-
2
-
-
0037066427
-
The danger model: A renewed sense of self
-
P. Matzinger The danger model: a renewed sense of self Science 296 2002 301 305
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
3
-
-
0141998606
-
Molecular identification of a danger signal that alerts the immune system to dying cells
-
Y. Shi Molecular identification of a danger signal that alerts the immune system to dying cells Nature 425 2003 516 521
-
(2003)
Nature
, vol.425
, pp. 516-521
-
-
Shi, Y.1
-
4
-
-
1542380035
-
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
-
J.S. Park Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein J. Biol. Chem. 279 2004 7370 7377
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7370-7377
-
-
Park, J.S.1
-
5
-
-
17144376810
-
High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
-
M.T. Lotze, and K.J. Tracey High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal Nat. Rev. Immunol. 5 2005 331 342
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 331-342
-
-
Lotze, M.T.1
Tracey, K.J.2
-
6
-
-
0034307339
-
The Toll receptor family and microbial recognition
-
R. Medzhitov, and C. Janeway Jr The Toll receptor family and microbial recognition Trends Microbiol. 8 2000 452 456
-
(2000)
Trends Microbiol.
, vol.8
, pp. 452-456
-
-
Medzhitov, R.1
Janeway Jr., C.2
-
7
-
-
0742324857
-
Toll-like receptors and acquired immunity
-
C. Pasare, and R. Medzhitov Toll-like receptors and acquired immunity Semin. Immunol. 16 2004 23 26
-
(2004)
Semin. Immunol.
, vol.16
, pp. 23-26
-
-
Pasare, C.1
Medzhitov, R.2
-
8
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
A. Iwasaki, and R. Medzhitov Toll-like receptor control of the adaptive immune responses Nat. Immunol. 5 2004 987 995
-
(2004)
Nat. Immunol.
, vol.5
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
9
-
-
12444341944
-
Toll-like receptors in innate immunity
-
K. Takeda, and S. Akira Toll-like receptors in innate immunity Int. Immunol. 17 2005 1 14
-
(2005)
Int. Immunol.
, vol.17
, pp. 1-14
-
-
Takeda, K.1
Akira, S.2
-
10
-
-
9244236078
-
A FADD-dependent innate immune mechanism in mammalian cells
-
S. Balachandran A FADD-dependent innate immune mechanism in mammalian cells Nature 432 2004 401 405
-
(2004)
Nature
, vol.432
, pp. 401-405
-
-
Balachandran, S.1
-
11
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
M. Yoneyama The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses Nat. Immunol. 5 2004 730 737
-
(2004)
Nat. Immunol.
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
-
12
-
-
22444432959
-
NOD-LRR proteins: Role in host-microbial interactions and inflammatory disease
-
N. Inohara NOD-LRR proteins: role in host-microbial interactions and inflammatory disease Annu Rev Biochem 2004
-
(2004)
Annu Rev Biochem
-
-
Inohara, N.1
-
13
-
-
19944431742
-
Inherited disorders of human Toll-like receptor signaling: Immunological implications
-
C.L. Ku Inherited disorders of human Toll-like receptor signaling: immunological implications Immunol. Rev. 203 2005 10 20
-
(2005)
Immunol. Rev.
, vol.203
, pp. 10-20
-
-
Ku, C.L.1
-
14
-
-
17644396670
-
CATERPILLER: A novel gene family important in immunity, cell death, and diseases
-
J. Ting, and B. Davis CATERPILLER: a novel gene family important in immunity, cell death, and diseases Annu. Rev. Immunol. 23 2005 387 414
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 387-414
-
-
Ting, J.1
Davis, B.2
-
15
-
-
0037312509
-
NALPs: A novel protein family involved in inflammation
-
J. Tschopp NALPs: a novel protein family involved in inflammation Nat. Rev. Mol. Cell Biol. 4 2003 95 104
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 95-104
-
-
Tschopp, J.1
-
16
-
-
4544341107
-
The PYRIN connection: Novel players in innate immunity and inflammation
-
C. Stehlik, and J.C. Reed The PYRIN connection: novel players in innate immunity and inflammation J. Exp. Med. 200 2004 551 558
-
(2004)
