Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

Journal of Experimental Medicine

Volumn 205, Issue 4, 2008, Pages 869-882

  Kool, Mirjam ^a   Soullié, Thomas ^a   Van Nimwegen, Menno ^a   Willart, Monique A M ^a,b   Muskens, Femke ^a   Jung, Steffen ^c   Hoogsteden, Henk C ^a   Hammad, Hamida ^a,b   Lambrecht, Bart N ^a,b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM HYDROXIDE; CD11 ANTIGEN; MYELOID DIFFERENTIATION FACTOR 88; OVALBUMIN; URATE OXIDASE; URIC ACID;

ADAPTIVE IMMUNITY; ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; DRUG MECHANISM; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOGENICITY; LYMPH NODE; MONOCYTE; MOUSE; NONHUMAN; PERITONEUM; PRIORITY JOURNAL; TH2 CELL;

ADJUVANTS, IMMUNOLOGIC; ALUM COMPOUNDS; ANIMALS; ANTIBODY FORMATION; ANTIGEN PRESENTATION; ANTIGENS; ANTIGENS, CD11C; CELL MOVEMENT; CROSS-PRIMING; DENDRITIC CELLS; IMMUNITY; IMMUNITY, NATURAL; INFLAMMATION; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAPERITONEAL; LYMPH NODES; MICE; MONOCYTES; MYELOID DIFFERENTIATION FACTOR 88; OVALBUMIN; SIGNAL TRANSDUCTION; URIC ACID;

EID: 42249088234     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20071087     Document Type: Article

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