메뉴 건너뛰기




Volumn 7, Issue 5, 2007, Pages 404-408

New aspects of the molecular basis of contact allergy

Author keywords

Dendritic cells; Haptens; Skin; T regulatory cells

Indexed keywords

HAPTEN;

EID: 34548691004     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0b013e3282ef6923     Document Type: Review
Times cited : (46)

References (47)
  • 1
    • 27144479286 scopus 로고    scopus 로고
    • Hapten-protein binding: From theory to practical application in the in vitro prediction of skin sensitization
    • Divkovic M, Pease CK, Gerberick GF, Basketter DA. Hapten-protein binding: from theory to practical application in the in vitro prediction of skin sensitization. Contact Dermatitis 2005; 53:189-200.
    • (2005) Contact Dermatitis , vol.53 , pp. 189-200
    • Divkovic, M.1    Pease, C.K.2    Gerberick, G.F.3    Basketter, D.A.4
  • 2
    • 0030691083 scopus 로고    scopus 로고
    • Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules
    • Aiba S, Terunuma A, Manome H, Tagami H. Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules. Eur J Immunol 1997; 27:3031-3038.
    • (1997) Eur J Immunol , vol.27 , pp. 3031-3038
    • Aiba, S.1    Terunuma, A.2    Manome, H.3    Tagami, H.4
  • 3
    • 0035869634 scopus 로고    scopus 로고
    • A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers
    • Arrighi JF, Rebsamen M, Rousset F, et al. A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers. J Immunol 2001; 166:3837-3845.
    • (2001) J Immunol , vol.166 , pp. 3837-3845
    • Arrighi, J.F.1    Rebsamen, M.2    Rousset, F.3
  • 4
    • 0033103667 scopus 로고    scopus 로고
    • Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity
    • Kehren J, Desvignes C, Krasteva M, et al. Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity. J Exp Med 1999; 189:779-786.
    • (1999) J Exp Med , vol.189 , pp. 779-786
    • Kehren, J.1    Desvignes, C.2    Krasteva, M.3
  • 5
    • 0034665309 scopus 로고    scopus 로고
    • Disparate cytotoxic activity of nickel-specific CD8+ and CD4+ T cell subsets against keratinocytes
    • Traidl C, Sebastiani S, Albanesi C, et al. Disparate cytotoxic activity of nickel-specific CD8+ and CD4+ T cell subsets against keratinocytes. J Immunol 2000; 165:3058-3064.
    • (2000) J Immunol , vol.165 , pp. 3058-3064
    • Traidl, C.1    Sebastiani, S.2    Albanesi, C.3
  • 7
    • 0034693950 scopus 로고    scopus 로고
    • Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2
    • Biedermann T, Kneilling M, Mailhammer R, et al. Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2. J Exp Med 2000; 192:1441-1452.
    • (2000) J Exp Med , vol.192 , pp. 1441-1452
    • Biedermann, T.1    Kneilling, M.2    Mailhammer, R.3
  • 8
    • 33645989497 scopus 로고    scopus 로고
    • T cell- and B cell-independent adaptive immunity mediated by natural killer cells
    • NK cells are new unexpected protagonists of hapten hypersensitivity. Although mechanisms involved in NK recognition of the hapten determinants are undetermined, new perspectives in the field of skin allergies are explored in this article
    • O'Leary JG, Goodarzi M, Drayton DL, von Andrian UH. T cell- and B cell-independent adaptive immunity mediated by natural killer cells. Nat Immunol 2006; 7:507-516. NK cells are new unexpected protagonists of hapten hypersensitivity. Although mechanisms involved in NK recognition of the hapten determinants are undetermined, new perspectives in the field of skin allergies are explored in this article.
    • (2006) Nat Immunol , vol.7 , pp. 507-516
    • O'Leary, J.G.1    Goodarzi, M.2    Drayton, D.L.3    von Andrian, U.H.4
  • 9
    • 0032964495 scopus 로고    scopus 로고
    • A new paradigm of T cell allergy: Requirement for the B-1 cell subset
    • Askenase PW, Kawikova I, Paliwal V, et al. A new paradigm of T cell allergy: requirement for the B-1 cell subset. Int Arch Allergy Immunol 1999; 118: 145-149.
