-
1
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH, Currie AR. 1972. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26:239-57
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
3
-
-
0036234468
-
Pathways of apoptosis in lymphocyte development, homeostasis, and disease
-
Rathmell JC, Thompson CB. 2002. Pathways of apoptosis in lymphocyte development, homeostasis, and disease. Cell 109(Suppl.):S97-107
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Rathmell, J.C.1
Thompson, C.B.2
-
4
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson CB. 1995. Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-61
-
(1995)
Science
, vol.267
, pp. 1456-1461
-
-
Thompson, C.B.1
-
5
-
-
0038394624
-
Caspases and apoptosis
-
Salvesen GS. 2002. Caspases and apoptosis. Essays Biochem. 38:9-19
-
(2002)
Essays Biochem
, vol.38
, pp. 9-19
-
-
Salvesen, G.S.1
-
6
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl SJ, Shi Y. 2004. Molecular mechanisms of caspase regulation during apoptosis. Nat. Rev. Mol. Cell Biol. 5:897-907
-
(2004)
Nat. Rev. Mol. Cell Biol
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
7
-
-
0030610362
-
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
-
DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. 1997. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388:548-54
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
DiDonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
8
-
-
0030613551
-
The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
-
Zandi E, Rothwarf DM, Delhase M, Hayakawa M, Karin M. 1997. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell 91:243-52
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
9
-
-
0031586174
-
Identification and characterization of an IκB kinase
-
Regnier CH, Song HY, Gao X, Goeddel DV, Cao Z, Rothe M. 1997. Identification and characterization of an IκB kinase. Cell 90:373-83
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Regnier, C.H.1
Song, H.Y.2
Gao, X.3
Goeddel, D.V.4
Cao, Z.5
Rothe, M.6
-
10
-
-
0034703023
-
The IκB kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component
-
Krappmann D, Hatada EN, Tegethoff S, Li J, Hippel A, et al. 2000. The IκB kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component. J. Biol. Chem. 275:29779-87
-
(2000)
J. Biol. Chem
, vol.275
, pp. 29779-29787
-
-
Krappmann, D.1
Hatada, E.N.2
Tegethoff, S.3
Li, J.4
Hippel, A.5
-
11
-
-
0030613758
-
NF-kB activation: The IkB kinase revealed?
-
Stancovski I, Baltimore D. 1997. NF-kB activation: the IkB kinase revealed? Cell 91:299-302
-
(1997)
Cell
, vol.91
, pp. 299-302
-
-
Stancovski, I.1
Baltimore, D.2
-
12
-
-
0029976817
-
An essential role for NF-κB in preventing TNF-α-induced cell death
-
Beg AA, Baltimore D. 1996. An essential role for NF-κB in preventing TNF-α-induced cell death. Science 274:782-84
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
13
-
-
0030298294
-
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB; activation prevents cell death
-
Liu ZG, Hsu H, Goeddel DV, Karin M. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB; activation prevents cell death. Cell 87:565-76
-
(1996)
Cell
, vol.87
, pp. 565-576
-
-
Liu, Z.G.1
Hsu, H.2
Goeddel, D.V.3
Karin, M.4
-
14
-
-
0030271387
-
NF-κ: Ten years after
-
Baeuerle PA, Baltimore D. 1996. NF-κ: ten years after. Cell 87:13-20
-
(1996)
Cell
, vol.87
, pp. 13-20
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
15
-
-
2542457495
-
Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
-
Martinon F, Tschopp J. 2004. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117:561-74
-
(2004)
Cell
, vol.117
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
16
-
-
19244365798
-
The domains of apoptosis: A genomics perspective
-
Reed JC, Doctor KS, Godzik A. 2004. The domains of apoptosis: a genomics perspective. Sci. STKE 2004:re9
-
(2004)
Sci. STKE
, vol.2004
-
-
Reed, J.C.1
Doctor, K.S.2
Godzik, A.3
-
17
-
-
11144333066
-
Fire and death: The pyrin domain joins the death-domain superfamily
-
Kohl A, Grutter MG. 2004. Fire and death: The pyrin domain joins the death-domain superfamily. C. R. Biol. 327:1077-86
-
(2004)
C. R. Biol
, vol.327
, pp. 1077-1086
-
-
Kohl, A.1
Grutter, M.G.2
-
18
-
-
28444491105
-
Mechanisms of apoptosis through structural biology
-
Yan N, Shi Y. 2005. Mechanisms of apoptosis through structural biology. Annu. Rev. Cell Dev. Biol. 21:35-56
-
(2005)
Annu. Rev. Cell Dev. Biol
, vol.21
, pp. 35-56
-
-
Yan, N.1
Shi, Y.2
-
19
-
-
8544282423
-
Patterns and clusters within the PSM column in TiBS, 1992-2004
-
McEntyre JR, Gibson TJ. 2004. Patterns and clusters within the PSM column in TiBS, 1992-2004. Trends Biochem. Sci. 29:627-33
-
(2004)
Trends Biochem. Sci
, vol.29
, pp. 627-633
-
-
McEntyre, J.R.1
Gibson, T.J.2
-
20
-
-
0030950228
-
Anovel family of viral death effector domaincontaining molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis
-
Hu S, Vincenz C, Buller M, Dixit VM. 1997. Anovel family of viral death effector domaincontaining molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis. J. Biol. Chem. 272:9621-24
-
(1997)
J. Biol. Chem
, vol.272
, pp. 9621-9624
-
-
Hu, S.1
Vincenz, C.2
Buller, M.3
Dixit, V.M.4
-
21
-
-
12644286556
-
Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFRlinduced apoptosis
-
Bertin J, Armstrong RC, Ottilie S, Martin DA, Wang Y, et al. 1997. Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFRlinduced apoptosis. Proc. Natl. Acad. Sci. USA 94:1172-76
