ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 23, 2008, Pages 8067-8072

  Piccini, Alessandra ^a   Carta, Sonia ^a   Tassi, Sara ^a   Lasiglié, Denise ^b   Fossati, Gianluca ^c   Rubartelli, Anna ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c Italfarmaco   (Italy)

Author keywords

Inflammation; Nonclassical secretion; Pathogen associated molecular patterns; Processing

Indexed keywords

ADENOSINE TRIPHOSPHATE; APYRASE; HISTONE DEACETYLASE; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIGAND; PHOSPHOLIPASE A2; POTASSIUM ION; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; RECEPTOR; URIC ACID; ZYMOSAN; ENZYME INHIBITOR; PATTERN RECOGNITION RECEPTOR; POTASSIUM; PURINERGIC P2 RECEPTOR; TOLL LIKE RECEPTOR;

ARTICLE; AUTOCRINE EFFECT; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOPLASM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOREGULATION; INFLAMMATION; MONOCYTE; POTASSIUM TRANSPORT; PRIORITY JOURNAL; RECEPTOR UPREGULATION; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; KINETICS; METABOLISM; PROTEIN PROCESSING; SECRETION;

ADENOSINE TRIPHOSPHATE; AUTOCRINE COMMUNICATION; CELLS, CULTURED; ENZYME INHIBITORS; HISTONE DEACETYLASES; HUMANS; INTERLEUKIN-18; INTERLEUKIN-1BETA; KINETICS; LIGANDS; MONOCYTES; PHOSPHOLIPASES A2; POTASSIUM; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, PATTERN RECOGNITION; RECEPTORS, PURINERGIC P2; TOLL-LIKE RECEPTORS;

EID: 45849102043     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0709684105     Document Type: Article

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