메뉴 건너뛰기




Volumn 3, Issue 1, 2008, Pages

Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CELASTROL; INTERLEUKIN 18; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEASOME; TRITERPENE DERIVATIVE; ATP DEPENDENT 26S PROTEASE; BACTERIAL ANTIGEN; BACTERIAL TOXIN; TRIPTERINE; TRITERPENE;

EID: 38949194974     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001421     Document Type: Article
Times cited : (19)

References (40)
  • 2
    • 0026775916 scopus 로고
    • Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
    • Molloy SS, Bresnahan PA, Leppla SH, Klimpel KR, Thomas G (1992) Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J Biol Chem 267: 16396-16402.
    • (1992) J Biol Chem , vol.267 , pp. 16396-16402
    • Molloy, S.S.1    Bresnahan, P.A.2    Leppla, S.H.3    Klimpel, K.R.4    Thomas, G.5
  • 3
    • 0028018856 scopus 로고
    • Anthrax protective antigen forms oligomers during intoxication of mammalian cells
    • Milne JC, Furlong D, Hanna PC, Wall JS, Collier RJ (1994) Anthrax protective antigen forms oligomers during intoxication of mammalian cells. J Biol Chem 269: 20607-20612.
    • (1994) J Biol Chem , vol.269 , pp. 20607-20612
    • Milne, J.C.1    Furlong, D.2    Hanna, P.C.3    Wall, J.S.4    Collier, R.J.5
  • 4
    • 0037076364 scopus 로고    scopus 로고
    • The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen
    • Mogridge J, Cunningham K, Lacy DB, Mourez M, Collier RJ (2002) The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen. Proc Natl Acad Sci U S A 99. 7045-7048.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 7045-7048
    • Mogridge, J.1    Cunningham, K.2    Lacy, D.B.3    Mourez, M.4    Collier, R.J.5
  • 5
    • 0037415611 scopus 로고    scopus 로고
    • Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process
    • Abrami L, Uu S, Cosson P, Leppla SH, van der Goot FG (2003) Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process. J Cell Biol 160: 321-328.
    • (2003) J Cell Biol , vol.160 , pp. 321-328
    • Abrami, L.1    Uu, S.2    Cosson, P.3    Leppla, S.H.4    van der Goot, F.G.5
  • 6
    • 10044247127 scopus 로고    scopus 로고
    • Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel
    • Zhang S, Finkelstein A, Collier RJ (2004) Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel. Proc Natl Acad Sci U S A 101: 16756-16761.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 16756-16761
    • Zhang, S.1    Finkelstein, A.2    Collier, R.J.3
  • 7
    • 18244414803 scopus 로고    scopus 로고
    • Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor
    • Duesbery NS, Webb CP, Leppla SH, Gordon VM, Klimpel KR, et al. (1998) Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science 280: 734-737.
    • (1998) Science , vol.280 , pp. 734-737
    • Duesbery, N.S.1    Webb, C.P.2    Leppla, S.H.3    Gordon, V.M.4    Klimpel, K.R.5
  • 9
    • 17044378194 scopus 로고    scopus 로고
    • Anthrax lethal toxin blocks MAPK kinase-dependent IL-2 production in CD4+ T cells
    • Fang H, Cordoba-Rodriguez R, Lankford CS, Frucht DM (2005) Anthrax lethal toxin blocks MAPK kinase-dependent IL-2 production in CD4+ T cells. J Immunol 174: 4966-4971.
    • (2005) J Immunol , vol.174 , pp. 4966-4971
    • Fang, H.1    Cordoba-Rodriguez, R.2    Lankford, C.S.3    Frucht, D.M.4
  • 10
    • 13644268542 scopus 로고    scopus 로고
    • Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling
    • Paccani SR, Tortello F, Ghittoni R, Natale M, Muraro L, et al. (2005) Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling. J Exp Med 201: 325-331.
    • (2005) J Exp Med , vol.201 , pp. 325-331
    • Paccani, S.R.1    Tortello, F.2    Ghittoni, R.3    Natale, M.4    Muraro, L.5
  • 11
    • 0042964832 scopus 로고    scopus 로고
    • Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin
    • Agrawal A, Lingappa J, Leppla SH, Agrawal S, Jabbar A, et al. (2003) Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin. Nature 424: 329-334.
