-
1
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
Acehan D., Jiang X., Morgan D.G., Heuser J.E., Wang X., Akey C.W. Three-dimensional structure of the apoptosome. implications for assembly, procaspase-9 binding, and activation Mol. Cell. 9:2002;423-432
-
(2002)
Mol. Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
Jiang, X.2
Morgan, D.G.3
Heuser, J.E.4
Wang, X.5
Akey, C.W.6
-
2
-
-
0036745064
-
Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis
-
Aganna E., Martinon F., Hawkins P.N., Ross J.B., Swan D.C., Booth D.R., Lachmann H.J., Bybee A., Gaudet R., Woo P., et al. Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum. 46:2002;2445-2452
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 2445-2452
-
-
Aganna, E.1
Martinon, F.2
Hawkins, P.N.3
Ross, J.B.4
Swan, D.C.5
Booth, D.R.6
Lachmann, H.J.7
Bybee, A.8
Gaudet, R.9
Woo, P.10
-
3
-
-
1642285783
-
NALP3 forms an IL-1b processing inflammasome with increased activity in Muckle-Wells auto-inflammatory disorder
-
Agostini L., Martinon F., Burns K., McDermott E.M., Hawkins P.N., Tschopp J. NALP3 forms an IL-1b processing inflammasome with increased activity in Muckle-Wells auto-inflammatory disorder. Immunity. 20:2004;319-325
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, E.M.4
Hawkins, P.N.5
Tschopp, J.6
-
4
-
-
0036667263
-
IFN-gamma upregulates apoptosis-related molecules and enhances Fas-mediated apoptosis in human cholangiocarcinoma
-
Ahn E.Y., Pan G., Vickers S.M., McDonald J.M. IFN-gamma upregulates apoptosis-related molecules and enhances Fas-mediated apoptosis in human cholangiocarcinoma. Int. J. Cancer. 100:2002;445-451
-
(2002)
Int. J. Cancer
, vol.100
, pp. 445-451
-
-
Ahn, E.Y.1
Pan, G.2
Vickers, S.M.3
McDonald, J.M.4
-
5
-
-
0242626505
-
Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2
-
Albrecht M., Domingues F.S., Schreiber S., Lengauer T. Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2. FEBS Lett. 554:2003;520-528
-
(2003)
FEBS Lett.
, vol.554
, pp. 520-528
-
-
Albrecht, M.1
Domingues, F.S.2
Schreiber, S.3
Lengauer, T.4
-
6
-
-
0032923377
-
The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles
-
Andrei C., Dazzi C., Lotti L., Torrisi M.R., Chimini G., Rubartelli A. The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles. Mol. Biol. Cell. 10:1999;1463-1475
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 1463-1475
-
-
Andrei, C.1
Dazzi, C.2
Lotti, L.3
Torrisi, M.R.4
Chimini, G.5
Rubartelli, A.6
-
7
-
-
0033568456
-
Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9
-
Annand R.R., Dahlen J.R., Sprecher C.A., De Dreu P., Foster D.C., Mankovich J.A., Talanian R.V., Kisiel W., Giegel D.A. Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9. Biochem. J. 342:1999;655-665
-
(1999)
Biochem. J.
, vol.342
, pp. 655-665
-
-
Annand, R.R.1
Dahlen, J.R.2
Sprecher, C.A.3
De Dreu, P.4
Foster, D.C.5
Mankovich, J.A.6
Talanian, R.V.7
Kisiel, W.8
Giegel, D.A.9
-
8
-
-
0023155095
-
Studies on the molecular nature of human interleukin 1
-
Auron P.E., Warner S.J., Webb A.C., Cannon J.G., Bernheim H.A., McAdam K.J., Rosenwasser L.J., LoPreste G., Mucci S.F., Dinarello C.A. Studies on the molecular nature of human interleukin 1. J. Immunol. 138:1987;1447-1456
-
(1987)
J. Immunol.
, vol.138
, pp. 1447-1456
-
-
Auron, P.E.1
Warner, S.J.2
Webb, A.C.3
Cannon, J.G.4
Bernheim, H.A.5
McAdam, K.J.6
Rosenwasser, L.J.7
Lopreste, G.8
Mucci, S.F.9
Dinarello, C.A.10
-
9
-
-
19044371418
-
Caspase-8 and Apaf-1-independent caspase-9 activation in Sendai virus-infected cells
-
Bitzer M., Armeanu S., Prinz F., Ungerechts G., Wybranietz W., Spiegel M., Bernlohr C., Cecconi F., Gregor M., Neubert W.J., et al. Caspase-8 and Apaf-1-independent caspase-9 activation in Sendai virus-infected cells. J. Biol. Chem. 277:2002;29817-29824
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29817-29824
-
-
Bitzer, M.1
Armeanu, S.2
Prinz, F.3
Ungerechts, G.4
Wybranietz, W.5
Spiegel, M.6
Bernlohr, C.7
Cecconi, F.8
Gregor, M.9
Neubert, W.J.10
-
10
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright K.M., Renatus M., Scott F.L., Sperandio S., Shin H., Pedersen I.M., Ricci J.E., Edris W.A., Sutherlin D.P., Green D.R., Salvesen G.S. A unified model for apical caspase activation. Mol. Cell. 11:2003;529-541
-
(2003)
Mol. Cell
, vol.11
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
Ricci, J.E.7
Edris, W.A.8
Sutherlin, D.P.9
Green, D.R.10
Salvesen, G.S.11
-
12
-
-
0035941220
-
CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways
-
Bouchier-Hayes L., Conroy H., Egan H., Adrain C., Creagh E.M., MacFarlane M., Martin S.J. CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways. J. Biol. Chem. 276:2001;44069-44077
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44069-44077
-
-
Bouchier-Hayes, L.1
Conroy, H.2
Egan, H.3
Adrain, C.4
Creagh, E.M.5
MacFarlane, M.6
Martin, S.J.7
-
13
-
-
0022413392
-
Amino acid sequence analysis of human interleukin 1 (IL-1). Evidence for biochemically distinct forms of IL-1
-
Cameron P., Limjuco G., Rodkey J., Bennett C., Schmidt J.A. Amino acid sequence analysis of human interleukin 1 (IL-1). Evidence for biochemically distinct forms of IL-1. J. Exp. Med. 162:1985;790-801
-
(1985)
