Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis

Journal of Experimental Medicine

Volumn 185, Issue 8, 1997, Pages 1481-1486

  Leist, Marcel ^a   Single, Barbara ^a   Castoldi, Anna F ^a   Kühnle, Simone ^a   Nicotera, Pierluigi ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DNA FRAGMENT; FAS ANTIGEN; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL LEVEL; CELL NUCLEUS; CONTROLLED STUDY; DIAGNOSIS; DNA DEGRADATION; ETIOLOGY; GLYCOLYSIS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; T LYMPHOCYTE;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; CELL DEATH; CELL LINE; CELL NUCLEUS; CYSTEINE ENDOPEPTIDASES; HUMANS; LAMINS; MITOCHONDRIA; NECROSIS; NUCLEAR PROTEINS;

EID: 0030900980     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.8.1481     Document Type: Article

References (28)

1. Wyllie, A.H., J.F. Kerr, and A.R. Currie. 1980. Cell death: the significance of apoptosis. Int. Rev. Cytol. 68:251-306.
2. Shimizu, S., Y. Eguchi, W. Kamiike, Y. Itoh, J. Hasegawa, K. Yamabe, Y. Otsuki, H. Matsuda, and Y. Tsujimoto. 1996. Induction of apoptosis as well as necrosis by hypoxia and predominant prevention of apoptosis by Bcl-2 and Bcl-xL. Cancer Res. 56:2161-2166.
3. Ankarcrona, M., J.M. Dypbukt, E. Bonfoco, B. Zhivotovsky, S. Orrenius, S.A. Lipton, and P. Nicotera. 1995. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15:961-973.
4. Leist, M., F. Gantner, G. Künstle, I. Bohlinger, G. Tiegs, H. Bluethmann, and A. Wendel. 1996. The 55 kD tumor necrosis factor receptor and CD95 independently signal murine hepatocyte apoptosis and subsequent liver failure. Mol. Med. 2:109-124.
5. Leist, M., F. Gantner, I. Bohlinger, G. Tiegs, P.G. Germann, and A. Wendel. 1995. Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am. J. Pathol. 146:1220-1234.
6. Bonfoco, E., D. Krainc, M. Ankarcrona, P. Nicotera, and S.A. Lipton. 1995. Apoptosis and necrosis: two distinct events induced respectively by mild and intense insults with NMDA or nitric oxide/superoxide in cortical cell cultures. Prof. Natl. Acad. Sci. USA. 92:7162-7166.
7. Dypbukt, J.M., M. Ankarcrona, M. Burkitt, A. Sjöholm, K. Ström, S. Orrenius, and P. Nicotera. 1994. Different prooxidant levels stimulate growth, trigger apoptosis or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyandries. J. Biol. Chem. 269:30533-30560.
8. Trauth, B.C., C. Clas, A.M.J. Peters, S. Matzku, P. Möller, W. Falk, K. Debatin, and P.H. Krammer. 1989. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science (Wash. DC). 245:301-305.
9. Yonehara, S., A. Ishii, and M. Yonehara. 1989. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J. Exp. Med. 169:1747-1756.
10. Weil, M., M.D. Jacobson, H.S.R. Coles, T.J. Davies, R.L. Gardner, K.D. Raff, and M.C. Raff. 1996. Constitutive expression of the machinery for programmed cell death. J. Cell. Biol. 133:1053-1059.
11. Jacobson, M.D., and M.C. Raff. 1995. Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA. Nature (Lond.). 374: 814-816.
12. Anel, A., S. Gamen, M.A. Alava, A.-M. Schmitt-Verhulst, A. Pineiro, and J. Naval. 1996. Role of oxidative damage and IL-1beta-converting enzyme-like proteases in Fas-based cytotoxicity exerted by effector T cells. Int. Immunol. 8:1173-1183.
13. Martin, S.J., C.P.M. Reutlingsperger, and D.R. Green. 1996. Annexin V: a specific probe for apoptotic cells. In Techniques in Apoptosis. T.G. Cotter and S.J. Martin, editors. Portland Press, Ltd., London. 107-121.
14. Bergmeyer, H.U. 1984. Methods of Enzymatic Analysis, Vol. 82, 3rd edition. Verlag Chemie, Weinheim, Germany. 607-612.
15. Wyllie, A.H. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature (Lond.). 284:555-556.
16. Leist, M., F. Gantner, I. Bohlinger, P.G. German, G. Tiegs, and A. Wendel. 1994. Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-α requires transcriptional arrest. J. Immunol. 154:1307-1316.
17. Lazebnik, Y.A., A. Takahashi, R.D. Moir, R.D. Goldman, G.G. Poirier, S.H. Kaufmann, and W.C. Earnshaw. 1995. Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc. Natl. Acad. Sci. USA. 92:9042-9046.
18. Oberhammer, F.A., K. Hochegger, G. Fröschl, R. Tiefenbacher, and M. Pavelka. 1994. Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase. J. Cell Biol. 126: 827-837.
19. Muzio, M., A.M. Chinnaiyan, F.C. Kischkel, K. O'Rourke, A. Shevchenko, J. Ni, C. Scaffidi, J.D. Bretz, M. Zhang, R. Gentz, et al. 1996. FLICE, a novel FADD-homologous ICE/ CED-3-like protease. is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell. 85:817-827.
20. Boldin, M.P., T.M. Goncharov, Y.V. Goltsev, and D. Wallach. 1996. Involvement of MACH, a novel MORT1/ FADD-interacting protease. in Fas/APO-1-and TNF receptor-induced cell death. Cell. 85:803-815.
21. Shimizu, S., Y. Eguchi, W. Kamiike, S. Waguri, Y. Uchiyama, H. Matsuda, and Y. Tsujimoto. 1996. Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors. Oncogene. 13:21-29.
22. Shimizu, S., Y. Eguchi, W. Kamiike, S. Waguri, Y. Uchiyama, H. Matsuda, and Y. Tsujimoto. 1996. Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions. Oncogene. 12: 2045-2050.
23. Zhong, L.-T., T. Sarafian, D.J. Kane, A.C. Charles, S.P. Mah, R.H. Edwards, and D.E. Bredesen. 1993. bcl-2 inhibits death of central neural cells induced by multiple agents. Proc. Natl. Acad. Sci. USA. 90:4533-4537.
24. Jacobson, M.D., J.F. Burne, and M.C. Raff. 1994. Programmed cell death and Bcl-2 protection in the absence of a nucleus. EMBO (Eur. Mol. Biol. Organ.) J. 13:1899-1910.
25. Susin, S.A., N. Zamzami, M. Castedo, T. Hirsch, P. Marchetti, A. Macho, E. Daugas, M. Geuskens, and G. Kroemer. 1996. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J. Exp. Med. 184:1331-1341.
26. Zamzami, N., S.A. Susin, P. Marchetti, T. Hirsch, I. Gómez-Monterrey, M. Castedo, and G. Kroemer. 1996. Mitochondrial control of nuclear apoptosis. J. Exp. Med. 183:1533-1544.
27. Richter, C., M. Schweizer, A. Cossarizza, and C. Franceschi. 1996. Control of apoptosis by the cellular ATP level. FEBS Lett. 378:107-110.
28. Li, Y., V.G. Sharov, N. Jiang, C. Zaloga, H.N. Sabbah, and M. Chopp. 1995. Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat. Am. J. Pathol. 146:1045-1051.