    • (2003) Nature , vol.424 , pp. 329-334
    • Agrawal, A.1    Lingappa, J.2    Leppla, S.H.3    Agrawal, S.4    Jabbar, A.5
  • 12
    • 0032755353 scopus 로고    scopus 로고
    • Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/ IFNgamma-induced release of NO and TNFalpha
    • Pellizzari R, Guidi-Rontani C, Vitale G, Mock M, Montecucco C (1999) Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/ IFNgamma-induced release of NO and TNFalpha. FEBS Lett 462: 199-204.
    • (1999) FEBS Lett , vol.462 , pp. 199-204
    • Pellizzari, R.1    Guidi-Rontani, C.2    Vitale, G.3    Mock, M.4    Montecucco, C.5
  • 13
    • 33644820576 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA
    • Batty S, Chow EM, Kassam A, Der SD, Mogridge J (2006) Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA. Cell Microbiol 8: 130-138.
    • (2006) Cell Microbiol , vol.8 , pp. 130-138
    • Batty, S.1    Chow, E.M.2    Kassam, A.3    SD, D.4    Mogridge, J.5
  • 14
    • 2942702104 scopus 로고    scopus 로고
    • High bactericidal efficiency of type iia phospholipase A2 against Bacillus anthracis and inhibition of its secretion by the lethal toxin
    • Gimenez AP, Wu YZ, Paya M, Delclaux C, Touqui L, et al. (2004) High bactericidal efficiency of type iia phospholipase A2 against Bacillus anthracis and inhibition of its secretion by the lethal toxin. J Immmunol 173: 521-530.
    • (2004) J Immmunol , vol.173 , pp. 521-530
    • Gimenez, A.P.1    Wu, Y.Z.2    Paya, M.3    Delclaux, C.4    Touqui, L.5
  • 15
    • 13844318262 scopus 로고    scopus 로고
    • Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin
    • Kassam A, Der SD, Mogridge J (2005) Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin. Cell Microbiol 7: 281-292.
    • (2005) Cell Microbiol , vol.7 , pp. 281-292
    • Kassam, A.1    SD, D.2    Mogridge, J.3
  • 16
    • 33646484203 scopus 로고    scopus 로고
    • Anthrax lethal toxin has direct and potent inhibitory effects on B cell proliferation and immunoglobulin production
    • Fang H, Xu L, Chen TY, Cyr JM, Frucht DM (2006) Anthrax lethal toxin has direct and potent inhibitory effects on B cell proliferation and immunoglobulin production. J Immunol 176: 6155-6161.
    • (2006) J Immunol , vol.176 , pp. 6155-6161
    • Fang, H.1    Xu, L.2    Chen, T.Y.3    Cyr, J.M.4    Frucht, D.M.5
  • 17
    • 33744914838 scopus 로고    scopus 로고
    • Bacillus anthracis Toxins Inhibit: Human Neutrophil NADPH Oxidase Activity
    • Crawford MA, Aylott CV, Bourdeau RW, Bokoch GM (2006) Bacillus anthracis Toxins Inhibit: Human Neutrophil NADPH Oxidase Activity. J Immunol 176: 7557-7565.
    • (2006) J Immunol , vol.176 , pp. 7557-7565
    • Crawford, M.A.1    Aylott, C.V.2    Bourdeau, R.W.3    Bokoch, G.M.4
  • 18
    • 23944507581 scopus 로고    scopus 로고
    • Anthrax lethal toxin paralyzes neutrophil actin-based motility
    • During RL, Li W, Hao B, Koenig JM, Stephens DS, et al. (2005) Anthrax lethal toxin paralyzes neutrophil actin-based motility. J Infect Dis 192: 837-845.
    • (2005) J Infect Dis , vol.192 , pp. 837-845
    • During, R.L.1    Li, W.2    Hao, B.3    Koenig, J.M.4    Stephens, D.S.5
  • 19
    • 0022891493 scopus 로고
    • Macrophages are sensitive to anthrax lethal toxin through an acid-dcpcndcnt process
    • Friedlander AM (1986) Macrophages are sensitive to anthrax lethal toxin through an acid-dcpcndcnt process. J Biol Chem 261: 7123-7126.
    • (1986) J Biol Chem , vol.261 , pp. 7123-7126
    • Friedlander, A.M.1
  • 20
    • 36749009663 scopus 로고    scopus 로고
    • Anthrax lethal toxin-mediated killing of human and murine dendritic cells impairs the adaptive immune response
    • Alileche A, Serfass ER, Muehlbauer SM, Porcelli SA, Brojatsch J (2005) Anthrax lethal toxin-mediated killing of human and murine dendritic cells impairs the adaptive immune response. PLoS Pathog 1: e19.