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1172-1176
-
-
Bertin, J.1
Armstrong, R.C.2
Ottilie, S.3
Martin, D.A.4
Wang, Y.5
-
22
-
-
0030970013
-
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
-
Thome M, Schneider P, Hofmann K, Fickenscher H, Meinl E, et al. 1997. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 386:517-21
-
(1997)
Nature
, vol.386
, pp. 517-521
-
-
Thome, M.1
Schneider, P.2
Hofmann, K.3
Fickenscher, H.4
Meinl, E.5
-
23
-
-
28844466449
-
A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection
-
Johnston JB, Barrett JW, Nazarian SH, Goodwin M, Ricuttio D, et al. 2005. A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection. Immunity 23:587-98
-
(2005)
Immunity
, vol.23
, pp. 587-598
-
-
Johnston, J.B.1
Barrett, J.W.2
Nazarian, S.H.3
Goodwin, M.4
Ricuttio, D.5
-
24
-
-
0030465072
-
NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain
-
Huang B, Eberstadt M, Olejniczak ET, Meadows RP, Fesik SW. 1996. NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain. Nature 384:638-41
-
(1996)
Nature
, vol.384
, pp. 638-641
-
-
Huang, B.1
Eberstadt, M.2
Olejniczak, E.T.3
Meadows, R.P.4
Fesik, S.W.5
-
25
-
-
0032580153
-
NMR structure and mutagenesis of the FADD (Mort1) death-effector domain
-
Eberstadt M, Huang B, Chen Z, Meadows RP, Ng SC, et al. 1998. NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Nature 392:941-45
-
(1998)
Nature
, vol.392
, pp. 941-945
-
-
Eberstadt, M.1
Huang, B.2
Chen, Z.3
Meadows, R.P.4
Ng, S.C.5
-
26
-
-
0032563323
-
Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment
-
Chou JJ, Matsuo H, Duan H, Wagner G. 1998. Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment. Cell 94:171-80
-
(1998)
Cell
, vol.94
, pp. 171-180
-
-
Chou, J.J.1
Matsuo, H.2
Duan, H.3
Wagner, G.4
-
27
-
-
0141817846
-
NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain
-
Hiller S, Kohl A, Fiorito F, Herrmann T, Wider G, et al. 2003. NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain. Structure 11:1199-205
-
(2003)
Structure
, vol.11
, pp. 1199-1205
-
-
Hiller, S.1
Kohl, A.2
Fiorito, F.3
Herrmann, T.4
Wider, G.5
-
28
-
-
0027211704
-
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: Implications for TNF receptor activation
-
Banner DW, D'Arcy A, Janes W, Gentz R, Schoenfeld HJ, et al. 1993. Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. Cell 73:431-45
-
(1993)
Cell
, vol.73
, pp. 431-445
-
-
Banner, D.W.1
D'Arcy, A.2
Janes, W.3
Gentz, R.4
Schoenfeld, H.J.5
-
29
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, et al. 1995. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14:5579-88
-
(1995)
EMBO J
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
-
30
-
-
0027275490
-
A novel domain within the 55 kd TNF receptor signals cell death
-
Tartaglia LA, Ayres TM, Wong GH, Goeddel DV. 1993. A novel domain within the 55 kd TNF receptor signals cell death. Cell 74:845-53
-
(1993)
Cell
, vol.74
, pp. 845-853
-
-
Tartaglia, L.A.1
Ayres, T.M.2
Wong, G.H.3
Goeddel, D.V.4
-
31
-
-
0027281373
-
A novel protein domain required for apoptosis: Mutational analysis of human Fas antigen
-
Itoh N, Nagata S. 1993. A novel protein domain required for apoptosis: mutational analysis of human Fas antigen. J. Biol. Chem. 268:10932-37
-
(1993)
J. Biol. Chem
, vol.268
, pp. 10932-10937
-
-
Itoh, N.1
Nagata, S.2
-
32
-
-
0037204952
-
The Fas signaling pathway: More than a paradigm
-
Wajant H. 2002. The Fas signaling pathway: more than a paradigm. Science 296:1635-36
-
(2002)
Science
, vol.296
, pp. 1635-1636
-
-
Wajant, H.1
-
33
-
-
0028985261
-
Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects
-
Boldin MP, Mett IL, Varfolomeev EE, Chumakov I, Shemer-Avni Y, et al. 1995. Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects. J. Biol. Chem. 270:387-91
-
(1995)
J. Biol. Chem
, vol.270
, pp. 387-391
-
-
Boldin, M.P.1
Mett, I.L.2
Varfolomeev, E.E.3
Chumakov, I.4
Shemer-Avni, Y.5
-
34
-
-
0029026548
-
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
-
Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81:505-12
-
(1995)
Cell
, vol.81
, pp. 505-512
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Tewari, M.3
Dixit, V.M.4
-
35
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, et al. 1996. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85:817-27
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
-
36
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
-
Boldin MP, Goncharov TM, Goltsev YV, Wallach D. 1996. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85:803-15
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
37
-
-
0033613143
-
Caspase activation: The induced-proximity model
-
Salvesen GS, Dixit VM. 1999. Caspase activation: the induced-proximity model. Proc. Natl. Acad. Sci. USA 96:10964-67
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10964-10967
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
38
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema JP, Scaffidi C, Kischkel FC, Shevchenko A, Mann M, et al. 1997. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16:2794-804
-
(1997)
EMBO J
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
Shevchenko, A.4
Mann, M.5
-
39
-
-
2942746419
-
Caspase activation: Revisiting the induced proximity model
-
Shi Y. 2004. Caspase activation: revisiting the induced proximity model. Cell 117:855-58
-
(2004)
Cell
, vol.117
, pp. 855-858
-
-
Shi, Y.1
-
40
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O, Tschopp J. 2003. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114:181-90