    • (1999) Int Arch Allergy Immunol , vol.118 , pp. 145-149
    • Askenase, P.W.1    Kawikova, I.2    Paliwal, V.3
  • 10
    • 0036065632 scopus 로고    scopus 로고
    • Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses
    • Redegeld FA, van der Heijden MW, Kool M, et al. Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses. Nat Med 2002; 8: 694-701.
    • (2002) Nat Med , vol.8 , pp. 694-701
    • Redegeld, F.A.1    van der Heijden, M.W.2    Kool, M.3
  • 11
    • 0018866633 scopus 로고
    • Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB
    • Toews GB, Bergstresser PR, Streilein JW. Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J Immunol 1980; 124:445-453.
    • (1980) J Immunol , vol.124 , pp. 445-453
    • Toews, G.B.1    Bergstresser, P.R.2    Streilein, J.W.3
  • 12
    • 33646062612 scopus 로고    scopus 로고
    • Mast cell-associated TNF promotes dendritic cell migration
    • Mast cells have a critical role in cutaneous immune responses to haptens. As a major source of preformed TNF, their activation is required for proper dendritic cell mobilization and maturation during CHS
    • Suto H, Nakae S, Kakurai M, et al. Mast cell-associated TNF promotes dendritic cell migration. J Immunol 2006; 176:4102-4112. Mast cells have a critical role in cutaneous immune responses to haptens. As a major source of preformed TNF, their activation is required for proper dendritic cell mobilization and maturation during CHS.
    • (2006) J Immunol , vol.176 , pp. 4102-4112
    • Suto, H.1    Nakae, S.2    Kakurai, M.3
  • 13
    • 22344443257 scopus 로고    scopus 로고
    • Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity
    • Bennett CL, van Rijn E, Jung S, et al. Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity. J Cell Biol 2005; 169:569-576.
    • (2005) J Cell Biol , vol.169 , pp. 569-576
    • Bennett, C.L.1    van Rijn, E.2    Jung, S.3
  • 14
    • 21144444056 scopus 로고    scopus 로고
    • Dynamics and function of Langerhans cells in vivo: Dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells
    • Kissenpfennig A, Henri S, Dubois B, et al. Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity 2005; 22:643-654.
    • (2005) Immunity , vol.22 , pp. 643-654
    • Kissenpfennig, A.1    Henri, S.2    Dubois, B.3
  • 15
    • 28844492624 scopus 로고    scopus 로고
    • Epidermal Langerhans cell-deficient mice develop enhanced contact hypersensitivity
    • Kaplan DH, Jenison MC, Saeland S, et al. Epidermal Langerhans cell-deficient mice develop enhanced contact hypersensitivity. Immunity 2005; 23:611-620.
    • (2005) Immunity , vol.23 , pp. 611-620
    • Kaplan, D.H.1    Jenison, M.C.2    Saeland, S.3
  • 16
    • 0024317486 scopus 로고
    • Antigen-presenting cells in the induction of contact hypersensitivity in mice: Evidence that Langerhans cells are sufficient but not required
    • Streilein JW. Antigen-presenting cells in the induction of contact hypersensitivity in mice: evidence that Langerhans cells are sufficient but not required. J Invest Dermatol 1989; 93:443-448.
    • (1989) J Invest Dermatol , vol.93 , pp. 443-448
    • Streilein, J.W.1
  • 17
    • 0028824168 scopus 로고
    • Removal of the majority of epidermal Langerhans cells by topical or systemic steroid application enhances the effector phase of murine contact hypersensitivity
    • Grabbe S, Steinbrink K, Steinert M, et al. Removal of the majority of epidermal Langerhans cells by topical or systemic steroid application enhances the effector phase of murine contact hypersensitivity. J Immunol 1995; 155: 4207-4217.
    • (1995) J Immunol , vol.155 , pp. 4207-4217
    • Grabbe, S.1    Steinbrink, K.2    Steinert, M.3
  • 18
    • 0034782362 scopus 로고    scopus 로고
    • The differential fate of cadherins during T-cell-induced keratinocyte apoptosis leads to spongiosis in eczematous dermatitis
    • Trautmann A, Altznauer F, Akdis M, et al. The differential fate of cadherins during T-cell-induced keratinocyte apoptosis leads to spongiosis in eczematous dermatitis. J Invest Dermatol 2001; 117:927-934.
