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Volumn 19, Issue 1, 2007, Pages 24-32

TLR signaling

Author keywords

Innate immunity; Signal transduction; Toll like receptor

Indexed keywords

ADAPTOR PROTEIN; CELL PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 2; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 4; INTERFERON REGULATORY FACTOR 6; INTERFERON REGULATORY FACTOR 7; INTERFERON REGULATORY FACTOR 9; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4;

EID: 33947694370     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.smim.2006.12.004     Document Type: Review
Times cited : (1362)

References (72)
  • 1
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S., Uematsu S., and Takeuchi O. Pathogen recognition and innate immunity. Cell 124 (2006) 783-801
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 2
    • 33746161021 scopus 로고    scopus 로고
    • Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells
    • Uematsu S., Jang M.H., Chevrier N., Guo Z., Kumagai Y., Yamamoto M., et al. Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells. Nat Immunol 7 (2006) 868-874
    • (2006) Nat Immunol , vol.7 , pp. 868-874
    • Uematsu, S.1    Jang, M.H.2    Chevrier, N.3    Guo, Z.4    Kumagai, Y.5    Yamamoto, M.6
  • 3
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S., and Takeda K. Toll-like receptor signalling. Nat Rev Immunol 4 (2004) 499-511
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 4
    • 33748871187 scopus 로고    scopus 로고
    • The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
    • Carty M., Goodbody R., Schroder M., Stack J., Moynagh P.N., and Bowie A.G. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat Immunol 7 (2006) 1074-1081
    • (2006) Nat Immunol , vol.7 , pp. 1074-1081
    • Carty, M.1    Goodbody, R.2    Schroder, M.3    Stack, J.4    Moynagh, P.N.5    Bowie, A.G.6
  • 5
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kappaB pathway
    • Chen Z.J. Ubiquitin signalling in the NF-kappaB pathway. Nat Cell Biol 7 (2005) 758-765
    • (2005) Nat Cell Biol , vol.7 , pp. 758-765
    • Chen, Z.J.1
  • 6
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian E., and Karin M. AP-1 as a regulator of cell life and death. Nat Cell Biol 4 (2002) 131-136
    • (2002) Nat Cell Biol , vol.4 , pp. 131-136
    • Shaulian, E.1    Karin, M.2
  • 7
    • 27544434183 scopus 로고    scopus 로고
    • Essential function for the kinase TAK1 in innate and adaptive immune responses
    • Sato S., Sanjo H., Takeda K., Ninomiya-Tsuji J., Yamamoto M., Kawai T., et al. Essential function for the kinase TAK1 in innate and adaptive immune responses. Nat Immunol 6 (2005) 1087-1095
    • (2005) Nat Immunol , vol.6 , pp. 1087-1095
    • Sato, S.1    Sanjo, H.2    Takeda, K.3    Ninomiya-Tsuji, J.4    Yamamoto, M.5    Kawai, T.6
  • 8
    • 33747615237 scopus 로고    scopus 로고
    • Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
    • Yamamoto M., Okamoto T., Takeda K., Sato S., Sanjo H., Uematsu S., et al. Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling. Nat Immunol 7 (2006) 962-970
    • (2006) Nat Immunol , vol.7 , pp. 962-970
    • Yamamoto, M.1    Okamoto, T.2    Takeda, K.3    Sato, S.4    Sanjo, H.5    Uematsu, S.6
  • 9
    • 0346496017 scopus 로고    scopus 로고
    • Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3
    • Huang Q., Yang J., Lin Y., Walker C., Cheng J., Liu Z.G., et al. Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3. Nat Immunol 5 (2004) 98-103
    • (2004) Nat Immunol , vol.5 , pp. 98-103
    • Huang, Q.1    Yang, J.2    Lin, Y.3    Walker, C.4    Cheng, J.5    Liu, Z.G.6
  • 10
    • 17744371331 scopus 로고    scopus 로고
    • TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