J. Exp. Med.
, vol.162
, pp. 790-801
-
-
Cameron, P.1
Limjuco, G.2
Rodkey, J.3
Bennett, C.4
Schmidt, J.A.5
-
14
-
-
0026517239
-
Molecular cloning of the interleukin-1 beta converting enzyme
-
Cerretti D.P., Kozlosky C.J., Mosley B., Nelson N., Van Ness K., Greenstreet T.A., March C.J., Kronheim S.R., Druck T., Cannizzaro L.A., et al. Molecular cloning of the interleukin-1 beta converting enzyme. Science. 256:1992;97-100
-
(1992)
Science
, vol.256
, pp. 97-100
-
-
Cerretti, D.P.1
Kozlosky, C.J.2
Mosley, B.3
Nelson, N.4
Van Ness, K.5
Greenstreet, T.A.6
March, C.J.7
Kronheim, S.R.8
Druck, T.9
Cannizzaro, L.A.10
-
15
-
-
0037349294
-
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
-
Chae J.J., Komarow H.D., Cheng J., Wood G., Raben N., Liu P.P., Kastner D.L. Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol. Cell. 11:2003;591-604
-
(2003)
Mol. Cell
, vol.11
, pp. 591-604
-
-
Chae, J.J.1
Komarow, H.D.2
Cheng, J.3
Wood, G.4
Raben, N.5
Liu, P.P.6
Kastner, D.L.7
-
16
-
-
0041827164
-
Nods, Nalps and Naip: Intracellular regulators of bacterial-induced inflammation
-
Chamaillard M., Girardin S.E., Viala J., Philpott D.J. Nods, Nalps and Naip. intracellular regulators of bacterial-induced inflammation Cell. Microbiol. 5:2003;581-592
-
(2003)
Cell. Microbiol.
, vol.5
, pp. 581-592
-
-
Chamaillard, M.1
Girardin, S.E.2
Viala, J.3
Philpott, D.J.4
-
17
-
-
0027333432
-
Dissociation of IL-1 beta synthesis and secretion in human blood monocytes stimulated with bacterial cell wall products
-
Chin J., Kostura M.J. Dissociation of IL-1 beta synthesis and secretion in human blood monocytes stimulated with bacterial cell wall products. J. Immunol. 151:1993;5574-5585
-
(1993)
J. Immunol.
, vol.151
, pp. 5574-5585
-
-
Chin, J.1
Kostura, M.J.2
-
18
-
-
0035028649
-
Role of p53-dependent activation of caspases in chronic obstructive uropathy: Evidence from p53 null mutant mice
-
Choi Y.J., Mendoza L., Rha S.J., Sheikh-Hamad D., Baranowska-Daca E., Nguyen V., Smith C.W., Nassar G., Suki W.N., Truong L.D. Role of p53-dependent activation of caspases in chronic obstructive uropathy. evidence from p53 null mutant mice J. Am. Soc. Nephrol. 12:2001;983-992
-
(2001)
J. Am. Soc. Nephrol.
, vol.12
, pp. 983-992
-
-
Choi, Y.J.1
Mendoza, L.2
Rha, S.J.3
Sheikh-Hamad, D.4
Baranowska-Daca, E.5
Nguyen, V.6
Smith, C.W.7
Nassar, G.8
Suki, W.N.9
Truong, L.D.10
-
19
-
-
0035937797
-
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis
-
Chu Z.L., Pio F., Xie Z., Welsh K., Krajewska M., Krajewski S., Godzik A., Reed J.C. A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis. J. Biol. Chem. 276:2001;9239-9245
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9239-9245
-
-
Chu, Z.L.1
Pio, F.2
Xie, Z.3
Welsh, K.4
Krajewska, M.5
Krajewski, S.6
Godzik, A.7
Reed, J.C.8
-
20
-
-
18544383460
-
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
-
Chun H.J., Zheng L., Ahmad M., Wang J., Speirs C.K., Siegel R.M., Dale J.K., Puck J., Davis J., Hall C.G., et al. Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature. 419:2002;395-399
-
(2002)
Nature
, vol.419
, pp. 395-399
-
-
Chun, H.J.1
Zheng, L.2
Ahmad, M.3
Wang, J.4
Speirs, C.K.5
Siegel, R.M.6
Dale, J.K.7
Puck, J.8
Davis, J.9
Hall, C.G.10
-
21
-
-
0033676843
-
TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers
-
Conway K.E., McConnell B.B., Bowring C.E., Donald C.D., Warren S.T., Vertino P.M. TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers. Cancer Res. 60:2000;6236-6242
-
(2000)
Cancer Res.
, vol.60
, pp. 6236-6242
-
-
Conway, K.E.1
McConnell, B.B.2
Bowring, C.E.3
Donald, C.D.4
Warren, S.T.5
Vertino, P.M.6
-
22
-
-
0033358561
-
Genetic linkage of the Muckle-Wells syndrome to chromosome 1q44
-
Cuisset L., Drenth J.P., Berthelot J.M., Meyrier A., Vaudour G., Watts R.A., Scott D.G., Nicholls A., Pavek S., Vasseur C., et al. Genetic linkage of the Muckle-Wells syndrome to chromosome 1q44. Am. J. Hum. Genet. 65:1999;1054-1059
-
(1999)
Am. J. Hum. Genet.
, vol.65
, pp. 1054-1059
-
-
Cuisset, L.1
Drenth, J.P.2
Berthelot, J.M.3
Meyrier, A.4
Vaudour, G.5
Watts, R.A.6
Scott, D.G.7
Nicholls, A.8
Pavek, S.9
Vasseur, C.10
-
23
-
-
0034964518
-
CLAN, a novel human CED-4-like gene
-
Damiano J.S., Stehlik C., Pio F., Godzik A., Reed J.C. CLAN, a novel human CED-4-like gene. Genomics. 75:2001;77-83
-
(2001)
Genomics
, vol.75
, pp. 77-83
-
-
Damiano, J.S.1
Stehlik, C.2
Pio, F.3
Godzik, A.4
Reed, J.C.5
-
25
-
-
2542452727
-
Cryopyrin induced IL-1 secretion in monocytic cells: Enhanced activity of disease-associated mutants and requirement for ASC
-
in press. Published online March 12, 2004.
-
Dowds, T.A., Masumoto, J., Zhu, L., Inohara, N., and Nunez, G. (2004). Cryopyrin induced IL-1 secretion in monocytic cells: Enhanced activity of disease-associated mutants and requirement for ASC. J. Biol. Chem., in press. Published online March 12, 2004.
-
(2004)
J. Biol. Chem.
-
-
Dowds, T.A.1
Masumoto, J.2
Zhu, L.3
Inohara, N.4
Nunez, G.5
-
26
-
-
0034743434
-
Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins
-
Druilhe A., Srinivasula S.M., Razmara M., Ahmad M., Alnemri E.S. Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins. Cell Death Differ. 8:2001;649-657
-
(2001)
Cell Death Differ.