    • (2001) J Invest Dermatol , vol.117 , pp. 927-934
    • Trautmann, A.1    Altznauer, F.2    Akdis, M.3
  • 19
    • 0031804298 scopus 로고    scopus 로고
    • Contact hypersensitivity in MHC class II-deficient mice depends on CD8 T lymphocytes primed by immunostimulating Langerhans cells
    • Bouloc A, Cavani A, Katz SI. Contact hypersensitivity in MHC class II-deficient mice depends on CD8 T lymphocytes primed by immunostimulating Langerhans cells. J Invest Dermatol 1998; 111:44-49.
    • (1998) J Invest Dermatol , vol.111 , pp. 44-49
    • Bouloc, A.1    Cavani, A.2    Katz, S.I.3
  • 20
    • 0031691280 scopus 로고    scopus 로고
    • Patients with allergic contact dermatitis to nickel and nonallergic individuals display different nickel-specific T cell responses: Evidence for the presence of effector CD8+ and regulatory CD4+ T cells
    • Cavani A, Mei D, Guerra E, et al. Patients with allergic contact dermatitis to nickel and nonallergic individuals display different nickel-specific T cell responses: evidence for the presence of effector CD8+ and regulatory CD4+ T cells. J Invest Dermatol 1998; 111:621-628.
    • (1998) J Invest Dermatol , vol.111 , pp. 621-628
    • Cavani, A.1    Mei, D.2    Guerra, E.3
  • 21
    • 0027371652 scopus 로고
    • Predominance of epidermal CD8+ T lymphocytes in bullous cutaneous reactions caused by beta-lactam antibiotics
    • Hertl M, Bohlen H, Jugert F, et al. Predominance of epidermal CD8+ T lymphocytes in bullous cutaneous reactions caused by beta-lactam antibiotics. J Invest Dermatol 1993; 101:794-799.
    • (1993) J Invest Dermatol , vol.101 , pp. 794-799
    • Hertl, M.1    Bohlen, H.2    Jugert, F.3
  • 22
    • 7944234979 scopus 로고    scopus 로고
    • Toxic epidermal necrolysis: Effector cells are drug-specific cytotoxic T cells
    • Nassif A, Bensussan A, Boumsell L, et al. Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells. J Allergy Clin Immunol 2004; 114: 1209-1215.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1209-1215
    • Nassif, A.1    Bensussan, A.2    Boumsell, L.3
  • 23
    • 0034798403 scopus 로고    scopus 로고
    • A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases
    • Albanesi C, Scarponi C, Sebastiani S, et al. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases. J Leukoc Biol 2001; 70:617-623.
    • (2001) J Leukoc Biol , vol.70 , pp. 617-623
    • Albanesi, C.1    Scarponi, C.2    Sebastiani, S.3
  • 24
    • 0031907044 scopus 로고    scopus 로고
    • Interferon-gamma-stimulated human keratinocytes express the genes necessary for the production of peptide-loaded MHC class II molecules
    • Albanesi C, Cavani A, Girolomoni G. Interferon-gamma-stimulated human keratinocytes express the genes necessary for the production of peptide-loaded MHC class II molecules. J Invest Dermatol 1998; 110:138-142.
    • (1998) J Invest Dermatol , vol.110 , pp. 138-142
    • Albanesi, C.1    Cavani, A.2    Girolomoni, G.3
  • 25
    • 0032939560 scopus 로고    scopus 로고
    • IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: Synergistic or antagonist effects with IFN-gamma and TNF-alpha
    • Albanesi C, Cavani A, Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha. J Immunol 1999; 162:494-502.
    • (1999) J Immunol , vol.162 , pp. 494-502
    • Albanesi, C.1    Cavani, A.2    Girolomoni, G.3
  • 26
    • 0036754255 scopus 로고    scopus 로고
    • Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses
    • Nakae S, Komiyama Y, Nambu A, et al. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 2002; 17:375-387.
    • (2002) Immunity , vol.17 , pp. 375-387
    • Nakae, S.1    Komiyama, Y.2    Nambu, A.3
  • 27
    • 33750815930 scopus 로고    scopus 로고
    • He D, Wu L, Kim HK, et al. CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. J Immunol 2006; 177:6852-6858. This article expands our knowledge on the recently characterized IL-17-producing T cells.