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
41
-
-
0035496099
-
Regulation of lymphocyte proliferation and death by FLIP
-
Thome M, Tschopp J. 2001. Regulation of lymphocyte proliferation and death by FLIP. Nat. Rev. Immunol. 1:50-58
-
(2001)
Nat. Rev. Immunol
, vol.1
, pp. 50-58
-
-
Thome, M.1
Tschopp, J.2
-
42
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature 388:190-95
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
-
43
-
-
0030746740
-
Casper is a FADD- and caspase-related inducer of apoptosis
-
Shu HB, Halpin DR, Goeddel DV. 1997. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity 6:751-63
-
(1997)
Immunity
, vol.6
, pp. 751-763
-
-
Shu, H.B.1
Halpin, D.R.2
Goeddel, D.V.3
-
44
-
-
0030810981
-
FLAME-1, a novel FADD-like antiapoptotic molecule that regulates Fas/TNFR1-induced apoptosis
-
Srinivasula SM, Ahmad M, Ottilie S, Bullrich F, Banks S, et al. 1997. FLAME-1, a novel FADD-like antiapoptotic molecule that regulates Fas/TNFR1-induced apoptosis. J. Biol. Chem. 272:18542-45
-
(1997)
J. Biol. Chem
, vol.272
, pp. 18542-18545
-
-
Srinivasula, S.M.1
Ahmad, M.2
Ottilie, S.3
Bullrich, F.4
Banks, S.5
-
45
-
-
0030961084
-
CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis
-
Inohara N, Koseki T, Hu Y, Chen S, Nunez G. 1997. CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis. Proc. Natl. Acad. Sci. USA 94:10717-22
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10717-10722
-
-
Inohara, N.1
Koseki, T.2
Hu, Y.3
Chen, S.4
Nunez, G.5
-
46
-
-
0030877440
-
CASH, a novel caspase homologue with death effector domains
-
Goltsev YV, Kovalenko AV, Arnold E, Varfolomeev EE, Brodianskii VM, Wallach D. 1997. CASH, a novel caspase homologue with death effector domains. J. Biol. Chem. 272:19641-44
-
(1997)
J. Biol. Chem
, vol.272
, pp. 19641-19644
-
-
Goltsev, Y.V.1
Kovalenko, A.V.2
Arnold, E.3
Varfolomeev, E.E.4
Brodianskii, V.M.5
Wallach, D.6
-
47
-
-
0030758315
-
MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death
-
Han DK, Chaudhary PM, Wright ME, Friedman C, Trask BJ, et al. 1997. MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc. Natl. Acad. Sci. USA 94:11333-38
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11333-11338
-
-
Han, D.K.1
Chaudhary, P.M.2
Wright, M.E.3
Friedman, C.4
Trask, B.J.5
-
48
-
-
0030841911
-
I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
-
Hu S, Vincenz C, Ni J, Gentz R, Dixit VM. 1997. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J. Biol. Chem. 272:17255-57
-
(1997)
J. Biol. Chem
, vol.272
, pp. 17255-17257
-
-
Hu, S.1
Vincenz, C.2
Ni, J.3
Gentz, R.4
Dixit, V.M.5
-
49
-
-
7344220967
-
Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
-
Rasper DM, Vaillancourt JP, Hadano S, Houtzager VM, Seiden I, et al. 1998. Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex. Cell Death Differ. 5:271-88
-
(1998)
Cell Death Differ
, vol.5
, pp. 271-288
-
-
Rasper, D.M.1
Vaillancourt, J.P.2
Hadano, S.3
Houtzager, V.M.4
Seiden, I.5
-
50
-
-
0036139833
-
Binding of FADD and caspase-8 to molluscum contagiosum virus MC159 v-FLIP is not sufficient for its antiapoptotic function
-
Garvey TL, Bertin J, Siegel RM, Wang GH, Lenardo MJ, Cohen JI. 2002. Binding of FADD and caspase-8 to molluscum contagiosum virus MC159 v-FLIP is not sufficient for its antiapoptotic function. J. Virol. 76:697-706
-
(2002)
J. Virol
, vol.76
, pp. 697-706
-
-
Garvey, T.L.1
Bertin, J.2
Siegel, R.M.3
Wang, G.H.4
Lenardo, M.J.5
Cohen, J.I.6
-
51
-
-
0035970321
-
Molluscum contagiosum virus inhibitors of apoptosis: The MC159 v-FLIP protein blocks Fas-induced activation of procaspases and degradation of the related MC160 protein
-
Shisler JL, Moss B. 2001. Molluscum contagiosum virus inhibitors of apoptosis: The MC159 v-FLIP protein blocks Fas-induced activation of procaspases and degradation of the related MC160 protein. Virology 282:14-25
-
(2001)
Virology
, vol.282
, pp. 14-25
-
-
Shisler, J.L.1
Moss, B.2
-
52
-
-
0032975917
-
Sequence and genomic analysis of a Rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8
-
Searles RP, Bergquam EP, Axthelm MK, Wong SW. 1999. Sequence and genomic analysis of a Rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. J. Virol. 73:3040-53
-
(1999)
J. Virol
, vol.73
, pp. 3040-3053
-
-
Searles, R.P.1
Bergquam, E.P.2
Axthelm, M.K.3
Wong, S.W.4
-
53
-
-
1042280346
-
Development of lymphoma in autoimmune lymphoproliferative syndrome (ALPS) and its relationship to Fas gene mutations
-
Poppema S, Maggio E, van den Berg A. 2004. Development of lymphoma in autoimmune lymphoproliferative syndrome (ALPS) and its relationship to Fas gene mutations. Leuk. Lymph. 45:423-31
-
(2004)
Leuk. Lymph
, vol.45
, pp. 423-431
-
-
Poppema, S.1
Maggio, E.2
van den Berg, A.3
-
54
-
-
0037279111
-
Autoimmune lymphoproliferative syndromes: Genetic defects of apoptosis pathways
-
Rieux-Laucat F, Le Deist F, Fischer A. 2003. Autoimmune lymphoproliferative syndromes: genetic defects of apoptosis pathways. Cell Death Differ. 10:124-33
-
(2003)
Cell Death Differ
, vol.10
, pp. 124-133
-
-
Rieux-Laucat, F.1
Le Deist, F.2
Fischer, A.3
-
55
-
-
0029025441
-
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lyphoproliferative syndrome
-
Fisher GH, Rosenberg FJ, Straus SE, Dale JK, Middelton LA, et al. 1995. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lyphoproliferative syndrome. Cell 81:935-46
-
(1995)
Cell
, vol.81
, pp. 935-946
-
-
Fisher, G.H.1
Rosenberg, F.J.2
Straus, S.E.3
Dale, J.K.4
Middelton, L.A.5
-
56
-
-
0030614415
-
