Import and processing of heart mitochondrial cyclophilin D

European Journal of Biochemistry

Volumn 263, Issue 2, 1999, Pages 353-359

  Johnson, Nicholas ^a   Khan, Ayesha ^a   Virji, Sukaina ^a   Ward, John M ^a   Crompton, Martin ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cyclophilins; Import; Mitochondria; Polymerase chain reaction

Indexed keywords

CYCLOPHILIN; CYCLOPHILIN D; CYCLOSPORIN A; DIGITONIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; ENZYME BINDING; HEART MITOCHONDRION; MALE; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; RAT;

ANIMALS; CYCLOPHILINS; DIGITONIN; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMUNOPHILINS; MALE; MITOCHONDRIA, HEART; MODELS, BIOLOGICAL; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; MAMMALIA;

EID: 0033565965     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00490.x     Document Type: Article

References (43)

1. 1. Trandinh, C.C., Pao, G.M. & Saier, M.H. Jr (1992) Structural and evolutionary relationships among the immunophilins: two ubiquitous families of peptidyl-prolyl cis-trans isomerases. FASEB J. 6, 3410-3420.
2. 2. Galat, A. (1993) Peptidyl cis-trans-isomerases: immunophilins. Eur. J. Biochem. 216, 689-707.
3. 3. Handschummacher, R.E., Harding, M.W., Rice, J., Drugge, R.J. & Speicher, D.W. (1984) Cyclophilin: a specific cytosolic binding protein for CSA. Science 226, 544-547.
4. 4. Tropschug, M., Nicholson, D.W., Hartl, F.-U., Kohler, H., Pfanner, N., Wachter, E. & Neupert, W. (1988) Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa. J. Biol. Chem. 263, 14433-14440.
5. 5. McLaughlin, M.M., Bossard, M.J., Koser, P.L., Cafferkey, R., Morris, R.A., Miles, L.M., Stickler, L.M., Bergsma, D.J., Levy, M.A. & Livi, G.P. (1992) The yeast cyclophilin multigene family: purification, cloning and characterisation of a new isoform. Gene 111, 85-92.
6. 6. Bergsma, D.J., Eder, C., Gross, M., Kersten, H., Sylvester, D., Appelbaum, E., Cusimano, D., Livi, G.P., McLaughlin, M.M., Kasyan, K., Porter, T.G., Silverman, C., Dunnington, D., Hand, A., Pritchett, W.P., Bossard, M.J., Brandt, M. & Levy, M.A. (1991) The cyclophilin multigene family of peptidyl-prolyl isomerases. J. Biol. Chem. 266, 23204-23214.
7. 7. Connern, C.P. & Halestrap, A.P. (1992) Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin. Biochem. J. 284, 381-385.
8. 2+-activated inner membrane pore of heart mitochondria. Eur. J. Biochem. 230, 1125-1132.
9. 9. Lodish, H.F. & Kong, N. (1991) Cyclosporin A inhibits an initial step in folding of transferrin within the endoplasmic reticulum. J. Biol. Chem. 266, 14835-14838.
10. 10. Matouschek, A., Rospert, S., Schmid, K., Glick, B.S. & Schatz, G. (1995) Cyclophiln catalyses protein folding in yeast mitochondria. Proc. Natl Acad. Sci. USA 92, 6319-6323.
11. 11. Rassow, J., Mohrs, K., Koidl, S., Barthelmess, I.B., Pfanner, N. & Tropschug, M. (1995) Cyclophilin 20 is involved in mitochondrial protein folding in cooperation with molecular chaperones Hsp70 and Hsp60. Mol. Cell. Biol. 15, 2654-2662.
12. 2+ dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress. Biochem. J. 25, 357-360.
13. 13. Hunter, D.R., Haworth, R.A. & Southard, J.H. (1976) Relationship between configuration, function and permeability in calcium-treated mitochondria. J. Biol. Chem. 251, 5069-5077.
14. 2+-induced membrane transition in mitochondria. Arch. Biochem. 195, 453-459.
15. 15. Nazareth, W., Yafei, N. & Crompton, M. (1991) Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A. J. Mol. Cell. Cardiol. 23, 1351-1354.
16. 2+ uniporter. Biochem. J. 302, 181-185.
17. 17. Griffiths, E.J. & Halestrap, A.P. (1995) Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion. Biochem. J. 307, 93-98.
18. 18. Nieminen, A.-L., Saylor, A.K., Tesfai, S.A., Herman, B. & LeMasters, J.J. (1995) Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. Biochem. J. 307, 99-106.
19. 19. Marchetti, P., Castedo, M., Susin, S.A., Zamzami, N., Hirsch, T., Macho, A., Haeffner, A., Hirsch, F., Geuskens, M. & Koemer, G. (1996) Mitochondrial permeability transition is a central coordinating event of apoptosis. J. Exp. Med. 184, 1156-1160.
