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Volumn 30, Issue 10, 2001, Pages 1163-1170

α-synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro

Author keywords

synuclein; Electron spin resonance spectroscopy; Free radicals; Hydrogen peroxide; Hydroxyl radicals; Neurodegeneration; Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; BETA SYNUCLEIN; FREE RADICAL; GAMMA SYNUCLEIN; HYDROGEN PEROXIDE; HYDROXYL RADICAL; UNCLASSIFIED DRUG;

EID: 0035873812     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00513-5     Document Type: Article
Times cited : (181)

References (37)
  • 2
    • 0028277520 scopus 로고
    • Identification of two distinct synucleins from human brain
    • Jakes R., Spillantini M.G., Goedert M. Identification of two distinct synucleins from human brain. FEBS Lett. 345:1994;27-32.
    • (1994) FEBS Lett. , vol.345 , pp. 27-32
    • Jakes, R.1    Spillantini, M.G.2    Goedert, M.3
  • 3
    • 0028985267 scopus 로고
    • The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system
    • Iwai A., Masliah E., Yoshimoto M., Ge N., Flanagan L., de Silva H.A., Kittel A., Saitoh T. The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. Neuron. 14:1995;467-475.
    • (1995) Neuron , vol.14 , pp. 467-475
    • Iwai, A.1    Masliah, E.2    Yoshimoto, M.3    Ge, N.4    Flanagan, L.5    De Silva, H.A.6    Kittel, A.7    Saitoh, T.8
  • 7
    • 0032568534 scopus 로고    scopus 로고
    • α-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies
    • Spillantini M.G., Crowther R.A., Jakes R., Hasegawa M., Goedert M. α-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA. 95:1998;6469-6473.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6469-6473
    • Spillantini, M.G.1    Crowther, R.A.2    Jakes, R.3    Hasegawa, M.4    Goedert, M.5
  • 8
    • 0031787871 scopus 로고    scopus 로고
    • Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease
    • Conway K.A., Harper J.D., Lansbury P.T. Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease. Nat. Med. 4:1998;1318-1320.
    • (1998) Nat. Med. , vol.4 , pp. 1318-1320
    • Conway, K.A.1    Harper, J.D.2    Lansbury, P.T.3
  • 9
    • 0032573289 scopus 로고    scopus 로고
    • Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of α-synuclein protein implicated in Parkinson's disease
    • El-Agnaf O.M.A., Jakes R., Curran M.D., Wallace A. Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of α-synuclein protein implicated in Parkinson's disease. FEBS Lett. 440:1998;67-70.
    • (1998) FEBS Lett. , vol.440 , pp. 67-70
    • El-Agnaf, O.M.A.1    Jakes, R.2    Curran, M.D.3    Wallace, A.4
  • 12
    • 0031761706 scopus 로고    scopus 로고
    • Protein precipitation: A common etiology in neurodegenerative disorders?
    • Kakizuka A. Protein precipitation a common etiology in neurodegenerative disorders? Trends Genet. 14:1998;396-402.
    • (1998) Trends Genet. , vol.14 , pp. 396-402
    • Kakizuka, A.1
  • 13
    • 0033200063 scopus 로고    scopus 로고
    • Protein misfolding, evolution and disease
    • Dobson C.M. Protein misfolding, evolution and disease. Trends Biochem. Sci. 24:1999;329-332.
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 329-332
    • Dobson, C.M.1
  • 17
    • 0033570337 scopus 로고    scopus 로고
    • Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
    • Hartley D.M., Walsh D.M., Ye C.P., Diehl T., Vasquez S., Vassilev P.M., Teplow D.B., Selkoe D.J. Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J. Neurosci. 19:1999;8876-8884.
    • (1999) J. Neurosci. , vol.19 , pp. 8876-8884
    • Hartley, D.M.1    Walsh, D.M.2    Ye, C.P.3    Diehl, T.4    Vasquez, S.5    Vassilev, P.M.6    Teplow, D.B.7    Selkoe, D.J.8
  • 18
    • 0033551440 scopus 로고    scopus 로고
    • Assembly of Aβ amyloid protofibrils: An in vitro model for a possible early event in Alzheimer's disease
    • Harper J.D., Wong S.S., Lieber C.M., Lansbury P.T. Assembly of Aβ amyloid protofibrils an in vitro model for a possible early event in Alzheimer's disease . Biochemistry. 38:1999;8972-8980.
    • (1999) Biochemistry , vol.38 , pp. 8972-8980
    • Harper, J.D.1    Wong, S.S.2    Lieber, C.M.3    Lansbury, P.T.4
  • 20
    • 0032573597 scopus 로고    scopus 로고
    • Aggregates from mutant and wild-type α-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of β-sheet and amyloid-like filaments
    • El-Agnaf O.M.A., Jakes R., Curran M.D., Middleton D., Ingenito R., Bianchi E., Pessi A., Neill D., Wallace A. Aggregates from mutant and wild-type α-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of β-sheet and amyloid-like filaments. FEBS Lett. 440:1998;71-75.