Clincal, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis
-
Sneller MC, Wang J, Dale JK, Strober W, Middelton LA, et al. 1997. Clincal, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis. Blood 89:1341-48
-
(1997)
Blood
, vol.89
, pp. 1341-1348
-
-
Sneller, M.C.1
Wang, J.2
Dale, J.K.3
Strober, W.4
Middelton, L.A.5
-
57
-
-
0029006893
-
Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
-
Rieux-Laucat F, Le Deist F, Hivroz C, Roberts IA, Debatin KM, et al. 1995. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268:1347-49
-
(1995)
Science
, vol.268
, pp. 1347-1349
-
-
Rieux-Laucat, F.1
Le Deist, F.2
Hivroz, C.3
Roberts, I.A.4
Debatin, K.M.5
-
58
-
-
6844240196
-
Novel Fas (CD95/APO-1) mutations in infants with a lymphoproliferative disorder
-
Kasahara Y, Wada T, Niida Y, Yachie A, Seki H, et al. 1998. Novel Fas (CD95/APO-1) mutations in infants with a lymphoproliferative disorder. Int. Immunol. 10:195-202
-
(1998)
Int. Immunol
, vol.10
, pp. 195-202
-
-
Kasahara, Y.1
Wada, T.2
Niida, Y.3
Yachie, A.4
Seki, H.5
-
59
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. 1997. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90:405-13
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
60
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, et al. 1997. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-89
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
-
61
-
-
0036899079
-
Apoptosomes: Engines for caspase activation
-
Adams JM, Cory S. 2002. Apoptosomes: engines for caspase activation. Curr. Opin. Cell Biol. 14:715-20
-
(2002)
Curr. Opin. Cell Biol
, vol.14
, pp. 715-720
-
-
Adams, J.M.1
Cory, S.2
-
62
-
-
0028168593
-
Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death
-
Wang L, Miura M, Bergeron L, Zhu H, Yuan J. 1994. Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78:739-50
-
(1994)
Cell
, vol.78
, pp. 739-750
-
-
Wang, L.1
Miura, M.2
Bergeron, L.3
Zhu, H.4
Yuan, J.5
-
63
-
-
2442453730
-
The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress
-
Tinel A, Tschopp J. 2004. The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress. Science 304:843-46
-
(2004)
Science
, vol.304
, pp. 843-846
-
-
Tinel, A.1
Tschopp, J.2
-
64
-
-
26444433872
-
Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD
-
Berube C, Boucher LM, Ma W, Wakeham A, Salmena L, et al. 2005. Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD. Proc. Natl. Acad. Sci. USA 102:14314-20
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14314-14320
-
-
Berube, C.1
Boucher, L.M.2
Ma, W.3
Wakeham, A.4
Salmena, L.5
-
65
-
-
0033812557
-
Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis
-
Lin Y, Ma W, Benchimol S. 2000. Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis. Nat. Genet. 26:122-27
-
(2000)
Nat. Genet
, vol.26
, pp. 122-127
-
-
Lin, Y.1
Ma, W.2
Benchimol, S.3
-
66
-
-
0031021356
-
RAIDD is a new 'death' adaptor molecule
-
Duan H, Dixit VM. 1997. RAIDD is a new 'death' adaptor molecule. Nature 385:86-89
-
(1997)
Nature
, vol.385
, pp. 86-89
-
-
Duan, H.1
Dixit, V.M.2
-
67
-
-
0037162833
-
Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization
-
Lassus P, Opitz-Araya X, Lazebnik Y. 2002. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science 297:1352-54
-
(2002)
Science
, vol.297
, pp. 1352-1354
-
-
Lassus, P.1
Opitz-Araya, X.2
Lazebnik, Y.3
-
68
-
-
28944447430
-
PIDD mediates NF-κB activation in response to DNA damage
-
Janssens S, Tinel A, Lippens S, Tschopp J. 2005. PIDD mediates NF-κB activation in response to DNA damage. Cell 123:1079-92
-
(2005)
Cell
, vol.123
, pp. 1079-1092
-
-
Janssens, S.1
Tinel, A.2
Lippens, S.3
Tschopp, J.4
-
69
-
-
33646899303
-
Sorting out Toll signals
-
Fitzgerald KA, Chen ZJ. 2006. Sorting out Toll signals. Cell 125:834-36
-
(2006)
Cell
, vol.125
, pp. 834-836
-
-
Fitzgerald, K.A.1
Chen, Z.J.2
-
70
-
-
23144449789
-
Ubiquitin signaling in the NF-κB pathway
-
Chen ZJ. 2005. Ubiquitin signaling in the NF-κB pathway. Nat. Cell Biol. 7:758-65
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
72
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. 1996. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86:973-83
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
73
-
-
0026030444
-
Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity
-
Letsou A, Alexander S, Orth K, Wasserman SA. 1991. Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity. Proc. Natl. Acad. Sci. USA 88:810-14
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 810-814
-
-
Letsou, A.1
Alexander, S.2
Orth, K.3
Wasserman, S.A.4
-
74
-
-
2442612540
-
CARMA1, BCL-10 and MALTI in lymphocyte development and activation
-
Thome M. 2004. CARMA1, BCL-10 and MALTI in lymphocyte development and activation. Nat. Rev. Immunol. 4:348-59
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 348-359
-
-
Thome, M.1
-
75
-
-
0035843970
-
Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-κB activation
-
Gaide O, Martinon F, Micheau O, Bonnet D, Thome M, Tschopp J. 2001. Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-κB activation. FEBS Lett. 496:121-27
-
(2001)
FEBS Lett
, vol.496
, pp. 121-127
-
-
Gaide, O.1
Martinon, F.2
Micheau, O.3
Bonnet, D.4
Thome, M.5
Tschopp, J.6
-
76
-
-
0036707522
-
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-κ activation
-
Gaide O, Favier B, Legler DF, Bonnet D, Brissoni B, et al. 2002. CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-κ activation. Nat. Immunol. 3:836-43
-
(2002)
Nat. Immunol
, vol.3
, pp. 836-843
-
-
Gaide, O.1
Favier, B.2