    • He D, Wu L, Kim HK, et al. CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. J Immunol 2006; 177:6852-6858. This article expands our knowledge on the recently characterized IL-17-producing T cells.
  • 28
    • 23044478996 scopus 로고    scopus 로고
    • T cells induced by ultraviolet radiation
    • Schwarz T. Regulatory T cells induced by ultraviolet radiation. Int Arch Allergy Immunol 2005; 137:187-193.
    • (2005) Int Arch Allergy Immunol , vol.137 , pp. 187-193
    • Regulatory, S.T.1
  • 31
    • 33746338535 scopus 로고    scopus 로고
    • Interleukin-10- secreting type 1 regulatory T cells in rodents and humans
    • Roncarolo MG, Gregori S, Battaglia M, et al. Interleukin-10- secreting type 1 regulatory T cells in rodents and humans. Immunol Rev 2006; 212:28-50.
    • (2006) Immunol Rev , vol.212 , pp. 28-50
    • Roncarolo, M.G.1    Gregori, S.2    Battaglia, M.3
  • 32
    • 0028086171 scopus 로고
    • In vivo effects of interleukin-10 on contact hypersensitivity and delayed-type hypersensitivity reactions
    • Schwarz A, Grabbe S, Riemann H, et al. In vivo effects of interleukin-10 on contact hypersensitivity and delayed-type hypersensitivity reactions. J Invest Dermatol 1994; 103:211-216.
    • (1994) J Invest Dermatol , vol.103 , pp. 211-216
    • Schwarz, A.1    Grabbe, S.2    Riemann, H.3
  • 33
    • 0028226996 scopus 로고
    • Regulation of contact hypersensitivity by interleukin 10
    • Ferguson TA, Dube P, Griffith TS. Regulation of contact hypersensitivity by interleukin 10. J Exp Med 1994; 179:1597-1604.
    • (1994) J Exp Med , vol.179 , pp. 1597-1604
    • Ferguson, T.A.1    Dube, P.2    Griffith, T.S.3
  • 34
    • 0029035110 scopus 로고
    • Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses
    • Berg DJ, Leach MW, Kuhn R, et al. Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses. J Exp Med 1995; 182:99-108.
    • (1995) J Exp Med , vol.182 , pp. 99-108
    • Berg, D.J.1    Leach, M.W.2    Kuhn, R.3
  • 35
    • 0034045748 scopus 로고    scopus 로고
    • Human CD4+ T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses
    • Cavani A, Nasorri F, Prezzi C, et al. Human CD4+ T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses. J Invest Dermatol 2000; 114:295-302.
    • (2000) J Invest Dermatol , vol.114 , pp. 295-302
    • Cavani, A.1    Nasorri, F.2    Prezzi, C.3
  • 36
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and nonself
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and nonself. Nat Immunol 2005; 6:345-352.
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 37
    • 32944473707 scopus 로고    scopus 로고
    • Induced peripheral regulatory T cells: The family grows larger
    • Hoglund P. Induced peripheral regulatory T cells: the family grows larger. Eur J Immunol 2006; 36:264-266.
    • (2006) Eur J Immunol , vol.36 , pp. 264-266
    • Hoglund, P.1
  • 38
    • 33746379546 scopus 로고    scopus 로고
    • Kim JM, Rudensky A. The role of the transcription factor Foxp3 in the development of regulatory T cells. Immunol Rev 2006; 212:86-98. A good review that summarizes the role of Foxp3 in Treg physiology.
    • Kim JM, Rudensky A. The role of the transcription factor Foxp3 in the development of regulatory T cells. Immunol Rev 2006; 212:86-98. A good review that summarizes the role of Foxp3 in Treg physiology.
  • 39
    • 0142152433 scopus 로고    scopus 로고
    • Innate CD4+CD25+ regulatory T cells are required for oral tolerance and inhibition of CD8+ T cells mediating skin inflammation
    • Dubois B, Chapat L, Goubier A, et al. Innate CD4+CD25+ regulatory T cells are required for oral tolerance and inhibition of CD8+ T cells mediating skin inflammation. Blood 2003; 102:3295-3301.