20. 20. Le Quoc, K. & Le Quoc, D. (1988) Involvement of the ADP/ATP carrier in calcium-induced perturbations of the mitochondrial inner membrane permeability: importance of the orientation of the nucleotide binding site. Arch. Biochem. Biophys. 265, 249-257.
21. 21. Zoratti, M. & Szabo, I. (1995) The mitochondrial permeability transition. Biochim. Biophys. Acta 1241, 139-176.
22. 22. Beutner, G., Ruck, A., Riede, B., Welte, W. & Brdiczka, D. (1996) Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore. FEBS Lett. 396, 189-195.
23. 23. Beutner, G., Ruck, A., Riede, B. & Brdiczka, D. (1998) Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases. Biochim. Biophys. Acta 1368, 7-18.
24. 24. Crompton, M., Virji, S. & Ward, J.M. (1998) Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore. Eur. J. Biochem. 258, 729-735.
25. 25. Woodfield, K., Ruck, A., Brdiczka, D. & Halestrap, A.P. (1998) Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition. Biochem. J. 336, 287-290.
26. 2+ and oxidant stress. Eur. J. Biochem. 238, 166-172.
27. 27. Isaya, G., Kalousek, F., Fenton, W.A. & Rosenberg, L.E. (1991) Cleavage of precursors by the mitochondrial processing peptidase requires a compatible mature protein or an intermediate octapeptide. J. Cell. Biol. 113, 65-76.
28. 28. Woodfield, K.-Y., Price, N. & Halestrap, A.P. (1997) cDNA cloning of rat mitochondrial cyclophilin. Biochim. Biophys. Acta 1351, 27-30.
29. 29. Hendrick, J.P., Hodges, P.E. & Rosenberg, L.E. (1989) Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: leader peptides cleaved by two matrix proteases share a three-amino acid motif. Proc. Natl Acad. Sci. USA 86, 4056-4060.
30. 30. Pederson, P.L., Greenwalt, J.W., Reynafarje, B., Hullihen, J., Decker, G.L., Soper, J.W. & Bustamente, E. (1979) Preparation and characterisation of mitochondria and submitochondrial particles of rat liver and liver-derived tissues. Methods Cell Biol. 20, 411-481.
31. 31. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
32. 32. Endo, T. & Schatz, G. (1988) Latent membrane perturbation activity of a mitochondrial precursor is exposed by unfolding. EMBO J. 7, 1153-1158.
33. 33. Martemyanov, K.A., Spirin, A.S. & Gudkov, A.T. (1997) Direct expression of PCR products in a cell-free transcription/translation system: synthesis of antibacterial peptide cecropin. FEBS Lett. 414, 268-270.
34. 34. Kozak, M. (1986) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44, 283-292.
35. 35. Craig, D., Howell, M.T., Gibbs, C.L., Hunt, T. & Jackson, R.J. (1992) Plasmid cDNA-directed protein synthesis in a coupled eukaryotic in vitro transcription-translation system. Nucleic Acids Res. 20, 4987-4995.
36. 36. Neupert, W. (1997) Protein import into mitochondria. Annu. Rev. Biochem. 66, 863-917.
37. 37. Nicolli, A., Basso, E., Petronilli, V., Wenger, R.M. & Bernardi, P. (1996) Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, a cyclosporin A-sensitive channel. J. Biol. Chem. 271, 2185-2192.
38. 38. Zuurendonk, P.F., Tischler, M.E., Akerboom, T.P.M., Van Der Meer, R., Williamson, J.R. & Tager, J.M. (1979) Rapid separation of particulate and soluble fractions from isolated cell preparations (digitonin and cell cavitation procedures). Methods Enzymol. 56, 207-223.
39. 39. Kieffer, L.J., Seng, T.W., Li, W., Osterman, D.G., Handschummacher, R.E. & Bayney, R.M. (1993) Cyclophilin 40 a protein with homology to the P59 component of the steroid receptor complex. Cloning of the cDNA and further characterisation. J. Biol. Chem. 268, 12303-12310.
40. 40. Price, E.R., Zydowsky, L.D., Jin, M.J., Baker, C.H., McKeon, F.D. & Walsh, C.T. (1991) Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence. Proc. Natl Acad. Sci. USA 88, 1903-1907.
41. 41. Schneider, H., Chora, N., Schmitz, R., Wehrli, S., Mikol, V., Zurinin, M.G.N., Quesniaux, V.F.J. & Movva, N.R. (1994) Human cyclophilin C: primary structure, tissue distribution and determination of binding specificity for cyclosporins. Biochemistry 33, 8218-8224.
42. 42. Mi, H., Kops, O., Zimmerman, E., Jaschke, A. & Tropschug, M. (1996) A nuclear RNA-binding cyclophilin in T cells. FEBS Lett. 398, 201-205.
43. 43. Marzo, I., Brenner, C., Zamzami, N., Jurgensmeier, J.M., Susin, S.S., Vieira, H.L.A., Prevost, M.-C., Xie, Z., Matsuyama, S., Reed, J.C. & Kroemer, G. (1998) Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281, 2027-2031.