    • Dumitru C.D., Ceci J.D., Tsatsanis C., Kontoyiannis D., Stamatakis K., Lin J.H., et al. TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell 103 (2000) 1071-1083
    • (2000) Cell , vol.103 , pp. 1071-1083
    • Dumitru, C.D.1    Ceci, J.D.2    Tsatsanis, C.3    Kontoyiannis, D.4    Stamatakis, K.5    Lin, J.H.6
  • 12
    • 20644433073 scopus 로고    scopus 로고
    • ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity
    • Matsuzawa A., Saegusa K., Noguchi T., Sadamitsu C., Nishitoh H., Nagai S., et al. ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat Immunol 6 (2005) 587-592
    • (2005) Nat Immunol , vol.6 , pp. 587-592
    • Matsuzawa, A.1    Saegusa, K.2    Noguchi, T.3    Sadamitsu, C.4    Nishitoh, H.5    Nagai, S.6
  • 13
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • Kawai T., Adachi O., Ogawa T., Takeda K., and Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11 (1999) 115-122
    • (1999) Immunity , vol.11 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 14
    • 0035889228 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
    • Kawai T., Takeuchi O., Fujita T., Inoue J., Muhlradt P.F., Sato S., et al. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J Immunol 167 (2001) 5887-5894
    • (2001) J Immunol , vol.167 , pp. 5887-5894
    • Kawai, T.1    Takeuchi, O.2    Fujita, T.3    Inoue, J.4    Muhlradt, P.F.5    Sato, S.6
  • 15
    • 0037114185 scopus 로고    scopus 로고
    • A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
    • Yamamoto M., Sato S., Mori K., Hoshino K., Takeuchi O., Takeda K., et al. A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J Immunol 169 (2002) 6668-6672
    • (2002) J Immunol , vol.169 , pp. 6668-6672
    • Yamamoto, M.1    Sato, S.2    Mori, K.3    Hoshino, K.4    Takeuchi, O.5    Takeda, K.6
  • 16
    • 0037320451 scopus 로고    scopus 로고
    • TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction
    • Oshiumi H., Matsumoto M., Funami K., Akazawa T., and Seya T. TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat Immunol 4 (2003) 161-167
    • (2003) Nat Immunol , vol.4 , pp. 161-167
    • Oshiumi, H.1    Matsumoto, M.2    Funami, K.3    Akazawa, T.4    Seya, T.5
  • 17
    • 0043176281 scopus 로고    scopus 로고
    • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
    • Yamamoto M., Sato S., Hemmi H., Hoshino K., Kaisho T., Sanjo H., et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301 (2003) 640-643
    • (2003) Science , vol.301 , pp. 640-643
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3    Hoshino, K.4    Kaisho, T.5    Sanjo, H.6
  • 18
    • 0042679529 scopus 로고    scopus 로고
    • Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
    • Hoebe K., Du X., Georgel P., Janssen E., Tabeta K., Kim S.O., et al. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424 (2003) 743-748
    • (2003) Nature , vol.424 , pp. 743-748
    • Hoebe, K.1    Du, X.2    Georgel, P.3    Janssen, E.4    Tabeta, K.5    Kim, S.O.6
  • 19
    • 0038363463 scopus 로고    scopus 로고
    • Triggering the interferon antiviral response through an IKK-related pathway
    • Sharma S., tenOever B.R., Grandvaux N., Zhou G.P., Lin R., and Hiscott J. Triggering the interferon antiviral response through an IKK-related pathway. Science 300 (2003) 1148-1151
    • (2003) Science , vol.300 , pp. 1148-1151
    • Sharma, S.1    tenOever, B.R.2    Grandvaux, N.3    Zhou, G.P.4    Lin, R.5    Hiscott, J.6
  • 22
    • 4344566281 scopus 로고    scopus 로고
    • The roles of two IkappaB Kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection
    • Hemmi H., Takeuchi O., Sato S., Yamamoto M., Kaisho T., Sanjo H., et al. The roles of two IkappaB Kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection. J Exp Med 199 (2004) 1641-1650
    • (2004) J Exp Med , vol.199 , pp. 1641-1650
