Critical role for NALP3/CIAS1/cryopyrin in innate and adaptive immunity through its regulation of caspase-1

Immunity

Volumn 24, Issue 3, 2006, Pages 317-327

  Sutterwala, Fayyaz S ^a   Ogura, Yasunori ^a   Szczepanik, Marian ^a,b   Lara Tejero, Maria ^c   Lichtenberger, G Scott ^a   Grant, Ethan P ^d,e   Bertin, John ^d,e   Coyle, Anthony J ^d,f   Galán, Jorge E ^c   Askenase, Philip W ^a   Flavell, Richard A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MILLENNIUM PHARMACEUTICALS INC   (United States)

^e Synta Pharmaceuticals Corp   (United States)

^f MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; ENDOTOXIN; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; PROTEIN CIAS1; PROTEIN CRYOPYRIN; PROTEIN NALP3; TRINITROPHENYLHAPTEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTACT ALLERGY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; SALMONELLA TYPHIMURIUM;

ADENOSINE TRIPHOSPHATE; ANIMALS; AUTOIMMUNE DISEASES; CARRIER PROTEINS; CASPASE 1; CYTOSKELETAL PROTEINS; ENZYME ACTIVATION; IMMUNITY, NATURAL; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; RNA, MESSENGER; SALMONELLA TYPHIMURIUM; SHOCK, SEPTIC; TOLL-LIKE RECEPTORS;

EID: 33644985564     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2006.02.004     Document Type: Article

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