The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Nature Immunology

Volumn 5, Issue 7, 2004, Pages 730-737

  Yoneyama, Mitsutoshi ^a   Kikuchi, Mika ^a   Natsukawa, Takashi ^a   Shinobu, Noriaki ^a   Imaizumi, Tadaatsu ^b   Miyagishi, Makoto ^c   Taira, Kazunari ^c   Akira, Shizuo ^d   Fujita, Takashi ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CASPASE; DOUBLE STRANDED RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 3; REGULATOR PROTEIN; RNA HELICASE; DNA BINDING PROTEIN; IRF3 PROTEIN, HUMAN; IRF3 PROTEIN, MOUSE; MESSENGER RNA; PROTEIN; RAI1 PROTEIN, HUMAN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; GENE ACTIVATION; GENETIC CODE; HUMAN; HUMAN CELL; INTERFERON PRODUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; RNA ANALYSIS; SIGNAL TRANSDUCTION; VIRUS GENE; VIRUS IMMUNITY; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PROMOTER REGION; PROTEIN TERTIARY STRUCTURE; REPORTER GENE; TUMOR CELL LINE; VIRUS;

ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERONS; MICE; NF-KAPPA B; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; PROTEINS; RNA HELICASES; RNA, DOUBLE-STRANDED; RNA, MESSENGER; RNA, SMALL INTERFERING; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; VIRUSES;

EID: 3242813113     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1087     Document Type: Article

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