    • Hemmi, H.1    Takeuchi, O.2    Sato, S.3    Yamamoto, M.4    Kaisho, T.5    Sanjo, H.6
  • 23
    • 3042647375 scopus 로고    scopus 로고
    • Differential requirement for TANK-binding kinase-1 in type I interferon responses to Toll-like receptor activation and viral infection
    • Perry A.K., Chow E.K., Goodnough J.B., Yeh W.C., and Cheng G. Differential requirement for TANK-binding kinase-1 in type I interferon responses to Toll-like receptor activation and viral infection. J Exp Med 199 (2004) 1651-1658
    • (2004) J Exp Med , vol.199 , pp. 1651-1658
    • Perry, A.K.1    Chow, E.K.2    Goodnough, J.B.3    Yeh, W.C.4    Cheng, G.5
  • 24
    • 0141923690 scopus 로고    scopus 로고
    • Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling
    • Sato S., Sugiyama M., Yamamoto M., Watanabe Y., Kawai T., Takeda K., et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J Immunol 171 (2003) 4304-4310
    • (2003) J Immunol , vol.171 , pp. 4304-4310
    • Sato, S.1    Sugiyama, M.2    Yamamoto, M.3    Watanabe, Y.4    Kawai, T.5    Takeda, K.6
  • 25
    • 2442642691 scopus 로고    scopus 로고
    • RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappaB activation
    • Meylan E., Burns K., Hofmann K., Blancheteau V., Martinon F., Kelliher M., et al. RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappaB activation. Nat Immunol 5 (2004) 503-507
    • (2004) Nat Immunol , vol.5 , pp. 503-507
    • Meylan, E.1    Burns, K.2    Hofmann, K.3    Blancheteau, V.4    Martinon, F.5    Kelliher, M.6
  • 26
    • 27744561393 scopus 로고    scopus 로고
    • Rip1 mediates the Trif-dependent toll-like receptor 3 and 4-induced NF-kappa B activation but does not contribute to IRF-3 activation
    • Cusson-Hermance N., Lee T.H., Fitzgerald K.A., and Kelliher M.A. Rip1 mediates the Trif-dependent toll-like receptor 3 and 4-induced NF-kappa B activation but does not contribute to IRF-3 activation. J Biol Chem 280 (2005) 36560-36566
    • (2005) J Biol Chem , vol.280 , pp. 36560-36566
    • Cusson-Hermance, N.1    Lee, T.H.2    Fitzgerald, K.A.3    Kelliher, M.A.4
  • 27
    • 24944586285 scopus 로고    scopus 로고
    • Achieving stability of lipopolysaccharide-induced NF-kappaB activation
    • Covert M.W., Leung T.H., Gaston J.E., and Baltimore D. Achieving stability of lipopolysaccharide-induced NF-kappaB activation. Science 309 (2005) 1854-1857
    • (2005) Science , vol.309 , pp. 1854-1857
    • Covert, M.W.1    Leung, T.H.2    Gaston, J.E.3    Baltimore, D.4
  • 28
    • 24944489952 scopus 로고    scopus 로고
    • Stimulus specificity of gene expression programs determined by temporal control of IKK activity
    • Werner S.L., Barken D., and Hoffmann A. Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 309 (2005) 1857-1861
    • (2005) Science , vol.309 , pp. 1857-1861
    • Werner, S.L.1    Barken, D.2    Hoffmann, A.3
  • 29
    • 33748051738 scopus 로고    scopus 로고
    • IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
    • Honda K., and Taniguchi T. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 6 (2006) 644-658
    • (2006) Nat Rev Immunol , vol.6 , pp. 644-658
    • Honda, K.1    Taniguchi, T.2
  • 30
    • 15244349785 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells in immunity
    • Colonna M., Trinchieri G., and Liu Y.J. Plasmacytoid dendritic cells in immunity. Nat Immunol 5 (2004) 1219-1226
    • (2004) Nat Immunol , vol.5 , pp. 1219-1226
    • Colonna, M.1    Trinchieri, G.2    Liu, Y.J.3
  • 31
    • 17644372733 scopus 로고    scopus 로고
    • IPC: professional Type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
    • Liu Y.J. IPC: professional Type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol 23 (2005) 275-306
    • (2005) Annu Rev Immunol , vol.23 , pp. 275-306
    • Liu, Y.J.1
  • 32
    • 0036796384 scopus 로고    scopus 로고
    • Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation
    • Hoshino K., Kaisho T., Iwabe T., Takeuchi O., and Akira S. Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation. Int Immunol 14 (2002) 1225-1231
    • (2002) Int Immunol , vol.14 , pp. 1225-1231
    • Hoshino, K.1    Kaisho, T.2    Iwabe, T.3    Takeuchi, O.4    Akira, S.5
  • 33
    • 0037443644 scopus 로고    scopus 로고
    • The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets
    • Hemmi H., Kaisho T., Takeda K., and Akira S. The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. J Immunol 170 (2003) 3059-3064
    • (2003) J Immunol , vol.170 , pp. 3059-3064
    • Hemmi, H.1    Kaisho, T.2    Takeda, K.3    Akira, S.4
  • 34
    • 5444274514 scopus 로고    scopus 로고
    • Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
    • Kawai T., Sato S., Ishii K.J., Coban C., Hemmi H., Yamamoto M., et al. Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol 5 (2004) 1061-1068
    • (2004) Nat Immunol , vol.5 , pp. 1061-1068
    • Kawai, T.1    Sato, S.2    Ishii, K.J.3    Coban, C.4    Hemmi, H.5    Yamamoto, M.6
  • 35
    • 7444250116 scopus 로고    scopus 로고
    • Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signalling
    • Honda K., Yanai H., Mizutani T., Negishi H., Shimada N., Suzuki N., et al. Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signalling. Proc Natl Acad Sci USA 101 (2004) 15416-15421
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15416-15421
    • Honda, K.1    Yanai, H.2    Mizutani, T.3    Negishi, H.4    Shimada, N.5    Suzuki, N.6
  • 36
    • 20244388983 scopus 로고    scopus 로고
    • Interleukin-1 Receptor-Associated Kinase-1 (IRAK-1) plays an essential role for TLR7- and TLR9-mediated interferon-a_induction
    • Uematsu S., Sato S., Yamamoto M., Hirotani T., Kato H., Takeshita F., et al. Interleukin-1 Receptor-Associated Kinase-1 (IRAK-1) plays an essential role for TLR7- and TLR9-mediated interferon-a_induction. J Exp Med 201 (2005) 915-923
    • (2005) J Exp Med , vol.201 , pp. 915-923
    • Uematsu, S.1    Sato, S.2    Yamamoto, M.3    Hirotani, T.4    Kato, H.5    Takeshita, F.6
  • 37
    • 33645841633 scopus 로고    scopus 로고
    • IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9
    • Hoshino K., Sugiyama T., Matsumoto M., Tanaka T., Saito M., Hemmi H., et al. IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9. Nature 440 (2006) 949-953
    • (2006) Nature , vol.440 , pp. 949-953
    • Hoshino, K.1    Sugiyama, T.2    Matsumoto, M.3    Tanaka, T.4    Saito, M.5    Hemmi, H.6
  • 38
    • 33746028777 scopus 로고    scopus 로고
    • Intracellular pattern recognition receptors in the host response
    • Meylan E., Tschopp J., and Karin M. Intracellular pattern recognition receptors in the host response. Nature 442 (2006) 39-44
    • (2006) Nature , vol.442 , pp. 39-44
    • Meylan, E.1    Tschopp, J.2    Karin, M.3
  • 39
    • 33744539798 scopus 로고    scopus 로고
    • Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses
    • Meylan E., and Tschopp J. Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Mol Cell 22 (2006) 561-569
    • (2006) Mol Cell , vol.22 , pp. 561-569
    • Meylan, E.1    Tschopp, J.2
  • 40
    • 30544451546 scopus 로고    scopus 로고
    • Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
    • Hacker H., Redecke V., Blagoev B., Kratchmarova I., Hsu L.C., Wang G.G., et al. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 439 (2006) 204-207
    • (2006) Nature , vol.439 , pp. 204-207
    • Hacker, H.1    Redecke, V.2    Blagoev, B.3    Kratchmarova, I.4    Hsu, L.C.5    Wang, G.G.6
  • 41
    • 30544447047 scopus 로고    scopus 로고
    • Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
    • Oganesyan G., Saha S.K., Guo B., He J.Q., Shahangian A., Zarnegar B., et al. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature 439 (2006) 208-211
