Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy

Journal of Comparative Neurology

Volumn 432, Issue 1, 2001, Pages 35-60

  Liu, Zhiping ^a   Martin, Lee J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amyotrophic lateral sclerosis; Apoptosis; DNA damage; Single cell gel electrophoresis; Spinal cord injury; Superoxide

Indexed keywords

HYDROGEN PEROXIDE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PEROXYNITRITE; SINGLE STRANDED DNA; SUPEROXIDE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL ISOLATION; CELL LOSS; CELL SUSPENSION; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA STRAND BREAKAGE; MALE; MOTONEURON; NERVE CELL DEGENERATION; NERVE FIBER TRANSECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SPINAL CORD VENTRAL HORN;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; COMET ASSAY; DNA; DNA DAMAGE; FUNCTIONAL LATERALITY; HYDROGEN PEROXIDE; MALE; MODELS, NEUROLOGICAL; MOTOR NEURONS; NITRATES; NITRIC OXIDE DONORS; NITROPRUSSIDE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SPINAL CORD; SUPEROXIDES;

EID: 0035953172     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/cne.1087     Document Type: Article

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