Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

Nature

Volumn 437, Issue 7062, 2005, Pages 1167-1172

  Meylan, Etienne ^a   Curran, Joseph ^b   Hofmann, Kay ^c   Moradpour, Darius ^d   Binder, Marco ^e   Bartenschlager, Ralf ^e   Tschopp, Jürg ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c Memorec Biotec GmbH   (Germany)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ENZYME INHIBITION; GENES; IMMUNIZATION; RNA; VIRUSES;

ANTIVIRAL RESPONSES; CARDIF; INTERFERON REGULATORY FACTOR 3 (IRF3); TOLL-LIKE RECEPTOR 3 (TLR3);

PROTEINS;

ADAPTOR PROTEIN; BETA INTERFERON; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; PROTEIN CARDIF; RETINOIC ACID DERIVATIVE; SERINE PROTEINASE; UNCLASSIFIED DRUG;

MEDICINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CYTOKINE PRODUCTION; GENE ACTIVATION; GENE OVEREXPRESSION; HEPATITIS C VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN TARGETING; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DEAD-BOX RNA HELICASES; DNA-BINDING PROTEINS; HEPACIVIRUS; HUMANS; I-KAPPA B KINASE; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MICE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RNA HELICASES; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 27144440476     PISSN: 00280836     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/nature04193     Document Type: Article

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