    • (2006) Nature , vol.439 , pp. 208-211
    • Oganesyan, G.1    Saha, S.K.2    Guo, B.3    He, J.Q.4    Shahangian, A.5    Zarnegar, B.6
  • 42
    • 10944228420 scopus 로고    scopus 로고
    • IRAK1 serves as a novel regulator essential for lipopolysaccharide-induced interleukin-10 gene expression
    • Huang Y., Li T., Sane D.C., and Li L. IRAK1 serves as a novel regulator essential for lipopolysaccharide-induced interleukin-10 gene expression. J Biol Chem 279 (2004) 51697-51703
    • (2004) J Biol Chem , vol.279 , pp. 51697-51703
    • Huang, Y.1    Li, T.2    Sane, D.C.3    Li, L.4
  • 43
    • 33645963170 scopus 로고    scopus 로고
    • Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells
    • Shinohara M.L., Lu L., Bu J., Werneck M.B., Kobayashi K.S., Glimcher L.H., et al. Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol 7 (2006) 498-506
    • (2006) Nat Immunol , vol.7 , pp. 498-506
    • Shinohara, M.L.1    Lu, L.2    Bu, J.3    Werneck, M.B.4    Kobayashi, K.S.5    Glimcher, L.H.6
  • 44
    • 33750064259 scopus 로고    scopus 로고
    • Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program
    • Negishi H., Fujita Y., Yanai H., Sakaguchi S., Ouyang X., Shinohara M., et al. Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program. Proc Natl Acad Sci USA 103 (2006) 15136-15141
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15136-15141
    • Negishi, H.1    Fujita, Y.2    Yanai, H.3    Sakaguchi, S.4    Ouyang, X.5    Shinohara, M.6
  • 45
    • 15044345461 scopus 로고    scopus 로고
    • Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
    • Takaoka A., Yanai H., Kondo S., Duncan G., Negishi H., Mizutani T., et al. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 434 (2005) 243-249
    • (2005) Nature , vol.434 , pp. 243-249
    • Takaoka, A.1    Yanai, H.2    Kondo, S.3    Duncan, G.4    Negishi, H.5    Mizutani, T.6
  • 46
    • 33646368404 scopus 로고    scopus 로고
    • A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
    • Graham R.R., Kozyrev S.V., Baechler E.C., Reddy M.V., Plenge R.M., Bauer J.W., et al. A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat Genet 38 (2006) 550-555
    • (2006) Nat Genet , vol.38 , pp. 550-555
    • Graham, R.R.1    Kozyrev, S.V.2    Baechler, E.C.3    Reddy, M.V.4    Plenge, R.M.5    Bauer, J.W.6
  • 47
    • 2442689141 scopus 로고    scopus 로고
    • Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells
    • Tsujimura H., Tamura T., Kong H.J., Nishiyama A., Ishii K.J., Klinman D.M., et al. Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells. J Immunol 172 (2004) 6820-6827
    • (2004) J Immunol , vol.172 , pp. 6820-6827
    • Tsujimura, H.1    Tamura, T.2    Kong, H.J.3    Nishiyama, A.4    Ishii, K.J.5    Klinman, D.M.6
  • 48
    • 29244450802 scopus 로고    scopus 로고
    • Intracellular localization of Toll-like receptor 9 prevents recognition of self-DNA but facilitates access to viral DNA
    • Barton G.M., Kagan J.C., and Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self-DNA but facilitates access to viral DNA. Nat Immunol 7 (2006) 49-56
    • (2006) Nat Immunol , vol.7 , pp. 49-56
    • Barton, G.M.1    Kagan, J.C.2    Medzhitov, R.3
  • 49
    • 17844380477 scopus 로고    scopus 로고
    • Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
    • Honda K., Ohba Y., Yanai H., Negishi H., Mizutani T., Takaoka A., et al. Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature 434 (2005) 1035-1040
    • (2005) Nature , vol.434 , pp. 1035-1040
    • Honda, K.1    Ohba, Y.2    Yanai, H.3    Negishi, H.4    Mizutani, T.5    Takaoka, A.6
  • 50
    • 31344466165 scopus 로고    scopus 로고
    • The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
