The CA1 region of the human hippocampus is a hot spot in Alzheimer's disease

Annals of the New York Academy of Sciences

Volumn 908, Issue , 2000, Pages 255-259

  West, M J ^a   Kawas, C H ^b   Martin, L J ^b   Troncoso, J C ^b  

^a AARHUS UNIVERSITY   (Denmark)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ALZHEIMER DISEASE; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MALE; NEUROPATHOLOGY;

EID: 0033930916     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06652.x     Document Type: Conference Paper

References (12)

1. 1. PRICE, D. 1986. New perspectives on Alzheimer's disease. Ann. Rev. Neurosci. 9: 489-512.
2. 2. JELLINGER, K. 1990. Morphology of Alzheimer's disease and related disorders. In Alzheimer's Disease, Epidemiology, Neuropathology, Neurochemistry, and Clinics. K. Maurer, P. Riederer & H. Beckman, Eds. : 61-77. Chapman and Hall. Vienna.
3. 3. MIRRA, S.S., M.N. HART & R.D. TERRY. 1993. Making the diagnosis of Alzheimer's disease. Arch. Pathol. Lab. Med. 117: 132-144.
4. 4. BALL, M.J. 1988. Topographic distribution of neurofibrillary tangles and granulovacuolar degeneration in hippocampal cortex of ageing and demented patients. A quantitative study. Interdisc. Top. Gerontol. 25: 16-37.
5. 5. BRAAK, H. & E. BRAAK. 1991. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 82: 239-259.
6. 6. WEST, M.J. 1993. Regionally specific loss of neurons in the aging hippocampus. Neurobiol. Aging 14: 287-293.
7. 7. WEST, M.J., P.D. COLEMAN, D.G. FLOOD & J.C. TRONCOSO. 1994. Differences in the pattern of hippocampal neuronal loss in normal aging and Alzheimer's disease. Lancet 344: 769-772.
8. 8. MCKHANN, G., D. DRACHMAN, M. FOLSTEIN et al. 1984 Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group. Neurology 42: 939-944.
9. 9. WEST, M.J., L. SLOMIANKA & H.J.G. GUNDERSEN. 1991. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the Optical Fractionator. Anat. Rec. 231: 482-497.
10. 10. WEST, M.J. & H.J.G. GUNDERSEN. 1990. Unbiased stereological estimation of the number of neurons in the human hippocampus. J. Comp. Neurol. 296: 1-22.
11. 11. SIMIC, G., I. KOSTOVIC, B. WINBLAD & N. BOGDANOVIC. 1997. Volume and number of neurons of the human hippocampal formation in normal aging and Alzheimer's disease. J. Comp. Neurol. 379: 482-494.
12. 12. WEST, M.J. 1993. New stereological methods for counting neurons. Neurobiol. Aging 14: 275-285.