Legler, D.F.3
Bonnet, D.4
Brissoni, B.5
-
77
-
-
0035374349
-
Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-κB signaling pathway
-
Lucas PC, Yonezumi M, Inohara N, McAllister-Lucas LM, Abazeed ME, et al. 2001. Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-κB signaling pathway. J. Biol. Chem. 276:19012-19
-
(2001)
J. Biol. Chem
, vol.276
, pp. 19012-19019
-
-
Lucas, P.C.1
Yonezumi, M.2
Inohara, N.3
McAllister-Lucas, L.M.4
Abazeed, M.E.5
-
78
-
-
0033638182
-
Identification of paracaspases and metacaspases: Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma
-
Uren AG, O'Rourke K, Aravind LA, Pisabarro MT, Seshagiri S, et al. 2000. Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol. Cell 6:961-67
-
(2000)
Mol. Cell
, vol.6
, pp. 961-967
-
-
Uren, A.G.1
O'Rourke, K.2
Aravind, L.A.3
Pisabarro, M.T.4
Seshagiri, S.5
-
79
-
-
33344476184
-
cFLIP regulation of lymphocyte activation and development
-
Budd RC, Yeh WC, Tschopp J. 2006. cFLIP regulation of lymphocyte activation and development. Nat. Rev. Immunol. 6:196-204
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 196-204
-
-
Budd, R.C.1
Yeh, W.C.2
Tschopp, J.3
-
80
-
-
2342629277
-
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
-
Sun L, Deng L, Ea CK, Xia ZP, Chen ZJ. 2004. The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol. Cell 14:289-301
-
(2004)
Mol. Cell
, vol.14
, pp. 289-301
-
-
Sun, L.1
Deng, L.2
Ea, C.K.3
Xia, Z.P.4
Chen, Z.J.5
-
81
-
-
0033591330
-
Nodi, an Apaf-1 -like activator of caspase-9 and nuclear factor-κB
-
Inohara N, Koseki T, del Peso L, Hu Y, Yee C, et al. 1999. Nodi, an Apaf-1 -like activator of caspase-9 and nuclear factor-κB. J. Biol. Chem. 274:14560-67
-
(1999)
J. Biol. Chem
, vol.274
, pp. 14560-14567
-
-
Inohara, N.1
Koseki, T.2
del Peso, L.3
Hu, Y.4
Yee, C.5
-
82
-
-
0032524908
-
RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95 mediated apoptosis
-
Inohara N, del Peso L, Koseki T, Chen S, Nunez G. 1998. RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95 mediated apoptosis. J. Biol. Chem. 273:12296-300
-
(1998)
J. Biol. Chem
, vol.273
, pp. 12296-12300
-
-
Inohara, N.1
del Peso, L.2
Koseki, T.3
Chen, S.4
Nunez, G.5
-
83
-
-
0034623225
-
An induced proximity model for NF-κ activation in the Nod1/RICK and RIP signaling pathways
-
Inohara N, Koseki T, Lin J, del Peso L, Lucas PC, et al. 2000. An induced proximity model for NF-κ activation in the Nod1/RICK and RIP signaling pathways. J. Biol. Chem. 275:27823-31
-
(2000)
J. Biol. Chem
, vol.275
, pp. 27823-27831
-
-
Inohara, N.1
Koseki, T.2
Lin, J.3
del Peso, L.4
Lucas, P.C.5
-
84
-
-
0032537836
-
Identification of CARDIAK, a RIP-like kinase that associates with caspase-1
-
Thome M, Hofmann K, Burns K, Martinon F, Bodmer JL, et al. 1998. Identification of CARDIAK, a RIP-like kinase that associates with caspase-1. Curr. Biol. 8:885-88
-
(1998)
Curr. Biol
, vol.8
, pp. 885-888
-
-
Thome, M.1
Hofmann, K.2
Burns, K.3
Martinon, F.4
Bodmer, J.L.5
-
85
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-κB
-
Ogura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G. 2001. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-κB. J. Biol. Chem. 276:4812-18
-
(2001)
J. Biol. Chem
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
Inohara, N.2
Benito, A.3
Chen, F.F.4
Yamaoka, S.5
Nunez, G.6
-
86
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, et al. 2001. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411:603-6
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
-
87
-
-
0034730325
-
ICEBERG: A novel inhibitor of interleukin-1β generation
-
Humke EW, Shriver SK, Starovasnik MA, Fairbrother WJ, Dixit VM. 2000. ICEBERG: a novel inhibitor of interleukin-1β generation. Cell 103:99-111
-
(2000)
Cell
, vol.103
, pp. 99-111
-
-
Humke, E.W.1
Shriver, S.K.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
88
-
-
0035860780
-
Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing
-
Lee SH, Stehlik C, Reed JC. 2001. Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing. J. Biol. Chem. 276:34495-500
-
(2001)
J. Biol. Chem
, vol.276
, pp. 34495-34500
-
-
Lee, S.H.1
Stehlik, C.2
Reed, J.C.3
-
89
-
-
33746028777
-
Intracellular pattern recognition receptors in the host response
-
Meylan E, Tschopp J, Karin M. 2006. Intracellular pattern recognition receptors in the host response. Nature 442:39-44
-
(2006)
Nature
, vol.442
, pp. 39-44
-
-
Meylan, E.1
Tschopp, J.2
Karin, M.3
-
90
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ. 2005. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF 3. Cell 122:669-82
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
91
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, et al. 2005. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437:1167-72
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
-
92
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai T, Takahashi K, Sato S, Coban C, Kumar H, et al. 2005. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6:981-88
-
(2005)
Nat. Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
-
93
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-β signaling
-
Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB. 2005. VISA is an adapter protein required for virus-triggered IFN-β signaling. Mol. Cell 19:727-40
-
(2005)
Mol. Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
Li, L.Y.4
Zhai, Z.5
Shu, H.B.6
-
94
-
-
10344259136
-
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-β promoter
-