    • (1998) FEBS Lett. , vol.440 , pp. 71-75
    • El-Agnaf, O.M.A.1    Jakes, R.2    Curran, M.D.3    Middleton, D.4    Ingenito, R.5    Bianchi, E.6    Pessi, A.7    Neill, D.8    Wallace, A.9
  • 24
    • 0029119868 scopus 로고
    • Apolipoprotein E increases the fibrillogenic potential of synthetic peptides derived from Alzheimer's, gelsolin and AA amyloids
    • Soto C., Castano E.M., Prelli F., Kumar A., Baumann M. Apolipoprotein E increases the fibrillogenic potential of synthetic peptides derived from Alzheimer's, gelsolin and AA amyloids. FEBS Lett. 371:1995;110-114.
    • (1995) FEBS Lett. , vol.371 , pp. 110-114
    • Soto, C.1    Castano, E.M.2    Prelli, F.3    Kumar, A.4    Baumann, M.5
  • 26
    • 0028873243 scopus 로고
    • Hydroxyl radical generation by coal mine dust: Possible implications to coal workers' pneumoconiosis (CWP)
    • Dalal N.S., Newman J., Pack D., Leonard S., Vallyathan V. Hydroxyl radical generation by coal mine dust possible implications to coal workers' pneumoconiosis (CWP) . Free Radical Biol. Med. 18:1995;11-20.
    • (1995) Free Radical Biol. Med. , vol.18 , pp. 11-20
    • Dalal, N.S.1    Newman, J.2    Pack, D.3    Leonard, S.4    Vallyathan, V.5
  • 27
    • 0033564726 scopus 로고    scopus 로고
    • Copper(II)-induced self-oligomerization of α-synuclein
    • Paik S.R., Shin H.J., Lee J.H., Chang C.S., Kim J. Copper(II)-induced self-oligomerization of α-synuclein. Biochem. J. 340:1999;821-828.
    • (1999) Biochem. J. , vol.340 , pp. 821-828
    • Paik, S.R.1    Shin, H.J.2    Lee, J.H.3    Chang, C.S.4    Kim, J.5
  • 28
    • 0033844944 scopus 로고    scopus 로고
    • Characterization of copper interactions with Alzheimer amyloid β peptides: Identification of an attomolar-affinity copper binding site on amyloid β1-42
    • Atwood C.S., Scarpa R.C., Huang X., Moir R.D., Jones W.D., Fairlie D.P., Tanzi R.E., Bush A.I. Characterization of copper interactions with Alzheimer amyloid β peptides identification of an attomolar-affinity copper binding site on amyloid β1-42 . J. Neurochem. 75:2000;1219-1233.
    • (2000) J. Neurochem. , vol.75 , pp. 1219-1233
    • Atwood, C.S.1    Scarpa, R.C.2    Huang, X.3    Moir, R.D.4    Jones, W.D.5    Fairlie, D.P.6    Tanzi, R.E.7    Bush, A.I.8
  • 31
    • 0031899172 scopus 로고    scopus 로고
    • Oxidative mechanisms in nigral cell death in Parkinson's disease
    • Jenner P. Oxidative mechanisms in nigral cell death in Parkinson's disease. Mov. Disord. 1:1998;24-34.
    • (1998) Mov. Disord. , vol.1 , pp. 24-34
    • Jenner, P.1
  • 32
    • 0031687793 scopus 로고    scopus 로고
    • Understanding cell death in Parkinson's disease
    • Jenner P., Olanow C. Understanding cell death in Parkinson's disease. Ann. Neurol. 44:1998;S72-S84.
    • (1998) Ann. Neurol. , vol.44 , pp. 72-S84
    • Jenner, P.1    Olanow, C.2
  • 33
    • 0030805622 scopus 로고    scopus 로고
    • A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
    • Alam Z., Daniel S.E., Lees A.J., Marsden D.C., Jenner P., Halliwell B. A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J. Neurochem. 69:1997;1326-1329.
    • (1997) J. Neurochem. , vol.69 , pp. 1326-1329
    • Alam, Z.1    Daniel, S.E.2    Lees, A.J.3    Marsden, D.C.4    Jenner, P.5    Halliwell, B.6
  • 34
    • 0030878073 scopus 로고    scopus 로고
    • Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substanta nigra
    • Alam Z., Jenner A., Daniel S.E., Lees A.J., Cairns N., Marsden C.D., Jenner P., Halliwell B. Oxidative DNA damage in the parkinsonian brain an apparent selective increase in 8-hydroxyguanine levels in substanta nigra . J. Neurochem. 69:1997;1196-1203.
    • (1997) J. Neurochem. , vol.69 , pp. 1196-1203
    • Alam, Z.1    Jenner, A.2    Daniel, S.E.3    Lees, A.J.4    Cairns, N.5    Marsden, C.D.6    Jenner, P.7    Halliwell, B.8
  • 37
    • 0033577159 scopus 로고    scopus 로고
    • Oxidative stress induces amyloid-like aggregate formation of NACP/α-synuclein in vitro
    • Hashimoto M., Hsu L.J., Xia Y., Takeda A., Sisk A., Sundsmo M., Masliah E. Oxidative stress induces amyloid-like aggregate formation of NACP/α-synuclein in vitro. Neuroreport. 10:1999;717-721.
    • (1999) Neuroreport , vol.10 , pp. 717-721
    • Hashimoto, M.1    Hsu, L.J.2    Xia, Y.3    Takeda, A.4    Sisk, A.5    Sundsmo, M.6    Masliah, E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.