Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 16, 2005, Pages 5703-5708

  Beilina, Alexandra ^a   Van Der Brug, Marcel ^a   Ahmad, Rili ^a   Kesavapany, Sashi ^b   Miller, David W ^a   Petsko, Gregory A ^c   Cookson, Mark R ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c BRANDEIS UNIVERSITY   (United States)

Author keywords

Mitochondria; PARK6; Parkinson's disease

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE; PTEN INDUCED PUTATIVE KINASE 1; SERINE; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; GENE MUTATION; IN VITRO STUDY; MAMMAL CELL; MITOCHONDRION; NONHUMAN; PARKINSONISM; PHILIPPINES; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STABILITY;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME STABILITY; HUMANS; MIDDLE AGED; MITOCHONDRIA; MODELS, MOLECULAR; PARKINSONIAN DISORDERS; POINT MUTATION; PROTEIN KINASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS;

EID: 17644365438     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500617102     Document Type: Article

References (29)

1. Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., Yokochi, M., Mizuno, Y. & Shimizu, N. (1998) Nature 392, 605-608.
2. Bonifati, V., Rizzu, P., van Baren, M. J., Schaap, O., Breedveld, G. J., Krieger, E., Dekker, M. C., Squitieri, F., Ibanez, P., Joosse, M., et al. (2003) Science 299, 256-259.
3. Hilker, R., Klein, C., Ghaemi, M., Kis, B., Strotmann, T., Ozelius, L. J., Lenz, O., Vieregge, P., Herholz, K., Heiss, W. D. & Pramstaller, P. P. (2001) Ann. Neurol. 49, 367-376.
4. Broussolle, E., Lucking, C. B., Ginovart, N., Pollak, P., Remy, P. & Durr, A. (2000) Neurology 55, 877-879.
5. Scherfler, C., Khan, N. L., Pavese, N., Eunson, L., Graham, E., Lees, A. J., Quinn, N. P., Wood, N. W., Brooks, D. J. & Piccini, P. P. (2004) Brain 127, 1332-1342.
6. Khan, N. L., Brooks, D. J., Pavese, N., Sweeney, M. G., Wood, N. W., Lees, A. J. & Piccini, P. (2002) Brain 125, 2248-2256.
7. Dekker, M., Bonifati, V., van Swieten, J., Leenders, N., Galjaard, R. J., Snijders, P., Horstink, M., Heutink, P., Oostra, B. & van Duijn, C. (2003) Movement Disorders 18, 751-757.
8. Hering, R., Strauss, K. M., Tao, X., Bauer, A., Woitalla, D., Mietz, E. M., Petrovic, S., Bauer, P., Schaible, W., Muller, T., et al. (2004) Hum. Mutat. 24, 321-329.
9. Cookson, M. R. (2003) Curr. Biol. 13, R522-R524.
10. Cookson, M. R. (2003) Neuron 37, 7-10.
11. Canet-Aviles, R. M., Wilson, M. A., Miller, D. W., Ahmad, R., McLendon, C., Bandyopadhyay, S., Baptista, M. J., Ringe, D., Petsko, G. A. & Cookson, M. R. (2004) Proc. Natl. Acad. Sci. USA 101, 9103-9108.
12. Valente, E. M., Abou-Sleiman, P. M., Caputo, V., Muqit, M. M., Harvey, K., Gispert, S., Ali, Z., Del Turco, D., Bentivoglio, A. R., Healy, D. G., et al. (2004) Science 304, 1158-1160.
13. Hatano, Y., Li, Y., Sato, K., Asakawa, S., Yamamura, Y., Tomiyama, H., Yoshino, H., Asahina, M., Kobayashi, S., Hassin-Baer, S., et al. (2004) Ann. Neurol. 56, 424-427.
14. Healy, D. G., Abou-Sleiman, P. M., Gibson, J. M., Ross, O. A., Jain, S., Gandhi, S., Gosal, D., Muqit, M. M., Wood, N. W. & Lynch, T. (2004) Neurology 63, 1486-1488.
15. Rogaeva, E., Johnson, J., Lang, A. E., Gulick, C., Owinn-Hardy, K., Kawarai, T., Sato, C., Morgan, A., Werner, J., Nussbaum, R., et al. (2004) Arch. Neurol. (Chicago) 61, 1898-1904.
16. Rohe, C. F., Montagna, P., Breedveld, G., Cortelli, P., Oostra, B. A. & Bonifati, V. (2004) Ann. Neurol. (Chicago) 56, 427-431.
17. Bentivoglio, A. R., Cortelli, P., Valente, E. M., Ialongo, T., Ferraris, A., Elia, A., Montagna, P. & Albanese, A. (2001) Movement Disorders 16, 999-1006.
18. Khan, N. L., Valente, E. M., Bentivoglio, A. R., Wood, N. W., Albanese, A., Brooks, D. J. & Piccini, P. (2002) Ann. Neurol. (Chicago) 52, 849-853.
19. Unoki, M. & Nakamura, Y. (2001) Oncogene 20, 4457-4465.
20. Nakajima, A., Kataoka, K., Hong, M., Sakaguchi, M. & Huh, N. H. (2003) Cancer Lett. 201, 195-201.
21. Shen, J. & Cookson, M. R. (2004) Neuron 43, 301-304.
22. Giasson, B. I. (2004) Sci. Aging Knowledge Environ. 2004, pe42.
23. Miller, D. W., Ahmad, R., Hague, S., Baptista, M. J., Canet-Aviles, R., McLendon, C., Carter, D. M., Zhu, P. P., Stadler, J., Chandran, J., et al. (2003) J. Biol. Chem. 278, 36588-36595.
24. Rodriguez, R., Chinea, G., Lopez, N., Pons, T. & Vriend, G. (1998) Comput. Appl. Biosci. 14, 523-528.
25. Baptista, M. J., O'Farrell, C., Daya, S., Ahmad, R., Miller, D. W., Hardy, J., Fairer, M. J. & Cookson, M. R. (2003) J. Neurochem. 85, 957-968.
26. Neupert, W. (1997) Annu. Rev. Biochem. 66, 863-917.
27. Knox, C., Sass, E., Neupert, W. & Pines, O. (1998) J. Biol. Chem. 273, 25587-25593.
28. Robin, M. A., Prabu, S. K., Raza, H., Anandatheerthavarada, H. K. & Avadhani, N. G. (2003) J. Biol. Chem. 278, 18960-18970.
29. Corner, K., Holtorf, E., Odoy, S., Nuscher, B., Yamamoto, A., Regula, J. T., Beyer, K., Haass, C. & Kahle, P. J. (2004) J. Biol. Chem. 279, 6943-6951.