Andrejeva J, Childs KS, Young DF, Carlos TS, Stock N, et al. 2004. The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-β promoter. Proc. Natl. Acad. Sci. USA 101:17264-69
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17264-17269
-
-
Andrejeva, J.1
Childs, K.S.2
Young, D.F.3
Carlos, T.S.4
Stock, N.5
-
95
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, et al. 2005. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J. Immunol. 175:2851-58
-
(2005)
J. Immunol
, vol.175
, pp. 2851-2858
-
-
Yoneyama, M.1
Kikuchi, M.2
Matsumoto, K.3
Imaizumi, T.4
Miyagishi, M.5
-
96
-
-
22544455673
-
Cell type-specific involvement of RIG-I in antiviral response
-
Kato H, Sato S, Yoneyama M, Yamamoto M, Uematsu S, et al. 2005. Cell type-specific involvement of RIG-I in antiviral response. Immunity 23:19-28
-
(2005)
Immunity
, vol.23
, pp. 19-28
-
-
Kato, H.1
Sato, S.2
Yoneyama, M.3
Yamamoto, M.4
Uematsu, S.5
-
97
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, et al. 2006. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441:101-5
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
-
98
-
-
26844503987
-
The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I
-
Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, et al. 2005. The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I. J. Immunol. 175:5260-68
-
(2005)
J. Immunol
, vol.175
, pp. 5260-5268
-
-
Rothenfusser, S.1
Goutagny, N.2
DiPerna, G.3
Gong, M.4
Monks, B.G.5
-
99
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
-
Martinon F, Burns K, Tschopp J. 2002. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol. Cell 10:417-26
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
100
-
-
0035937797
-
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis
-
Chu ZL, Pio F, Xie Z, Welsh K, Krajewska M, et al. 2001. A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis. J. Biol. Chem. 276:9239-45
-
(2001)
J. Biol. Chem
, vol.276
, pp. 9239-9245
-
-
Chu, Z.L.1
Pio, F.2
Xie, Z.3
Welsh, K.4
Krajewska, M.5
-
101
-
-
0035937775
-
Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins
-
Hlaing T, Guo RF, Dilley KA, Loussia JM, Morrish TA, et al. 2001. Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins. J. Biol. Chem. 276:9230-38
-
(2001)
J. Biol. Chem
, vol.276
, pp. 9230-9238
-
-
Hlaing, T.1
Guo, R.F.2
Dilley, K.A.3
Loussia, J.M.4
Morrish, T.A.5
-
102
-
-
0033607768
-
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
-
Masumoto J, Taniguchi S, Ayukawa K, Sarvotham H, Kishino T, et al. 1999. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J. Biol. Chem. 274:33835-38
-
(1999)
J. Biol. Chem
, vol.274
, pp. 33835-33838
-
-
Masumoto, J.1
Taniguchi, S.2
Ayukawa, K.3
Sarvotham, H.4
Kishino, T.5
-
103
-
-
0035919723
-
Solution structure of the tumor necrosis factor receptor-1 death domain
-
Sukits SF, Lin LL, Hsu S, Malakian K, Powers R, Xu GY. 2001. Solution structure of the tumor necrosis factor receptor-1 death domain. J. Mol. Biol. 310:895-906
-
(2001)
J. Mol. Biol
, vol.310
, pp. 895-906
-
-
Sukits, S.F.1
Lin, L.L.2
Hsu, S.3
Malakian, K.4
Powers, R.5
Xu, G.Y.6
-
104
-
-
0030851905
-
NMR structure of the death domain of the p75 neurotrophin receptor
-
Liepinsh E, Ilag LL, Otting G, Ibanez CF. 1997. NMR structure of the death domain of the p75 neurotrophin receptor. EMBO J. 16:4999-5005
-
(1997)
EMBO J
, vol.16
, pp. 4999-5005
-
-
Liepinsh, E.1
Ilag, L.L.2
Otting, G.3
Ibanez, C.F.4
-
105
-
-
25444503240
-
Cutting edge: Molecular structure of the IL-1R-associated kinase-4 death domain and its implications for TLR signaling
-
Lasker MV, Gajjar MM, Nair SK. 2005. Cutting edge: molecular structure of the IL-1R-associated kinase-4 death domain and its implications for TLR signaling. J. Immunol. 175:4175-79
-
(2005)
J. Immunol
, vol.175
, pp. 4175-4179
-
-
Lasker, M.V.1
Gajjar, M.M.2
Nair, S.K.3
-
106
-
-
0033522889
-
The solution structure of FADD death domain: Structural basis of death domain interactions of Fas and FADD
-
Jeong EJ, Bang S, Lee TH, Park YI, Sim WS, Kim KS. 1999. The solution structure of FADD death domain: structural basis of death domain interactions of Fas and FADD. J. Biol. Chem. 274:16337-42
-
(1999)
J. Biol. Chem
, vol.274
, pp. 16337-16342
-
-
Jeong, E.J.1
Bang, S.2
Lee, T.H.3
Park, Y.I.4
Sim, W.S.5
Kim, K.S.6
-
107
-
-
0034622940
-
The three-dimensional solution structure and dynamic properties of the human FADD death domain
-
Berglund H, Olerenshaw D, Sankar A, Federwisch M, McDonald NQ, Driscoll PC. 2000. The three-dimensional solution structure and dynamic properties of the human FADD death domain. J. Mol. Biol. 302:171-88
-
(2000)
J. Mol. Biol
, vol.302
, pp. 171-188
-
-
Berglund, H.1
Olerenshaw, D.2
Sankar, A.3
Federwisch, M.4
McDonald, N.Q.5
Driscoll, P.C.6
-
108
-
-
33344467158
-
Crystal structure of RAIDD death domain implicates potential mechanism of PIDDosome assembly
-
Park HH, Wu H. 2006. Crystal structure of RAIDD death domain implicates potential mechanism of PIDDosome assembly. J. Mol. Biol. 357:358-64
-
(2006)
J. Mol. Biol
, vol.357
, pp. 358-364
-
-
Park, H.H.1
Wu, H.2
-
109
-
-
0033601077
-
Three-dimensional structure of a complex between the death domains of Pelle and Tube
-
Xiao T, Towb P, Wasserman SA, Sprang SR. 1999. Three-dimensional structure of a complex between the death domains of Pelle and Tube. Cell 99:545-55
-
(1999)
Cell
, vol.99
, pp. 545-555
-
-
Xiao, T.1
Towb, P.2
Wasserman, S.A.3
Sprang, S.R.4
-
110
-
-
0842307067
-
Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning
-