J. Exp. Med.
, vol.200
, pp. 551-558
-
-
Stehlik, C.1
Reed, J.C.2
-
17
-
-
0035895540
-
Apoptotic molecular machinery: Vastly increased complexity in vertebrates revealed by genome comparisons
-
L. Aravind Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons Science 291 2001 1279 1284
-
(2001)
Science
, vol.291
, pp. 1279-1284
-
-
Aravind, L.1
-
18
-
-
3142724031
-
Toll-like receptor signalling
-
S. Akira, and K. Takeda Toll-like receptor signalling Nat. Rev. Immunol. 4 2004 499 511
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
19
-
-
4644247731
-
STAND, a class of P-loop NTPases including animal and plant regulators of programmed cell death: Multiple, complex domain architectures, unusual phyletic patterns, and evolution by horizontal gene transfer
-
D.D. Leipe STAND, a class of P-loop NTPases including animal and plant regulators of programmed cell death: multiple, complex domain architectures, unusual phyletic patterns, and evolution by horizontal gene transfer J. Mol. Biol. 343 2004 1 28
-
(2004)
J. Mol. Biol.
, vol.343
, pp. 1-28
-
-
Leipe, D.D.1
-
20
-
-
2542457495
-
Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
-
F. Martinon, and J. Tschopp Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases Cell 117 2004 561 574
-
(2004)
Cell
, vol.117
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
21
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
D. Acehan Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation Mol. Cell 9 2002 423 432
-
(2002)
Mol. Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
-
23
-
-
4544234467
-
Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes
-
S. Leibund Gut-Landmann Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes Eur. J. Immunol. 34 2004 1513 1525
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1513-1525
-
-
Leibund Gut-Landmann, S.1
-
24
-
-
17244368276
-
Structure of the apoptotic protease-activating factor 1 bound to ADP
-
S.J. Riedl Structure of the apoptotic protease-activating factor 1 bound to ADP Nature 434 2005 926 933
-
(2005)
Nature
, vol.434
, pp. 926-933
-
-
Riedl, S.J.1
-
25
-
-
0035064073
-
The bare lymphocyte syndrome and the regulation of MHC expression
-
W. Reith, and B. Mach The bare lymphocyte syndrome and the regulation of MHC expression Annu. Rev. Immunol. 19 2001 331 373
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 331-373
-
-
Reith, W.1
MacH, B.2
-
26
-
-
0036777167
-
The Arabidopsis RRS1-R disease resistance gene - Uncovering the plant's nucleus as the new battlefield of plant defense?
-
T. Lahaye The Arabidopsis RRS1-R disease resistance gene - uncovering the plant's nucleus as the new battlefield of plant defense? Trends Plant Sci. 7 2002 425 427
-
(2002)
Trends Plant Sci.
, vol.7
, pp. 425-427
-
-
Lahaye, T.1
-
27
-
-
20044375405
-
Single gene effects in mouse models of host: Pathogen interactions
-
A. Fortier Single gene effects in mouse models of host: pathogen interactions J. Leukoc. Biol 2005
-
(2005)
J. Leukoc. Biol
-
-
Fortier, A.1
-
28
-
-
0028896092
-
The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
-
N. Roy The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy Cell 80 1995 167 178
-
(1995)
Cell
, vol.80
, pp. 167-178
-
-
Roy, N.1
-
29
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
J.P. Hugot Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease Nature 411 2001 599 603
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
-
30
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Y. Ogura A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease Nature 411 2001 603 606
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
-
31
-
-
0037452968
-
Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases
-
M. Chamaillard Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases Proc. Natl. Acad. Sci. U. S. A. 100 2003 3455 3460
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 3455-3460
-
-
Chamaillard, M.1
-
32
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
N. Inohara Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease J. Biol. Chem. 278 2003 5509 5512
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
-
33
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
T. Tanabe Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition EMBO J. 23 2004 1587 1597
-
(2004)
EMBO J.
, vol.23
, pp. 1587-1597
-
-
Tanabe, T.1
-
34
-
-
0038624558
-
NODs: Intracellular proteins involved in inflammation and apoptosis
-
N. Inohara, and G. Nunez NODs: intracellular proteins involved in inflammation and apoptosis Nat. Rev. Immunol. 3 2003 371 382
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 371-382
-
-
Inohara, N.1
Nunez, G.2
-
35
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
K.S. Kobayashi Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract Science 307 2005 731 734
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
-
36
-
-
4444253690
-
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
-
T. Watanabe NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses Nat. Immunol. 5 2004 800 808
-
(2004)
Nat. Immunol.
