MDP-induced interleukin-1β processing requires Nod2 and CIAS1/NALP3

Journal of Leukocyte Biology

Volumn 82, Issue 1, 2007, Pages 177-183

  Pan, Qilin ^a   Mathison, John ^a   Fearns, Colleen ^a   Kravchenko, Vladimir V ^a   Correia, Jean Da Silva ^a   Hoffman, Hal M ^b   Kobayashi, Koichi S ^c   Bertin, John ^d,f   Grant, Ethan P ^d,f   Coyle, Anthony J ^d,g   Sutterwala, Fayyaz S ^e   Ogura, Yasunori ^e   Flavell, Richard A ^e   Ulevitch, Richard J ^a,c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d MILLENNIUM PHARMACEUTICALS INC   (United States)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Synta Pharmaceuticals Corp   (United States)

^g MEDIMMUNE   (United States)

Author keywords

Cytokine; Inflammation; NLR; PAMP

Indexed keywords

APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN; CASPASE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CIAS1 PROTEIN; GENE PRODUCT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; MURAMYL DIPEPTIDE; NALP3 PROTEIN; RECEPTOR INTERACTING PROTEIN 2; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; GENE DELETION; GENE INTERACTION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADJUVANTS, IMMUNOLOGIC; ANIMALS; CARRIER PROTEINS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; MICE; MICE, KNOCKOUT; NOD2 SIGNALING ADAPTOR PROTEIN; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES;

BACTERIA (MICROORGANISMS); MUS;

EID: 34347382756     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1006627     Document Type: Article

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