, vol.8
, pp. 649-657
-
-
Druilhe, A.1
Srinivasula, S.M.2
Razmara, M.3
Ahmad, M.4
Alnemri, E.S.5
-
27
-
-
0034523695
-
Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation
-
Eckhart L., Declercq W., Ban J., Rendl M., Lengauer B., Mayer C., Lippens S., Vandenabeele P., Tschachler E. Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation. J. Invest. Dermatol. 115:2000;1148-1151
-
(2000)
J. Invest. Dermatol.
, vol.115
, pp. 1148-1151
-
-
Eckhart, L.1
Declercq, W.2
Ban, J.3
Rendl, M.4
Lengauer, B.5
Mayer, C.6
Lippens, S.7
Vandenabeele, P.8
Tschachler, E.9
-
28
-
-
0034792109
-
Lessons from interleukin-deficient mice: The interleukin-1 system
-
Fantuzzi G. Lessons from interleukin-deficient mice. the interleukin-1 system Acta Physiol. Scand. 173:2001;5-9
-
(2001)
Acta Physiol. Scand.
, vol.173
, pp. 5-9
-
-
Fantuzzi, G.1
-
29
-
-
0034644508
-
Insights into programmed cell death through structural biology
-
Fesik S.W. Insights into programmed cell death through structural biology. Cell. 103:2000;273-282
-
(2000)
Cell
, vol.103
, pp. 273-282
-
-
Fesik, S.W.1
-
30
-
-
0037144586
-
A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta
-
Fiorentino L., Stehlik C., Oliveira V., Ariza M.E., Godzik A., Reed J.C. A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta. J. Biol. Chem. 277:2002;35333-35340
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 35333-35340
-
-
Fiorentino, L.1
Stehlik, C.2
Oliveira, V.3
Ariza, M.E.4
Godzik, A.5
Reed, J.C.6
-
32
-
-
16944365196
-
A candidate gene for familial Mediterranean fever
-
The French F.M.F., Consortium A candidate gene for familial Mediterranean fever. Nat. Genet. 17:1997;25-31
-
(1997)
Nat. Genet.
, vol.17
, pp. 25-31
-
-
The French, F.M.F.1
Consortium2
-
33
-
-
0037417220
-
Apoptosis and caspases in neurodegenerative diseases
-
Friedlander R.M. Apoptosis and caspases in neurodegenerative diseases. N. Engl. J. Med. 348:2003;1365-1375
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1365-1375
-
-
Friedlander, R.M.1
-
34
-
-
0032484008
-
Inhibition of human caspases by peptide-based and macromolecular inhibitors
-
Garcia-Calvo M., Peterson E.P., Leiting B., Ruel R., Nicholson D.W., Thornberry N.A. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J. Biol. Chem. 273:1998;32608-32613
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32608-32613
-
-
Garcia-Calvo, M.1
Peterson, E.P.2
Leiting, B.3
Ruel, R.4
Nicholson, D.W.5
Thornberry, N.A.6
-
35
-
-
0034815799
-
Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis
-
Geddes B.J., Wang L., Huang W.J., Lavellee M., Manji G.A., Brown M., Jurman M., Cao J., Morgenstern J., Merriam S., et al. Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis. Biochem. Biophys. Res. Commun. 284:2001;77-82
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.284
, pp. 77-82
-
-
Geddes, B.J.1
Wang, L.2
Huang, W.J.3
Lavellee, M.4
Manji, G.A.5
Brown, M.6
Jurman, M.7
Cao, J.8
Morgenstern, J.9
Merriam, S.10
-
38
-
-
0037108346
-
Cutting edge: CATERPILLER: A large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains
-
Harton J.A., Linhoff M.W., Zhang J., Ting J.P. Cutting edge. CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains J. Immunol. 169:2002;4088-4093
-
(2002)
J. Immunol.
, vol.169
, pp. 4088-4093
-
-
Harton, J.A.1
Linhoff, M.W.2
Zhang, J.3
Ting, J.P.4
-
39
-
-
0037792866
-
Interleukin-1-receptor antagonist in the Muckle-Wells syndrome
-
Hawkins P.N., Lachmann H.J., McDermott M.F. Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. N. Engl. J. Med. 348:2003;2583-2584
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 2583-2584
-
-
Hawkins, P.N.1
Lachmann, H.J.2
McDermott, M.F.3
-
40
-
-
1042290321
-
Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra
-
Hawkins P.N., Lachmann H.J., Aganna E., McDermott M.F. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum. 50:2004;607-612
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 607-612
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Aganna, E.3
McDermott, M.F.4
-
41
-
-
0032721512
-
Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia
-
Hazan J., Fonknechten N., Mavel D., Paternotte C., Samson D., Artiguenave F., Davoine C.S., Cruaud C., Durr A., Wincker P., et al. Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia. Nat. Genet. 23:1999;296-303
-
(1999)
Nat. Genet.
, vol.23
, pp. 296-303
-
-
Hazan, J.1
Fonknechten, N.2
Mavel, D.3
Paternotte, C.4
Samson, D.5
Artiguenave, F.6
Davoine, C.S.7
Cruaud, C.8
Durr, A.9
Wincker, P.10
-
42
-
-
0142105406
-
Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein
-
Hetz C., Russelakis-Carneiro M., Maundrell K., Castilla J., Soto C. Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. EMBO J. 22:2003;5435-5445
-
(2003)
EMBO J.
, vol.22
, pp. 5435-5445
-
-
Hetz, C.1
Russelakis-Carneiro, M.2
Maundrell, K.3
Castilla, J.4
Soto, C.5
-
43
-
-
0141817846
-
NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain
-
Hiller S., Kohl A., Fiorito F., Herrmann T., Wider G., Tschopp J., Grutter M.G., Wuthrich K. NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain. Structure. 11:2003;1199-1205
-
(2003)
Structure
, vol.11
, pp. 1199-1205
-
-
Hiller, S.1
Kohl, A.2
Fiorito, F.3
Herrmann, T.4
Wider, G.5
Tschopp, J.6
Grutter, M.G.7
Wuthrich, K.8
-
44
-
-
0035176139
-
Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination
-
Hisahara S., Yuan J., Momoi T., Okano H., Miura M. Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination. J. Exp. Med. 193:2001;111-122
-
(2001)
J. Exp. Med.
, vol.193
, pp. 111-122
-
-
Hisahara, S.1
Yuan, J.2
Momoi, T.3
Okano, H.4
Miura, M.5
-
45
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and A{beta}-induced cell death
-
Published online May 3, 2004.