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
-
37
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-κB activity and IL-1β processing
-
S. Maeda Nod2 mutation in Crohn's disease potentiates NF-κB activity and IL-1β processing Science 307 2005 734 738
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
-
38
-
-
0036846291
-
CARD15 mutations in familial granulomatosis syndromes: A study of the original Blau syndrome kindred and other families with large-vessel arteritis and cranial neuropathy
-
X. Wang CARD15 mutations in familial granulomatosis syndromes: a study of the original Blau syndrome kindred and other families with large-vessel arteritis and cranial neuropathy Arthritis Rheum. 46 2002 3041 3045
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 3041-3045
-
-
Wang, X.1
-
39
-
-
17944372335
-
CARD15 mutations in Blau syndrome
-
C. Miceli-Richard CARD15 mutations in Blau syndrome Nat. Genet. 29 2001 19 20
-
(2001)
Nat. Genet.
, vol.29
, pp. 19-20
-
-
Miceli-Richard, C.1
-
40
-
-
19944431022
-
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-κB activation: Common genetic etiology with Blau syndrome
-
N. Kanazawa Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-κB activation: common genetic etiology with Blau syndrome Blood 105 2005 1195 1197
-
(2005)
Blood
, vol.105
, pp. 1195-1197
-
-
Kanazawa, N.1
-
41
-
-
0036892403
-
Genetic clues to understanding periodic fevers, and possible therapies
-
M.F. McDermott Genetic clues to understanding periodic fevers, and possible therapies Trends Mol. Med. 8 2002 550 554
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 550-554
-
-
McDermott, M.F.1
-
42
-
-
1642285783
-
NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
L. Agostini NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder Immunity 20 2004 319 325
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
-
43
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
D.W. Abbott The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO Curr. Biol. 14 2004 2217 2227
-
(2004)
Curr. Biol.
, vol.14
, pp. 2217-2227
-
-
Abbott, D.W.1
-
44
-
-
11144340996
-
Inflammatory diseases: Is ubiquitinated NEMO at the hub?
-
K.A. Burns, and F. Martinon Inflammatory diseases: is ubiquitinated NEMO at the hub? Curr. Biol. 14 2004 R1040 R1042
-
(2004)
Curr. Biol.
, vol.14
-
-
Burns, K.A.1
Martinon, F.2
-
45
-
-
14744299357
-
The RIP kinases: Crucial integrators of cellular stress
-
E. Meylan, and J. Tschopp The RIP kinases: crucial integrators of cellular stress Trends Biochem. Sci. 30 2005 151 159
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 151-159
-
-
Meylan, E.1
Tschopp, J.2
-
46
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
-
F. Martinon The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-β Mol. Cell 10 2002 417 426
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
-
47
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
S. Mariathasan Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf Nature 430 2004 213 218
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
-
48
-
-
7944232105
-
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
-
F. Martinon Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome Curr. Biol. 14 2004 1929 1934
-
(2004)
Curr. Biol.
, vol.14
, pp. 1929-1934
-
-
Martinon, F.1
-
49
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
S.E. Girardin Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection J. Biol. Chem. 278 2003 8869 8872
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
-
50
-
-
13444266131
-
The role of peptidoglycan in pathogenesis
-
I.G. Boneca The role of peptidoglycan in pathogenesis Curr. Opin. Microbiol. 8 2005 46 53
-
(2005)
Curr. Opin. Microbiol.
, vol.8
, pp. 46-53
-
-
Boneca, I.G.1
-
51
-
-
7944220803
-
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition
-
L.H. Travassos Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition EMBO Rep. 5 2004 1000 1006
-
(2004)
EMBO Rep.
, vol.5
, pp. 1000-1006
-
-
Travassos, L.H.1
-
52
-
-
0242581687
-
The immune response of Drosophila
-
J.A. Hoffmann The immune response of Drosophila Nature 426 2003 33 38
-
(2003)
Nature
, vol.426
, pp. 33-38
-
-
Hoffmann, J.A.1
-
53
-
-
1042278906
-
Plant innate immunity - Direct and indirect recognition of general and specific pathogen-associated molecules
-
D.A. Jones, and D. Takemoto Plant innate immunity - direct and indirect recognition of general and specific pathogen-associated molecules Curr. Opin. Immunol. 16 2004 48 62
-
(2004)
Curr. Opin. Immunol.