Sun H, Towb P, Chiem DN, Foster BA, Wasserman SA. 2004. Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning. EMBO J. 23:100-10
-
(2004)
EMBO J
, vol.23
, pp. 100-110
-
-
Sun, H.1
Towb, P.2
Chiem, D.N.3
Foster, B.A.4
Wasserman, S.A.5
-
111
-
-
13044282468
-
Defective CD95/APO-l/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia
-
Martin DA, Zheng L, Siegel RM, Huang B, Fisher GH, et al. 1999. Defective CD95/APO-l/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia. Proc. Natl. Acad. Sci. USA 96:4552-57
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4552-4557
-
-
Martin, D.A.1
Zheng, L.2
Siegel, R.M.3
Huang, B.4
Fisher, G.H.5
-
112
-
-
0347723881
-
Identification of an expanded binding surface on the FADD death domain responsible for interaction with CD95/Fas
-
Hill JM, Morisawa G, Kim T, Huang T, Wei Y, Werner MH. 2004. Identification of an expanded binding surface on the FADD death domain responsible for interaction with CD95/Fas. J. Biol. Chem. 279:1474-81
-
(2004)
J. Biol. Chem
, vol.279
, pp. 1474-1481
-
-
Hill, J.M.1
Morisawa, G.2
Kim, T.3
Huang, T.4
Wei, Y.5
Werner, M.H.6
-
113
-
-
0029967670
-
Systematic mutational analysis of the death domain of the tumor necrosis factor receptor-1-associated protein TRADD
-
Park A, Baichwal VR. 1996. Systematic mutational analysis of the death domain of the tumor necrosis factor receptor-1-associated protein TRADD. J. Biol. Chem. 271:9858-62
-
(1996)
J. Biol. Chem
, vol.271
, pp. 9858-9862
-
-
Park, A.1
Baichwal, V.R.2
-
114
-
-
0034725548
-
Mutational analysis and NMR studies of the death domain of the tumor necrosis factor receptor-1
-
Telliez JB, Xu GY, Woronicz JD, Hsu S, Wu JL, et al. 2000. Mutational analysis and NMR studies of the death domain of the tumor necrosis factor receptor-1. J. Mol. Biol. 300:1323-33
-
(2000)
J. Mol. Biol
, vol.300
, pp. 1323-1333
-
-
Telliez, J.B.1
Xu, G.Y.2
Woronicz, J.D.3
Hsu, S.4
Wu, J.L.5
-
115
-
-
0035896406
-
A docking model of key components of the DISC complex: Death domain superfamily interactions redefined
-
Weber CH, Vincenz C. 2001. A docking model of key components of the DISC complex: death domain superfamily interactions redefined. FEBS Lett. 492:171-76
-
(2001)
FEBS Lett
, vol.492
, pp. 171-176
-
-
Weber, C.H.1
Vincenz, C.2
-
116
-
-
29144463250
-
Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition
-
Yang JK, Wang L, Zheng L, Wan F, Ahmed M, et al. 2005. Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition. Mol. Cell 20:939-49
-
(2005)
Mol. Cell
, vol.20
, pp. 939-949
-
-
Yang, J.K.1
Wang, L.2
Zheng, L.3
Wan, F.4
Ahmed, M.5
-
117
-
-
33744506980
-
FADD self-association is required for stable interaction with an activated death receptor
-
Sandu C, Morisawa G, Wegorzewska I, Huang T, Arechiga AF, et al. 2006. FADD self-association is required for stable interaction with an activated death receptor. Cell Death Differ. 13:2052-61
-
(2006)
Cell Death Differ
, vol.13
, pp. 2052-2061
-
-
Sandu, C.1
Morisawa, G.2
Wegorzewska, I.3
Huang, T.4
Arechiga, A.F.5
-
118
-
-
0037011120
-
Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain
-
Hill JM, Vaidyanathan H, Ramos JW, Ginsberg MH, Werner MH. 2002. Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain. EMBO J. 21:6494-504
-
(2002)
EMBO J
, vol.2
, Issue.1
, pp. 6494-6504
-
-
Hill, J.M.1
Vaidyanathan, H.2
Ramos, J.W.3
Ginsberg, M.H.4
Werner, M.H.5
-
119
-
-
33744539048
-
The structure of FADD and its mode of interaction with procaspase-8
-
Carrington PE, Sandu C, Wei Y, Hill JM, Morisawa G, et al. 2006. The structure of FADD and its mode of interaction with procaspase-8. Mol. Cell 22:599-610
-
(2006)
Mol. Cell
, vol.22
, pp. 599-610
-
-
Carrington, P.E.1
Sandu, C.2
Wei, Y.3
Hill, J.M.4
Morisawa, G.5
-
120
-
-
33646377433
-
Crystal structure of a viral FLIP: Insights into FLIP-mediated inhibition of death receptor signaling
-
Li FY, Jeffrey PD, Yu JW, Shi Y. 2006. Crystal structure of a viral FLIP: insights into FLIP-mediated inhibition of death receptor signaling. J. Biol. Chem. 281:2960-68
-
(2006)
J. Biol. Chem
, vol.281
, pp. 2960-2968
-
-
Li, F.Y.1
Jeffrey, P.D.2
Yu, J.W.3
Shi, Y.4
-
121
-
-
33744517489
-
2 006. Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis
-
Muppidi JR, Lobito AA, Ramaswamy M, Yang JK, Wang L, et al. 2 006. Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis. Cell Death Differ. 13:1641-50
-
Cell Death Differ
, vol.13
, pp. 1641-1650
-
-
Muppidi, J.R.1
Lobito, A.A.2
Ramaswamy, M.3
Yang, J.K.4
Wang, L.5
-
122
-
-
0032738099
-
Crystal structure of Apaf-1 caspase recruitment domain: An α-helical Greek key fold for apoptotic signaling
-
Vaughn DE, Rodriguez J, Lazebnik Y, Joshua-Tor L. 1999. Crystal structure of Apaf-1 caspase recruitment domain: an α-helical Greek key fold for apoptotic signaling. J. Mol. Biol. 293:439-47
-
(1999)
J. Mol. Biol
, vol.293
, pp. 439-447
-
-
Vaughn, D.E.1
Rodriguez, J.2
Lazebnik, Y.3
Joshua-Tor, L.4
-
123
-
-
17244368276
-
Structure of the apoptotic protease-activating factor 1 bound to ADP
-
Riedl SJ, Li W, Chao Y, Schwarzenbacher R, Shi Y. 2005. Structure of the apoptotic protease-activating factor 1 bound to ADP. Nature 434:926-33
-
(2005)
Nature
, vol.434
, pp. 926-933
-
-
Riedl, S.J.1
Li, W.2
Chao, Y.3
Schwarzenbacher, R.4
Shi, Y.5
-
124
-
-
0033542482
-
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
-
Qin H, Srinivasula SM, Wu G, Fernandes-Alnemri T, Alnemri ES, Shi Y. 1999. Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature 399:549-57
-
(1999)
Nature
, vol.399
, pp. 549-557
-
-
Qin, H.1
Srinivasula, S.M.2