    • (2005) PLoS Pathog , vol.1
    • Alileche, A.1    Serfass, E.R.2    Muehlbauer, S.M.3    Porcelli, S.A.4    Brojatsch, J.5
  • 21
    • 33644690647 scopus 로고    scopus 로고
    • BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal tokin
    • Abi-Habib RJ, Urieto JO, Liu S, Leppla SH, Duesbery NS, et al. (2005) BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal tokin. Mol Cancer Ther 4: 1303-1310.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1303-1310
    • Abi-Habib, R.J.1    Urieto, J.O.2    Liu, S.3    Leppla, S.H.4    Duesbery, N.S.5
  • 22
    • 0032920029 scopus 로고    scopus 로고
    • Germination of Bacillus anthracis spores within alveolar macrophages
    • Guidi-Rontani C, Weber-Levy M, Labruyere E, Mock M (1999) Germination of Bacillus anthracis spores within alveolar macrophages. Mol Microbiol 31: 9-17.
    • (1999) Mol Microbiol , vol.31 , pp. 9-17
    • Guidi-Rontani, C.1    Weber-Levy, M.2    Labruyere, E.3    Mock, M.4
  • 23
    • 29644437161 scopus 로고    scopus 로고
    • Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection
    • Cote CK, Van Rooijen N, Welkos SL (2006) Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection. Infect Immun 74: 469-480.
    • (2006) Infect Immun , vol.74 , pp. 469-480
    • Cote, C.K.1    Van Rooijen, N.2    Welkos, S.L.3
  • 24
    • 22744450986 scopus 로고    scopus 로고
    • Anthrax toxin receptor 2 mediates Bacillus anthracis killing of macrophages following spore challenge
    • Banks DJ, Barnajian M, Maldonado-Arocho FJ, Sanchez AM, Bradley KA (2005) Anthrax toxin receptor 2 mediates Bacillus anthracis killing of macrophages following spore challenge. Cell Microbiol 7: 1173-1185.
    • (2005) Cell Microbiol , vol.7 , pp. 1173-1185
    • Banks, D.J.1    Barnajian, M.2    Maldonado-Arocho, F.J.3    Sanchez, A.M.4    Bradley, K.A.5
  • 25
    • 31744441475 scopus 로고    scopus 로고
    • Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
    • Boyden ED, Dietrich WF (2006) Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet 38: 240-244.
    • (2006) Nat Genet , vol.38 , pp. 240-244
    • Boyden, E.D.1    Dietrich, W.F.2
  • 26
    • 0037312509 scopus 로고    scopus 로고
    • NALPs: A novel protein family involved in inflammation
    • Tschopp J, Martinon F, Burns K (2003) NALPs: a novel protein family involved in inflammation. Nat Rev Mol Cell Biol 4: 95-104.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 95-104
    • Tschopp, J.1    Martinon, F.2    Burns, K.3
  • 27
    • 34548856780 scopus 로고    scopus 로고
    • Mitochondrial proteins Bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death
    • Ha SD, Ng D, Lamothe J, Valvano MA, Han J, et al. (2007) Mitochondrial proteins Bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death. J Biol Chem 282: 26275-26283.
    • (2007) J Biol Chem , vol.282 , pp. 26275-26283
    • Ha, S.D.1    Ng, D.2    Lamothe, J.3    Valvano, M.A.4    Han, J.5
  • 28
    • 0033056295 scopus 로고    scopus 로고
    • Proteasome activity is required for anthrax lethal toxin to kill macrophages
    • Tang G, Leppla SH (1999) Proteasome activity is required for anthrax lethal toxin to kill macrophages. Infect Immun 67: 3055-3060.
    • (1999) Infect Immun , vol.67 , pp. 3055-3060
    • Tang, G.1    Leppla, S.H.2
  • 29
    • 33645318478 scopus 로고    scopus 로고
    • Mitochondrial impairment is a critical event in anthrax lethal toxin-induced cytolysis of murine macrophages
    • Alileche A, Squires RC, Muehlbauer SM, Lisanti MP, Brojatsch J (2006) Mitochondrial impairment is a critical event in anthrax lethal toxin-induced cytolysis of murine macrophages. Cell Cycle 5: 100-106.