, vol.16
, pp. 48-62
-
-
Jones, D.A.1
Takemoto, D.2
-
54
-
-
0037390933
-
Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis
-
B.C. Meyers Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis Plant Cell 15 2003 809 834
-
(2003)
Plant Cell
, vol.15
, pp. 809-834
-
-
Meyers, B.C.1
-
55
-
-
0036914733
-
A gain-of-function mutation in an Arabidopsis Toll interleukin1 receptor-nucleotide binding site-leucine-rich repeat type R gene triggers defense responses and results in enhanced disease resistance
-
Y. Shirano A gain-of-function mutation in an Arabidopsis Toll interleukin1 receptor-nucleotide binding site-leucine-rich repeat type R gene triggers defense responses and results in enhanced disease resistance Plant Cell 14 2002 3149 3162
-
(2002)
Plant Cell
, vol.14
, pp. 3149-3162
-
-
Shirano, Y.1
-
56
-
-
0036775380
-
Constitutive gain-of-function mutants in a nucleotide binding site-leucine rich repeat protein encoded at the Rx locus of potato
-
A. Bendahmane Constitutive gain-of-function mutants in a nucleotide binding site-leucine rich repeat protein encoded at the Rx locus of potato Plant J. 32 2002 195 204
-
(2002)
Plant J.
, vol.32
, pp. 195-204
-
-
Bendahmane, A.1
-
57
-
-
0034254266
-
Direct interaction of resistance gene and avirulence gene products confers rice blast resistance
-
Y. Jia Direct interaction of resistance gene and avirulence gene products confers rice blast resistance EMBO J. 19 2000 4004 4014
-
(2000)
EMBO J.
, vol.19
, pp. 4004-4014
-
-
Jia, Y.1
-
58
-
-
0032422882
-
Plant disease-resistance proteins and the gene-for-gene concept
-
E.A. Van der Biezen, and J.D. Jones Plant disease-resistance proteins and the gene-for-gene concept Trends Biochem. Sci. 23 1998 454 456
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 454-456
-
-
Van Der Biezen, E.A.1
Jones, J.D.2
-
59
-
-
0037205304
-
Plant immunity and film Noir: What gumshoe detectives can teach us about plant-pathogen interactions
-
D.S. Schneider Plant immunity and film Noir: what gumshoe detectives can teach us about plant-pathogen interactions Cell 109 2002 537 540
-
(2002)
Cell
, vol.109
, pp. 537-540
-
-
Schneider, D.S.1
-
60
-
-
0037155687
-
RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis
-
D. Mackey RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis Cell 108 2002 743 754
-
(2002)
Cell
, vol.108
, pp. 743-754
-
-
MacKey, D.1
-
61
-
-
0037423306
-
Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance
-
D. Mackey Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance Cell 112 2003 379 389
-
(2003)
Cell
, vol.112
, pp. 379-389
-
-
MacKey, D.1
-
62
-
-
0037423390
-
Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4
-
M.J. Axtell, and B.J. Staskawicz Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4 Cell 112 2003 369 377
-
(2003)
Cell
, vol.112
, pp. 369-377
-
-
Axtell, M.J.1
Staskawicz, B.J.2
-
63
-
-
0037291224
-
Plant defense: One post, multiple guards?!
-
R. Marathe, and S.P. Dinesh-Kumar Plant defense: one post, multiple guards?! Mol. Cell 11 2003 284 286
-
(2003)
Mol. Cell
, vol.11
, pp. 284-286
-
-
Marathe, R.1
Dinesh-Kumar, S.P.2
-
64
-
-
0038056198
-
Plant pathology: Monitoring a pathogen-targeted host protein
-
J. Ellis, and P. Dodds Plant pathology: monitoring a pathogen-targeted host protein Curr. Biol. 13 2003 R400 R402
-
(2003)
Curr. Biol.
, vol.13
-
-
Ellis, J.1
Dodds, P.2
-
65
-
-
0242626505
-
Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2
-
M. Albrecht Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2 FEBS Lett. 554 2003 520 528
-
(2003)
FEBS Lett.
, vol.554
, pp. 520-528
-
-
Albrecht, M.1
|