-
Hitomi J., Katayama T., Eguchi Y., Kudo T., Taniguchi M., Koyama Y., Manabe T., Yamagishi S., Bando Y., Imaizumi K., et al. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and A{beta}-induced cell death. J. Cell Biol. 165:2004;347-356. Published online May 3, 2004. 10.1083/jcb.200310015
-
(2004)
J. Cell Biol.
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Koyama, Y.6
Manabe, T.7
Yamagishi, S.8
Bando, Y.9
Imaizumi, K.10
-
46
-
-
0035937775
-
Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins
-
Hlaing T., Guo R.F., Dilley K.A., Loussia J.M., Morrish T.A., Shi M.M., Vincenz C., Ward P.A. Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins. J. Biol. Chem. 276:2001;9230-9238
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9230-9238
-
-
Hlaing, T.1
Guo, R.F.2
Dilley, K.A.3
Loussia, J.M.4
Morrish, T.A.5
Shi, M.M.6
Vincenz, C.7
Ward, P.A.8
-
47
-
-
0032807406
-
The modular nature of apoptotic signaling proteins
-
Hofmann K. The modular nature of apoptotic signaling proteins. Cell. Mol. Life Sci. 55:1999;1113-1128
-
(1999)
Cell. Mol. Life Sci.
, vol.55
, pp. 1113-1128
-
-
Hofmann, K.1
-
48
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
Hoffman H.M., Mueller J.L., Broide D.H., Wanderer A.A., Kolodner R.D. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat. Genet. 29:2001;301-305
-
(2001)
Nat. Genet.
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
49
-
-
0037317936
-
Fine structure mapping of CIAS1: Identification of an ancestral haplotype and a common FCAS mutation, L353P
-
Hoffman H.M., Gregory S.G., Mueller J.L., Tresierras M., Broide D.H., Wanderer A.A., Kolodner R.D. Fine structure mapping of CIAS1. identification of an ancestral haplotype and a common FCAS mutation, L353P Hum. Genet. 112:2003;209-216
-
(2003)
Hum. Genet.
, vol.112
, pp. 209-216
-
-
Hoffman, H.M.1
Gregory, S.G.2
Mueller, J.L.3
Tresierras, M.4
Broide, D.H.5
Wanderer, A.A.6
Kolodner, R.D.7
-
50
-
-
0037290889
-
Resistance gene signaling in plants-complex similarities to animal innate immunity
-
Holt B.F. 3rd, Hubert D.A., Dangl J.L. Resistance gene signaling in plants-complex similarities to animal innate immunity. Curr. Opin. Immunol. 15:2003;20-25
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 20-25
-
-
Holt III, B.F.1
Hubert, D.A.2
Dangl, J.L.3
-
51
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot J.P., Chamaillard M., Zouali H., Lesage S., Cezard J.P., Belaiche J., Almer S., Tysk C., O'Morain C.A., Gassull M., et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature. 411:2001;599-603
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'Morain, C.A.9
Gassull, M.10
-
52
-
-
0037216780
-
The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations
-
Hull K.M., Shoham N., Chae J.J., Aksentijevich I., Kastner D.L. The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations. Curr. Opin. Rheumatol. 15:2003;61-69
-
(2003)
Curr. Opin. Rheumatol.
, vol.15
, pp. 61-69
-
-
Hull, K.M.1
Shoham, N.2
Chae, J.J.3
Aksentijevich, I.4
Kastner, D.L.5
-
53
-
-
0034730325
-
Iceberg: A novel inhibitor of interleukin-1beta generation
-
Humke E.W., Shriver S.K., Starovasnik M.A., Fairbrother W.J., Dixit V.M. Iceberg. a novel inhibitor of interleukin-1beta generation Cell. 103:2000;99-111
-
(2000)
Cell
, vol.103
, pp. 99-111
-
-
Humke, E.W.1
Shriver, S.K.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
54
-
-
0035474227
-
The NOD: A signaling module that regulates apoptosis and host defense against pathogens
-
Inohara N., Nunez G. The NOD. a signaling module that regulates apoptosis and host defense against pathogens Oncogene. 20:2001;6473-6481
-
(2001)
Oncogene
, vol.20
, pp. 6473-6481
-
-
Inohara, N.1
Nunez, G.2
-
55
-
-
0038624558
-
Nods: Intracellular proteins involved in inflammation and apoptosis
-
Inohara N., Nunez G. Nods. intracellular proteins involved in inflammation and apoptosis Nat. Rev. Immunol. 3:2003;371-382
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 371-382
-
-
Inohara, N.1
Nunez, G.2
-
56
-
-
0030745449
-
Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever
-
The International FMF Consortium Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. Cell. 90:1997;797-807
-
(1997)
Cell
, vol.90
, pp. 797-807
-
-
International Fmf Consortium, T.1
-
57
-
-
0034658130
-
ATP-activated oligomerization as a mechanism for apoptosis regulation: Fold and mechanism prediction for CED-4
-
Jaroszewski L., Rychlewski L., Reed J.C., Godzik A. ATP-activated oligomerization as a mechanism for apoptosis regulation. fold and mechanism prediction for CED-4 Proteins. 39:2000;197-203
-
(2000)
Proteins
, vol.39
, pp. 197-203
-
-
Jaroszewski, L.1
Rychlewski, L.2
Reed, J.C.3
Godzik, A.4
-
58
-
-
0041731979
-
Regulation of the expression and processing of caspase-12
-
Kalai M., Lamkanfi M., Denecker G., Boogmans M., Lippens S., Meeus A., Declercq W., Vandenabeele P. Regulation of the expression and processing of caspase-12. J. Cell Biol. 162:2003;457-467
-
(2003)
J. Cell Biol.
, vol.162
, pp. 457-467
-
-
Kalai, M.1
Lamkanfi, M.2
Denecker, G.3
Boogmans, M.4
Lippens, S.5
Meeus, A.6
Declercq, W.7
Vandenabeele, P.8
-
59
-
-
0025182760
-
Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha
-
Kobayashi Y., Yamamoto K., Saido T., Kawasaki H., Oppenheim J.J., Matsushima K. Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha. Proc. Natl. Acad. Sci. USA. 87:1990;5548-5552
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5548-5552
-
-
Kobayashi, Y.1
Yamamoto, K.2
Saido, T.3
Kawasaki, H.4
Oppenheim, J.J.5
Matsushima, K.6
-
60
-
-
0027718173
-
Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats
-
Kobe B., Deisenhofer J. Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature. 366:1993;751-756
-
(1993)
Nature
, vol.366
, pp. 751-756
-
-
Kobe, B.1
Deisenhofer, J.2
-
61
-
-
0035692811
-
The leucine-rich repeat as a protein recognition motif
-
Kobe B., Kajava A.V. The leucine-rich repeat as a protein recognition motif. Curr. Opin. Struct. Biol. 11:2001;725-732
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 725-732
-
-
Kobe, B.1
Kajava, A.V.2
-
62
-
-
0002928890
-
Identification of a monocyte specific pre-interleukin 1 beta convertase activity
-
Kostura M.J., Tocci M.J., Limjuco G., Chin J., Cameron P., Hillman A.G., Chartrain N.A., Schmidt J.A. Identification of a monocyte specific pre-interleukin 1 beta convertase activity. Proc. Natl. Acad. Sci. USA. 86:1989;5227-5231
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5227-5231
-
-
Kostura, M.J.1
Tocci, M.J.2
Limjuco, G.3
Chin, J.4
Cameron, P.5
Hillman, A.G.6
Chartrain, N.A.7
Schmidt, J.A.8
-
63
-
-
0035884195
-
Targeting of the transcription factor Max during apoptosis: Phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1
-
Krippner-Heidenreich A., Talanian R.V., Sekul R., Kraft R., Thole H., Ottleben H., Luscher B. Targeting of the transcription factor Max during apoptosis. phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1 Biochem. J. 358:2001;705-715
-
(2001)
Biochem. J.
