The Parkinson's disease DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 24, 2004, Pages 9103-9108

  Canet Avilés, Rosa M ^a   Wilson, Mark A ^b   Miller, David W ^a   Ahmad, Rili ^a   McLendon, Chris ^a   Bandyopadhyay, Sourav ^a   Baptista, Melisa J ^a   Ringe, Dagmar ^b   Petsko, Gregory A ^b   Cookson, Mark R ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; DJ 1 PROTEIN; ISOPROTEIN; MUTANT PROTEIN; PROTEIN; SULFINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ACIDIFICATION; ARTICLE; BRAIN PROTECTION; CELL DEATH; CRYSTALLIZATION; DJ 1 GENE; GENE; GENE LOSS; GENE MUTATION; HUMAN; HUMAN CELL; MITOCHONDRION; NERVE CELL NECROSIS; OXIDATION; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROCESSING;

1-METHYL-4-PHENYLPYRIDINIUM; AMINO ACID SUBSTITUTION; CELL LINE, TUMOR; CYSTEINE; ELECTROSTATICS; HUMANS; INTRACELLULAR MEMBRANES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MODELS, MOLECULAR; NEUROPROTECTIVE AGENTS; NEUROTRANSMITTER AGENTS; ONCOGENE PROTEINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 2942684871     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0402959101     Document Type: Article

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