The mitochondrial voltage-dependent anion channel (VDAC) as a therapeutic target for initiating cell death

Current Medicinal Chemistry

Volumn 10, Issue 16, 2003, Pages 1527-1533

  Granville, David J ^a,b   Gottlieb, Roberta A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Apoptosis; Bax; Bcl 2; Cell death; Cytochrome c; Heart; Mitochondria; VDAC

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANION; ANION CHANNEL; APOPTOSIS INDUCING FACTOR; APOPTOSIS INHIBITOR; BACTERIAL PROTEIN; CALCIUM; CALCIUM ION; CARDIOLIPIN; CASPASE 3; CASPASE 7; CYTOCHROME C; ETOPOSIDE; GELSOLIN; PACLITAXEL; PORIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN INHIBITOR; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; VIRUS PROTEIN; VOLTAGE GATED CHANNEL FORMING PROTEIN;

APOPTOSIS; CALCIUM CELL LEVEL; CELL ACTIVITY; CHANNEL GATING; CYTOKINE RELEASE; DRUG MECHANISM; DRUG TARGETING; ENZYME RELEASE; HYPERPOLARIZATION; HYPOTHESIS; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; REVIEW; SECOND MESSENGER;

EID: 0041810124     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033457214     Document Type: Review

References (64)

