IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

EMBO Journal

Volumn 17, Issue 8, 1998, Pages 2215-2223

  Deveraux, Quinn L ^a   Roy, Natalie ^a   Stennicke, Henning R ^a   Van Arsdale, Todd ^c   Zhou, Qiao ^a   Srinivasula, Srinivasa M ^b   Alnemri, Emad S ^b   Salvesen, Guy S ^a   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c AGOURON PHARMACEUTICALS INC   (United States)

Author keywords

Apoptosis; c IAP; Caspase; Cytochrome

Indexed keywords

APOPTOSIS INHIBITOR; CASPASE; CYTOCHROME C; ENZYME INHIBITOR; PROTEINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION;

APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL EXTRACTS; CELL LINE, TRANSFORMED; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROME C GROUP; CYTOSOL; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

HEXAPODA; INTRACISTERNAL A-PARTICLES;

EID: 0032522738     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.8.2215     Document Type: Article

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