Novel PINK1 mutations in early-onset parkinsonism

Annals of Neurology

Volumn 56, Issue 3, 2004, Pages 424-427

  Hatano, Yasuko ^a   Li, Yuanzhe ^a   Sato, Kenichi ^a   Asakawa, Shuichi ^b   Yamamura, Yasuhiro ^c   Tomiyama, Hiroyuki ^a   Yoshino, Hiroyo ^a   Asahina, Masato ^d   Kobayashi, Susumu ^e   Hassin Baer, Sharon ^f   Lu, Chin Song ^g   Ng, Arlene R ^h   Rosales, Raymond L ⁱ   Shimizu, Nobuyoshi ^b   Toda, Tatsushi ^j,k   Mizuno, Yoshikuni ^a   Hattori, Nobutaka ^a,k  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^d CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e Kitano Hospital   (Japan)

^f SHEBA MEDICAL CENTER   (Israel)

^g CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^h KAGOSHIMA UNIVERSITY   (Japan)

ⁱ Dept of Neurology and Psychiatry   (Philippines)

^j OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^k JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

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Author keywords

[No Author keywords available]

Indexed keywords

LEVODOPA;

ADULT; ARTICLE; BINDING SITE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; HAPLOTYPE; HUMAN; MARKER GENE; ONSET AGE; PARK6 GENE; PARKIN GENE; PARKINSONISM; PINK1 GENE; PRIORITY JOURNAL; RECESSIVE INHERITANCE;

ADOLESCENT; ADULT; AGE OF ONSET; AMINO ACID SEQUENCE; FEMALE; HUMANS; LINKAGE (GENETICS); MALE; MOLECULAR SEQUENCE DATA; MUTATION; PARKINSONIAN DISORDERS; PEDIGREE; PROTEIN KINASES;

EID: 4444237208     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.20251     Document Type: Article

References (7)

1. Lücking CB, Dürr A, Bonifati V, et al. Association between early-onset Parkinson's disease and mutations in the parkin gene. N Engl J Med 2000;342:1560-1567.
2. Bonifati V, Rizzu P, van Baren M, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset Parkinsonism. Science 2003;299:256-259.
3. Hedrich K, Djarmad A, Schäfer N, et al. DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease. Neurology 2004;62:389-394.
4. Valente EM, Abou-Sleiman PM, Caputo V, et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 2004;304:1158-1160.
5. Hatano Y, Sato K, Elibol B, et al. PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations. Neurology (in press).
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7. Jenner P. Oxidative stress in Parkinson's disease. Ann Neurol 2003;53:S26-S38.