot, E.6
Ferri, K.F.7
El Hamel, C.8
Bartle, L.M.9
Melino, G.10
Brenner, C.11
Goldmacher, V.12
Kroemer, G.13
-
364
-
-
0037109064
-
Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore
-
DOI 10.1042/BJ20011672
-
G.P. McStay, S.J. Clarke, and A.P. Halestrap Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore Biochem J 367 2002 541 548 (Pubitemid 35216831)
-
(2002)
Biochemical Journal
, vol.367
, Issue.2
, pp. 541-548
-
-
McStay, G.P.1
Clarke, S.J.2
Halestrap, A.P.3
-
365
-
-
66749175710
-
A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis
-
K.A. Trumbull, and J.S. Beckman A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis Antioxid Redox Signal 11 2009 1627 1639
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 1627-1639
-
-
Trumbull, K.A.1
Beckman, J.S.2
-
366
-
-
0034642510
-
Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis
-
P. Costantini, A.-S. Belzacq, H.L.A. Vieira, N. Larochette, M.A. de Pablo, and N. Zamzami Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis Oncogene 19 2000 307 314 (Pubitemid 30077228)
-
(2000)
Oncogene
, vol.19
, Issue.2
, pp. 307-314
-
-
Costantini, P.1
Belzacq, A.-S.2
Vieira, H.L.A.3
Larochette, N.4
De Pablo, M.A.5
Zamzami, N.6
Susin, S.A.7
Brenner, C.8
Kroemer, G.9
-
367
-
-
34249710319
-
Copper induces permeability transition through its interaction with the adenine nucleotide translocase
-
DOI 10.1016/j.cellbi.2007.02.003, PII S1065699507000571
-
N. García, E. Martínez-Abundis, N. Pavón, F. Correa, and E. Chávez Copper induces permeability transition through its interaction with the adenine nucleotide translocase Cell Biol Int 31 2007 893 899 (Pubitemid 46830899)
-
(2007)
Cell Biology International
, vol.31
, Issue.9
, pp. 893-899
-
-
Garcia, N.1
Martinez-Abundis, E.2
Pavon, N.3
Correa, F.4
Chavez, E.5
-
368
-
-
34247540380
-
The permeability transition pore in cell death
-
DOI 10.1007/s10495-007-0747-3, Special Issue on Mitochondria in Apoptosis
-
S. Grimm, and D. Brdiczka The permeability transition pore in cell death Apoptosis 12 2007 841 855 (Pubitemid 46653295)
-
(2007)
Apoptosis
, vol.12
, Issue.5
, pp. 841-855
-
-
Grimm, S.1
Brdiczka, D.2
-
369
-
-
34250679389
-
Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis
-
DOI 10.1073/pnas.0702228104
-
M. Forte, B.G. Gold, G. Marracci, P. Chaudhary, E. Basso, and D. Johnsen Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis Proc Natl Acad Sci USA 104 2007 7558 7563 (Pubitemid 47185945)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.18
, pp. 7558-7563
-
-
Forte, M.1
Gold, B.G.2
Marracci, G.3
Chaudhary, P.4
Basso, E.5
Johnsen, D.6
Yu, X.7
Fowlkes, J.8
Bernardi, P.9
Bourdette, D.10
-
370
-
-
24744460273
-
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
-
DOI 10.1073/pnas.0505294102
-
A.C. Schinzel, O. Takeuchi, Z. Huang, J.K. Fisher, Z. Zhou, and J. Rubens Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia Proc Natl Acad Sci USA 102 2005 12005 12010 (Pubitemid 41291119)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.34
, pp. 12005-12010
-
-
Schinzel, A.C.1
Takeuchi, O.2
Huang, Z.3
Fisher, J.K.4
Zhou, Z.5
Rubens, J.6
Hetz, C.7
Danial, N.N.8
Moskowitz, M.A.9
Korsmeyer, S.J.10
-
371
-
-
36148960127
-
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: A phase III randomised trial
-
DOI 10.1016/S1474-4422(07)70270-3, PII S1474442207702703
-
P.H. Gordon, D.H. Moore, R.G. Miller, J.M. Florence, J.L. Verheijde, and C. Doorish Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomized trial Lancet Neurol 6 2007 1045 1053 (Pubitemid 350116691)
-
(2007)
Lancet Neurology
, vol.6
, Issue.12
, pp. 1045-1053
-
-
Gordon, P.H.1
Moore, D.H.2
Miller, R.G.3
Florence, J.M.4
Verheijde, J.L.5
Doorish, C.6
Hilton, J.F.7
Spitalny, G.M.8
MacArthur, R.B.9
Mitsumoto, H.10
Neville, H.E.11
Boylan, K.12
Mozaffar, T.13
Belsh, J.M.14
Ravits, J.15
Bedlack, R.S.16
Graves, M.C.17
McCluskey, L.F.18
Barohn, R.J.19
Tandan, R.20
more..
-
372
-
-
45749135862
-
Sequencing analysis of OMI/HTRA2 shows previously reported pathogenic mutations in neurologically normal controls
-
DOI 10.1093/hmg/ddn096
-
J. Simon-Sanchez, and A.B. Singleton Sequencing analysis of OMI/HTRA2 shows previously reported pathogenic mutations in neurologically normal controls Hum Mol Genet 17 2008 1988 1993 (Pubitemid 351865847)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.13
, pp. 1988-1993
-
-
Simon-Sanchez, J.1
Singleton, A.B.2
-
373
-
-
77957347060
-
α-Synulcein promotes SNARE-complex assembly in vivo and in vitro
-
J. Burré, M. Sharma, T. Tsetsenis, V. Buchman, M. Etherton, and T.C. Sudhof α-Synulcein promotes SNARE-complex assembly in vivo and in vitro Science 329 5999 2010 1663 1667
-
(2010)
Science
, vol.329
, Issue.5999
, pp. 1663-1667
-
-
Burré, J.1
Sharma, M.2
Tsetsenis, T.3
Buchman, V.4
Etherton, M.5
Sudhof, T.C.6
-
374
-
-
77954379317
-
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease
-
P. Garcia-Reitbock, O. Anichtchik, A. Bellucci, M. Iovino, C. Ballini, E. Fineberg, and B. Ghetti SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease Brain 133 2010 2032 2044
-
(2010)
Brain
, vol.133
, pp. 2032-2044
-
-
Garcia-Reitbock, P.1
Anichtchik, O.2
Bellucci, A.3
Iovino, M.4
Ballini, C.5
Fineberg, E.6
Ghetti, B.7
|