    • (2003) Blood , vol.102 , pp. 3295-3301
    • Dubois, B.1    Chapat, L.2    Goubier, A.3
  • 40
    • 0029788425 scopus 로고    scopus 로고
    • Lack of oral tolerance but oral priming for contact sensitivity to dinitrofluorobenzene in major histocompatibility complex class II-deficient mice and in CD4+ T cell-depleted mice
    • Desvignes C, Bour H, Nicolas JF, Kaiserlian D. Lack of oral tolerance but oral priming for contact sensitivity to dinitrofluorobenzene in major histocompatibility complex class II-deficient mice and in CD4+ T cell-depleted mice. Eur J Immunol 1996; 26:1756-1761.
    • (1996) Eur J Immunol , vol.26 , pp. 1756-1761
    • Desvignes, C.1    Bour, H.2    Nicolas, J.F.3    Kaiserlian, D.4
  • 41
    • 33645054315 scopus 로고    scopus 로고
    • Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells
    • Elegant paper that focuses on the role of dendritic cells in the induction of oral tolerance
    • Worbs T, Bode U, Yan S, et al. Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells. J Exp Med 2006; 203:519-527. Elegant paper that focuses on the role of dendritic cells in the induction of oral tolerance.
    • (2006) J Exp Med , vol.203 , pp. 519-527
    • Worbs, T.1    Bode, U.2    Yan, S.3
  • 42
    • 32044442305 scopus 로고    scopus 로고
    • Ghoreishi M, Dutz JP. Tolerance induction by transcutaneous immunization through ultraviolet-irradiated skin is transferable through CD4+CD25+ T regulatory cells and is dependent on host-derived IL-10. J Immunol 2006; 176:2635-2644. Although in-vitro CD25+ Treg cells suppress immune responses in a cytokine-independent mechanism, growing evidence exists that IL-10 or transforming growth factor-β are required for immune suppression in vivo.
    • Ghoreishi M, Dutz JP. Tolerance induction by transcutaneous immunization through ultraviolet-irradiated skin is transferable through CD4+CD25+ T regulatory cells and is dependent on host-derived IL-10. J Immunol 2006; 176:2635-2644. Although in-vitro CD25+ Treg cells suppress immune responses in a cytokine-independent mechanism, growing evidence exists that IL-10 or transforming growth factor-β are required for immune suppression in vivo.
  • 43
    • 0034663943 scopus 로고    scopus 로고
    • Evidence for functional relevance of CTLA-4 in ultraviolet-radiation-induced tolerance
    • Schwarz A, Beissert S, Grosse-Heitmeyer K, et al. Evidence for functional relevance of CTLA-4 in ultraviolet-radiation-induced tolerance. J Immunol 2000; 165:1824-1831.
    • (2000) J Immunol , vol.165 , pp. 1824-1831
    • Schwarz, A.1    Beissert, S.2    Grosse-Heitmeyer, K.3
  • 44
    • 0345016451 scopus 로고    scopus 로고
    • Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals
    • Cavani A, Nasorri F, Ottaviani C, et al. Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals. J Immunol 2003; 171:5760-5768.
    • (2003) J Immunol , vol.171 , pp. 5760-5768
    • Cavani, A.1    Nasorri, F.2    Ottaviani, C.3
  • 45
    • 0035903307 scopus 로고    scopus 로고
    • Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells
    • Iellem A, Mariani M, Lang R, et al. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med 2001; 194:847-853.
    • (2001) J Exp Med , vol.194 , pp. 847-853
    • Iellem, A.1    Mariani, M.2    Lang, R.3
  • 46
    • 33846225254 scopus 로고    scopus 로고
    • Alteration of the migratory behavior of UV-induced regulatory T cells by tissue-specific dendritic cells
    • Schwarz A, Maeda A, Schwarz T. Alteration of the migratory behavior of UV-induced regulatory T cells by tissue-specific dendritic cells. J Immunol 2007; 178:877-886.
    • (2007) J Immunol , vol.178 , pp. 877-886
    • Schwarz, A.1    Maeda, A.2    Schwarz, T.3
  • 47
    • 33646131187 scopus 로고    scopus 로고
    • Low zone tolerance induced by systemic application of allergens inhibits Tc1-mediated skin inflammation
    • Seidel-Guyenot W, Perschon S, Dechant N, et al. Low zone tolerance induced by systemic application of allergens inhibits Tc1-mediated skin inflammation. J Allergy Clin Immunol 2006; 117:1170-1177.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 1170-1177
    • Seidel-Guyenot, W.1    Perschon, S.2    Dechant, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.