A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine

Annual Review of Genetics

Volumn 39, Issue , 2005, Pages 359-407

  Wallace, Douglas C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; Diabetes; Human origins; Mitochondria; Neurodegenerative diseases; Reactive oxygen species

Indexed keywords

REACTIVE OXYGEN METABOLITE;

ADAPTATION; AGING; CALORIC INTAKE; CANCER; DEGENERATIVE DISEASE; DIABETES MELLITUS; DIET RESTRICTION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENCEPHALOMYOPATHY; ENERGY TRANSFER; ENERGY YIELD; EVOLUTION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; HUMAN; LONGEVITY; MIGRATION; MISSENSE MUTATION; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN SYNTHESIS; REVIEW; SOMATIC MUTATION;

AGING; ENERGY METABOLISM; HUMANS; LONGEVITY; METABOLIC DISEASES; MITOCHONDRIA; NEOPLASMS;

EID: 23844558266     PISSN: 00664197     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.genet.39.110304.095751     Document Type: Review

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