, vol.358
, pp. 705-715
-
-
Krippner-Heidenreich, A.1
Talanian, R.V.2
Sekul, R.3
Kraft, R.4
Thole, H.5
Ottleben, H.6
Luscher, B.7
-
64
-
-
0037791779
-
Humoral links between sleep and the immune system: Research issues
-
Krueger J.M., Majde J.A. Humoral links between sleep and the immune system. research issues Ann. N Y Acad. Sci. 992:2003;9-20
-
(2003)
Ann. N Y Acad. Sci.
, vol.992
, pp. 9-20
-
-
Krueger, J.M.1
Majde, J.A.2
-
65
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
-
Kuida K., Lippke J.A., Ku G., Harding M.W., Livingston D.J., Su M.S., Flavell R.A. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science. 267:1995;2000-2003
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
Lippke, J.A.2
Ku, G.3
Harding, M.W.4
Livingston, D.J.5
Su, M.S.6
Flavell, R.A.7
-
66
-
-
0037096207
-
Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response
-
Labasi J.M., Petrushova N., Donovan C., McCurdy S., Lira P., Payette M.M., Brissette W., Wicks J.R., Audoly L., Gabel C.A. Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response. J. Immunol. 168:2002;6436-6445
-
(2002)
J. Immunol.
, vol.168
, pp. 6436-6445
-
-
Labasi, J.M.1
Petrushova, N.2
Donovan, C.3
McCurdy, S.4
Lira, P.5
Payette, M.M.6
Brissette, W.7
Wicks, J.R.8
Audoly, L.9
Gabel, C.A.10
-
67
-
-
0036312069
-
Alice in caspase land. A phylogenetic analysis of caspases from worm to man
-
Lamkanfi M., Declercq W., Kalai M., Saelens X., Vandenabeele P. Alice in caspase land. A phylogenetic analysis of caspases from worm to man. Cell Death Differ. 9:2002;358-361
-
(2002)
Cell Death Differ.
, vol.9
, pp. 358-361
-
-
Lamkanfi, M.1
Declercq, W.2
Kalai, M.3
Saelens, X.4
Vandenabeele, P.5
-
68
-
-
0037162833
-
Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization
-
Lassus P., Opitz-Araya X., Lazebnik Y. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science. 297:2002;1352-1354
-
(2002)
Science
, vol.297
, pp. 1352-1354
-
-
Lassus, P.1
Opitz-Araya, X.2
Lazebnik, Y.3
-
69
-
-
0035860780
-
Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing
-
Lee S.H., Stehlik C., Reed J.C. Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing. J. Biol. Chem. 276:2001;34495-34500
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34495-34500
-
-
Lee, S.H.1
Stehlik, C.2
Reed, J.C.3
-
70
-
-
0028984948
-
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
-
Li P., Allen H., Banerjee S., Franklin S., Herzog L., Johnston C., McDowell J., Paskind M., Rodman L., Salfeld J., et al. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell. 80:1995;401-411
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
-
71
-
-
0042386425
-
The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
-
Liepinsh E., Barbals R., Dahl E., Sharipo A., Staub E., Otting G. The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition. J. Mol. Biol. 332:2003;1155-1163
-
(2003)
J. Mol. Biol.
, vol.332
, pp. 1155-1163
-
-
Liepinsh, E.1
Barbals, R.2
Dahl, E.3
Sharipo, A.4
Staub, E.5
Otting, G.6
-
72
-
-
0034704161
-
Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma
-
Lin X.Y., Choi M.S., Porter A.G. Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma. J. Biol. Chem. 275:2000;39920-39926
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39920-39926
-
-
Lin, X.Y.1
Choi, M.S.2
Porter, A.G.3
-
73
-
-
0035655395
-
Rapid secretion of interleukin-1beta by microvesicle shedding
-
MacKenzie A., Wilson H.L., Kiss-Toth E., Dower S.K., North R.A., Surprenant A. Rapid secretion of interleukin-1beta by microvesicle shedding. Immunity. 15:2001;825-835
-
(2001)
Immunity
, vol.15
, pp. 825-835
-
-
MacKenzie, A.1
Wilson, H.L.2
Kiss-Toth, E.3
Dower, S.K.4
North, R.A.5
Surprenant, A.6
-
74
-
-
0022364132
-
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs
-
March C.J., Mosley B., Larsen A., Cerretti D.P., Braedt G., Price V., Gillis S., Henney C.S., Kronheim S.R., Grabstein K., et al. Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs. Nature. 315:1985;641-647
-
(1985)
Nature
, vol.315
, pp. 641-647
-
-
March, C.J.1
Mosley, B.2
Larsen, A.3
Cerretti, D.P.4
Braedt, G.5
Price, V.6
Gillis, S.7
Henney, C.S.8
Kronheim, S.R.9
Grabstein, K.10
-
75
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F., Burns K., Tschopp J. The inflammasome. a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta Mol. Cell. 10:2002;417-426
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
76
-
-
0033607768
-
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
-
Masumoto J., Taniguchi S., Ayukawa K., Sarvotham H., Kishino T., Niikawa N., Hidaka E., Katsuyama T., Higuchi T., Sagara J. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J. Biol. Chem. 274:1999;33835-33838
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33835-33838
-
-
Masumoto, J.1
Taniguchi, S.2
Ayukawa, K.3
Sarvotham, H.4
Kishino, T.5
Niikawa, N.6
Hidaka, E.7
Katsuyama, T.8
Higuchi, T.9
Sagara, J.10
-
77
-
-
0037423284
-
Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development
-
Masumoto J., Zhou W., Chen F.F., Su F., Kuwada J.Y., Hidaka E., Katsuyama T., Sagara J., Taniguchi S., Ngo-Hazelett P., et al. Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development. J. Biol. Chem. 278:2003;4268-4276
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4268-4276
-
-
Masumoto, J.1
Zhou, W.2
Chen, F.F.3
Su, F.4
Kuwada, J.Y.5
Hidaka, E.6
Katsuyama, T.7
Sagara, J.8
Taniguchi, S.9
Ngo-Hazelett, P.10
-
79
-
-
0033696045
-
An autosomal dominant periodic fever associated with AA amyloidosis in a north Indian family maps to distal chromosome 1q
-
McDermott M.F., Aganna E., Hitman G.A., Ogunkolade B.W., Booth D.R., Hawkins P.N. An autosomal dominant periodic fever associated with AA amyloidosis in a north Indian family maps to distal chromosome 1q. Arthritis Rheum. 43:2000;2034-2040
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 2034-2040
-
-
McDermott, M.F.1
Aganna, E.2
Hitman, G.A.3
Ogunkolade, B.W.4
Booth, D.R.5
Hawkins, P.N.6
-
80
-
-
17944372335
-
CARD15 mutations in Blau syndrome
-
Miceli-Richard C., Lesage S., Rybojad M., Prieur A.M., Manouvrier-Hanu S., Hafner R., Chamaillard M., Zouali H., Thomas G., Hugot J.P. CARD15 mutations in Blau syndrome. Nat. Genet. 29:2001;19-20
-
(2001)
Nat. Genet.