    • (2006) Cell Cycle , vol.5 , pp. 100-106
    • Alileche, A.1    Squires, R.C.2    Muehlbauer, S.M.3    Lisanti, M.P.4    Brojatsch, J.5
  • 30
    • 0142091353 scopus 로고    scopus 로고
    • Salles II, Tucker AE, Voth DE, Ballard JD (2003) Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages. Proc Natl Arad Sci U S A 100: 12426-12431.
    • Salles II, Tucker AE, Voth DE, Ballard JD (2003) Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages. Proc Natl Arad Sci U S A 100: 12426-12431.
  • 32
    • 23844529468 scopus 로고    scopus 로고
    • Celastrol protects against MPTP-and 3-nitropropionic acid-induced neurotoxicity
    • Cleren C, Calingasan NY, Chen J, Beal MF (2005) Celastrol protects against MPTP-and 3-nitropropionic acid-induced neurotoxicity. J Neurochem 94: 995-1004.
    • (2005) J Neurochem , vol.94 , pp. 995-1004
    • Cleren, C.1    Calingasan, N.Y.2    Chen, J.3    Beal, M.F.4
  • 33
    • 33646406554 scopus 로고    scopus 로고
    • Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice
    • Yang H, Chen D, Cui QC, Yuan X, Dou QP (2006) Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice. Cancer Res 66: 4758-4765.
    • (2006) Cancer Res , vol.66 , pp. 4758-4765
    • Yang, H.1    Chen, D.2    Cui, Q.C.3    Yuan, X.4    Dou, Q.P.5
  • 34
    • 33749433916 scopus 로고    scopus 로고
    • Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators
    • Hieronymus H, Lamb J, Ross KN, Peng XP, Clement C, et al. (2006) Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators. Cancer Cell 10: 321-330.
    • (2006) Cancer Cell , vol.10 , pp. 321-330
    • Hieronymus, H.1    Lamb, J.2    Ross, K.N.3    Peng, X.P.4    Clement, C.5
  • 35
    • 6044271376 scopus 로고    scopus 로고
    • Ubistatins inhibit proteasome-dependcnt degradation by binding the ubiquitin chain
    • Verma R, Peters NR, D'Onofrio M, Tochtrop GP, Sakamoto KM, et al. (2004) Ubistatins inhibit proteasome-dependcnt degradation by binding the ubiquitin chain. Science 306: 117-120.
    • (2004) Science , vol.306 , pp. 117-120
    • Verma, R.1    Peters, N.R.2    D'Onofrio, M.3    Tochtrop, G.P.4    Sakamoto, K.M.5
  • 37
    • 27644518292 scopus 로고    scopus 로고
    • Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates
    • Kisselev AF, Goldberg AL (2005) Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates. Methods Enzymol 398: 364-378.
    • (2005) Methods Enzymol , vol.398 , pp. 364-378
    • Kisselev, A.F.1    Goldberg, A.L.2
  • 38
    • 36349019887 scopus 로고    scopus 로고
    • Proteasomes Control Caspase-1 Activation in Anthrax Lethal Toxin-mediated Cell Killing
    • Squires RC, Muehlbauer SM, Brojatsch J (2007) Proteasomes Control Caspase-1 Activation in Anthrax Lethal Toxin-mediated Cell Killing. J Biol Chem 282: 34260-34267.
    • (2007) J Biol Chem , vol.282 , pp. 34260-34267
    • Squires, R.C.1    Muehlbauer, S.M.2    Brojatsch, J.3
  • 39
    • 38049119726 scopus 로고    scopus 로고
    • Wickliffe KE, Leppla SH, Moayeri M (2007) Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasomc. Cell Microbiol;doi: 10.1111/ j.1462-5822. 2007.01044.x.
    • Wickliffe KE, Leppla SH, Moayeri M (2007) Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasomc. Cell Microbiol;doi: 10.1111/ j.1462-5822. 2007.01044.x.
  • 40
    • 33745674468 scopus 로고    scopus 로고
    • Drug discovery in the ubiquitin-proteasome system
    • Nalepa G, Rolfe M, Harper JW (2006) Drug discovery in the ubiquitin-proteasome system. Nat Rev Drug Discov 5: 596-613.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 596-613
    • Nalepa, G.1    Rolfe, M.2    Harper, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.