1. Marchetti, P.; Castedo, M.; Susin, S.A.; Zamzami, N.; Hirsch, T.; Macho, A.; Haeffner, A.; Hirsch, F.; Geuskens, M.; Kroemer, G. J. Exp. Med., 1996, 184, 1155.
2. Susin, S.A.; Zamzami, N.; Castedo, M.; Hirsch, T.; Marchetti, P.; Macho, A.; Daugas, E.; Geuskens, M.; Kroemer, G. J. Exp. Med, 1996, 184, 1331.
3. Kluck, R.M.; Bossy-Wetzel, E.; Green, D.R.; Newmeyer, D.D. Science, 1997, 275, 1132.
4. Yang, J.; Liu, X.; Bhalla, K.; Kim, C.N.; Ibrado, A.M.; Cai, J.; Peng, T.; Jones, D.P.; Wang, X. Science, 1997, 275, 1129.
5. Zamzami, N.; Kroemer, G. Nat. Rev. Mol. Cell Biol., 2001, 2, 67.
6. Hirsch, T.; Marzo, I.; Kroemer, G. Biosci. Rep., 1997, 17, 67.
7. Green, D.R.; Reed, JC. Science, 1998, 281, 1309.
8. Granville, D.J.; Gottlieb, R.A. The Scientific World JOURNAL, 2002, 2, 1569.
9. Kuwana, T.; Mackey, M.R.; Perkins, G.; Ellisman, M.H.; Latterich, M.; Schneiter, R.; Green, D.R.; Newmeyer, D.D. Cell, 2002, 111, 331.
10. Crompton, M.; Barksby, E.; Johnson, N.; Capano, M. Biochimie, 2002, 84, 143.
11. Tsujimoto, Y.; Shimizu, S. Cell Death Differ., 2000, 7, 1174.
12. Boya, P.; Roques, B.; Kroemer, G. EMBO J., 2001, 20, 4325.
13. Schein, S.J.; Columbini, M.; Finkelstein, A. J. Membr. Biol., 1976, 30, 99.
14. Blachly-Dyson, E.; Forte, M. IUBMB Life, 2001, 52, 113.
15. Gottlob, K.; Majewski, N.; Kennedy, S.; Kandel, E.; Robey, R.B.; Hay, N. Genes Dev., 2001, 15, 1406.
16. Reed, J.C. Oncogene, 1998, 17, 3225.
17. Sugiyama, T.; Shimizu, S.; Matsuoka, Y.; Yoneda, Y.; Tsujimoto, Y. Oncogene, 2002, 21, 4944.
18. Shimizu, S.; Konishi, A.; Kodama, T.; Tsujimoto, Y. Proc. Natl. Acad. Sci. USA, 2000, 97, 3100.
19. Vander, Heiden, M.G.; Chandel, N.S.; Li, X.X.; Schumacker, P.T.; Colombini, M.; Thompson, C.B. Proc. Natl. Acad. Sci. USA, 2000, 97, 4666.
20. Shimizu, S.; Shinohara, Y.; Tsujimoto, Y. Oncogene, 2000, 19, 4309.
21. Shimizu, S.; Ide, T.; Yanagida, T.; Tsujimoto, Y. J. Biol. Chem., 2000, 275, 12321.
22. Vander, Heiden, M.G.; Li, X.X.; Gottleib, E.; Hill, R.B.; Thompson, C.B.; Colombini, M. J. Biol. Chem., 2001, 276, 19414.
23. Harris, M.H.; Thompson, C.B. Cell Death Differ., 2000, 7, 1182.
24. Shimizu, S.; Narita, M.; Tsujimoto, Y. Nature, 1999, 399, 483.
25. Vander, H.M.G.; Chandel, N.S.; Schumacker, P.T.; Thompson, C.B. Mol. Cell, 1999, 3, 159.
26. Priault, M.; Chaudhuri, B.; Clow, A.; Camougrand, N.; Manon, S. Eur. J. Biochem., 1999, 260, 684.
27. Shimizu, S.; Matsuoka, Y.; Shinohara, Y.; Yoneda, Y.; Tsujimoto, Y. J. Cell Biol., 2001, 152, 237.
28. Pastorino, J.G.; Shulga, N.; Hoek, J.B. J. Biol. Chem., 2002, 277, 7610.
29. Bossy-Wetzel, E.; Newmeyer, D.D.; Green, D.R. EMBO J., 1998, 17, 37.
30. Pozzan, T.; Magalhaes, P.; Rizzuto, R. Cell Calcium, 2000, 28, 279.
31. Vandecasteele, G.; Szabadkai, G.; Rizzuto, R. IUBMB Life, 2001, 52, 213.
32. Pacher, P.; Hajnoczky, G. EMBO J., 2001, 20, 4107.
33. Pacher, P.; Csordas, G.; Hajnoczky, G. Biol. Signals Recept., 2001, 10, 200.
34. Csordas, G.; Hajnoczky, G. Cell Calcium, 2001, 29, 249.
35. Porcelli, A.M.; Pinton, P.; Ainscow, E.K.; Chiesa, A.; Rugolo, M.; Rutter, G.A.; Rizzuto, R. Methods Cell Biol., 2001, 65, 353.
36. Rizzuto, R.; Brini, M.; Murgia, M.; Pozzan, T. Science, 1993, 262, 744.
37. Hajnoczky, G.; Robb-Gaspers, L.D.; Seitz, M.B.; Thomas, AP. Cell, 1995, 82, 415.
38. McCormack, J.G.; Halestrap, A.P.; Denton, R.M. Physiol. Rev., 1990, 70, 391.
39. Hajnoczky, G.; Pacher, P.; Lin, X. IUBMB Life, 2001, 52, 237.
40. Gunter, T.E.; Gunter, K.K. IUBMB Life, 2001, 52, 197.
41. Rapizzi, E.; Pinton, P.; Szabadkai, G.; Wieckowski, MR.; Vandecasteele, G.; Baird, G.; Tuft, R.A.; Fogarty, KE.; Rizzuto, R. J. Cell Biol., 2002, 159, 613.
42. Wallace, D.C. Am. J. Med. Genet., 2001, 106, 71.
43. Genova, M.L.; Ventura, B.; Giuliano, G.; Bovina, C.; Formiggini, G.; Parenti, Castelli, G.; Lenaz, G. FEBS Lett, 2001, 505, 364.
44. Vanden, H.TL.; Shao, Z.; Li, C.; Zak, R.; Schumacker, PT.; Becker, LB. Am. J. Physiol., 1996, 270, H1334.
45. Lesnefsky, E.J.; Gudz, T.I.; Migita, C.T.; Ikeda-Saito, M.; Hassan, M.O.; Turkaly, P.J.; Hoppel, CL. Arch. Biochem. Biophys., 2001, 385, 117.
46. Ide, T.; Tsutsui, H.; Hayashidani, S.; Kang, D.; Suematsu, N.; Nakamura, K.; Utsumi, H.; Hamasaki, N.; Takeshita, A. Circ. Res., 2001, 88, 529.
47. Granville, D.J.; McManus, B.M.; Hunt, D.W. Histol. Histopathol., 2001, 16, 309.
48. Vanden, Hoek, T.L.; Becker, L.B.; Shao, Z.; Li, C.; Schumacker, P.T. J. Biol. Chem., 1998, 273, 18092.
49. Chandel, N.S.; McClintock, D.S.; Feliciano, C.E.; Wood, T.M.; Melendez, J.A.; Rodriguez, A.M.; Schumacker, P.T. J. Biol. Chem., 2000, 275, 25130.
50. Paradies, G.; Petrosillo, G.; Pistolese, M.; Ruggiero, FM. FEBS Lett., 2000, 466, 323.
51. Madesh, M.; Hajnoczky, G. J. Cell Biol., 2001, 155, 1003.
52. Han, D.; Antunes, F.; Canali, R.; Rettori, D.; Cadenas, E. J. Biol. Chem., 2002, 12, 12.
53. Koya, R.C.; Fujita, H.; Shimizu, S.; Ohtsu, M.; Takimoto, M.; Tsujimoto, Y.; Kuzumaki, N. J. Biol. Chem., 2000, 275, 15343.
54. Azuma, T.; Koths, K.; Flanagan, L.; Kwiatkowski, D. J. Biol. Chem., 2000, 275, 3761.
55. Kusano, H.; Shimizu, S.; Koya, R.C.; Fujita, H.; Kamada, S.; Kuzumaki, N.; Tsujimoto, Y. Oncogene, 2000, 19, 4807.
56. Massari, P.; Ho, Y.; Wetzler, LM. Proc. Natl. Acad. Sci. USA, 2000, 97, 9070.
57. Muller, A.; Gunther, D.; Dux, F.; Naumann, M.; Meyer, T.F.; Rudel, T. EMBO J., 1999, 18, 339.
58. Muller, A.; Rassow, J.; Grimm, J.; Machuy, N.; Meyer, T.F.; Rudel, T. EMBO J., 2002, 21, 1916.
59. Granville, D.J.; Carthy, C.M.; Yang, D.; Hunt, D.W.; McManus, B.M. Cell Death Differ., 1998, 5, 653.
60. Rahmani, Z.; Huh, K.W.; Lasher, R.; Siddiqui, A. J. Virol., 2000, 74, 2840.
61. Reed, J.C. Curr. Opin. Oncol., 1995, 7, 541.
62. Reed, J.C.; Miyashita, T.; Takayama, S.; Wang, H.G.; Sato, T.; Krajewski, S.; Aime-Sempe, C.; Bodrug, S.; Kitada, S.; Hanada, M. J. Cell. Biochem., 1996, 60, 23.
63. Reed, J.C. Cancer J. Sci. Am., 1998, 4, Suppl. 1, S8.
64. Chen, M.; Won, D.J.; Krajewski, S.; Gottlieb, R.A. J. Biol. Chem., 2002, 277, 29181.