, vol.29
, pp. 19-20
-
-
Miceli-Richard, C.1
Lesage, S.2
Rybojad, M.3
Prieur, A.M.4
Manouvrier-Hanu, S.5
Hafner, R.6
Chamaillard, M.7
Zouali, H.8
Thomas, G.9
Hugot, J.P.10
-
81
-
-
0037160117
-
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
-
Micheau O., Thome M., Schneider P., Holler N., Tschopp J., Nicholson D.W., Briand C., Grutter M.G. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J. Biol. Chem. 277:2002;45162-45171
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45162-45171
-
-
Micheau, O.1
Thome, M.2
Schneider, P.3
Holler, N.4
Tschopp, J.5
Nicholson, D.W.6
Briand, C.7
Grutter, M.G.8
-
82
-
-
0027327223
-
Purification and characterization of active human interleukin-1 beta-converting enzyme from THP.1 monocytic cells
-
Miller D.K., Ayala J.M., Egger L.A., Raju S.M., Yamin T.T., Ding G.J., Gaffney E.P., Howard A.D., Palyha O.C., Rolando A.M., et al. Purification and characterization of active human interleukin-1 beta-converting enzyme from THP.1 monocytic cells. J. Biol. Chem. 268:1993;18062-18069
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18062-18069
-
-
Miller, D.K.1
Ayala, J.M.2
Egger, L.A.3
Raju, S.M.4
Yamin, T.T.5
Ding, G.J.6
Gaffney, E.P.7
Howard, A.D.8
Palyha, O.C.9
Rolando, A.M.10
-
83
-
-
0027449187
-
Induction of apoptosis in fibroblasts by IL-1beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
-
Miura M., Zhu H., Rotello R., Hartwieg E.A., Yuan J. Induction of apoptosis in fibroblasts by IL-1beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell. 75:1993;653-660
-
(1993)
Cell
, vol.75
, pp. 653-660
-
-
Miura, M.1
Zhu, H.2
Rotello, R.3
Hartwieg, E.A.4
Yuan, J.5
-
84
-
-
0037072937
-
An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12
-
Morishima N., Nakanishi K., Takenouchi H., Shibata T., Yasuhiko Y. An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J. Biol. Chem. 277:2002;34287-34294
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34287-34294
-
-
Morishima, N.1
Nakanishi, K.2
Takenouchi, H.3
Shibata, T.4
Yasuhiko, Y.5
-
85
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature. 403:2000;98-103
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
86
-
-
0032969563
-
Aaa+ a class of chaperone-like atpases associated with the assembly, operation, and disassembly of protein complexes
-
Neuwald A.F., Aravind L., Spouge J.L., Koonin E.V. Aaa+. A class of chaperone-like atpases associated with the assembly, operation, and disassembly of protein complexes Genome Res. 9:1999;27-43
-
(1999)
Genome Res.
, vol.9
, pp. 27-43
-
-
Neuwald, A.F.1
Aravind, L.2
Spouge, J.L.3
Koonin, E.V.4
-
87
-
-
0032785021
-
Caspase structure, proteolytic substrates, and function during apoptotic cell death
-
Nicholson D.W. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ. 6:1999;1028-1042
-
(1999)
Cell Death Differ.
, vol.6
, pp. 1028-1042
-
-
Nicholson, D.W.1
-
88
-
-
0036788971
-
Molecular physiology of P2X receptors
-
North R.A. Molecular physiology of P2X receptors. Physiol. Rev. 82:2002;1013-1067
-
(2002)
Physiol. Rev.
, vol.82
, pp. 1013-1067
-
-
North, R.A.1
-
89
-
-
0346350694
-
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties
-
O'Connor W. Jr., Harton J.A., Zhu X., Linhoff M.W., Ting J.P. Cutting edge. CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties J. Immunol. 171:2003;6329-6333
-
(2003)
