The Nlrp3 inflammasome is critical for aluminum hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity

European Journal of Immunology

Volumn 38, Issue 8, 2008, Pages 2085-2089

  Franchi, Luigi ^a   Núñez, Gabriel ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Adjuvant; Aluminum hydroxide; Caspase 1; NOD like receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALUMINUM HYDROXIDE; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN; AUTACOID; CASPASE RECRUITMENT DOMAIN PROTEIN 4; CELL PROTEIN; CYTOKINE; HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN G; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; PROTEIN NLRP3; PYRIN DOMAIN CONTAINING 3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; IMMUNOLOGICAL ADJUVANT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; IMMUNIZATION; IMMUNOBLOTTING; IMMUNOGLOBULIN BLOOD LEVEL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DOMAIN; PROTEIN FAMILY; ANIMAL; DRUG EFFECT; IMMUNOLOGY; INFLAMMATION; METABOLISM; PHYSIOLOGY; SECRETION;

ADJUVANTS, IMMUNOLOGIC; ALUMINUM HYDROXIDE; ANIMALS; CARRIER PROTEINS; CASPASE 1; ENZYME ACTIVATION; INFLAMMATION; INTERLEUKIN-1BETA; MICE;

EID: 50849112477     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200838549     Document Type: Article

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