    • Tabeta K., Hoebe K., Janssen E.M., Du X., Georgel P., Crozat K., et al. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol 7 (2006) 156-164
    • (2006) Nat Immunol , vol.7 , pp. 156-164
    • Tabeta, K.1    Hoebe, K.2    Janssen, E.M.3    Du, X.4    Georgel, P.5    Crozat, K.6
  • 51
    • 33646567507 scopus 로고    scopus 로고
    • The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction
    • Rowe D.C., McGettrick A.F., Latz E., Monks B.G., Gay N.J., Yamamoto M., et al. The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. Proc Natl Acad Sci USA 103 (2006) 6299-6304
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6299-6304
    • Rowe, D.C.1    McGettrick, A.F.2    Latz, E.3    Monks, B.G.4    Gay, N.J.5    Yamamoto, M.6
  • 53
    • 33646908228 scopus 로고    scopus 로고
    • Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling
    • Kagan J.C., and Medzhitov R. Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 125 (2006) 943-955
    • (2006) Cell , vol.125 , pp. 943-955
    • Kagan, J.C.1    Medzhitov, R.2
  • 54
    • 0028949390 scopus 로고
    • RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family
    • Miyake K., Yamashita Y., Ogata M., Sudo T., and Kimoto M. RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. J Immunol 154 (1995) 3333-3340
    • (1995) J Immunol , vol.154 , pp. 3333-3340
    • Miyake, K.1    Yamashita, Y.2    Ogata, M.3    Sudo, T.4    Kimoto, M.5
  • 55
    • 0032146713 scopus 로고    scopus 로고
    • Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression
    • Miyake K., Shimazu R., Kondo J., Niki T., Akashi S., Ogata H., et al. Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. J Immunol 161 (1998) 1348-1353
    • (1998) J Immunol , vol.161 , pp. 1348-1353
    • Miyake, K.1    Shimazu, R.2    Kondo, J.3    Niki, T.4    Akashi, S.5    Ogata, H.6
  • 56
    • 20644450101 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105
    • Divanovic S., Trompette A., Atabani S.F., Madan R., Golenbock D.T., Visintin A., et al. Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat Immunol 6 (2005) 571-578
    • (2005) Nat Immunol , vol.6 , pp. 571-578
    • Divanovic, S.1    Trompette, A.2    Atabani, S.F.3    Madan, R.4    Golenbock, D.T.5    Visintin, A.6
  • 57
    • 2942721674 scopus 로고    scopus 로고
    • ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance
    • Brint E.K., Xu D., Liu H., Dunne A., McKenzie A.N., O'Neill L.A., et al. ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol 5 (2004) 373-379
    • (2004) Nat Immunol , vol.5 , pp. 373-379
    • Brint, E.K.1    Xu, D.2    Liu, H.3    Dunne, A.4    McKenzie, A.N.5    O'Neill, L.A.6
  • 58
    • 0042733592 scopus 로고    scopus 로고
    • SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling
    • Wald D., Qin J., Zhao Z., Qian Y., Naramura M., Tian L., et al. SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nat Immunol 4 (2003) 920-927
    • (2003) Nat Immunol , vol.4 , pp. 920-927
    • Wald, D.1    Qin, J.2    Zhao, Z.3    Qian, Y.4    Naramura, M.5    Tian, L.6
  • 59
    • 2442643942 scopus 로고    scopus 로고
    • Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors
    • Chuang T.H., and Ulevitch R.J. Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors. Nat Immunol 5 (2004) 495-502
    • (2004) Nat Immunol , vol.5 , pp. 495-502
    • Chuang, T.H.1    Ulevitch, R.J.2
  • 61
    • 0042236366 scopus 로고    scopus 로고
    • MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression
    • Janssens S., Burns K., Vercammen E., Tschopp J., and Beyaert R. MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression. FEBS Lett 548 (2003) 103-107
    • (2003) FEBS Lett , vol.548 , pp. 103-107
    • Janssens, S.1    Burns, K.2    Vercammen, E.3    Tschopp, J.4    Beyaert, R.5
  • 62
    • 3042686382 scopus 로고    scopus 로고