J. Immunol.
, vol.171
, pp. 6329-6333
-
-
O'connor Jr., W.1
Harton, J.A.2
Zhu, X.3
Linhoff, M.W.4
Ting, J.P.5
-
90
-
-
0034885052
-
AAA+ superfamily ATPases: Common structure-diverse function
-
Ogura T., Wilkinson A.J. AAA+ superfamily ATPases. common structure-diverse function Genes Cells. 6:2001;575-597
-
(2001)
Genes Cells
, vol.6
, pp. 575-597
-
-
Ogura, T.1
Wilkinson, A.J.2
-
91
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
a
-
Ogura Y., Bonen D.K., Inohara N., Nicolae D.L., Chen F.F., Ramos R., Britton H., Moran T., Karaliuskas R., Duerr R.H., et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature. 411:2001;603-606. a
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
-
92
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
-
b
-
Ogura Y., Inohara N., Benito A., Chen F.F., Yamaoka S., Nunez G. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J. Biol. Chem. 276:2001;4812-4818. b
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
Inohara, N.2
Benito, A.3
Chen, F.F.4
Yamaoka, S.5
Nunez, G.6
-
93
-
-
1642633791
-
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
-
Ohtsuka T., Ryu H., Minamishima Y.A., Macip S., Sagara J., Nakayama K.I., Aaronson S.A., Lee S.W. ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway. Nat. Cell Biol. 6:2004;121-128
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 121-128
-
-
Ohtsuka, T.1
Ryu, H.2
Minamishima, Y.A.3
MacIp, S.4
Sagara, J.5
Nakayama, K.I.6
Aaronson, S.A.7
Lee, S.W.8
-
94
-
-
0035943736
-
TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer
-
Pathan N., Marusawa H., Krajewska M., Matsuzawa S., Kim H., Okada K., Torii S., Kitada S., Krajewski S., Welsh K., et al. TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer. J. Biol. Chem. 276:2001;32220-32229
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 32220-32229
-
-
Pathan, N.1
Marusawa, H.2
Krajewska, M.3
Matsuzawa, S.4
Kim, H.5
Okada, K.6
Torii, S.7
Kitada, S.8
Krajewski, S.9
Welsh, K.10
-
95
-
-
0035958867
-
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
-
Poyet J.L., Srinivasula S.M., Tnani M., Razmara M., Fernandes-Alnemri T., Alnemri E.S. Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J. Biol. Chem. 276:2001;28309-28313
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28309-28313
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Tnani, M.3
Razmara, M.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
96
-
-
0037077254
-
Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway
-
Rao R.V., Castro-Obregon S., Frankowski H., Schuler M., Stoka V., del Rio G., Bredesen D.E., Ellerby H.M. Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J. Biol. Chem. 277:2002;21836-21842
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21836-21842
-
-
Rao, R.V.1
Castro-Obregon, S.2
Frankowski, H.3
Schuler, M.4
Stoka, V.5
Del Rio, G.6
Bredesen, D.E.7
Ellerby, H.M.8
-
97
-
-
0037134457
-
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
-
Razmara M., Srinivasula S.M., Wang L., Poyet J.L., Geddes B.J., DiStefano P.S., Bertin J., Alnemri E.S. CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis. J. Biol. Chem. 277:2002;13952-13958
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13952-13958
-
-
Razmara, M.1
Srinivasula, S.M.2
Wang, L.3
Poyet, J.L.4
Geddes, B.J.5
Distefano, P.S.6
Bertin, J.7
Alnemri, E.S.8
-
98
-
-
0033573020
-
Caspase-9 and APAF-1 form an active holoenzyme
-
Rodriguez J., Lazebnik Y. Caspase-9 and APAF-1 form an active holoenzyme. Genes Dev. 13:1999;3179-3184
-
(1999)
Genes Dev.
, vol.13
, pp. 3179-3184
-
-
Rodriguez, J.1
Lazebnik, Y.2
-
99
-
-
0031438499
-
The role of interleukin 1 in acute neurodegeneration and stroke: Pathophysiological and therapeutic implications
-
Rothwell N., Allan S., Toulmond S. The role of interleukin 1 in acute neurodegeneration and stroke. pathophysiological and therapeutic implications J. Clin. Invest. 100:1997;2648-2652
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2648-2652
-
-
Rothwell, N.1
Allan, S.2
Toulmond, S.3
-
100
-
-
2342457148
-
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
-
Saleh M., Vaillancourt J.P., Graham R.K., Huyck M., Srinivasula S.M., Alnemri E.S., Steinberg M.H., Nolan V., Baldwin C.T., Hotchkiss R.S., et al. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature. 429:2004;75-79
-
(2004)
Nature
, vol.429
, pp. 75-79
-
-
Saleh, M.1
Vaillancourt, J.P.2
Graham, R.K.3
Huyck, M.4
Srinivasula, S.M.5
Alnemri, E.S.6
Steinberg, M.H.7
Nolan, V.8
Baldwin, C.T.9
Hotchkiss, R.S.10
-
101
-
-
0037380628
-
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity
-
Salmena L., Lemmers B., Hakem A., Matysiak-Zablocki E., Murakami K., Au P.Y., Berry D.M., Tamblyn L., Shehabeldin A., Migon E., et al. Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Genes Dev. 17:2003;883-895
-
(2003)
Genes Dev.
, vol.17
, pp. 883-895
-
-
Salmena, L.1
Lemmers, B.2
Hakem, A.3
Matysiak-Zablocki, E.4
Murakami, K.5
Au, P.Y.6
Berry, D.M.7
Tamblyn, L.8
Shehabeldin, A.9
Migon, E.10
-
102
-
-
0035932121
-
Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity
-
Samad T.A., Moore K.A., Sapirstein A., Billet S., Allchorne A., Poole S., Bonventre J.V., Woolf C.J. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature. 410:2001;471-475
-
(2001)
Nature
, vol.410
, pp. 471-475
-
-
Samad, T.A.1
Moore, K.A.2
Sapirstein, A.3
Billet, S.4
Allchorne, A.5
Poole, S.6
Bonventre, J.V.7
Woolf, C.J.8
-
104
-
-
0031973493
-
Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells
-
Schumann R.R., Belka C., Reuter D., Lamping N., Kirschning C.J., Weber J.R., Pfeil D. Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells. Blood. 91:1998;577-584
-
(1998)
Blood
, vol.91
, pp. 577-584
-
-
Schumann, R.R.1
Belka, C.2
Reuter, D.3
Lamping, N.4
Kirschning, C.J.5
Weber, J.R.6
Pfeil, D.7
-
105
-
-
0344417114
-
Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype
-
Schwartz S. Jr., Yamamoto H., Navarro M., Maestro M., Reventos J., Perucho M. Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype. Cancer Res. 59:1999;2995-3002
-
(1999)
Cancer Res.
, vol.59
, pp. 2995-3002
-
-
Schwartz Jr., S.1
Yamamoto, H.2
Navarro, M.3
Maestro, M.4
Reventos, J.5
Perucho, M.6
-
106
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol. Cell. 9:2002;459-470
-
(2002)
Mol. Cell
, vol.9
, pp. 459-470
-
-
Shi, Y.1
-
107
-
-
0036079120
-
ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils
-
Shiohara M., Taniguchi S., Masumoto J., Yasui K., Koike K., Komiyama A., Sagara J. ASC, which is composed of a PYD and a CARD, is up-regulated by inflammation and apoptosis in human neutrophils. Biochem. Biophys. Res. Commun. 293:2002;1314-1318
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 1314-1318
-
-
Shiohara, M.1
Taniguchi, S.2
Masumoto, J.3
Yasui, K.4
Koike, K.5
Komiyama, A.6
Sagara, J.7
-
108
-
-
0344823965
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
Shoham N.G., Centola M., Mansfield E., Hull K.M., Wood G., Wise C.A., Kastner D.L. Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. Proc. Natl. Acad. Sci. USA. 100:2003;13501-13506
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
Centola, M.2
Mansfield, E.3
Hull, K.M.4
Wood, G.5
Wise, C.A.6
Kastner, D.L.7
-
109
-
-
0035808396
-
Altered cytokine production in mice lacking P2X(7) receptors
-
Solle M., Labasi J., Perregaux D.G., Stam E., Petrushova N., Koller B.H., Griffiths R.J., Gabel C.A. Altered cytokine production in mice lacking P2X(7) receptors. J. Biol. Chem. 276:2001;125-132
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 125-132
-
-
Solle, M.1
Labasi, J.2
Perregaux, D.G.3
Stam, E.4
Petrushova, N.5
Koller, B.H.6
Griffiths, R.J.7
Gabel, C.A.8
-
110
-
-
0035933536
-
Common and contrasting themes of plant and animal diseases
-
Staskawicz B.J., Mudgett M.B., Dangl J.L., Galan J.E. Common and contrasting themes of plant and animal diseases. Science. 292:2001;2285-2289
-
(2001)
Science
, vol.292
, pp. 2285-2289
-
-
Staskawicz, B.J.1
Mudgett, M.B.2
Dangl, J.L.3
Galan, J.E.4
-
111
-
-
0038682430
-
The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappaB and pro-caspase-1 regulation
-
Stehlik C., Krajewska M., Welsh K., Krajewski S., Godzik A., Reed J.C. The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappaB and pro-caspase-1 regulation. Biochem. J. 373:2003;101-113
-
(2003)
Biochem. J.