Wu, G.3
Fernandes-Alnemri, T.4
Alnemri, E.S.5
Shi, Y.6
-
125
-
-
26844485563
-
Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans
-
Yan N, Chai J, Lee ES, Gu L, Liu Q, et al. 2005. Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature 43 7:831-37
-
(2005)
Nature
, vol.43
, Issue.7
, pp. 831-837
-
-
Yan, N.1
Chai, J.2
Lee, E.S.3
Gu, L.4
Liu, Q.5
-
126
-
-
27644483812
-
A structure of the human apoptosome at 12.8 Å resolution provides insights into this cell death platform
-
Yu X, Acehan D, Menetret JF, Booth CR, Ludtke SJ, et al. 2005. A structure of the human apoptosome at 12.8 Å resolution provides insights into this cell death platform. Structure 13:1725-35
-
(2005)
Structure
, vol.13
, pp. 1725-1735
-
-
Yu, X.1
Acehan, D.2
Menetret, J.F.3
Booth, C.R.4
Ludtke, S.J.5
-
127
-
-
0037007101
-
Oligomerization and activation of caspase-9, induced by Apaf-1 CARD
-
Shiozaki EN, Chai J, Shi Y. 2002. Oligomerization and activation of caspase-9, induced by Apaf-1 CARD. Proc. Natl. Acad. Sci. USA 99:4197-202
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4197-4202
-
-
Shiozaki, E.N.1
Chai, J.2
Shi, Y.3
-
128
-
-
0042386425
-
The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
-
Liepinsh E, Barbals R, Dahl E, Sharipo A, Staub E, Otting G. 2003. The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition. J. Mol. Biol. 332:1155-63
-
(2003)
J. Mol. Biol
, vol.332
, pp. 1155-1163
-
-
Liepinsh, E.1
Barbals, R.2
Dahl, E.3
Sharipo, A.4
Staub, E.5
Otting, G.6
-
129
-
-
0141483209
-
Folding pyrin into the family
-
Eliezer D. 2003. Folding pyrin into the family. Structure 11:1190-91
-
(2003)
Structure
, vol.11
, pp. 1190-1191
-
-
Eliezer, D.1
-
130
-
-
0034520137
-
The PYRIN domain: A novel motif found in apoptosis and inflammation proteins
-
Bertin J, DiStefano PS. 2000. The PYRIN domain: a novel motif found in apoptosis and inflammation proteins. Cell Death Differ. 7:1273-74
-
(2000)
Cell Death Differ
, vol.7
, pp. 1273-1274
-
-
Bertin, J.1
DiStefano, P.S.2
-
131
-
-
0035916324
-
The pyrin domain: A possible member of the death domain-fold family implicated in apoptosis and inflammation
-
Martinon F, Hofmann K, Tschopp J. 2001. The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation. Curr. Biol. 11:R118-20
-
(2001)
Curr. Biol
, vol.11
-
-
Martinon, F.1
Hofmann, K.2
Tschopp, J.3
-
132
-
-
0035253123
-
PAAD: A new protein domain associated with apoptosis, cancer and autoimmune diseases
-
Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. 2001. PAAD: a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem. Sci. 26:85-87
-
(2001)
Trends Biochem. Sci
, vol.26
, pp. 85-87
-
-
Pawlowski, K.1
Pio, F.2
Chu, Z.3
Reed, J.C.4
Godzik, A.5
-
133
-
-
0035425256
-
The death domain superfamily: A tale of two interfaces?
-
Weber CH, Vincenz C. 2001. The death domain superfamily: a tale of two interfaces? Trends Biochem. Sci. 26:475-81
-
(2001)
Trends Biochem. Sci
, vol.26
, pp. 475-481
-
-
Weber, C.H.1
Vincenz, C.2
-
134
-
-
0037063338
-
Identification of a basic surface area of the FADD death effector domain critical for apoptotic signaling
-
Kaufmann M, Bozic D, Briand C, Bodmer JL, Zerbe O, et al. 2002. Identification of a basic surface area of the FADD death effector domain critical for apoptotic signaling. FEBS Lett. 527:250-54
-
(2002)
FEBS Lett
, vol.527
, pp. 250-254
-
-
Kaufmann, M.1
Bozic, D.2
Briand, C.3
Bodmer, J.L.4
Zerbe, O.5
-
135
-
-
0036657283
-
Fire and ICE: The role of pyrin domain-containing proteins in inflammation and apoptosis
-
Gumucio DL, Diaz A, Schaner P, Richards N, Babcock C, et al. 2002. Fire and ICE: the role of pyrin domain-containing proteins in inflammation and apoptosis. Clin. Exp. Rheumatol. 20:S45-53
-
(2002)
Clin. Exp. Rheumatol
, vol.20
-
-
Gumucio, D.L.1
Diaz, A.2
Schaner, P.3
Richards, N.4
Babcock, C.5
-
136
-
-
12144284412
-
Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC
-
Moriya M, Taniguchi S, Wu P, Liepinsh E, Otting G, Sagara J. 2005. Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC. Biochemistry 44:575-83
-
(2005)
Biochemistry
, vol.44
, pp. 575-583
-
-
Moriya, M.1
Taniguchi, S.2
Wu, P.3
Liepinsh, E.4
Otting, G.5
Sagara, J.6
-
137
-
-
16944365196
-
A candidate gene for familial Mediterranean fever
-
Consortium TFF
-
Consortium TFF. 1997. A candidate gene for familial Mediterranean fever. Nat. Genet. 17:25-31
-
(1997)
Nat. Genet
, vol.17
, pp. 25-31
-
-
-
138
-
-
0035179970
-
2 001. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. 2 001. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat. Genet. 29:301-5
-
Nat. Genet
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
139
-
-
0035189451
-
A fever gene comes in from the cold
-
Kastner DL, O'Shea JJ. 2001. A fever gene comes in from the cold. Nat. Genet. 29:241-42
-
(2001)
Nat. Genet
, vol.29
, pp. 241-242
-
-
Kastner, D.L.1
O'Shea, J.J.2
-
140
-
-
33344476398
-
CATERPILLERs, pyrin and hereditary immunological disorders
-
Ting JP, Kastner DL, Hoffman HM. 2006. CATERPILLERs, pyrin and hereditary immunological disorders. Nat. Rev. Immunol. 6:183-95
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 183-195
-
-
Ting, J.P.1
Kastner, D.L.2
Hoffman, H.M.3
-
141
-
-
4644354531
-
Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions
-
Nam YJ, Mani K, Ashton AW, Peng CF, Krishnamurthy B, et al. 2004. Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions. Mol. Cell 15:901-12
-
(2004)
Mol. Cell
, vol.15
, pp. 901-912
-
-
Nam, Y.J.1
Mani, K.2
Ashton, A.W.3
Peng, C.F.4
Krishnamurthy, B.5
|