    • The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory
    • Hardy M.P., and O'Neill L.A. The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory. J Biol Chem 279 (2004) 27699-27708
    • (2004) J Biol Chem , vol.279 , pp. 27699-27708
    • Hardy, M.P.1    O'Neill, L.A.2
  • 63
    • 31344467156 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
    • Mansell A., Smith R., Doyle S.L., Gray P., Fenner J.E., Crack P.J., et al. Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat Immunol 7 (2006) 148-155
    • (2006) Nat Immunol , vol.7 , pp. 148-155
    • Mansell, A.1    Smith, R.2    Doyle, S.L.3    Gray, P.4    Fenner, J.E.5    Crack, P.J.6
  • 64
    • 30944431519 scopus 로고    scopus 로고
    • TNF receptor-associated factor-1 (TRAF1) negatively regulates Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF)-mediated signaling
    • Su X., Li S., Meng M., Qian W., Xie W., Chen D., et al. TNF receptor-associated factor-1 (TRAF1) negatively regulates Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF)-mediated signaling. Eur J Immunol 36 (2006) 199-206
    • (2006) Eur J Immunol , vol.36 , pp. 199-206
    • Su, X.1    Li, S.2    Meng, M.3    Qian, W.4    Xie, W.5    Chen, D.6
  • 65
    • 23844461233 scopus 로고    scopus 로고
    • TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF
    • Takeshita F., Ishii K.J., Kobiyama K., Kojima Y., Coban C., Sasaki S., et al. TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF. Eur J Immunol 35 (2005) 2477-2485
    • (2005) Eur J Immunol , vol.35 , pp. 2477-2485
    • Takeshita, F.1    Ishii, K.J.2    Kobiyama, K.3    Kojima, Y.4    Coban, C.5    Sasaki, S.6
  • 66
    • 31344463886 scopus 로고    scopus 로고
    • Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
    • Wang Y., Tang Y., Teng L., Wu Y., Zhao X., and Pei G. Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat Immunol 7 (2006) 139-147
    • (2006) Nat Immunol , vol.7 , pp. 139-147
    • Wang, Y.1    Tang, Y.2    Teng, L.3    Wu, Y.4    Zhao, X.5    Pei, G.6
  • 67
    • 5444223519 scopus 로고    scopus 로고
    • The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
    • Boone D.L., Turer E.E., Lee E.G., Ahmad R.C., Wheeler M.T., Tsui C., et al. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat Immunol 5 (2004) 1052-1060
    • (2004) Nat Immunol , vol.5 , pp. 1052-1060
    • Boone, D.L.1    Turer, E.E.2    Lee, E.G.3    Ahmad, R.C.4    Wheeler, M.T.5    Tsui, C.6
  • 68
    • 33744499683 scopus 로고    scopus 로고
    • Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1
    • Saitoh T., Tun-Kyi A., Ryo A., Yamamoto M., Finn G., Fujita T., et al. Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1. Nat Immunol 7 (2006) 598-605
    • (2006) Nat Immunol , vol.7 , pp. 598-605
    • Saitoh, T.1    Tun-Kyi, A.2    Ryo, A.3    Yamamoto, M.4    Finn, G.5    Fujita, T.6
  • 69
    • 33646547951 scopus 로고    scopus 로고
    • Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
    • Gilchrist M., Thorsson V., Li B., Rust A.G., Korb M., Kennedy K., et al. Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. Nature 441 (2006) 173-178
    • (2006) Nature , vol.441 , pp. 173-178
    • Gilchrist, M.1    Thorsson, V.2    Li, B.3    Rust, A.G.4    Korb, M.5    Kennedy, K.6
  • 71
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F., Petrilli V., Mayor A., Tardivel A., and Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440 (2006) 237-241
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 72
    • 33749490571 scopus 로고    scopus 로고
    • Innate immune recognition of, and regulation by, DNA
    • Ishii K.J., and Akira S. Innate immune recognition of, and regulation by, DNA. Trends Immunol 27 (2006) 525-532
    • (2006) Trends Immunol , vol.27 , pp. 525-532
    • Ishii, K.J.1    Akira, S.2


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