, vol.373
, pp. 101-113
-
-
Stehlik, C.1
Krajewska, M.2
Welsh, K.3
Krajewski, S.4
Godzik, A.5
Reed, J.C.6
-
112
-
-
0036257305
-
Genomic organization of the interleukin-1 locus
-
Taylor S.L., Renshaw B.R., Garka K.E., Smith D.E., Sims J.E. Genomic organization of the interleukin-1 locus. Genomics. 79:2002;726-733
-
(2002)
Genomics
, vol.79
, pp. 726-733
-
-
Taylor, S.L.1
Renshaw, B.R.2
Garka, K.E.3
Smith, D.E.4
Sims, J.E.5
-
113
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
Thornberry N.A., Bull H.G., Calaycay J.R., Chapman K.T., Howard A.D., Kostura M.J., Miller D.K., Molineaux S.M., Weidner J.R., Aunins J., et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature. 356:1992;768-774
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
-
114
-
-
2442453730
-
The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress
-
Tinel A., Tschopp J. The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress. Science. 304:2004;843-846
-
(2004)
Science
, vol.304
, pp. 843-846
-
-
Tinel, A.1
Tschopp, J.2
-
115
-
-
0033757582
-
Mater, a maternal effect gene required for early embryonic development in mice
-
Tong Z.B., Gold L., Pfeifer K.E., Dorward H., Lee E., Bondy C.A., Dean J., Nelson L.M. Mater, a maternal effect gene required for early embryonic development in mice. Nat. Genet. 26:2000;267-268
-
(2000)
Nat. Genet.
, vol.26
, pp. 267-268
-
-
Tong, Z.B.1
Gold, L.2
Pfeifer, K.E.3
Dorward, H.4
Lee, E.5
Bondy, C.A.6
Dean, J.7
Nelson, L.M.8
-
116
-
-
0034879132
-
The spectrum of Familial Mediterranean Fever (FMF) mutations
-
Touitou I. The spectrum of Familial Mediterranean Fever (FMF) mutations. Eur. J. Hum. Genet. 9:2001;473-483
-
(2001)
Eur. J. Hum. Genet.
, vol.9
, pp. 473-483
-
-
Touitou, I.1
-
118
-
-
0037851027
-
P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1beta release
-
Verhoef P.A., Estacion M., Schilling W., Dubyak G.R. P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1beta release. J. Immunol. 170:2003;5728-5738
-
(2003)
J. Immunol.
, vol.170
, pp. 5728-5738
-
-
Verhoef, P.A.1
Estacion, M.2
Schilling, W.3
Dubyak, G.R.4
-
119
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
Wang S., Miura M., Jung Y.K., Zhu H., Li E., Yuan J. Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell. 92:1998;501-509
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.K.3
Zhu, H.4
Li, E.5
Yuan, J.6
-
120
-
-
0010464874
-
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing
-
Wang L., Manji G.A., Grenier J.M., Al-Garawi A., Merriam S., Lora J.M., Geddes B.J., Briskin M., DiStefano P.S., Bertin J. PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing. J. Biol. Chem. 277:2002;29874-29880
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29874-29880
-
-
Wang, L.1
Manji, G.A.2
Grenier, J.M.3
Al-Garawi, A.4
Merriam, S.5
Lora, J.M.6
Geddes, B.J.7
Briskin, M.8
Distefano, P.S.9
Bertin, J.10
-
121
-
-
0033561546
-
Endotoxin-stimulated monocytes release multiple forms of IL-1 beta, including a proIL-1 beta form whose detection is affected by export
-
Wewers M.D., Winnard A.V., Dare H.A. Endotoxin-stimulated monocytes release multiple forms of IL-1 beta, including a proIL-1 beta form whose detection is affected by export. J. Immunol. 162:1999;4858-4863
-
(1999)
J. Immunol.
, vol.162
, pp. 4858-4863
-
-
Wewers, M.D.1
Winnard, A.V.2
Dare, H.A.3
-
122
-
-
0035957929
-
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
-
Yoneda T., Imaizumi K., Oono K., Yui D., Gomi F., Katayama T., Tohyama M. Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J. Biol. Chem. 276:2001;13935-13940
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13935-13940
-
-
Yoneda, T.1
Imaizumi, K.2
Oono, K.3
Yui, D.4
Gomi, F.5
Katayama, T.6
Tohyama, M.7
-
123
-
-
0027223912
-
Familial cold urticaria
-
Zip C.M., Ross J.B., Greaves M.W., Scriver C.R., Mitchell J.J., Zoar S. Familial cold urticaria. Clin. Exp. Dermatol. 18:1993;338-341
-
(1993)
Clin. Exp. Dermatol.
, vol.18
, pp. 338-341
-
-
Zip, C.M.1
Ross, J.B.2
Greaves, M.W.3
Scriver, C.R.4
Mitchell, J.J.5
Zoar, S.6
-
124
-
-
0037810844
-
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
-
Zong W.X., Li C., Hatzivassiliou G., Lindsten T., Yu Q.C., Yuan J., Thompson C.B. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J. Cell Biol. 162:2003;59-69
-
(2003)
J. Cell Biol.
, vol.162
, pp. 59-69
-
-
Zong, W.X.1
Li, C.2
Hatzivassiliou, G.3
Lindsten, T.4
Yu, Q.C.5
Yuan, J.6
Thompson, C.B.7
-
125
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou H., Henzel W.J., Liu X., Lutschg A., Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell. 90:1997;405-413
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
|